JP2014528715A5 - - Google Patents
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- Publication number
- JP2014528715A5 JP2014528715A5 JP2014530916A JP2014530916A JP2014528715A5 JP 2014528715 A5 JP2014528715 A5 JP 2014528715A5 JP 2014530916 A JP2014530916 A JP 2014530916A JP 2014530916 A JP2014530916 A JP 2014530916A JP 2014528715 A5 JP2014528715 A5 JP 2014528715A5
- Authority
- JP
- Japan
- Prior art keywords
- coth
- polypeptide
- seq
- fungal
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 18
- 102000004196 processed proteins & peptides Human genes 0.000 claims 18
- 108090000765 processed proteins & peptides Proteins 0.000 claims 18
- 230000002538 fungal effect Effects 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 239000012634 fragment Substances 0.000 claims 6
- 241000235388 Mucorales Species 0.000 claims 5
- 230000000692 anti-sense effect Effects 0.000 claims 3
- 230000002163 immunogen Effects 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 102000014914 Carrier Proteins Human genes 0.000 claims 2
- 108010078791 Carrier Proteins Proteins 0.000 claims 2
- 108700041152 Endoplasmic Reticulum Chaperone BiP Proteins 0.000 claims 2
- 102100021451 Endoplasmic reticulum chaperone BiP Human genes 0.000 claims 2
- 206010017533 Fungal infection Diseases 0.000 claims 2
- 101150112743 HSPA5 gene Proteins 0.000 claims 2
- 101100111629 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) KAR2 gene Proteins 0.000 claims 2
- 206010061418 Zygomycosis Diseases 0.000 claims 2
- 208000024386 fungal infectious disease Diseases 0.000 claims 2
- 101150028578 grp78 gene Proteins 0.000 claims 2
- 230000036039 immunity Effects 0.000 claims 2
- 108010045069 keyhole-limpet hemocyanin Proteins 0.000 claims 2
- 201000007524 mucormycosis Diseases 0.000 claims 2
- 230000009257 reactivity Effects 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 241000233866 Fungi Species 0.000 claims 1
- 241000270295 Serpentes Species 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000000032 diagnostic agent Substances 0.000 claims 1
- 229940039227 diagnostic agent Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000012202 endocytosis Effects 0.000 claims 1
- 210000002889 endothelial cell Anatomy 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161535257P | 2011-09-15 | 2011-09-15 | |
| US61/535,257 | 2011-09-15 | ||
| PCT/US2012/055659 WO2013040517A2 (en) | 2011-09-15 | 2012-09-14 | IMMUNOTHERAPY AND DIAGNOSIS OF MUCORMYCOSIS USING CotH |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014528715A JP2014528715A (ja) | 2014-10-30 |
| JP2014528715A5 true JP2014528715A5 (enExample) | 2015-11-05 |
Family
ID=47884011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014530916A Pending JP2014528715A (ja) | 2011-09-15 | 2012-09-14 | ＣｏｔＨを用いたムコール菌症の免疫療法および診断法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US9279002B2 (enExample) |
| EP (1) | EP2755681B1 (enExample) |
| JP (1) | JP2014528715A (enExample) |
| CN (1) | CN103998057A (enExample) |
| AU (1) | AU2012308240A1 (enExample) |
| CA (1) | CA2848765A1 (enExample) |
| WO (1) | WO2013040517A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10465233B2 (en) | 2016-03-25 | 2019-11-05 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | Time-resolved nucleic acid hybridization beacons |
| EP3454944B1 (en) * | 2016-05-13 | 2022-07-13 | The Brigham and Women's Hospital, Inc. | Volatile metabolite profiles for the diagnosis and treatment of mucorales fungi |
