JP2014505877A5 - - Google Patents
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- Publication number
- JP2014505877A5 JP2014505877A5 JP2013549812A JP2013549812A JP2014505877A5 JP 2014505877 A5 JP2014505877 A5 JP 2014505877A5 JP 2013549812 A JP2013549812 A JP 2013549812A JP 2013549812 A JP2013549812 A JP 2013549812A JP 2014505877 A5 JP2014505877 A5 JP 2014505877A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- bubr1
- level
- compound
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11151677.9 | 2011-01-21 | ||
| EP11151677 | 2011-01-21 | ||
| PCT/EP2012/050818 WO2012098207A1 (en) | 2011-01-21 | 2012-01-19 | Use of bubr1 as a biomarker of drug response to furazanobenzimidazoles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014505877A JP2014505877A (ja) | 2014-03-06 |
| JP2014505877A5 true JP2014505877A5 (https=) | 2015-03-12 |
| JP6302673B2 JP6302673B2 (ja) | 2018-03-28 |
Family
ID=43920866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013549812A Expired - Fee Related JP6302673B2 (ja) | 2011-01-21 | 2012-01-19 | フラザノベンゾイミダゾールに対する薬物応答のバイオマーカーとしてのｂｕｂｒ１の使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10222377B2 (https=) |
| EP (1) | EP2666016B1 (https=) |
| JP (1) | JP6302673B2 (https=) |
| CN (1) | CN103314295B (https=) |
| AU (1) | AU2012208520B2 (https=) |
| CA (2) | CA2822491C (https=) |
| DK (1) | DK2666016T3 (https=) |
| ES (1) | ES2620582T3 (https=) |
| HU (1) | HUE032643T2 (https=) |
| PL (1) | PL2666016T3 (https=) |
| PT (1) | PT2666016T (https=) |
| WO (1) | WO2012098207A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2691533B1 (en) * | 2011-03-29 | 2017-04-05 | Basilea Pharmaceutica AG | Use of phospho-akt as a biomarker of drug response |
| WO2015173341A1 (en) * | 2014-05-13 | 2015-11-19 | Basilea Pharmaceutica Ag | Dosage principle for anti-cancer furazanylbenzimidazoles |
| WO2017068182A1 (en) | 2015-10-22 | 2017-04-27 | Basilea Pharmaceutica Ag | Use of eb1 as a biomarker of drug response |
| MX2021011775A (es) | 2017-04-26 | 2023-01-10 | Basilea Pharm Int Ag | Procesos para la preparacion de furazanobencimidazoles y formas cristalinas de estos. |
| US11633383B2 (en) | 2017-05-16 | 2023-04-25 | Basilea Pharmaceutica International AG | Dosage principle for drugs useful for treating neoplastic diseases |
| CN107119137B (zh) * | 2017-05-26 | 2018-04-06 | 广州华弘生物科技有限公司 | 一种快速检测HER‑2/neu基因表达的检测试剂盒 |
| US11419856B2 (en) | 2017-11-20 | 2022-08-23 | Basilea Pharmaceutica International AG | Pharmaceutical combinations for use in the treatment of neoplastic diseases |
| WO2022053549A1 (en) | 2020-09-10 | 2022-03-17 | Basilea Pharmaceutica International AG | Use of c-myc as a biomarker of drug response |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6489137B2 (en) * | 1997-06-11 | 2002-12-03 | Chiron Corporation | Detection of loss of the wild-type huBUB1 gene |
| AU1614099A (en) | 1997-12-01 | 1999-06-16 | Fox Chase Cancer Center | Novel genes encoding proteins involved in mitotic checkpoint control and methodsof use thereof |
| CA2438092C (en) * | 2001-02-21 | 2011-08-09 | Chiron Corporation | Ttk in diagnosis and as a therapeutic target in cancer |
| MXPA05006920A (es) * | 2002-12-24 | 2006-02-10 | Astrazeneca Ab | Compuestos de quinazolina. |
| WO2004103994A1 (en) * | 2003-05-23 | 2004-12-02 | Basilea Pharmaceutica Ag | Furazanobenzimidazoles |
| US20050136177A1 (en) * | 2003-08-25 | 2005-06-23 | Anthony Hesse | Method for coloring landscaping materials using foamable dry colorant |
| US8021831B2 (en) * | 2003-08-25 | 2011-09-20 | Board Of Regents, The University Of Texas System | Taxane chemosensitivity prediction test |
| SG156625A1 (en) * | 2004-12-08 | 2009-11-26 | Aventis Pharma Inc | Method for measuring resistance or sensitivity to docetaxel |
| JP2009173629A (ja) * | 2007-12-21 | 2009-08-06 | Banyu Pharmaceut Co Ltd | Ｒｓｋ１阻害作用を有する新規スピロインダン誘導体 |
| MX2010013843A (es) * | 2008-06-26 | 2011-01-21 | Nerviano Medical Sciences Srl | Pirazolo-quinazolinas. |
| UA106763C2 (uk) * | 2009-07-27 | 2014-10-10 | Базілеа Фармас'Ютіка Аг | Фуразанобензимідазоли як проліки для лікування пухлинних або аутоімунних захворювань |
-
2012
- 2012-01-19 CA CA2822491A patent/CA2822491C/en active Active
- 2012-01-19 AU AU2012208520A patent/AU2012208520B2/en not_active Ceased
- 2012-01-19 PT PT127013415T patent/PT2666016T/pt unknown
- 2012-01-19 WO PCT/EP2012/050818 patent/WO2012098207A1/en not_active Ceased
- 2012-01-19 CA CA3142576A patent/CA3142576A1/en active Pending
- 2012-01-19 PL PL12701341T patent/PL2666016T3/pl unknown
- 2012-01-19 US US13/980,180 patent/US10222377B2/en active Active
- 2012-01-19 ES ES12701341.5T patent/ES2620582T3/es active Active
- 2012-01-19 JP JP2013549812A patent/JP6302673B2/ja not_active Expired - Fee Related
- 2012-01-19 CN CN201280005583.6A patent/CN103314295B/zh not_active Expired - Fee Related
- 2012-01-19 HU HUE12701341A patent/HUE032643T2/en unknown
- 2012-01-19 EP EP12701341.5A patent/EP2666016B1/en active Active
- 2012-01-19 DK DK12701341.5T patent/DK2666016T3/en active
-
2016
- 2016-03-04 US US15/060,998 patent/US9970938B2/en active Active
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