JP2014512820A5 - - Google Patents
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- Publication number
- JP2014512820A5 JP2014512820A5 JP2014508162A JP2014508162A JP2014512820A5 JP 2014512820 A5 JP2014512820 A5 JP 2014512820A5 JP 2014508162 A JP2014508162 A JP 2014508162A JP 2014508162 A JP2014508162 A JP 2014508162A JP 2014512820 A5 JP2014512820 A5 JP 2014512820A5
- Authority
- JP
- Japan
- Prior art keywords
- stem cells
- substrate
- period
- seeded
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000000034 method Methods 0.000 claims 23
- 210000000130 stem cell Anatomy 0.000 claims 17
- 239000000758 substrate Substances 0.000 claims 14
- 210000004027 cell Anatomy 0.000 claims 4
- 102000018233 Fibroblast Growth Factor Human genes 0.000 claims 3
- 108050007372 Fibroblast Growth Factor Proteins 0.000 claims 3
- 239000011248 coating agent Substances 0.000 claims 3
- 238000000576 coating method Methods 0.000 claims 3
- 238000005138 cryopreservation Methods 0.000 claims 3
- 229940126864 fibroblast growth factor Drugs 0.000 claims 3
- 230000035899 viability Effects 0.000 claims 3
- 238000010438 heat treatment Methods 0.000 claims 2
- VRBFTYUMFJWSJY-UHFFFAOYSA-N 28804-46-8 Chemical compound ClC1CC(C=C2)=CC=C2C(Cl)CC2=CC=C1C=C2 VRBFTYUMFJWSJY-UHFFFAOYSA-N 0.000 claims 1
- 102100035140 Vitronectin Human genes 0.000 claims 1
- 108010031318 Vitronectin Proteins 0.000 claims 1
- 210000004504 adult stem cell Anatomy 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 230000008602 contraction Effects 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 210000004263 induced pluripotent stem cell Anatomy 0.000 claims 1
- 108010082117 matrigel Proteins 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 claims 1
- 229920000052 poly(p-xylylene) Polymers 0.000 claims 1
- 108010056030 retronectin Proteins 0.000 claims 1
- 239000002356 single layer Substances 0.000 claims 1
- 239000013589 supplement Substances 0.000 claims 1
- 238000010257 thawing Methods 0.000 claims 1
- 210000001578 tight junction Anatomy 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- 239000002699 waste material Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161481015P | 2011-04-29 | 2011-04-29 | |
| US61/481,015 | 2011-04-29 | ||
| PCT/US2012/035676 WO2012149484A2 (en) | 2011-04-29 | 2012-04-27 | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017036933A Division JP2017184724A (ja) | 2011-04-29 | 2017-02-28 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014512820A JP2014512820A (ja) | 2014-05-29 |
| JP2014512820A5 true JP2014512820A5 (cg-RX-API-DMAC10.html) | 2015-06-18 |
| JP6200883B2 JP6200883B2 (ja) | 2017-09-20 |
Family
ID=47073114
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014508162A Active JP6200883B2 (ja) | 2011-04-29 | 2012-04-27 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
| JP2017036933A Pending JP2017184724A (ja) | 2011-04-29 | 2017-02-28 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017036933A Pending JP2017184724A (ja) | 2011-04-29 | 2017-02-28 | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10470457B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2702135B1 (cg-RX-API-DMAC10.html) |
| JP (2) | JP6200883B2 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2722207T3 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2012149484A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| CA2937099A1 (en) | 2004-01-23 | 2005-08-04 | Astellas Institute For Regenerative Medicine | Improved modalities for the treatment of degenerative diseases of the retina |
