JP2014504651A5 - - Google Patents
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- Publication number
- JP2014504651A5 JP2014504651A5 JP2013552721A JP2013552721A JP2014504651A5 JP 2014504651 A5 JP2014504651 A5 JP 2014504651A5 JP 2013552721 A JP2013552721 A JP 2013552721A JP 2013552721 A JP2013552721 A JP 2013552721A JP 2014504651 A5 JP2014504651 A5 JP 2014504651A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- cypress
- suspension culture
- pcv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 238000004114 suspension culture Methods 0.000 claims description 29
- 239000002609 medium Substances 0.000 claims description 28
- 241000218691 Cupressaceae Species 0.000 claims description 26
- 239000007788 liquid Substances 0.000 claims description 24
- 206010020649 Hyperkeratosis Diseases 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 18
- CWEZAWNPTYBADX-UHFFFAOYSA-N Procyanidin Natural products OC1C(OC2C(O)C(Oc3c2c(O)cc(O)c3C4C(O)C(Oc5cc(O)cc(O)c45)c6ccc(O)c(O)c6)c7ccc(O)c(O)c7)c8c(O)cc(O)cc8OC1c9ccc(O)c(O)c9 CWEZAWNPTYBADX-UHFFFAOYSA-N 0.000 claims description 17
- 229920002414 procyanidin Polymers 0.000 claims description 17
- 244000078534 Vaccinium myrtillus Species 0.000 claims description 16
- 235000017537 Vaccinium myrtillus Nutrition 0.000 claims description 16
- 150000008442 polyphenolic compounds Chemical class 0.000 claims description 16
- 235000013824 polyphenols Nutrition 0.000 claims description 16
- 238000004113 cell culture Methods 0.000 claims description 13
- 235000021028 berry Nutrition 0.000 claims description 9
- 229930002877 anthocyanin Natural products 0.000 claims description 7
- 235000010208 anthocyanin Nutrition 0.000 claims description 7
- 239000004410 anthocyanin Substances 0.000 claims description 7
- 150000004636 anthocyanins Chemical class 0.000 claims description 7
- 239000000725 suspension Substances 0.000 claims description 7
- 235000000346 sugar Nutrition 0.000 claims description 6
- XFZJEEAOWLFHDH-UHFFFAOYSA-N (2R,2'R,3R,3'R,4R)-3,3',4',5,7-Pentahydroxyflavan(48)-3,3',4',5,7-pentahydroxyflavan Natural products C=12OC(C=3C=C(O)C(O)=CC=3)C(O)CC2=C(O)C=C(O)C=1C(C1=C(O)C=C(O)C=C1O1)C(O)C1C1=CC=C(O)C(O)=C1 XFZJEEAOWLFHDH-UHFFFAOYSA-N 0.000 claims description 5
- MOJZMWJRUKIQGL-FWCKPOPSSA-N Procyanidin C2 Natural products O[C@@H]1[C@@H](c2cc(O)c(O)cc2)Oc2c([C@H]3[C@H](O)[C@@H](c4cc(O)c(O)cc4)Oc4c3c(O)cc(O)c4)c(O)cc(O)c2[C@@H]1c1c(O)cc(O)c2c1O[C@@H]([C@H](O)C2)c1cc(O)c(O)cc1 MOJZMWJRUKIQGL-FWCKPOPSSA-N 0.000 claims description 5
- HGVVOUNEGQIPMS-UHFFFAOYSA-N procyanidin Chemical compound O1C2=CC(O)=CC(O)=C2C(O)C(O)C1(C=1C=C(O)C(O)=CC=1)OC1CC2=C(O)C=C(O)C=C2OC1C1=CC=C(O)C(O)=C1 HGVVOUNEGQIPMS-UHFFFAOYSA-N 0.000 claims description 5
- 239000012737 fresh medium Substances 0.000 claims description 4
- 238000012258 culturing Methods 0.000 claims description 2
- 238000003756 stirring Methods 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims 7
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 5
- 229930006000 Sucrose Natural products 0.000 claims 5
- 239000005720 sucrose Substances 0.000 claims 5
- 238000009825 accumulation Methods 0.000 claims 2
- 230000035755 proliferation Effects 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 description 7
