JP2014525453A5 - - Google Patents
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- Publication number
- JP2014525453A5 JP2014525453A5 JP2014528562A JP2014528562A JP2014525453A5 JP 2014525453 A5 JP2014525453 A5 JP 2014525453A5 JP 2014528562 A JP2014528562 A JP 2014528562A JP 2014528562 A JP2014528562 A JP 2014528562A JP 2014525453 A5 JP2014525453 A5 JP 2014525453A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- oxo
- dihydropyridine
- alkyl
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161528599P | 2011-08-29 | 2011-08-29 | |
| US61/528,599 | 2011-08-29 | ||
| PCT/US2012/052922 WO2013033258A1 (en) | 2011-08-29 | 2012-08-29 | Antibacterial compounds and methods for use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014525453A JP2014525453A (ja) | 2014-09-29 |
| JP2014525453A5 true JP2014525453A5 (https=) | 2015-11-26 |
Family
ID=47756844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014528562A Ceased JP2014525453A (ja) | 2011-08-29 | 2012-08-29 | 抗菌化合物および使用方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9409905B2 (https=) |
| EP (1) | EP2750504A4 (https=) |
| JP (1) | JP2014525453A (https=) |
| KR (1) | KR20140097118A (https=) |
| CN (1) | CN103889224B (https=) |
| AU (1) | AU2012301953C1 (https=) |
| BR (1) | BR112014004515A2 (https=) |
| CA (1) | CA2846663A1 (https=) |
| CL (1) | CL2014000469A1 (https=) |
| HK (1) | HK1199693A1 (https=) |
| IL (1) | IL231060A (https=) |
| MX (1) | MX2014002298A (https=) |
| WO (1) | WO2013033258A1 (https=) |
| ZA (1) | ZA201402248B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1199792A1 (en) * | 2011-08-29 | 2015-07-24 | Ptc Therapeutics, Inc. | Antibacterial compounds and methods for use |
| WO2014139388A1 (en) * | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
| WO2014157382A1 (ja) * | 2013-03-29 | 2014-10-02 | 味の素株式会社 | スフィンゴシンキナーゼ阻害剤 |
| WO2016039939A1 (en) * | 2014-09-09 | 2016-03-17 | Ptc Therapeutics, Inc. | Bicyclic and tricyclic substituted 2-pyridinone antibacterial compounds |
| WO2016039937A1 (en) * | 2014-09-09 | 2016-03-17 | Ptc Therapeutics, Inc. | Bicyclic and tricyclic substituted 2-pyridinone antibacterial compounds |
| WO2016109706A1 (en) * | 2014-12-31 | 2016-07-07 | Ptc Therapeutics, Inc. | Fused polycyclic 2-pyridinone antibacterial compounds |
| WO2018200571A1 (en) | 2017-04-25 | 2018-11-01 | Arbutus Biopharma Corporation | Substituted 2,3-dihydro-1h-indene analogs and methods using same |
| JP7153645B2 (ja) * | 2017-06-08 | 2022-10-14 | 三井化学アグロ株式会社 | ピリドン化合物およびそれを有効成分とする農園芸用殺菌剤 |
| CN107325080B (zh) * | 2017-08-30 | 2020-05-12 | 延边大学 | 含三嗪或氨基胍结构的咔唑类衍生物的制备方法及其抗菌应用 |
| GB2571950A (en) | 2018-03-13 | 2019-09-18 | Azad Pharma Ag | New polymorph and new path to synthesize tafamidis |
| US12083118B2 (en) | 2018-03-29 | 2024-09-10 | Arbutus Biopharma Corporation | Substituted 1,1′-biphenyl compounds, analogues thereof, and methods using same |
| CN108659091B (zh) * | 2018-05-24 | 2020-07-03 | 烟台大学 | 夫西地酸衍生物及其合成制备方法和应用 |
| JP2021534246A (ja) * | 2018-08-16 | 2021-12-09 | レクレオ ファーマシューティカルス アイエヌシー | １，３，４，９−テトラヒドロ−２ｈ−ピリド［３，４−ｂ］インドール誘導体化合物及びその使用 |
| CN109329290A (zh) * | 2018-10-11 | 2019-02-15 | 四川省兰月科技有限公司 | 防治猕猴桃、柑橘黄化病的农药组合物 |
| CN109485601B (zh) * | 2018-12-23 | 2020-06-30 | 沧州普瑞东方科技有限公司 | 2,6-二卤吡啶-3-羧酸的合成方法 |
| CN111521706A (zh) * | 2020-05-11 | 2020-08-11 | 苏州必宜生物科技有限公司 | 一种快速检测血浆中头孢克肟浓度的方法 |
| AU2022424463A1 (en) * | 2021-12-28 | 2024-07-18 | Adeka Corporation | Aryl tetrahydropyridine derivative or salt thereof, pest control agent containing same, and method for use thereof |
| CN115960031B (zh) * | 2023-01-06 | 2024-09-10 | 暨南大学 | 一种四氢异吲哚酮类化合物及其制备方法和应用 |
| CN119569650A (zh) * | 2024-12-05 | 2025-03-07 | 凯美克(上海)医药科技有限公司 | 一种7-溴-2-氯喹啉-4-醇的合成方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3703582A (en) | 1970-04-20 | 1972-11-21 | Merck & Co Inc | Aryl pyridine carboxylic acids in the treatment of inflammation |
