JP2014512820A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014512820A5 JP2014512820A5 JP2014508162A JP2014508162A JP2014512820A5 JP 2014512820 A5 JP2014512820 A5 JP 2014512820A5 JP 2014508162 A JP2014508162 A JP 2014508162A JP 2014508162 A JP2014508162 A JP 2014508162A JP 2014512820 A5 JP2014512820 A5 JP 2014512820A5
- Authority
- JP
- Japan
- Prior art keywords
- stem cells
- substrate
- period
- seeded
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 23
- 210000000130 stem cell Anatomy 0.000 claims 17
- 239000000758 substrate Substances 0.000 claims 14
- 210000004027 cell Anatomy 0.000 claims 4
- 102000018233 Fibroblast Growth Factor Human genes 0.000 claims 3
- 108050007372 Fibroblast Growth Factor Proteins 0.000 claims 3
- 239000011248 coating agent Substances 0.000 claims 3
- 238000000576 coating method Methods 0.000 claims 3
- 238000005138 cryopreservation Methods 0.000 claims 3
- 229940126864 fibroblast growth factor Drugs 0.000 claims 3
- 230000035899 viability Effects 0.000 claims 3
- 238000010438 heat treatment Methods 0.000 claims 2
- VRBFTYUMFJWSJY-UHFFFAOYSA-N 28804-46-8 Chemical compound ClC1CC(C=C2)=CC=C2C(Cl)CC2=CC=C1C=C2 VRBFTYUMFJWSJY-UHFFFAOYSA-N 0.000 claims 1
- 102100035140 Vitronectin Human genes 0.000 claims 1
- 108010031318 Vitronectin Proteins 0.000 claims 1
- 210000004504 adult stem cell Anatomy 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 230000008602 contraction Effects 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 210000004263 induced pluripotent stem cell Anatomy 0.000 claims 1
- 108010082117 matrigel Proteins 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 claims 1
- 229920000052 poly(p-xylylene) Polymers 0.000 claims 1
- 108010056030 retronectin Proteins 0.000 claims 1
- 239000002356 single layer Substances 0.000 claims 1
- 239000013589 supplement Substances 0.000 claims 1
- 238000010257 thawing Methods 0.000 claims 1
- 210000001578 tight junction Anatomy 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- 239000002699 waste material Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161481015P | 2011-04-29 | 2011-04-29 | |
| US61/481,015 | 2011-04-29 | ||
| PCT/US2012/035676 WO2012149484A2 (en) | 2011-04-29 | 2012-04-27 | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017036933A Division JP2017184724A (ja) | 2011-04-29 | 2017-02-28 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014512820A JP2014512820A (ja) | 2014-05-29 |
| JP2014512820A5 true JP2014512820A5 (cg-RX-API-DMAC7.html) | 2015-06-18 |
| JP6200883B2 JP6200883B2 (ja) | 2017-09-20 |
Family
ID=47073114
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014508162A Active JP6200883B2 (ja) | 2011-04-29 | 2012-04-27 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
| JP2017036933A Pending JP2017184724A (ja) | 2011-04-29 | 2017-02-28 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017036933A Pending JP2017184724A (ja) | 2011-04-29 | 2017-02-28 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10470457B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2702135B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6200883B2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2722207T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012149484A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| SG10201912182UA (en) | 2004-01-23 | 2020-02-27 | Astellas Inst For Regenerative Medicine | Improved modalities for the treatment of degenerative diseases of the retina |
| CA3177952A1 (en) | 2007-10-12 | 2009-04-23 | Astellas Institute For Regenerative Medicine | Improved methods of producing rpe cells and compositions of rpe cells |
| WO2011063005A2 (en) | 2009-11-17 | 2011-05-26 | Advanced Cell Technology, Inc. | Methods of producing human rpe cells and pharmaceutical preparations of human rpe cells |
| EP3549617B1 (en) | 2010-07-12 | 2023-09-13 | University of Southern California | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| WO2012149484A2 (en) * | 2011-04-29 | 2012-11-01 | University Of Southern California | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