- 241000196324 Embryophyta Species 0.000 description 5
- 244000299461 Theobroma cacao Species 0.000 description 3
- 235000005764 Theobroma cacao ssp. cacao Nutrition 0.000 description 3
- 235000005767 Theobroma cacao ssp. sphaerocarpum Nutrition 0.000 description 3
- 240000000038 Ziziphus mauritiana Species 0.000 description 3
- 235000006545 Ziziphus mauritiana Nutrition 0.000 description 3
- 235000001046 cacaotero Nutrition 0.000 description 3
- 238000004587 chromatography analysis Methods 0.000 description 3
- 235000012511 Vaccinium Nutrition 0.000 description 2
- 241000736767 Vaccinium Species 0.000 description 2
- 230000006698 induction Effects 0.000 description 2
- 229920002323 Silicone foam Polymers 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000000539 dimer Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000013638 trimer Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161439675P | 2011-02-04 | 2011-02-04 | |
| US61/439,675 | 2011-02-04 | ||
| PCT/US2012/024008 WO2012106723A1 (en) | 2011-02-04 | 2012-02-06 | Polyphenol production by vaccinium myrtillus cell cultures |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014504651A JP2014504651A (ja) | 2014-02-24 |
| JP2014504651A5 true JP2014504651A5 (enExample) | 2015-03-26 |
Family
ID=46603117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013552721A Pending JP2014504651A (ja) | 2011-02-04 | 2012-02-06 | セイヨウスノキ細胞培養によるポリフェノール産生 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20130323843A1 (enExample) |
| EP (1) | EP2670247A4 (enExample) |
| JP (1) | JP2014504651A (enExample) |
| CN (1) | CN103459589A (enExample) |
| AU (1) | AU2012211969B2 (enExample) |
| WO (1) | WO2012106723A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6211380B2 (ja) * | 2012-10-17 | 2017-10-11 | 丸善製薬株式会社 | Ｔｉｅ２活性化剤、血管新生抑制剤、血管の成熟化剤、血管の正常化剤、及び血管の安定化剤 |
| EP3013428A1 (en) * | 2013-06-26 | 2016-05-04 | Dianaplantsciences, Inc. | Incorporation of cultured bilberry cells in cosmetics, dietary supplements, and/or functional foods |
| CN104435078B (zh) * | 2014-12-16 | 2018-11-16 | 汤臣倍健股份有限公司 | 一种组合物及其应用和制剂 |
| US20180264060A1 (en) | 2017-03-15 | 2018-09-20 | Tokiwa Phytochemical Co., Ltd. | Composition for preventing, or precaution for dry eye |
| EP4461129A1 (en) | 2023-05-09 | 2024-11-13 | ZHAW - Zürcher Hochschule für Angewandte Wissenschaften | Edible plant cell culture biomass based on fruit endocarp and/or seed explants and methods of its preparation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010114567A1 (en) * | 2009-04-03 | 2010-10-07 | Dianaplantsciences, Inc. | Production and extraction of procyanidins from plant cell cultures |
-
2012
- 2012-02-06 CN CN2012800152145A patent/CN103459589A/zh active Pending
- 2012-02-06 EP EP12742249.1A patent/EP2670247A4/en not_active Withdrawn
- 2012-02-06 US US13/983,537 patent/US20130323843A1/en not_active Abandoned
- 2012-02-06 JP JP2013552721A patent/JP2014504651A/ja active Pending
- 2012-02-06 WO PCT/US2012/024008 patent/WO2012106723A1/en not_active Ceased
- 2012-02-06 AU AU2012211969A patent/AU2012211969B2/en not_active Expired - Fee Related
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