JP2014516702A5 - - Google Patents
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- Publication number
- JP2014516702A5 JP2014516702A5 JP2014511881A JP2014511881A JP2014516702A5 JP 2014516702 A5 JP2014516702 A5 JP 2014516702A5 JP 2014511881 A JP2014511881 A JP 2014511881A JP 2014511881 A JP2014511881 A JP 2014511881A JP 2014516702 A5 JP2014516702 A5 JP 2014516702A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically active
- active compound
- exendin
- peptide
- here
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 description 6
- 208000004476 Acute Coronary Syndrome Diseases 0.000 description 2
- 208000002249 Diabetes Complications Diseases 0.000 description 2
- 206010012689 Diabetic retinopathy Diseases 0.000 description 2
- 108010088406 Glucagon-Like Peptides Proteins 0.000 description 2
- JUFFVKRROAPVBI-PVOYSMBESA-N chembl1210015 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N[C@H]1[C@@H]([C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO[C@]3(O[C@@H](C[C@H](O)[C@H](O)CO)[C@H](NC(C)=O)[C@@H](O)C3)C(O)=O)O2)O)[C@@H](CO)O1)NC(C)=O)C(=O)NCC(=O)NCC(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 JUFFVKRROAPVBI-PVOYSMBESA-N 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 108010015174 exendin 3 Proteins 0.000 description 2
- LMHMJYMCGJNXRS-IOPUOMRJSA-N exendin-3 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CO)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@H](C)O)[C@H](C)O)C(C)C)C1=CC=CC=C1 LMHMJYMCGJNXRS-IOPUOMRJSA-N 0.000 description 2
- PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 1
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 108010041986 DNA Vaccines Proteins 0.000 description 1
- 206010012655 Diabetic complications Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 108010011459 Exenatide Proteins 0.000 description 1
- 101000976075 Homo sapiens Insulin Proteins 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 208000010378 Pulmonary Embolism Diseases 0.000 description 1
- 208000001435 Thromboembolism Diseases 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229960001519 exenatide Drugs 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004026 insulin derivative Substances 0.000 description 1
- 208000002780 macular degeneration Diseases 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11167534.4 | 2011-05-25 | ||
| EP11167534 | 2011-05-25 | ||
| PCT/EP2012/059752 WO2012160160A1 (en) | 2011-05-25 | 2012-05-24 | Medicament delivery device with dispense interface sensor and method controlling the device |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014516702A JP2014516702A (ja) | 2014-07-17 |
| JP2014516702A5 true JP2014516702A5 (enExample) | 2015-07-02 |
| JP6050331B2 JP6050331B2 (ja) | 2016-12-21 |
Family
ID=44856966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014511881A Expired - Fee Related JP6050331B2 (ja) | 2011-05-25 | 2012-05-24 | 投薬インターフェース・センサを有する薬剤送達デバイスおよびこのデバイスを制御する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9492616B2 (enExample) |
| EP (1) | EP2714147B1 (enExample) |
| JP (1) | JP6050331B2 (enExample) |
| CN (1) | CN103796696B (enExample) |
| DK (1) | DK2714147T3 (enExample) |
| WO (1) | WO2012160160A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8157769B2 (en) | 2009-09-15 | 2012-04-17 | Medimop Medical Projects Ltd. | Cartridge insertion assembly for drug delivery system |
| US9692829B2 (en) | 2012-12-03 | 2017-06-27 | Mylan Inc. | Medication delivery system and method |
