JP2014509595A5 - - Google Patents

Download PDF

Info

Publication number
JP2014509595A5
JP2014509595A5 JP2013558234A JP2013558234A JP2014509595A5 JP 2014509595 A5 JP2014509595 A5 JP 2014509595A5 JP 2013558234 A JP2013558234 A JP 2013558234A JP 2013558234 A JP2013558234 A JP 2013558234A JP 2014509595 A5 JP2014509595 A5 JP 2014509595A5
Authority
JP
Japan
Prior art keywords
cancer
seq
immunotherapeutic composition
brachyury
yeast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013558234A
Other languages
English (en)
Japanese (ja)
Other versions
JP6068368B2 (ja
JP2014509595A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/029636 external-priority patent/WO2012125998A1/en
Publication of JP2014509595A publication Critical patent/JP2014509595A/ja
Publication of JP2014509595A5 publication Critical patent/JP2014509595A5/ja
Application granted granted Critical
Publication of JP6068368B2 publication Critical patent/JP6068368B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013558234A 2011-03-17 2012-03-19 酵母−ブラキュリ免疫治療組成物 Active JP6068368B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161453656P 2011-03-17 2011-03-17
US61/453,656 2011-03-17
PCT/US2012/029636 WO2012125998A1 (en) 2011-03-17 2012-03-19 Yeast-brachyury immunotherapeutic compositions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016249307A Division JP6309607B2 (ja) 2011-03-17 2016-12-22 酵母−ブラキュリ免疫治療組成物

Publications (3)

Publication Number Publication Date
JP2014509595A JP2014509595A (ja) 2014-04-21
JP2014509595A5 true JP2014509595A5 (enExample) 2015-04-30
JP6068368B2 JP6068368B2 (ja) 2017-01-25

Family

ID=46831122

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2013558234A Active JP6068368B2 (ja) 2011-03-17 2012-03-19 酵母−ブラキュリ免疫治療組成物
JP2016249307A Active JP6309607B2 (ja) 2011-03-17 2016-12-22 酵母−ブラキュリ免疫治療組成物
JP2018046148A Active JP6580733B2 (ja) 2011-03-17 2018-03-14 酵母−ブラキュリ免疫治療組成物
JP2019155138A Pending JP2019199484A (ja) 2011-03-17 2019-08-28 酵母−ブラキュリ免疫治療組成物

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2016249307A Active JP6309607B2 (ja) 2011-03-17 2016-12-22 酵母−ブラキュリ免疫治療組成物
JP2018046148A Active JP6580733B2 (ja) 2011-03-17 2018-03-14 酵母−ブラキュリ免疫治療組成物
JP2019155138A Pending JP2019199484A (ja) 2011-03-17 2019-08-28 酵母−ブラキュリ免疫治療組成物

Country Status (19)