| US10478206B2 (en) | 2011-04-29 | 2019-11-19 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| HUE044778T2 (hu) * | 2011-11-14 | 2019-11-28 | Astellas Inst For Regenerative Medicine | Humán RPE sejt gyógyászati készítmények és alkalmazásaik |
| US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
| AU2014212230B2 (en) | 2013-02-01 | 2019-07-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for generating retinal pigment epithelium (RPE) cells from induced pluripotent stem cells (iPSCs) |
| US9977012B2 (en) | 2014-10-24 | 2018-05-22 | Lifeline Scientific, Inc. | Select on of extracellular matrix components and or matricellular proteins for improved post-cryopreservation cell viability and retention |
| IL273405B2 (en) | 2014-12-30 | 2024-01-01 | Cell Cure Neurosciences Ltd | Rpe cell populations and methods of generating same |
| AU2016321170B2 (en) | 2015-09-08 | 2022-09-01 | Fujifilm Cellular Dynamics | Method for reproducible differentiation of clinical-grade retinal pigment epithelium cells |
| CN108291206B (zh) | 2015-09-08 | 2022-07-08 | 富士胶片细胞动力公司 | 干细胞来源的视网膜色素上皮的基于macs的纯化 |
| TWI670371B (zh) | 2016-10-04 | 2019-09-01 | 全崴生技股份有限公司 | 用於細胞冷凍保存的組成物和方法 |
| CN111741735A (zh) * | 2017-12-29 | 2020-10-02 | 细胞治疗神经科学有限公司 | 视网膜色素上皮细胞组合物 |
| CN109988750A (zh) * | 2017-12-29 | 2019-07-09 | 江苏艾尔康生物医药科技有限公司 | 一种视网膜色素上皮细胞的培养方法 |
| CA3110114A1 (en) * | 2018-08-22 | 2020-02-27 | The Governors Of The University Of Alberta | Cryopreservation of cell monolayers |
| SG11202102140WA (en) | 2018-09-07 | 2021-04-29 | Univ Southern California | Cryopreservation of cell-seeded substrates and related methods |
| KR20210095885A (ko) | 2018-11-19 | 2021-08-03 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | 생분해성 조직 대체 임플란트 및 그의 용도 |
| CN114144514B (zh) | 2019-05-09 | 2025-11-25 | 富士胶片细胞动力公司 | 产生肝细胞的方法 |
| WO2021045122A1 (ja) * | 2019-09-02 | 2021-03-11 | 株式会社ニチレイバイオサイエンス | 網膜色素上皮細胞の三次元組織集合物の凍結体を製造する方法 |
| CA3180561A1 (en) | 2020-05-29 | 2021-12-02 | Andrew DIAS | Bilayer of retinal pigmented epithelium and photoreceptors and use thereof |
| CN117881777A (zh) | 2021-05-26 | 2024-04-12 | 富士胶片细胞动力公司 | 防止多能干细胞中基因快速沉默的方法 |
| EP4346928A1 (en) | 2021-05-28 | 2024-04-10 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Biodegradable tissue scaffold with secondary matrix to host weakly adherent cells |
| WO2022251499A1 (en) | 2021-05-28 | 2022-12-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods to generate macular, central and peripheral retinal pigment epithelial cells |
| US20220386591A1 (en) * | 2021-06-04 | 2022-12-08 | The Secant Group Llc | Cryopreservation compositions and methods including glycerol ester components |
| AU2022376962A1 (en) | 2021-10-29 | 2024-04-18 | FUJIFILM Cellular Dynamics, Inc. | Dopaminergic neurons comprising mutations and methods of use thereof |
| US20240003871A1 (en) | 2022-06-29 | 2024-01-04 | FUJIFILM Cellular Dynamics, Inc. | Ipsc-derived astrocytes and methods of use thereof |
| US20240269189A1 (en) | 2022-12-19 | 2024-08-15 | FUJIFILM Holdings America Corporation | Extracellular vesicle-enriched secretome composition derived from induced pluripotent stem cell derived-microglia and methods of use thereof |
| US20250362218A1 (en) | 2024-05-21 | 2025-11-27 | FUJIFILM Cellular Dynamics, Inc. | Particle counting and biomass measurements of aggregated cell compositions |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4163828A (en) | 1978-01-20 | 1979-08-07 | Union Carbide Corporation | Parylene stabilization |
| JP2003047464A (ja) * | 2001-08-02 | 2003-02-18 | Institute Of Tsukuba Liaison Co Ltd | 動物細胞の保存方法 |
| US20030054331A1 (en) * | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
| US20050106554A1 (en) * | 2003-11-19 | 2005-05-19 | Palecek Sean P. | Cryopreservation of pluripotent stem cells |
| US7691626B2 (en) * | 2003-11-21 | 2010-04-06 | The Regents Of The University Of California | Self-contained cell culture apparatus and method of use |
| US20060063141A1 (en) | 2004-09-17 | 2006-03-23 | Mcgann Locksley E | Method of cryopreserving cells |
| KR101368924B1 (ko) * | 2005-11-17 | 2014-03-04 | 니뽄젠야쿠코교 가부시키가이샤 | 세포 보존용 수용액 |
