JP2008501320A5 - - Google Patents

Info

Publication number

JP2008501320A5

JP2008501320A5 JP2007513616A JP2007513616A JP2008501320A5 JP 2008501320 A5 JP2008501320 A5 JP 2008501320A5 JP 2007513616 A JP2007513616 A JP 2007513616A JP 2007513616 A JP2007513616 A JP 2007513616A JP 2008501320 A5 JP2008501320 A5 JP 2008501320A5

Authority

JP

Japan

Prior art keywords

cells

cell

temperature

cell suspension

thawed

Prior art date

2005-06-02

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 238000000034 method Methods 0.000 claims 41
• 210000004027 cell Anatomy 0.000 claims 34
• 239000006285 cell suspension Substances 0.000 claims 23
• 230000006910 ice nucleation Effects 0.000 claims 8
• 230000004913 activation Effects 0.000 claims 7
• 210000000130 stem cell Anatomy 0.000 claims 6
• 230000015572 biosynthetic process Effects 0.000 claims 3
• 210000002449 bone cell Anatomy 0.000 claims 3
• 238000001816 cooling Methods 0.000 claims 3
• 230000001413 cellular effect Effects 0.000 claims 2
• 239000002577 cryoprotective agent Substances 0.000 claims 2
• 230000003247 decreasing effect Effects 0.000 claims 2
• 230000018044 dehydration Effects 0.000 claims 2
• 238000006297 dehydration reaction Methods 0.000 claims 2
• 230000002526 effect on cardiovascular system Effects 0.000 claims 2
• 210000001671 embryonic stem cell Anatomy 0.000 claims 2
• 238000007710 freezing Methods 0.000 claims 2
• 230000008014 freezing Effects 0.000 claims 2
• 210000004602 germ cell Anatomy 0.000 claims 2
• 210000003494 hepatocyte Anatomy 0.000 claims 2
• 238000000338 in vitro Methods 0.000 claims 2
• 210000003292 kidney cell Anatomy 0.000 claims 2
• 239000003550 marker Substances 0.000 claims 2
• 210000004927 skin cell Anatomy 0.000 claims 2
• 238000011476 stem cell transplantation Methods 0.000 claims 2
• 238000010257 thawing Methods 0.000 claims 2
• 230000035899 viability Effects 0.000 claims 2
• LAQPKDLYOBZWBT-NYLDSJSYSA-N (2s,4s,5r,6r)-5-acetamido-2-{[(2s,3r,4s,5s,6r)-2-{[(2r,3r,4r,5r)-5-acetamido-1,2-dihydroxy-6-oxo-4-{[(2s,3s,4r,5s,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}hexan-3-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-4-hydroxy-6-[(1r,2r)-1,2,3-trihydrox Chemical compound O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@H]1O[C@H]([C@@H](NC(C)=O)C=O)[C@@H]([C@H](O)CO)O[C@H]1[C@H](O)[C@@H](O[C@]2(O[C@H]([C@H](NC(C)=O)[C@@H](O)C2)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H](O)[C@@H](CO)O1 LAQPKDLYOBZWBT-NYLDSJSYSA-N 0.000 claims 1
• 210000001612 chondrocyte Anatomy 0.000 claims 1
• 206010012601 diabetes mellitus Diseases 0.000 claims 1
• 201000010099 disease Diseases 0.000 claims 1
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 210000001705 ectoderm cell Anatomy 0.000 claims 1
• 210000004039 endoderm cell Anatomy 0.000 claims 1
• 210000000442 hair follicle cell Anatomy 0.000 claims 1
• 208000019622 heart disease Diseases 0.000 claims 1
• 238000007654 immersion Methods 0.000 claims 1
• 238000001727 in vivo Methods 0.000 claims 1
• 210000002490 intestinal epithelial cell Anatomy 0.000 claims 1
• 230000007774 longterm Effects 0.000 claims 1
• 230000014759 maintenance of location Effects 0.000 claims 1
• 210000001704 mesoblast Anatomy 0.000 claims 1
• 210000003061 neural cell Anatomy 0.000 claims 1
• 208000015122 neurodegenerative disease Diseases 0.000 claims 1
• 210000002569 neuron Anatomy 0.000 claims 1
• 230000006911 nucleation Effects 0.000 claims 1
• 238000010899 nucleation Methods 0.000 claims 1
• 210000000056 organ Anatomy 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 238000002360 preparation method Methods 0.000 claims 1
• 230000002265 prevention Effects 0.000 claims 1
• 210000002966 serum Anatomy 0.000 claims 1
• 238000002791 soaking Methods 0.000 claims 1
• 230000000638 stimulation Effects 0.000 claims 1
• 210000001519 tissue Anatomy 0.000 claims 1