| US20140155827A1 (en) | 2012-12-03 | 2014-06-05 | Mylan, Inc. | Medicament information system and method |
| US9643770B2 (en) | 2012-12-03 | 2017-05-09 | Mylan Inc. | System and method for medicament storage, dispensing, and administration |
| US9179260B2 (en) | 2012-12-03 | 2015-11-03 | Mylan Inc. | Medicament information system and method |
| EP3178505B1 (en) * | 2012-12-13 | 2018-05-02 | Panasonic Healthcare Holdings Co., Ltd. | Medicament injection device |
| ES2727524T3 (es) * | 2013-01-16 | 2019-10-16 | Bayer Pharma AG | Bloqueo para dispositivo de inyección de fármaco |
| CN104936639A (zh) * | 2013-01-29 | 2015-09-23 | 赛诺菲-安万特德国有限公司 | 电子模块和药物输送装置 |
| US10420922B2 (en) * | 2013-02-01 | 2019-09-24 | The Brigham And Women's Hospital, Inc. | Swellable adhesive needles |
| CN105025955B (zh) | 2013-03-08 | 2017-07-28 | 松下健康医疗控股株式会社 | 药剂注入装置 |
| CA2928557C (en) | 2013-10-24 | 2023-10-10 | Trustees Of Boston University | Infusion system for preventing mischanneling of multiple medicaments |
| GB2525149A (en) * | 2014-01-30 | 2015-10-21 | Cellnovo Ltd | Therapeutic product delivery device |
| US10441717B2 (en) | 2014-04-15 | 2019-10-15 | Insulet Corporation | Monitoring a physiological parameter associated with tissue of a host to confirm delivery of medication |
| MX387194B (es) * | 2014-06-03 | 2025-03-18 | Amgen Inc | Sistemas y metodos para procesar de manera remota datos recolectados por un dispositivo de suministro de farmaco. |
| EP3261692B1 (en) | 2015-02-27 | 2020-08-19 | Novo Nordisk A/S | Accessory device with mounting safety feature |
| EP4252798A3 (en) | 2015-06-04 | 2023-10-25 | Medimop Medical Projects Ltd. | Cartridge insertion for drug delivery device |
| WO2017087888A1 (en) | 2015-11-18 | 2017-05-26 | President And Fellows Of Harvard College | Systems and methods for monitoring, managing, and treating asthma and anaphylaxis |
| US11179524B2 (en) | 2015-12-30 | 2021-11-23 | Ascendis Pharma A/S | Auto injector with detection of used cartridge and associated method |
| HUE059907T2 (hu) | 2015-12-30 | 2023-01-28 | Ascendis Pharma As | Patronrögzítõ rendszerrel ellátott automata befecskendezõ eszköz |
| SI3912660T1 (sl) * | 2015-12-30 | 2025-05-30 | Ascendis Pharma A/S | Avto injektor s prilagodljivim mehanizmom za izpihovanje zraka |
| US11406760B2 (en) | 2015-12-30 | 2022-08-09 | Ascendis Pharma A/S | Auto injector with charger safety |
| US11351305B2 (en) * | 2015-12-30 | 2022-06-07 | Ascendis Pharma A/S | Auto injector with temperature control |
| GB201600229D0 (en) * | 2016-01-06 | 2016-02-17 | Vicentra B V | Fluid delivery system |
| EP3419697B1 (en) * | 2016-02-26 | 2024-05-01 | Eli Lilly and Company | Reusable medication delivery device with remaining medication determination capability |
| EP3463520B1 (en) * | 2016-05-30 | 2024-01-24 | Novo Nordisk A/S | Mounting feature for accessory device |
| CN109152884B (zh) | 2016-05-30 | 2022-02-11 | 诺和诺德股份有限公司 | 具有零位置调节特征的药物输送装置 |
| CN109310831B (zh) | 2016-06-02 | 2021-11-23 | 西医药服务以色列有限公司 | 三位置针缩回 |
| EP3490635B1 (en) * | 2016-08-01 | 2021-11-17 | West Pharma. Services Il, Ltd. | Partial door closure prevention spring |
| US11684724B2 (en) | 2017-05-23 | 2023-06-27 | Ascendis Pharma A/S | Auto injector with variable plunger force |
| JP6921997B2 (ja) | 2017-05-30 | 2021-08-18 | ウェスト ファーマ サービシーズ イスラエル リミテッド | ウェアラブル注射器のモジュラ駆動トレイン |
| CN110809484B (zh) * | 2017-06-29 | 2022-07-12 | 阿森迪斯药物股份有限公司 | 具有重构处理支承件的自动注射器 |
