JP2014518232A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014518232A5 JP2014518232A5 JP2014517657A JP2014517657A JP2014518232A5 JP 2014518232 A5 JP2014518232 A5 JP 2014518232A5 JP 2014517657 A JP2014517657 A JP 2014517657A JP 2014517657 A JP2014517657 A JP 2014517657A JP 2014518232 A5 JP2014518232 A5 JP 2014518232A5
- Authority
- JP
- Japan
- Prior art keywords
- applicable
- acceptable
- vehicle
- stirring
- room temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000000203 mixture Substances 0.000 description 3
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- MLDQJTXFUGDVEO-UHFFFAOYSA-N BAY-43-9006 Chemical compound C1=NC(C(=O)NC)=CC(OC=2C=CC(NC(=O)NC=3C=C(C(Cl)=CC=3)C(F)(F)F)=CC=2)=C1 MLDQJTXFUGDVEO-UHFFFAOYSA-N 0.000 description 1
- 239000005511 L01XE05 - Sorafenib Substances 0.000 description 1
- 241000036848 Porzana carolina Species 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229960003787 sorafenib Drugs 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11171715.3 | 2011-06-28 | ||
| EP11171715 | 2011-06-28 | ||
| EP12161989.4 | 2012-03-29 | ||
| EP12161989 | 2012-03-29 | ||
| PCT/EP2012/062354 WO2013000909A1 (en) | 2011-06-28 | 2012-06-26 | Topical ophthalmological pharmaceutical composition containing sorafenib |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014518232A JP2014518232A (ja) | 2014-07-28 |
| JP2014518232A5 true JP2014518232A5 (enExample) | 2014-09-04 |
Family
ID=46397246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014517657A Ceased JP2014518232A (ja) | 2011-06-28 | 2012-06-26 | ソラフェニブを含有する眼科用局所医薬組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140235678A1 (enExample) |
| EP (1) | EP2726057A1 (enExample) |
| JP (1) | JP2014518232A (enExample) |
| CN (1) | CN103764118A (enExample) |
| CA (1) | CA2840491A1 (enExample) |
| WO (1) | WO2013000909A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006034797A1 (en) | 2004-09-29 | 2006-04-06 | Bayer Healthcare Ag | Thermodynamically stable form of bay 43-9006 tosylate |
| KR101335932B1 (ko) | 2005-03-07 | 2013-12-04 | 바이엘 헬스케어 엘엘씨 | 암의 치료를 위한 오메가-카르복시아릴 치환된 디페닐우레아를 포함하는 제약 조성물 |
| AR081060A1 (es) | 2010-04-15 | 2012-06-06 | Bayer Schering Pharma Ag | Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida |
| US9206423B2 (en) * | 2012-12-30 | 2015-12-08 | The Regents Of The University Of California | Methods of modulating compliance of the trabecular meshwork |
| US8901144B2 (en) | 2013-02-07 | 2014-12-02 | Scifluor Life Sciences, Llc | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives |
| WO2014124302A1 (en) | 2013-02-07 | 2014-08-14 | Scifluor Life Sciences, Llc | Fluorinated integrin antagonists |
| JP6612232B2 (ja) | 2013-08-28 | 2019-11-27 | クラウン バイオサイエンス インコーポレイテッド（タイカン） | 対象のマルチキナーゼ阻害剤に対する応答性を予測する遺伝子発現シグネチャ、及びその使用 |
| CA2963872C (en) * | 2014-10-09 | 2023-09-12 | Distretto Tecnologico Sicilia Micro E Nano Sistemi S.C.A.R.L. | Nanostructured formulations for the delivery of silibinin and other active ingredients for treating ocular diseases |
| WO2016134223A2 (en) | 2015-02-19 | 2016-08-25 | Scifluor Life Sciences, Inc. | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof |
| JP2018520093A (ja) * | 2015-05-05 | 2018-07-26 | シヴィダ・ユーエス・インコーポレイテッドＰｓｉｖｉｄａ Ｕｓ， Ｉｎｃ． | 注射可能なデポー製剤 |
| ES2971096T3 (es) * | 2015-06-06 | 2024-06-03 | Cloudbreak Therapeutics Llc | Composiciones y métodos para tratar el terigio |
| TWI664965B (zh) * | 2015-06-22 | 2019-07-11 | 新源生物科技股份有限公司 | 酪胺酸激酶抑制劑之眼用調配物、其使用方法、及其製備方法 |
| CN109152769A (zh) * | 2016-05-25 | 2019-01-04 | 参天制药株式会社 | 西罗莫司用于治疗伴有持续性水肿的渗出性年龄相关性黄斑变性的用途 |
| CA3026118A1 (en) | 2016-06-02 | 2017-12-07 | Cloudbreak Therapeutics, Llc | Compositions and methods of using nintedanib for treating ocular diseases with abnormal neovascularization |
| CA3160153A1 (en) | 2019-12-17 | 2021-06-24 | Michelle Machacek | Prmt5 inhibitors |
| CN114288242B (zh) * | 2022-01-14 | 2023-05-23 | 中国药科大学 | 一种索拉非尼纳米混悬滴眼液及其制备方法 |
| WO2025169089A1 (en) | 2024-02-05 | 2025-08-14 | Sun Pharmaceutical Industries Limited | Ophthalmic compositions of tyrosine kinase inhibitors and their uses |
| CN117982434A (zh) * | 2024-02-22 | 2024-05-07 | 中国药科大学 | 一种治疗湿性年龄相关性黄斑病变的对甲苯磺酸索拉非尼聚乳酸微球 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1140840B1 (en) | 1999-01-13 | 2006-03-22 | Bayer Pharmaceuticals Corp. | -g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| DE602004007382T2 (de) | 2003-05-20 | 2008-04-17 | Bayer Pharmaceuticals Corp., West Haven | Diaryl-harnstoffe für durch pdgfr vermittelte krankheiten |
| WO2006034797A1 (en) | 2004-09-29 | 2006-04-06 | Bayer Healthcare Ag | Thermodynamically stable form of bay 43-9006 tosylate |
| CA2607608A1 (en) | 2005-05-10 | 2006-11-16 | Alcon, Inc. | Suspension formulations of nepafenac and other ophthalmic drugs for topical treatment of ophthalmic disorders |
| CA2611720A1 (en) | 2005-06-08 | 2006-12-14 | Targegen, Inc. | Methods and compositions for the treatment of ocular disorders |
| PL1968594T3 (pl) | 2005-11-29 | 2011-03-31 | Glaxosmithkline Llc | Leczenie zaburzeń neowaskularyzacyjnych oka, takich jak zwyrodnienie plamki żółtej, rozszerzenie naczyń siatkówki w zespole Hippla i Lindaua, zapalenie błony naczyniowej oka i obrzęk plamki |
| WO2007068381A1 (en) * | 2005-12-15 | 2007-06-21 | Bayer Healthcare Ag | Diaryl ureas for treating inflammatory skin, eye and/or ear diseases |
| US20070149593A1 (en) | 2005-12-23 | 2007-06-28 | Alcon, Inc. | PHARMACEUTICAL FORMULATION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE |
| WO2008027341A2 (en) | 2006-08-30 | 2008-03-06 | Merck & Co., Inc. | Topical ophthalmic formulations |
| EP2156834A1 (en) * | 2008-08-08 | 2010-02-24 | S.I.F.I - Società Industria Farmaceutica Italiana - S.P.A. | Ophthalmic pharmaceutical compositions comprising Sorafenib for the treatment of neoangiogenic pathologies of the eye |
| EP3165606A1 (en) | 2009-05-01 | 2017-05-10 | Ophthotech Corporation | Methods for treating or preventing ophthalmological diseases |
| CN102573477A (zh) | 2009-07-16 | 2012-07-11 | 葛兰素惠尔康制造业私人有限公司 | 治疗方法 |
-
2012
- 2012-06-26 CA CA2840491A patent/CA2840491A1/en not_active Abandoned
- 2012-06-26 US US14/129,557 patent/US20140235678A1/en not_active Abandoned
- 2012-06-26 EP EP12730512.6A patent/EP2726057A1/en not_active Withdrawn
- 2012-06-26 CN CN201280031848.XA patent/CN103764118A/zh active Pending
- 2012-06-26 JP JP2014517657A patent/JP2014518232A/ja not_active Ceased