| EP2209888B1 (en) | 2007-10-12 | 2019-12-04 | Astellas Institute for Regenerative Medicine | Improved methods of producing rpe cells and compositions of rpe cells |
| IL281453B (en) | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
| AU2011279250B2 (en) | 2010-07-12 | 2014-12-04 | California Institute Of Technology | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| EP2702135B1 (en) * | 2011-04-29 | 2019-04-17 | University of Southern California | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
| WO2012149468A2 (en) | 2011-04-29 | 2012-11-01 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| IL287381B2 (en) * | 2011-11-14 | 2024-04-01 | Astellas Inst For Regenerative Medicine | Pharmaceutical preparations of human rpe cells and uses thereof |
| US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
| DK2951290T3 (en) | 2013-02-01 | 2018-01-22 | Us Health | PROCEDURE FOR PREPARING RETINAL PIGMENTAL EPIT (RPE) CELLS FROM INDUCED PLURIPOTENT STEM CELLS (IPSCS) |
| US9977012B2 (en) * | 2014-10-24 | 2018-05-22 | Lifeline Scientific, Inc. | Select on of extracellular matrix components and or matricellular proteins for improved post-cryopreservation cell viability and retention |
| AU2015373050B2 (en) | 2014-12-30 | 2022-09-29 | Cell Cure Neurosciences Ltd. | RPE cell populations and methods of generating same |
| CN114807035B (zh) | 2015-09-08 | 2024-02-02 | (由卫生与公众服务部部长代表的)美利坚合众国 | 临床级别视网膜色素上皮细胞的可再现的分化方法 |
| US11162070B2 (en) | 2015-09-08 | 2021-11-02 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
| US10815456B2 (en) | 2016-10-04 | 2020-10-27 | Transwell Biotech Co., Ltd. | Composition, kit and method for cryopreserving cells |
| BR112020013238A2 (pt) | 2017-12-29 | 2020-12-01 | Cell Cure Neurosciences Ltd. | composição e método para formular células do epitélio pigmentar da retina bem como uso da dita composição para tratar uma condição retiniana |
| CN109988750A (zh) * | 2017-12-29 | 2019-07-09 | 江苏艾尔康生物医药科技有限公司 | 一种视网膜色素上皮细胞的培养方法 |
| WO2020037416A1 (en) * | 2018-08-22 | 2020-02-27 | The Governors Of The University Of Alberta | Cryopreservation of cell monolayers |
| KR20250058061A (ko) * | 2018-09-07 | 2025-04-29 | 유니버시티 오브 써던 캘리포니아 | 세포 시딩된 기질로부터의 치료적 상층액 및 관련 방법 |
| CA3119041A1 (en) | 2018-11-19 | 2020-05-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Biodegradable tissue replacement implant and its use |
| EP3966315A1 (en) | 2019-05-09 | 2022-03-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of hepatocytes |
| US20220295782A1 (en) * | 2019-09-02 | 2022-09-22 | Nichirei Bioscience Inc. | Method for producing frozen body of three-dimensional tissue aggregate of retinal pigment epithelial cells |
| IL298254A (en) | 2020-05-29 | 2023-01-01 | Fujifilm Cellular Dynamics Inc | Double layer of retinal pigment epithelium and photoreceptors and their uses |
| WO2022251443A1 (en) | 2021-05-26 | 2022-12-01 | FUJIFILM Cellular Dynamics, Inc. | Methods to prevent rapid silencing of genes in pluripotent stem cells |
| JP2024520423A (ja) | 2021-05-28 | 2024-05-24 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 弱接着細胞を収容するための二次マトリックスを有する生分解性組織スキャフォールド |
| WO2022251499A1 (en) | 2021-05-28 | 2022-12-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods to generate macular, central and peripheral retinal pigment epithelial cells |
| WO2022256502A1 (en) * | 2021-06-04 | 2022-12-08 | The Secant Group Llc | Cryopreservation compositions and methods including glycerol ester components |
