JP2014524929A5 - - Google Patents
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- Publication number
- JP2014524929A5 JP2014524929A5 JP2014522117A JP2014522117A JP2014524929A5 JP 2014524929 A5 JP2014524929 A5 JP 2014524929A5 JP 2014522117 A JP2014522117 A JP 2014522117A JP 2014522117 A JP2014522117 A JP 2014522117A JP 2014524929 A5 JP2014524929 A5 JP 2014524929A5
- Authority
- JP
- Japan
- Prior art keywords
- prasugrel
- acid
- base
- formula
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11175721 | 2011-07-28 | ||
| EP11175721.7 | 2011-07-28 | ||
| US201161574248P | 2011-07-29 | 2011-07-29 | |
| US61/574,248 | 2011-07-29 | ||
| EP12150675.2 | 2012-01-10 | ||
| EP12150675 | 2012-01-10 | ||
| PCT/EP2012/064852 WO2013014295A1 (en) | 2011-07-28 | 2012-07-30 | Process for preparing prasugrel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014524929A JP2014524929A (ja) | 2014-09-25 |
| JP2014524929A5 true JP2014524929A5 (https=) | 2015-05-21 |
Family
ID=47600543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014522117A Pending JP2014524929A (ja) | 2011-07-28 | 2012-07-30 | プラスグレルの調製方法 |
Country Status (4)
| Country | Link |
|---|---|
| EP (2) | EP2736509B1 (https=) |
| JP (1) | JP2014524929A (https=) |
| ES (1) | ES2557199T3 (https=) |
| WO (1) | WO2013014295A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105085541A (zh) * | 2014-05-07 | 2015-11-25 | 江苏先声药业有限公司 | 一种普拉格雷类似物的制备方法 |
| CN104592250B (zh) * | 2015-01-15 | 2016-05-11 | 新发药业有限公司 | 一种低成本的普拉格雷的环保制备方法 |
| CN106117240A (zh) * | 2016-06-09 | 2016-11-16 | 青岛辰达生物科技有限公司 | 一种制备抗血栓药物普拉格雷的方法 |
| HU231079B1 (hu) | 2016-06-23 | 2020-06-29 | Richter Gedeon Nyrt. | Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával |
| WO2018073437A1 (en) | 2016-10-21 | 2018-04-26 | Laboratorios Lesvi, Sl | Pharmaceutical formulations of prasugrel and processes for the preparation thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI101150B (fi) | 1991-09-09 | 1998-04-30 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi |
| JP4001199B2 (ja) * | 2000-07-06 | 2007-10-31 | 第一三共株式会社 | ヒドロピリジン誘導体酸付加塩 |
| ATE398624T1 (de) | 2000-07-06 | 2008-07-15 | Daiichi Sankyo Co Ltd | Säure-additionssalze von hydropyridinderivaten |
| TWI392681B (zh) * | 2006-04-06 | 2013-04-11 | Daiichi Sankyo Co Ltd | 高純度普拉格雷及其酸加成鹽之製法 |
| US20100261908A1 (en) * | 2007-11-09 | 2010-10-14 | Dr. Reddy's Laboratories Ltd. | Processes for the preparation of prasugrel , and its salts and polymorphs |
| CN101177430A (zh) * | 2007-12-11 | 2008-05-14 | 鲁南制药集团股份有限公司 | 氢化吡啶衍生物及其盐的制备方法 |
| EP2112155B1 (en) | 2008-04-25 | 2010-09-29 | Sandoz AG | Hydrogensulfate salt of 2-acetoxy-5-(a-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine and its preparation |
| CZ2009763A3 (cs) | 2009-11-16 | 2011-05-25 | Zentiva, K. S. | Zpusob výroby vysoce cistého 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu známého pod nechráneným názvem prasugrel a jeho nových farmaceuticky prijatelných solí. |
| US9000186B2 (en) * | 2011-02-01 | 2015-04-07 | Kyowa Hakko Kirin Co., Ltd. | Ring-fused heterocyclic derivative |
-
2012
- 2012-07-30 JP JP2014522117A patent/JP2014524929A/ja active Pending
- 2012-07-30 EP EP12740371.5A patent/EP2736509B1/en active Active
- 2012-07-30 WO PCT/EP2012/064852 patent/WO2013014295A1/en not_active Ceased
- 2012-07-30 EP EP15186114.3A patent/EP2985023A1/en not_active Withdrawn
- 2012-07-30 ES ES12740371.5T patent/ES2557199T3/es active Active
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