| JP2007306856A (ja) * | 2006-05-18 | 2007-11-29 | Japan Health Science Foundation | 細胞凍結保存方法 |
| US7923823B2 (en) | 2007-01-23 | 2011-04-12 | Infineon Technologies Ag | Semiconductor device with parylene coating |
| US20090123992A1 (en) * | 2007-11-12 | 2009-05-14 | Milton Chin | Shape-Shifting Vitrification Device |
| EP3338549A1 (en) * | 2007-11-20 | 2018-06-27 | Pioneer Surgical Orthobiologics, Inc. | Cryopreservation of cells using cross-linked bioactive hydrogel matrix particles |
| EP3549617B1 (en) * | 2010-07-12 | 2023-09-13 | University of Southern California | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| US20140045264A1 (en) | 2011-04-29 | 2014-02-13 | University Of Southern California | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| WO2012149484A2 (en) | 2011-04-29 | 2012-11-01 | University Of Southern California | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
| CA2792081C (en) | 2011-10-11 | 2020-10-27 | Bond University Ltd | Layered compositions comprising 3d nanofibre webbing for tissue repair |
| AU2014212230B2 (en) | 2013-02-01 | 2019-07-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for generating retinal pigment epithelium (RPE) cells from induced pluripotent stem cells (iPSCs) |
| DE112014005168B4 (de) | 2013-12-13 | 2018-05-24 | Panasonic Intellectual Property Management Co., Ltd. | Toilettensitzvorrichtung und Toilettenschüsselvorrichtung |
| CN108291206B (zh) | 2015-09-08 | 2022-07-08 | 富士胶片细胞动力公司 | 干细胞来源的视网膜色素上皮的基于macs的纯化 |
-
2012
- 2012-04-27 WO PCT/US2012/035676 patent/WO2012149484A2/en not_active Ceased
- 2012-04-27 ES ES12776772T patent/ES2722207T3/es active Active
- 2012-04-27 EP EP12776772.1A patent/EP2702135B1/en active Active
- 2012-04-27 JP JP2014508162A patent/JP6200883B2/ja active Active
-
2017
- 2017-01-27 US US15/418,099 patent/US10470457B2/en active Active
- 2017-02-28 JP JP2017036933A patent/JP2017184724A/ja active Pending
-
2019
- 2019-10-21 US US16/658,457 patent/US11533908B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014512820A5 (cg-RX-API-DMAC7.html) | ||
| JP2013532492A5 (cg-RX-API-DMAC7.html) | ||
| Shafiq et al. | Insight on stem cell preconditioning and instructive biomaterials to enhance cell adhesion, retention, and engraftment for tissue repair | |
| Wang et al. | Defined and scalable generation of hepatocyte-like cells from human pluripotent stem cells | |
| WO2009115581A3 (en) | Improved cryopreservation of adipose tissue for the isolation of mesenchymal stem cells | |
| JP2008501320A5 (cg-RX-API-DMAC7.html) | ||
| JP2015516161A5 (cg-RX-API-DMAC7.html) | ||
| ES2722207T3 (es) | Procedimientos para la crioconservación de células epiteliales de pigmento retiniano derivadas de citoblastos crecidas sobre un sustrato polimérico | |
| JP2011206064A5 (cg-RX-API-DMAC7.html) | ||
| WO2011143299A3 (en) | Differentiation of human embryonic stem cells | |
| MX2013003856A (es) | Inserto de cultivo celular. | |
| HK1217110A1 (zh) | 在空氣-液體界面處培養人胚胎幹細胞以用於分化成胰腺內分泌細胞 | |
| JP2017532954A5 (cg-RX-API-DMAC7.html) | ||
| MX352758B (es) | Metodos mejorados para preparar escualeno. | |
| WO2011114237A3 (en) | Composition and method for enabling proliferation of pluripotent human stem cells | |
| WO2007042225A3 (en) | A method for obtaining a xeno-free hbs cell line | |
| JP2015522281A5 (cg-RX-API-DMAC7.html) | ||
| SG133482A1 (en) | Repair method for propagating epitaxial crystalline structures | |
| Lushchak et al. | Intermittent fasting | |
| JP2013226127A5 (cg-RX-API-DMAC7.html) | ||
| Cha et al. | Improving the survival and maintenance of the undifferentiated state of cryopreserved human embryonic stem cells by extended incubation with feeder cells overnight before vitrification | |
| Seo et al. | Current progress and prospects of reprogramming factors-stem cells vs germ cells | |
| Jiang et al. | Cultivation and induction of fetal liver cells in poly-L-lactic acid scaffold | |
| Grizay et al. | Transplantation of cryopreserved fetal liver cells seeded into macroporous alginate-gelatin scaffolds in rats with liver failure | |
| WO2013110730A3 (en) | Heat storage system |