| WO2019032375A1 (en) | 2017-08-10 | 2019-02-14 | West Pharma, Services Il, Ltd. | INJECTOR AUTO-TEST AND INJECTOR DOOR UNLOCKING MECHANISM ACTING IN RESPONSE AUTO-TEST AUDIT |
| JP7747438B2 (ja) * | 2017-11-16 | 2025-10-01 | アムジエン・インコーポレーテツド | 失速及び終点検出を有するオートインジェクタ |
| WO2019126421A1 (en) | 2017-12-22 | 2019-06-27 | West Pharma. Services Il., Ltd. | Injector usable with different dimension cartridges |
| US11241532B2 (en) | 2018-08-29 | 2022-02-08 | Insulet Corporation | Drug delivery system with sensor having optimized communication and infusion site |
| US20220339357A1 (en) * | 2019-09-09 | 2022-10-27 | Yunling Hao | Injection device |
| CN110548201B (zh) * | 2019-09-09 | 2025-02-21 | 郝云玲 | 一种注射装置 |
| EP4221781A2 (en) | 2020-10-02 | 2023-08-09 | Insulet Corporation | Fluid delivery device having multiple penetrating elements |
| WO2022133218A1 (en) | 2020-12-18 | 2022-06-23 | Insulet Corporation | Adhesive pad with a metallic coil for securing an on-body medical device |
| EP4059547B1 (en) * | 2021-03-19 | 2025-10-08 | Ypsomed AG | Contact detection system for an injection device |
| EP4346945A1 (en) | 2021-05-28 | 2024-04-10 | Insulet Corporation | Spring-based status sensors |
| US12406760B2 (en) | 2021-06-07 | 2025-09-02 | Insulet Corporation | Exercise safety prediction based on physiological conditions |
| WO2024175400A1 (en) | 2023-02-24 | 2024-08-29 | Shl Medical Ag | A power unit of a medicament delivery device |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1225023A (zh) * | 1996-07-05 | 1999-08-04 | 诺沃挪第克公司 | 剂量设定装置 |
| BR9710207A (pt) | 1996-07-05 | 1999-11-09 | Novo Nordisk As | Dispositivo para administracao de drogas. |
| US5993412A (en) * | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
| US7621893B2 (en) * | 1998-10-29 | 2009-11-24 | Medtronic Minimed, Inc. | Methods and apparatuses for detecting occlusions in an ambulatory infusion pump |
| US7766873B2 (en) * | 1998-10-29 | 2010-08-03 | Medtronic Minimed, Inc. | Method and apparatus for detecting occlusions in an ambulatory infusion pump |
| JP3845857B2 (ja) * | 2001-03-15 | 2006-11-15 | ニプロ株式会社 | 簡易薬液注入器 |
| US7033338B2 (en) * | 2002-02-28 | 2006-04-25 | Smiths Medical Md, Inc. | Cartridge and rod for axially loading medication pump |
| JP5089991B2 (ja) * | 2004-02-18 | 2012-12-05 | アレス トレイディング ソシエテ アノニム | 液状薬剤を注射する手持ち型電子制御式注射器械 |
| ATE468142T1 (de) * | 2004-03-31 | 2010-06-15 | Lilly Co Eli | Injektionsgerät mit einer nadelkassette zur abgabe einer pharmazeutischen flüssigkeit |
| KR100763050B1 (ko) * | 2004-03-31 | 2007-10-04 | 일라이 릴리 앤드 캄파니 | 액체 약품을 전달하기 위한 니들 카세트를 갖는 주입 장치 |
| EP1962947A4 (en) * | 2005-12-20 | 2017-06-28 | Antares Pharma, Inc. | Needle-free injection device |
| US7967785B2 (en) | 2008-07-14 | 2011-06-28 | Nipro Healthcare Systems, Llc | Insulin reservoir detection via magnetic switching |
| TW201200190A (en) * | 2010-03-26 | 2012-01-01 | Sanofi Aventis Deutschland | Electro-mechanical drug delivery device |
| CN103338800B (zh) * | 2010-11-29 | 2015-07-01 | 赛诺菲-安万特德国有限公司 | 用于药物输送装置的分配接口部件 |
-
2012
- 2012-05-24 EP EP12723204.9A patent/EP2714147B1/en active Active
- 2012-05-24 DK DK12723204.9T patent/DK2714147T3/en active
- 2012-05-24 JP JP2014511881A patent/JP6050331B2/ja not_active Expired - Fee Related
- 2012-05-24 US US14/119,211 patent/US9492616B2/en active Active
- 2012-05-24 CN CN201280037234.2A patent/CN103796696B/zh not_active Expired - Fee Related
- 2012-05-24 WO PCT/EP2012/059752 patent/WO2012160160A1/en not_active Ceased