| US3948903A (en) * | 1972-12-15 | 1976-04-06 | Parke, Davis & Company | Substituted N-(1,2-dihydro-2-oxonicotinyl)-cephalexins and -cephaloglycins |
| US3954734A (en) | 1974-01-21 | 1976-05-04 | Parke, Davis & Company | Novel antibacterial amide compounds and process means for producing the same |
| JPS5643288A (en) | 1979-09-18 | 1981-04-21 | Meiji Seika Kaisha Ltd | Cephalosporin derivative and its preparation |
| JPS5651488A (en) | 1979-10-02 | 1981-05-09 | Meiji Seika Kaisha Ltd | Penicillin derivative and its preparation |
| DE3338846A1 (de) * | 1982-10-29 | 1984-05-03 | Toyama Chemical Co. Ltd., Tokyo | Neue 4-oxo-1,4-dihydronicotinsaeurederivate und salze derselben, verfahren zu ihrer herstellung und antibakterielle mittel mit einem gehalt derselben |
| EP0308020A3 (en) | 1987-09-18 | 1990-12-05 | Merck & Co. Inc. | 5-(aryl and heteroaryl)-6-(aryl and heteroaryl)-1,2-dihydro-2-oxo 3-pyridinecarboxylic acids and derivatives thereof |
| GB8809481D0 (en) | 1988-04-21 | 1988-05-25 | Smith Kline French Lab | Chemical compounds |
| IE911704A1 (en) * | 1990-05-21 | 1991-12-04 | Smith Kline French Lab | Chemical compounds |
| DE19639817A1 (de) * | 1996-09-27 | 1998-04-02 | Hoechst Ag | Verwendung von 1-Hydroxy-2-pyridonen zur Behandlung von Hautinfektionen |
| CN1231161A (zh) | 1998-07-07 | 1999-10-13 | 邱泽国 | 全自动多功能超声波洗碗机 |
| EP1343763A1 (en) | 2000-11-20 | 2003-09-17 | Bristol-Myers Squibb Company | Pyrodone derivatives as ap2 inhibitors |
| US7482366B2 (en) | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
| ATE448784T1 (de) * | 2002-02-14 | 2009-12-15 | Pharmacia Corp | Substituierte pyridinone als modulatoren für p38 map kinase |
| CN101531631B (zh) | 2002-02-14 | 2011-09-28 | 法玛西雅公司 | 作为p38map激酶调节剂的取代吡啶酮类 |
| CL2004002050A1 (es) | 2003-08-13 | 2005-06-03 | Pharmacia Corp Sa Organizada B | Compuestos derivados de piridinonas sustituidas; su uso en el tratamiento de afecciones causadas o exacerbadas por actividad p38 map kinasa y/o tnf no regulada, tales como inflamaciones, tumores, sida y otros. |
| TWI360539B (en) | 2004-10-28 | 2012-03-21 | Shionogi & Co | 3-carbamoyl-2-pyridone derivatives |
| CN101171247A (zh) * | 2005-03-04 | 2008-04-30 | 阿斯利康(瑞典)有限公司 | 作为dna促旋酶和拓扑异构酶抑制剂的吡咯衍生物 |
| WO2006117762A2 (en) | 2005-05-03 | 2006-11-09 | Ranbaxy Laboratories Limited | Antimicrobial agents |
| CA2713128C (en) | 2008-01-25 | 2016-04-05 | Gruenenthal Gmbh | Pharmaceutical dosage form |
| HK1199792A1 (en) * | 2011-08-29 | 2015-07-24 | Ptc Therapeutics, Inc. | Antibacterial compounds and methods for use |
| CA2846655A1 (en) * | 2011-08-29 | 2013-03-07 | Arthur Branstrom | Antibacterial compounds and methods for use |
-
2012
- 2012-08-29 AU AU2012301953A patent/AU2012301953C1/en not_active Ceased
- 2012-08-29 KR KR1020147008210A patent/KR20140097118A/ko not_active Withdrawn
- 2012-08-29 CA CA2846663A patent/CA2846663A1/en not_active Abandoned
- 2012-08-29 JP JP2014528562A patent/JP2014525453A/ja not_active Ceased
- 2012-08-29 WO PCT/US2012/052922 patent/WO2013033258A1/en not_active Ceased
- 2012-08-29 BR BR112014004515A patent/BR112014004515A2/pt not_active IP Right Cessation
- 2012-08-29 US US14/241,506 patent/US9409905B2/en not_active Expired - Fee Related
- 2012-08-29 HK HK15100101.9A patent/HK1199693A1/xx unknown
- 2012-08-29 CN CN201280051906.5A patent/CN103889224B/zh not_active Expired - Fee Related
- 2012-08-29 MX MX2014002298A patent/MX2014002298A/es unknown
- 2012-08-29 EP EP12828218.3A patent/EP2750504A4/en not_active Withdrawn
-
2014
- 2014-02-20 IL IL231060A patent/IL231060A/en not_active IP Right Cessation
- 2014-02-26 CL CL2014000469A patent/CL2014000469A1/es unknown
- 2014-03-26 ZA ZA2014/02248A patent/ZA201402248B/en unknown
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