Country Link
US (5) US9198941B2 (enExample)
EP (2) EP2685995B1 (enExample)
JP (4) JP6068368B2 (enExample)
KR (1) KR102046449B1 (enExample)
CN (1) CN103648513B (enExample)
AU (3) AU2012228937B2 (enExample)
BR (1) BR112013023456B1 (enExample)
CA (1) CA2835475C (enExample)
DK (1) DK2685995T3 (enExample)
ES (1) ES2627979T3 (enExample)
HK (1) HK1245649A1 (enExample)
HU (1) HUE033491T2 (enExample)
IL (1) IL228421B (enExample)
MX (1) MX350661B (enExample)
PL (1) PL2685995T3 (enExample)
PT (1) PT2685995T (enExample)
RU (2) RU2619850C2 (enExample)
SG (2) SG193396A1 (enExample)
WO (1) WO2012125998A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2170384T3 (en) 2007-07-02 2016-07-25 Etubics Corp METHODS AND COMPOSITIONS FOR THE PRODUCTION OF AN adenovirus vector for use in higher vaccination
EP2651439B1 (en) 2010-12-17 2018-09-19 Globeimmune, Inc. Compositions and methods for the treatment or prevention of human adenovirus-36 infection
AP2013007110A0 (en) 2011-02-12 2013-09-30 Globeimmune Inc Yeast-based therapeutic for chronic hepatitis B infection
AU2012228937B2 (en) 2011-03-17 2016-11-03 Globeimmune, Inc. Yeast-Brachyury immunotherapeutic compositions
BR112013032381B1 (pt) 2011-06-14 2021-01-12 Globeimmune, Inc. composições à base de levedura e métodos para o tratamento ou prevenção de infecção pelo vírus da hepatite delta
RU2017143985A (ru) 2011-08-17 2019-02-14 Глоубиммьюн, Инк. Иммунотерапевтические композиции на основе дрожжей-muc1 и способы их применения
EP2864792A1 (en) 2012-06-26 2015-04-29 Biodesix, Inc. Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies
US9605276B2 (en) 2012-08-24 2017-03-28 Etubics Corporation Replication defective adenovirus vector in vaccination
EP2895191B1 (en) * 2012-09-14 2019-06-05 The U.S.A. as represented by the Secretary, Department of Health and Human Services Brachyury protein, adenoviral vectors encoding brachyury protein, and their use
WO2014186047A1 (en) * 2013-03-19 2014-11-20 Globeimmune, Inc. Yeast-based immunotherapy for chordoma
WO2014160747A2 (en) 2013-03-26 2014-10-02 Globeimmune, Inc. Compositions and methods for the treatment or prevention of human immunodeficiency virus infection
US9725494B2 (en) * 2013-05-17 2017-08-08 United States Of America, As Represented By The Secretary, Department Of Health And Human Services Soluble CD27 (sCD27) and the use thereof
TWI654200B (zh) 2013-08-30 2019-03-21 環球免疫公司 治療或預防結核病的組合物及方法
KR102409372B1 (ko) 2014-04-11 2022-06-16 글로브이뮨 효모 면역 요법 및 타입 i 인터페론 감도
JP6647315B2 (ja) 2015-01-09 2020-02-14 イーチュービクス コーポレイション 組み合わせ免疫療法のための方法および組成物
EP3286213B1 (en) 2015-04-20 2021-08-04 Etubics Corporation Methods and compositions for combination immunotherapy
WO2017023840A1 (en) * 2015-08-03 2017-02-09 Globeimmune, Inc. Modified yeast-brachyury immunotherapeutic compositions
CN116196403A (zh) * 2015-08-03 2023-06-02 美国卫生和人力服务部 Brachyury缺失突变体、编码该缺失突变体的非酵母载体及其用途
WO2017222619A2 (en) 2016-03-24 2017-12-28 Nantcell, Inc. Sequence arrangements and sequences for neoepitope presentation
WO2017210562A1 (en) * 2016-06-03 2017-12-07 Etubics Corporation Compositions and methods for tumor vaccination using prostate cancer-associated antigens
EP3541400B1 (en) * 2016-11-18 2025-05-14 Sanford Burnham Prebys Medical Discovery Institute Gut microbiota and treatment of cancer
WO2018200389A1 (en) 2017-04-24 2018-11-01 Nantcell, Inc. Targeted neoepitope vectors and methods therefor
JP7062754B2 (ja) * 2017-08-15 2022-05-06 ナントセル,インコーポレイテッド haNKセツキシマブ併用及び方法
CN119818663A (zh) 2018-05-15 2025-04-15 全球免疫公司 用于诱导细胞免疫应答的重组酵母裂解物
US11857620B2 (en) 2020-03-11 2024-01-02 Immunitybio, Inc. Method of inducing immunity against SARS-CoV-2 using spike (s) and nucleocapsid (N)-ETSD immunogens delivered by a replication-defective adenovirus
US12285480B2 (en) 2020-03-11 2025-04-29 Nantcell, Inc. Method of inducing immunity against SARS-CoV-2 using spike and nucleocapsid-ETSD immunogens delivered by RNA and replication-defective adenoviruses
US20210284716A1 (en) 2020-03-11 2021-09-16 Immunitybio, Inc. ACE2-Fc Trap
TWI843989B (zh) 2021-02-19 2024-06-01 美商美威高能離子醫療系統公司 用於粒子治療系統之支架