| AU2022376962A1 (en) | 2021-10-29 | 2024-04-18 | FUJIFILM Cellular Dynamics, Inc. | Dopaminergic neurons comprising mutations and methods of use thereof |
| US20240003871A1 (en) | 2022-06-29 | 2024-01-04 | FUJIFILM Cellular Dynamics, Inc. | Ipsc-derived astrocytes and methods of use thereof |
| US20240269189A1 (en) | 2022-12-19 | 2024-08-15 | FUJIFILM Holdings America Corporation | Extracellular vesicle-enriched secretome composition derived from induced pluripotent stem cell derived-microglia and methods of use thereof |
| WO2025245202A1 (en) | 2024-05-21 | 2025-11-27 | FUJIFILM Cellular Dynamics, Inc. | Particle counting and biomass measurements of aggregated cell compositions |
| US20260146229A1 (en) | 2024-11-27 | 2026-05-28 | Bluerock Therapeutics Lp | Photoreceptor precursor cell (prp) compositions and uses thereof |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4163828A (en) | 1978-01-20 | 1979-08-07 | Union Carbide Corporation | Parylene stabilization |
| JP2003047464A (ja) * | 2001-08-02 | 2003-02-18 | Institute Of Tsukuba Liaison Co Ltd | 動物細胞の保存方法 |
| US20030054331A1 (en) * | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
| WO2005052138A1 (en) * | 2003-11-19 | 2005-06-09 | Wisconsin Alumni Research Foundation | Cryopreservation of pluripotent stem cells |
| WO2005069766A2 (en) * | 2003-11-21 | 2005-08-04 | The Regents Of The University Of California | Self-contained cell culture apparatus and method of use |
| US20060063141A1 (en) | 2004-09-17 | 2006-03-23 | Mcgann Locksley E | Method of cryopreserving cells |
| KR20140014318A (ko) * | 2005-11-17 | 2014-02-05 | 니뽄젠야쿠코교 가부시키가이샤 | 세포 보존용 수용액 |
| JP2007306856A (ja) * | 2006-05-18 | 2007-11-29 | Japan Health Science Foundation | 細胞凍結保存方法 |
| US7923823B2 (en) | 2007-01-23 | 2011-04-12 | Infineon Technologies Ag | Semiconductor device with parylene coating |
| US20090123992A1 (en) * | 2007-11-12 | 2009-05-14 | Milton Chin | Shape-Shifting Vitrification Device |
| EP3338549A1 (en) * | 2007-11-20 | 2018-06-27 | Pioneer Surgical Orthobiologics, Inc. | Cryopreservation of cells using cross-linked bioactive hydrogel matrix particles |
| AU2011279250B2 (en) * | 2010-07-12 | 2014-12-04 | California Institute Of Technology | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| EP2702135B1 (en) | 2011-04-29 | 2019-04-17 | University of Southern California | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
| US9414706B2 (en) | 2011-04-29 | 2016-08-16 | David Scott Purcell | Glove dispensing apparatus and glove cartridge for use therewith and glove dispensing method |
| CA2792081C (en) | 2011-10-11 | 2020-10-27 | Bond University Ltd | Layered compositions comprising 3d nanofibre webbing for tissue repair |
| DK2951290T3 (en) | 2013-02-01 | 2018-01-22 | Us Health | PROCEDURE FOR PREPARING RETINAL PIGMENTAL EPIT (RPE) CELLS FROM INDUCED PLURIPOTENT STEM CELLS (IPSCS) |
| JP6176336B2 (ja) | 2013-12-13 | 2017-08-09 | パナソニックＩｐマネジメント株式会社 | 便座装置、および便器装置 |
| US11162070B2 (en) | 2015-09-08 | 2021-11-02 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
-
2012
- 2012-04-27 EP EP12776772.1A patent/EP2702135B1/en active Active
- 2012-04-27 ES ES12776772T patent/ES2722207T3/es active Active
- 2012-04-27 JP JP2014508162A patent/JP6200883B2/ja active Active
- 2012-04-27 WO PCT/US2012/035676 patent/WO2012149484A2/en not_active Ceased
-
2017
- 2017-01-27 US US15/418,099 patent/US10470457B2/en active Active
- 2017-02-28 JP JP2017036933A patent/JP2017184724A/ja active Pending
-
2019
- 2019-10-21 US US16/658,457 patent/US11533908B2/en active Active
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