| US10877037B2 (en) | 2016-11-21 | 2020-12-29 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Fungal toxins and methods related to the same |
| WO2022236145A1 (en) * | 2021-05-06 | 2022-11-10 | Lundquist Institute For Biomedical Innovation At Harbor-Ucla Medical Center | Coth3 binding agents and uses thereof |
| CN114324896A (zh) * | 2021-12-31 | 2022-04-12 | 菲鹏生物股份有限公司 | 特异性结合mucoricin蛋白的试剂的用途和毛霉菌检测试剂盒 |
| CN114568490B (zh) * | 2022-04-01 | 2023-12-19 | 眉山职业技术学院(眉山技师学院) | 雷帕霉素在抑制柑橘青霉菌生长中的应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405712A (en) | 1981-07-01 | 1983-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | LTR-Vectors |
| US4650764A (en) | 1983-04-12 | 1987-03-17 | Wisconsin Alumni Research Foundation | Helper cell |
| US4493795A (en) | 1983-10-17 | 1985-01-15 | Syntex (U.S.A.) Inc. | Synthetic peptide sequences useful in biological and pharmaceutical applications and methods of manufacture |
| US4897355A (en) | 1985-01-07 | 1990-01-30 | Syntex (U.S.A.) Inc. | N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
| JP2561478B2 (ja) | 1986-07-22 | 1996-12-11 | 武田薬品工業株式会社 | グリセリン誘導体 |
| DE3851153T2 (de) | 1987-12-11 | 1995-01-05 | Hughes Howard Med Inst | Genetische modifizierung von endothelialen zellen. |
| EP0456640A1 (en) | 1988-12-13 | 1991-11-21 | UNITED STATES GOVERNMENT as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Genetically engineered endothelial cells and use thereof |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5283173A (en) | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| CA2092195C (en) | 1990-09-21 | 2000-04-18 | Douglas J. Jolly | Retroviral packaging cell line |
| ATE163046T1 (de) | 1990-10-31 | 1998-02-15 | Somatix Therapy Corp | Genetische veränderung von endothelzellen |
| ATE188740T1 (de) | 1991-02-19 | 2000-01-15 | Univ California | Viruspartikel mit veraendertem wirtspektrum |
| US5252479A (en) | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
| US5334761A (en) | 1992-08-28 | 1994-08-02 | Life Technologies, Inc. | Cationic lipids |
| US7914799B2 (en) * | 2001-08-27 | 2011-03-29 | Immunitor USA, Inc. | Anti-fungal composition |
| GB0205378D0 (en) | 2002-03-07 | 2002-04-24 | Royal Holloway University Of L | Bacterial spores |
| EP2049669A2 (en) | 2006-08-09 | 2009-04-22 | DSMIP Assets B.V. | Spore surface displays of bioactive molecules |
| JP2011512817A (ja) * | 2008-02-28 | 2011-04-28 | スリーエム イノベイティブ プロパティズ カンパニー | クロストリジウム・ディフィシル胞子に対する抗体及びその使用 |
| MA33199B1 (fr) | 2009-03-19 | 2012-04-02 | Los Angeles Biomed Res Inst | Compositions de vaccin et procédés pour le traitement de la mucormycose et d'autres maladies fongiques |
| US20110059111A1 (en) * | 2009-09-01 | 2011-03-10 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Mammalian receptors as targets for antibody and active vaccination therapy against mold infections |
-
2012
- 2012-09-14 WO PCT/US2012/055659 patent/WO2013040517A2/en not_active Ceased
- 2012-09-14 AU AU2012308240A patent/AU2012308240A1/en not_active Abandoned
- 2012-09-14 EP EP12831998.5A patent/EP2755681B1/en active Active
- 2012-09-14 CA CA2848765A patent/CA2848765A1/en not_active Abandoned
- 2012-09-14 CN CN201280056226.2A patent/CN103998057A/zh active Pending
- 2012-09-14 JP JP2014530916A patent/JP2014528715A/ja active Pending
- 2012-09-14 US US13/620,563 patent/US9279002B2/en active Active
-
2016
- 2016-02-12 US US15/043,025 patent/US20160159887A1/en not_active Abandoned
-
2018
- 2018-12-11 US US16/216,981 patent/US20190194301A1/en not_active Abandoned
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