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1036329A (en) 1908-11-19 1912-08-20 Edison Inc Thomas A Phonograph-reproducer.
FR2486400B1 (fr) 1980-07-09 1986-05-30 Univablot Medicaments a base de levures ou de leurs extraits insolubles
NZ199722A (en) 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
US4775622A (en) 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast
US5310654A (en) 1985-07-31 1994-05-10 The Board Of Trustees Of The Leland Stanford Junior University Method for determining virulence of Yersinia
US5234830A (en) 1988-02-03 1993-08-10 Suntory Limited DNA encoding a KEX2 endoprotease without a C-terminal hydrophobic region
IL95019A0 (en) 1989-08-09 1991-06-10 Mycogen Corp Process for encapsulation of biologicals
US5413914A (en) 1993-07-07 1995-05-09 The Regents Of The University Of Colorado Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases
US5830463A (en) 1993-07-07 1998-11-03 University Technology Corporation Yeast-based delivery vehicles
US5858378A (en) 1996-05-02 1999-01-12 Galagen, Inc. Pharmaceutical composition comprising cryptosporidium parvum oocysts antigen and whole cell candida species antigen
US20020044948A1 (en) 2000-03-15 2002-04-18 Samir Khleif Methods and compositions for co-stimulation of immunological responses to peptide antigens
ES2260078T3 (es) 2000-04-06 2006-11-01 Seer Pharmaceuticals, Llc. Sistema de administracion microbiana.
US7083787B2 (en) 2000-11-15 2006-08-01 Globeimmune, Inc. Yeast-dendritic cell vaccines and uses thereof
AU2003301021C1 (en) 2002-12-16 2010-02-18 Globelmmune, Inc. Yeast-based vaccines as immunotherapy
US7439042B2 (en) 2002-12-16 2008-10-21 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
US20100034840A1 (en) * 2005-07-11 2010-02-11 David Apelian Compositions and methods for eliciting an immune response to escape mutants of targeted therapies
US20070172503A1 (en) 2005-12-13 2007-07-26 Mycologics,Inc. Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines
MX2008009929A (es) * 2006-02-02 2008-10-01 Globeimmune Inc Vacuna a base de levadura para inducir una respuesta inmune.
CN101448848B (zh) * 2006-03-27 2013-12-04 全球免疫股份有限公司 Ras突变及其相关组合物和方法
JP5570819B2 (ja) 2007-02-02 2014-08-13 グローブイミューン,インコーポレイテッド 酵母を含む組成物および酵母を増殖させる方法
DK2918598T3 (en) * 2007-02-28 2019-04-29 The Govt Of U S A As Represented By The Secretary Of The Dept Of Health And Human Services Brachyury polypeptides and methods of use
EP2134358A1 (en) 2007-03-19 2009-12-23 Globeimmune, Inc. Compositions and methods for targeted ablation of mutational escape of targeted therapies for cancer
WO2009042642A2 (en) 2007-09-24 2009-04-02 President And Fellows Of Harvard College Compositions and methods for the treatment and prevention of ulcerative colitis and colon cancer
US8728489B2 (en) 2008-09-19 2014-05-20 Globeimmune, Inc. Immunotherapy for chronic hepatitis C virus infection
WO2010065626A1 (en) 2008-12-02 2010-06-10 Globeimmune, Inc. Genotyping tools, methods and kits
EP2419126B1 (en) * 2009-04-17 2018-01-10 Globeimmune, Inc. Combination immunotherapy compositions against cancer and methods
JP5913103B2 (ja) 2009-09-14 2016-04-27 ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイトTHE REGENTS OF THE UNIVERSITY OF COLORADO,a body corporate 酵母ベースの免疫療法組成物を含む組合せ物及び被験者のスクリーニング方法
JP2013522302A (ja) 2010-03-14 2013-06-13 グローブイミューン,インコーポレイテッド 酵母系免疫療法を使用した感染症の薬理ゲノミクス及び治療反応性ガイド治療
WO2012019127A2 (en) * 2010-08-05 2012-02-09 The Regents Of The University Of Colorado Combination yeast-based immunotherapy and arginine therapy for the treatment of myeloid-derived supressor cell-associated diseases
EP2651439B1 (en) 2010-12-17 2018-09-19 Globeimmune, Inc. Compositions and methods for the treatment or prevention of human adenovirus-36 infection
AP2013007110A0 (en) 2011-02-12 2013-09-30 Globeimmune Inc Yeast-based therapeutic for chronic hepatitis B infection
AU2012228937B2 (en) 2011-03-17 2016-11-03 Globeimmune, Inc. Yeast-Brachyury immunotherapeutic compositions
BR112013032381B1 (pt) 2011-06-14 2021-01-12 Globeimmune, Inc. composições à base de levedura e métodos para o tratamento ou prevenção de infecção pelo vírus da hepatite delta
RU2017143985A (ru) 2011-08-17 2019-02-14 Глоубиммьюн, Инк. Иммунотерапевтические композиции на основе дрожжей-muc1 и способы их применения