- 2012-06-26 WO PCT/EP2012/062354 patent/WO2013000909A1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20191366T1 (hr) | Injekcijski pripravak | |
| Moritz et al. | Mesoporous materials as elements of modern drug delivery systems for anti-inflammatory agents: A review of recent achievements | |
| EP3339305A4 (en) | INDOLE DERIVATIVE PRODUCTION METHOD AND USE THEREOF IN PHARMACEUTICAL MEDICAMENTS | |
| CY1109265T1 (el) | Συνθεσεις που συμπεριλαμβανουν δροσπιρενονη μοριακα διασπαρμενη | |
| JP2023078155A (ja) | 剤形およびそれらの使用 | |
| WO2013188792A3 (en) | Neuroactive steroids, compositions, and uses thereof | |
| UA122346C2 (uk) | ТЕТРАГІДРО-1H-ПІРИДО[3,4-b]ІНДОЛЬНІ АНТИЕСТРОГЕННІ ЛІКАРСЬКІ ПРЕПАРАТИ | |
| WO2010084505A3 (en) | Stable topical formulation comprising voriconazole | |
| JP2018500343A5 (enExample) | ||
| WO2012142511A3 (en) | Orthomolecular compositions and their use in stabilizing the extracellular matrix | |
| WO2015018380A3 (en) | Therapeutic nanoparticles and the preparation methods thereof | |
| BR112014014262A2 (pt) | nanopartículas; composição farmacêutica; método de administrar um ou mais agentes terapêuticos, profiláticos, e/ou diagnósticos a um paciente em necessidade dos mesmos e método de preparação das partículas. | |
| BR112014011841A2 (pt) | material de entrega de fármacos hidrofóbicos, método para a produção do mesmo e métodos para a entrega de uma composição de entrega de fármacos | |
| JP2012517987A5 (ja) | 吸入用の医薬組成物のｆｐｄ特性を設定する方法 | |
| EP2987791A4 (en) | Novel 3- (4- (benzyloxy) phenyl) hexadecanoic acid derivative, process for the preparation thereof, and pharmaceutical composition for the prevention and treatment of metabolic disorders, therefore, as an active ingredient | |
| JP2015524444A5 (enExample) | ||
| WO2013132457A3 (en) | Nanocrystalline solid dispersion compositions and process of preparation thereof | |
| IL188643A (en) | Derivatives – n (troaryl) –1 – troarylalkyl – 1h – indole – 2– carboxamide, process for the production of derivatives, drug, pharmaceutical composition and use of derivatives for drug production. | |
| EP2717914A4 (en) | DELAYED FORMULATIONS FOR THE ADMINISTRATION OF PROTEINS AND FOR THEIR MANUFACTURE | |
| HK1217092A1 (zh) | 治疗性化合物及其用途 | |
| MA37455A1 (fr) | Utilisation d'un dérivé de pyrazole dans le traitement d'exacerbations aigues d'une maladie pulmonaire obstructive chronique | |
| EP3442542A4 (en) | NANOPARTICLE, DOSAGE FORM WITH CONTROLLED RELEASE, AND METHOD FOR RELEASING AN IMMUNOTHERAPEUTIC | |
| ZA201500920B (en) | 3-substituted estra-1,3,5(10),16-tetraene derivatives ,methods for the production thereof ,pharmaceutical preparations contaning same,and use thereof for the production of medicaments | |
| MX354073B (es) | Formulacion farmaceutica estable para administracion oral que comprende levocetirizina o una de sus sales aceptables desde el punto de vista farmaceutico, y montelukast o una de sus sales aceptables desde el punto de vista farmaceutico. | |
| AR075614A1 (es) | Piperidinas 1, 4-disustituidas, una composicion farmaceutica que las comprende y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por los receptores v1a de vasopresina. |