JP2014516947A5 - - Google Patents

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Publication number
JP2014516947A5
JP2014516947A5 JP2014509331A JP2014509331A JP2014516947A5 JP 2014516947 A5 JP2014516947 A5 JP 2014516947A5 JP 2014509331 A JP2014509331 A JP 2014509331A JP 2014509331 A JP2014509331 A JP 2014509331A JP 2014516947 A5 JP2014516947 A5 JP 2014516947A5
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JP
Japan
Prior art keywords
carbon atoms
compound
enzyme
light
group
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Pending
Application number
JP2014509331A
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English (en)
Japanese (ja)
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JP2014516947A (ja
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Priority claimed from PCT/US2012/035732 external-priority patent/WO2012151142A2/en
Publication of JP2014516947A publication Critical patent/JP2014516947A/ja
Publication of JP2014516947A5 publication Critical patent/JP2014516947A5/ja
Pending legal-status Critical Current

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JP2014509331A 2011-05-03 2012-04-30 フラッシュ・グロー型の１，２−ジオキセタン Pending JP2014516947A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161482134P 2011-05-03 2011-05-03
US61/482,134 2011-05-03
PCT/US2012/035732 WO2012151142A2 (en) 2011-05-03 2012-04-30 Flash and glow 1,2-dioxetanes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016192667A Division JP6440265B2 (ja) 2011-05-03 2016-09-30 フラッシュ・グロー型の１，２−ジオキセタン

Publications (2)

Publication Number Publication Date
JP2014516947A JP2014516947A (ja) 2014-07-17
JP2014516947A5 true JP2014516947A5 (enExample) 2015-05-07

Family

ID=46085191

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014509331A Pending JP2014516947A (ja) 2011-05-03 2012-04-30 フラッシュ・グロー型の１，２−ジオキセタン
JP2016192667A Active JP6440265B2 (ja) 2011-05-03 2016-09-30 フラッシュ・グロー型の１，２−ジオキセタン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016192667A Active JP6440265B2 (ja) 2011-05-03 2016-09-30 フラッシュ・グロー型の１，２−ジオキセタン

Country Status (6)

Country Link
US (4) US20140154675A1 (enExample)
EP (1) EP2705031B1 (enExample)
JP (2) JP2014516947A (enExample)
KR (1) KR101960113B1 (enExample)
CN (1) CN103649069B (enExample)
WO (1) WO2012151142A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3211050A1 (en) * 2016-02-26 2017-08-30 Trinseo Europe GmbH Molded structures of polycarbonate based substrates over molded with silicone rubbers
WO2018049145A1 (en) 2016-09-09 2018-03-15 Calithera Biosciences, Inc. Ectonucleotidase inhibitors and methods of use thereof
CN110402249A (zh) 2016-12-22 2019-11-01 卡利泰拉生物科技公司 外核苷酸酶抑制剂及其使用方法
CN112888696B (zh) 2018-06-21 2024-04-16 德琪医疗有限公司 外核苷酸酶抑制剂及其使用方法
JP2022553424A (ja) * 2019-10-28 2022-12-22 ベックマン コールター， インコーポレイテッド 急速、高強度化学発光ジオキサン
WO2025160017A1 (en) * 2024-01-26 2025-07-31 Beckman Coulter, Inc. Assay methods using chemiluminescent dioxetane compounds

Family Cites Families (24)

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CA1340590C (en) 1986-07-24 1999-06-08 John C. Voyta Chemiluminescence enhancement
US5582980A (en) * 1989-07-17 1996-12-10 Tropix, Inc. Chemiluminescent 1,2-dioxetanes
US5538847A (en) * 1989-07-17 1996-07-23 Tropix, Inc. Chemiluminescent 1,2-dioxetanes
US4952707A (en) * 1988-06-30 1990-08-28 Tropix, Inc. Enzymatically-cleavable chemiluminescent fused polycyclic ring-containing 1,2-dioxetanes
US5326882A (en) * 1989-07-17 1994-07-05 Tropix, Inc. Chemiluminescent 3-(substituted Adamant-2'-Ylidene) 1,2-dioxetanes
US5994073A (en) 1990-08-30 1999-11-30 Tropix, Inc. Enhancement of chemiluminescent assays
US5547836A (en) 1990-08-30 1996-08-20 Tropix, Inc. Enhancement of chemiluminescent assays
US5603868A (en) * 1992-10-30 1997-02-18 Abbott Laboratories Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes
US5773628A (en) * 1994-11-14 1998-06-30 Tropix, Inc. 1,2-dioxetane compounds with haloalkoxy groups, methods preparation and use
EP0809804A4 (en) * 1995-02-13 1999-03-31 Tropix Inc CHEMOLUMINESCENCE ENERGY TRANSFER TEST
JPH08245615A (ja) * 1995-03-11 1996-09-24 Masakatsu Matsumoto １，２−ジオキセタン誘導体
JP3855033B2 (ja) * 1995-09-08 2006-12-06 高砂香料工業株式会社 光学活性３−ヒドロキシ−γ−ブチロラクトンの製造方法
US5679803A (en) * 1995-10-25 1997-10-21 Tropix, Inc. 1,2 chemiluminescent dioxetanes of improved performance
ATE221061T1 (de) * 1995-10-17 2002-08-15 Tropix Inc Chemilumineszente 1,2-dioxetane mit verbesserter leistung
CA2338883A1 (en) * 1998-07-28 2000-02-10 Tropix, Inc. Benzothiazole dioxetanes
US6660529B2 (en) * 1998-07-28 2003-12-09 Pe Corporation Heteroaryl substituted benzothiazole dioxetanes
IL141830A0 (en) * 1998-09-08 2002-03-10 Giri Brij P Chemiluminescent 1,2-dioxetane
US7416898B2 (en) * 2002-10-04 2008-08-26 Giri Brij P Chemiluminescent 1,2-dioxetanes
WO2006073424A2 (en) * 2004-04-14 2006-07-13 Giri Brij P New ultra-sensitive chemiluminescent substrates for enzymes and their conjugates
US20060079699A1 (en) * 2004-08-27 2006-04-13 Brooks Edwards Intermediate compounds and methods for synthesizing chemiluminescent dioxetane substrates
US20060216768A1 (en) * 2004-09-09 2006-09-28 Alison Sparks Dioxetane-nanoparticle assemblies for energy transfer detection systems, methods of making the assemblies, and methods of using the assemblies in bioassays
JP2010528294A (ja) * 2007-05-23 2010-08-19 アプライド バイオシステムズ リミテッド ライアビリティー カンパニー 活性化された化学発光基質からエネルギー受容体色素へのエネルギー転移により生体分子を検出するための試薬、キットおよび方法
WO2009139811A2 (en) * 2008-05-15 2009-11-19 Tianxin Wang Chemiluminescent methods and reagents for analyte detection
WO2010101839A2 (en) * 2009-03-02 2010-09-10 Life Technologies Corporation Chemiluminescent compositions, methods, assays and kits for oxidative enzymes

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