JP2014520105A5 - - Google Patents

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Publication number
JP2014520105A5
JP2014520105A5 JP2014513858A JP2014513858A JP2014520105A5 JP 2014520105 A5 JP2014520105 A5 JP 2014520105A5 JP 2014513858 A JP2014513858 A JP 2014513858A JP 2014513858 A JP2014513858 A JP 2014513858A JP 2014520105 A5 JP2014520105 A5 JP 2014520105A5
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JP
Japan
Prior art keywords
polymer
polymer according
tumor
group
active agent
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JP2014513858A
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English (en)
Japanese (ja)
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JP2014520105A (ja
JP6158177B2 (ja
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Priority claimed from PCT/AU2012/000647 external-priority patent/WO2012167309A1/en
Publication of JP2014520105A publication Critical patent/JP2014520105A/ja
Publication of JP2014520105A5 publication Critical patent/JP2014520105A5/ja
Application granted granted Critical
Publication of JP6158177B2 publication Critical patent/JP6158177B2/ja
Active legal-status Critical Current
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JP2014513858A 2011-06-06 2012-06-06 高分子 Active JP6158177B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161493886P 2011-06-06 2011-06-06
US61/493,886 2011-06-06
PCT/AU2012/000647 WO2012167309A1 (en) 2011-06-06 2012-06-06 Macromolecules

Publications (3)

Publication Number Publication Date
JP2014520105A JP2014520105A (ja) 2014-08-21
JP2014520105A5 true JP2014520105A5 (enExample) 2015-07-23
JP6158177B2 JP6158177B2 (ja) 2017-07-05

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ID=47295262

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014513858A Active JP6158177B2 (ja) 2011-06-06 2012-06-06 高分子

Country Status (18)

