JP6005736B2 - Ｉｌ−１２を用いる皮膚損傷の軽減 - Google Patents

Ｉｌ−１２を用いる皮膚損傷の軽減 Download PDF

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Publication number
JP6005736B2
JP6005736B2 JP2014515934A JP2014515934A JP6005736B2 JP 6005736 B2 JP6005736 B2 JP 6005736B2 JP 2014515934 A JP2014515934 A JP 2014515934A JP 2014515934 A JP2014515934 A JP 2014515934A JP 6005736 B2 JP6005736 B2 JP 6005736B2
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wound
pharmaceutical composition
administration
skin
composition according
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Japanese (ja)
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JP2014517038A (ja
JP2014517038A5 (enExample
Inventor
バジーレ，レナ，エー．
エルフソン，ドルフ
ギャラハー，ティモシー，ケー．
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ニューメディシンズ，インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/208—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2014515934A 2011-06-13 2012-06-13 Ｉｌ−１２を用いる皮膚損傷の軽減 Active JP6005736B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161496472P 2011-06-13 2011-06-13
US61/496,472 2011-06-13
US201161528053P 2011-08-26 2011-08-26
US61/528,053 2011-08-26
PCT/US2012/042165 WO2012174056A1 (en) 2011-06-13 2012-06-13 Mitigation of cutaneous injury with il-12

Publications (3)

Publication Number Publication Date
JP2014517038A JP2014517038A (ja) 2014-07-17
JP2014517038A5 JP2014517038A5 (enExample) 2015-07-30
JP6005736B2 true JP6005736B2 (ja) 2016-10-12

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ID=47357436

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014515934A Active JP6005736B2 (ja) 2011-06-13 2012-06-13 Ｉｌ−１２を用いる皮膚損傷の軽減

Country Status (5)

Country Link
US (1) US9925246B2 (enExample)
EP (1) EP2718456B1 (enExample)
JP (1) JP6005736B2 (enExample)
CA (1) CA2839261A1 (enExample)
WO (1) WO2012174056A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3484500A4 (en) * 2016-07-18 2020-01-08 Neumedicines, Inc USE OF IL-12 AS A REPLACEMENT IMMUNOTHERAPEUTIC
JP7045671B2 (ja) * 2018-11-12 2022-04-01 有限会社バイオ研 皮膚塗布用の皮膚創傷治癒促進組成物、その製造方法、及び創傷被覆材
JP7448137B2 (ja) * 2020-03-10 2024-03-12 日本ゼトック株式会社 アクチン重合促進剤
CA3220398A1 (en) * 2021-07-30 2023-02-02 Geoffrey Gurtner Mechanotransduction disruption mediation in skin grafting methods and compositions for use in practicing the same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
EP0206448B1 (en) 1985-06-19 1990-11-14 Ajinomoto Co., Inc. Hemoglobin combined with a poly(alkylene oxide)
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US5457038A (en) 1988-11-10 1995-10-10 Genetics Institute, Inc. Natural killer stimulatory factor
US5780597A (en) 1989-12-22 1998-07-14 Hoffmann-La Roche Inc. Monoclonal antibodies to cytotoxic lymphocyte maturation factor
US5573764A (en) 1994-01-21 1996-11-12 Genetics Institute, Inc. Use of interleukin-12 to prevent graft versus host disease
JP2000510813A (ja) 1995-02-06 2000-08-22 ジェネテイックス・インスティテュート・インコーポレイテッド Ｉｌ−１２用処方
US5853714A (en) 1995-03-27 1998-12-29 Genetics Institute, Inc. Method for purification of IL-12
AU761520B2 (en) * 1998-09-15 2003-06-05 Genetics Institute, Llc Treatment of Kaposi's Sarcoma with IL-12
US7052685B1 (en) * 1998-10-15 2006-05-30 Trustees Of The University Of Pennsylvania Methods for treatment of cutaneous T-cell lymphoma
CA2841097A1 (en) 2001-12-21 2003-07-24 Human Genome Sciences, Inc. Albumin and g-csf fusion proteins
US7763256B2 (en) * 2002-12-23 2010-07-27 William Marsh Rice University Compositions and methods for suppressing fibrocytes and for detecting fibrocyte differentiation
AU2003303384A1 (en) * 2002-12-23 2004-07-22 Schering Corporation Uses of mammalian cytokine; related reagents
EP1641431B1 (en) * 2003-07-03 2018-01-10 University Of Southern California Uses of il-12 for reducing the toxicity of chemo- and/or radio-therapy
US7939058B2 (en) * 2003-07-03 2011-05-10 University Of Southern California Uses of IL-12 in hematopoiesis
ATE526057T1 (de) 2004-08-20 2011-10-15 Glaxosmithkline Llc Wundheilung durch verabreichung von menschlichem il-18
WO2008067042A2 (en) 2006-10-10 2008-06-05 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Modeling wound healing
US20100330046A1 (en) * 2009-05-21 2010-12-30 Stratatech Corporation Human skin substitutes expressing il-12

Also Published As

Publication number Publication date
EP2718456A4 (en) 2014-11-19
US20140205561A1 (en) 2014-07-24
EP2718456A1 (en) 2014-04-16
US9925246B2 (en) 2018-03-27
WO2012174056A1 (en) 2012-12-20
CA2839261A1 (en) 2012-12-20
JP2014517038A (ja) 2014-07-17
EP2718456B1 (en) 2019-04-24

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