JP2014517038A5 - - Google Patents
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- Publication number
- JP2014517038A5 JP2014517038A5 JP2014515934A JP2014515934A JP2014517038A5 JP 2014517038 A5 JP2014517038 A5 JP 2014517038A5 JP 2014515934 A JP2014515934 A JP 2014515934A JP 2014515934 A JP2014515934 A JP 2014515934A JP 2014517038 A5 JP2014517038 A5 JP 2014517038A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- wound
- skin
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010052428 Wound Diseases 0.000 claims description 16
- 208000027418 Wounds and injury Diseases 0.000 claims description 16
- 206010072170 Skin wound Diseases 0.000 claims description 14
- 230000029663 wound healing Effects 0.000 claims description 12
- 239000011159 matrix material Substances 0.000 claims description 5
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 2
- 206010073306 Exposure to radiation Diseases 0.000 claims description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 2
- 230000001413 cellular effect Effects 0.000 claims description 2
- 206010012601 diabetes mellitus Diseases 0.000 claims description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 2
- 230000002500 effect on skin Effects 0.000 claims description 2
- 238000007918 intramuscular administration Methods 0.000 claims description 2
- 230000037311 normal skin Effects 0.000 claims description 2
- 230000005855 radiation Effects 0.000 claims description 2
- 238000007920 subcutaneous administration Methods 0.000 claims description 2
- 230000000699 topical effect Effects 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 15
- 238000000034 method Methods 0.000 description 26
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161496472P | 2011-06-13 | 2011-06-13 | |
| US61/496,472 | 2011-06-13 | ||
| US201161528053P | 2011-08-26 | 2011-08-26 | |
| US61/528,053 | 2011-08-26 | ||
| PCT/US2012/042165 WO2012174056A1 (en) | 2011-06-13 | 2012-06-13 | Mitigation of cutaneous injury with il-12 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014517038A JP2014517038A (ja) | 2014-07-17 |
| JP2014517038A5 true JP2014517038A5 (enExample) | 2015-07-30 |
| JP6005736B2 JP6005736B2 (ja) | 2016-10-12 |
Family
ID=47357436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014515934A Active JP6005736B2 (ja) | 2011-06-13 | 2012-06-13 | Ｉｌ−１２を用いる皮膚損傷の軽減 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9925246B2 (enExample) |
| EP (1) | EP2718456B1 (enExample) |
| JP (1) | JP6005736B2 (enExample) |
| CA (1) | CA2839261A1 (enExample) |
| WO (1) | WO2012174056A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109789187A (zh) * | 2016-07-18 | 2019-05-21 | 创新疗法医药有限公司 | Il-12作为替代免疫治疗剂的用途 |
| JP7045671B2 (ja) * | 2018-11-12 | 2022-04-01 | 有限会社バイオ研 | 皮膚塗布用の皮膚創傷治癒促進組成物、その製造方法、及び創傷被覆材 |
| JP7448137B2 (ja) * | 2020-03-10 | 2024-03-12 | 日本ゼトック株式会社 | アクチン重合促進剤 |
| JP2024529315A (ja) * | 2021-07-30 | 2024-08-06 | ザ ボード オブ トラスティス オブ ザ リーランド スタンフォード ジュニア ユニヴァーシティー | 皮膚移植方法におけるメカノトランスダクション破壊媒介及びその実施における使用のための組成物 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| DE3675588D1 (de) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| US5457038A (en) | 1988-11-10 | 1995-10-10 | Genetics Institute, Inc. | Natural killer stimulatory factor |
| US6683046B1 (en) | 1989-12-22 | 2004-01-27 | Hoffmann-La Roche Inc. | Purification and characterization of cytotoxic lymphocyte maturation factor and monoclonal antibodies thereto |
| US5573764A (en) | 1994-01-21 | 1996-11-12 | Genetics Institute, Inc. | Use of interleukin-12 to prevent graft versus host disease |
| JP2000510813A (ja) | 1995-02-06 | 2000-08-22 | ジェネテイックス・インスティテュート・インコーポレイテッド | Ｉｌ−１２用処方 |
| US5853714A (en) | 1995-03-27 | 1998-12-29 | Genetics Institute, Inc. | Method for purification of IL-12 |
| US6423308B1 (en) * | 1998-09-15 | 2002-07-23 | Wyeth | Treatment of Kaposi's sarcoma with IL-12 |
| US7052685B1 (en) * | 1998-10-15 | 2006-05-30 | Trustees Of The University Of Pennsylvania | Methods for treatment of cutaneous T-cell lymphoma |
| PT1463751E (pt) * | 2001-12-21 | 2013-08-26 | Human Genome Sciences Inc | Proteínas de fusão de albumina |
| JP4902961B2 (ja) * | 2002-12-23 | 2012-03-21 | シェーリング コーポレイション | 哺乳動物サイトカインの用途；関連試薬 |
| US7763256B2 (en) * | 2002-12-23 | 2010-07-27 | William Marsh Rice University | Compositions and methods for suppressing fibrocytes and for detecting fibrocyte differentiation |
| US7939058B2 (en) * | 2003-07-03 | 2011-05-10 | University Of Southern California | Uses of IL-12 in hematopoiesis |
| WO2005007093A2 (en) | 2003-07-03 | 2005-01-27 | University Of Southern California | Uses of il-12 in hematopoiesis |
| PL1793859T3 (pl) | 2004-08-20 | 2009-08-31 | Smithkline Beecham Corp | Leczenie zapalenia śluzówki jamy ustnej i jelit przez podawanie ludzkiej IL-18 |
| WO2008067042A2 (en) * | 2006-10-10 | 2008-06-05 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Modeling wound healing |
| US20100330046A1 (en) * | 2009-05-21 | 2010-12-30 | Stratatech Corporation | Human skin substitutes expressing il-12 |
-
2012
- 2012-06-13 US US14/125,887 patent/US9925246B2/en active Active
- 2012-06-13 EP EP12801163.2A patent/EP2718456B1/en active Active
- 2012-06-13 WO PCT/US2012/042165 patent/WO2012174056A1/en not_active Ceased
- 2012-06-13 JP JP2014515934A patent/JP6005736B2/ja active Active
- 2012-06-13 CA CA2839261A patent/CA2839261A1/en not_active Abandoned
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