Country Link
US (2) US9744246B2 (enExample)
EP (1) EP2729179B1 (enExample)
JP (1) JP6158177B2 (enExample)
KR (1) KR101941318B1 (enExample)
CN (2) CN110124051B (enExample)
AU (1) AU2012267200B2 (enExample)
BR (1) BR112013031556B1 (enExample)
CA (1) CA2837979C (enExample)
DK (1) DK2729179T3 (enExample)
ES (1) ES2834992T3 (enExample)
HR (1) HRP20201998T1 (enExample)
HU (1) HUE052285T2 (enExample)
IN (1) IN2014DN00101A (enExample)
LT (1) LT2729179T (enExample)
PL (1) PL2729179T3 (enExample)
PT (1) PT2729179T (enExample)
SI (1) SI2729179T1 (enExample)
WO (1) WO2012167309A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180326081A1 (en) * 2011-06-06 2018-11-15 Starpharma Pty Ltd Macromolecules
EP2996726A1 (fr) * 2013-05-16 2016-03-23 Université de Strasbourg Composés dendritiques comprenant un agent chélatant, fluorochrome ou agent de reconnaissance, compositions les comprenant et leurs utilisations
WO2015035446A1 (en) * 2013-09-10 2015-03-19 Starpharma Pty Ltd Macromolecules of dendrimer-platinum conjugates
EP3152248B1 (en) 2014-06-06 2019-10-09 Starpharma Pty Ltd Dendrimer-drug conjugates
CA2987322C (en) 2015-08-11 2020-02-11 Coherent Biopharma Multi-ligand drug conjugates and uses thereof
CN106554330B (zh) * 2015-09-26 2019-07-05 南京友怡医药科技有限公司 水溶性多西他赛抗癌药物化合物及其制备方法和应用
CN106554329B (zh) * 2015-09-26 2019-07-05 南京友怡医药科技有限公司 水溶性紫杉醇抗癌药物化合物及其制备方法和应用
WO2017068051A1 (en) * 2015-10-21 2017-04-27 Lek Pharmaceuticals D.D. Peg-based dendron and process for producing the same
WO2017135893A1 (en) * 2016-02-05 2017-08-10 Nipsea Technologies Pte Ltd Aqueous dendritic amine coatings
US20190142953A1 (en) * 2016-05-10 2019-05-16 Massachusetts Institute Of Technology Dendrimer-Drug Conjugates, Hydrogel Compositions, and Methods
TWI773730B (zh) * 2017-02-22 2022-08-11 瑞典商阿斯特捷利康公司 治療性樹枝狀聚合物
EP3778628A4 (en) * 2018-03-29 2021-11-24 NOF Corporation DEGRADABLE POLYETHYLENE GLYCOL CONJUGATE
US12071517B2 (en) * 2018-07-19 2024-08-27 Starpharma Pty Ltd. Therapeutic dendrimer
EP3823961A4 (en) * 2018-07-19 2022-06-08 Starpharma Pty Limited THERAPEUTIC DENDRIMER
TWI831817B (zh) * 2018-08-17 2024-02-11 瑞典商阿斯特捷利康公司 治療癌症之方法
TWI856967B (zh) 2018-08-17 2024-10-01 瑞典商阿斯特捷利康公司 樹枝狀體配製物
CN113056469B (zh) 2018-11-20 2025-05-23 星法马私人有限公司 治疗性树状聚体
AU2019390489B2 (en) * 2018-11-29 2023-08-17 Starpharma Pty Ltd Dendrimer for therapy and imaging
EP4021511A4 (en) * 2019-08-28 2023-10-04 Starpharma Pty Ltd TARGETED DENDRIMER CONJUGATES
CN114585389A (zh) * 2019-09-26 2022-06-03 星法马私人有限公司 治疗性树枝状大分子
WO2021213492A1 (zh) * 2020-04-24 2021-10-28 上海森辉医药有限公司 一类载药的大分子及其制备方法
AU2021284918A1 (en) * 2020-06-03 2023-01-05 Starpharma Pty Ltd Therapeutic conjugates
JP7880863B2 (ja) * 2020-08-25 2026-06-26 上海森輝医薬有限公司 薬剤を担持する高分子及びその調製方法
US20230263900A1 (en) * 2020-08-31 2023-08-24 Starpharma Pty Ltd. Dendrimer-drug conjugate
EP3973952B1 (en) * 2020-09-24 2024-02-14 Ocular Therapeutix, Inc. Sustained release biodegradable intracanalicular inserts comprising a hydrogel and cyclosporine
EP4216929A1 (en) * 2020-09-24 2023-08-02 Ocular Therapeutix, Inc. Sustained release biodegradable intracanalicular inserts comprising a hydrogel and an active agent
CN117164357B (zh) * 2023-01-03 2024-07-19 广东捷成科创电子股份有限公司 一种五元系大功率型压电陶瓷材料及其制备方法
TW202448514A (zh) * 2023-05-08 2024-12-16 大陸商上海森輝醫藥有限公司 抗真菌藥的載藥大分子及其製備方法
CN118063414B (zh) * 2024-02-29 2026-04-28 常州大学 一种半胱氨酸-多西他赛偶联物及其制备方法和应用
WO2026046228A1 (zh) * 2024-08-27 2026-03-05 苏州拓界医药有限公司 树枝状聚合物偶联物及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840900A (en) * 1993-10-20 1998-11-24 Enzon, Inc. High molecular weight polymer-based prodrugs
US7261875B2 (en) * 2001-12-21 2007-08-28 Board Of Regents, The University Of Texas System Dendritic poly (amino acid) carriers and methods of use
CN101102787A (zh) * 2004-08-09 2008-01-09 艾丽奥斯生物制药有限公司 合成的超糖基化、抗蛋白酶的多肽变体、口服制剂及其使用方法
WO2007082331A1 (en) * 2006-01-20 2007-07-26 Starpharma Pty Limited Modified macromolecule
CN101002945B (zh) * 2006-01-20 2012-09-05 清华大学 一种用于肿瘤治疗的新型复合物
WO2008017125A1 (en) * 2006-08-11 2008-02-14 Starpharma Pty Ltd Targeted polylysine dendrimer therapeutic agent
CN102076331B (zh) 2008-06-26 2013-12-18 普罗林科斯有限责任公司 具有可控的药物释放速率的前药和药物-大分子轭合物
WO2011072290A2 (en) * 2009-12-11 2011-06-16 The Regents Of The University Of Michigan Targeted dendrimer-drug conjugates
EP2566334B1 (en) 2010-05-05 2018-04-18 Prolynx, LLC Controlled drug release from solid supports
WO2011140376A1 (en) 2010-05-05 2011-11-10 Prolynx Llc Controlled drug release from dendrimers
WO2011140393A1 (en) 2010-05-05 2011-11-10 Prolynx Llc Controlled release from macromolecular conjugates

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