Similar Documents

Publication Publication Date Title
JP2014509595A5 (enExample)
RU2013146324A (ru) Иммунотерапевтические композиции на основе дрожжей с brachyury
Zhang et al. Personalized cancer vaccines: Targeting the cancer mutanome
JP2012524075A5 (enExample)
Kumai et al. Cancer immunotherapy: moving forward with peptide T cell vaccines
RU2014109741A (ru) Иммунотерапевтические композиции на основе дрожжей-muc1 и способы их применения
Perez et al. Active immunotherapy for non-small-cell lung cancer: moving toward a reality
IL294183A (en) shared neoantigens
JP2018501243A (ja) 組み換え型リステリア菌株を用いた併用療法
JP2019512020A5 (enExample)
JP2018522041A5 (enExample)
Baratta Glioblastoma is ‘hot’for personalized vaccines
Kameshima et al. Immunogenic enhancement and clinical effect by type‐I interferon of anti‐apoptotic protein, survivin‐derived peptide vaccine, in advanced colorectal cancer patients
EP4357356A3 (en) Antigenic peptides for prevention and treatment of b-cell malignancy
JP2020511139A5 (enExample)
RU2019132253A (ru) Новая днк-вакцина, нацеленная на pd-l1, для иммунотерапии рака
He et al. Low-dose paclitaxel enhances the anti-tumor efficacy of GM-CSF surface-modified whole-tumor-cell vaccine in mouse model of prostate cancer
Chen et al. The current therapeutic cancer vaccines landscape in non‐small cell lung cancer
Izzi et al. Poxvirus-based vaccines for cancer immunotherapy: New insights from combined cytokines/co-stimulatory molecules delivery and “uncommon” strains
Suzuki et al. Current status of vaccine immunotherapy for gastrointestinal cancers
JP2020507332A5 (enExample)
Han et al. P15. 07 safety and efficacy profile of TQB-2450 alone/with anlotinib in previously-treated advanced NSCLC: a phase IB single-arm trial
Morse et al. Current immunotherapeutic strategies in colon cancer
Mohapatra et al. Cancer Vaccines: Types, Mechanisms, and Recent Developments
Sasada et al. A patient with stage IV gastric cancer who acquired complete remission after undergoing multi-peptide dendritic cell immunotherapy in combination with standard therapies