JP2014501759A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014501759A5 JP2014501759A5 JP2013546226A JP2013546226A JP2014501759A5 JP 2014501759 A5 JP2014501759 A5 JP 2014501759A5 JP 2013546226 A JP2013546226 A JP 2013546226A JP 2013546226 A JP2013546226 A JP 2013546226A JP 2014501759 A5 JP2014501759 A5 JP 2014501759A5
- Authority
- JP
- Japan
- Prior art keywords
- animal
- carotene
- vitamin
- group
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 38
- 241001465754 Metazoa Species 0.000 claims 22
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 20
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 20
- ANVAOWXLWRTKGA-XHGAXZNDSA-N all-trans-alpha-carotene Chemical compound CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1C(C)=CCCC1(C)C ANVAOWXLWRTKGA-XHGAXZNDSA-N 0.000 claims 20
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 claims 20
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 claims 18
- 206010022489 Insulin Resistance Diseases 0.000 claims 17
- 239000003963 antioxidant agent Substances 0.000 claims 15
- 230000003078 antioxidant effect Effects 0.000 claims 15
- 235000006708 antioxidants Nutrition 0.000 claims 15
- JBYXPOFIGCOSSB-GOJKSUSPSA-N 9-cis,11-trans-octadecadienoic acid Chemical compound CCCCCC\C=C\C=C/CCCCCCCC(O)=O JBYXPOFIGCOSSB-GOJKSUSPSA-N 0.000 claims 12
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 12
- 229940108924 conjugated linoleic acid Drugs 0.000 claims 12
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 12
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 claims 12
- 210000000577 adipose tissue Anatomy 0.000 claims 11
- 239000003638 chemical reducing agent Substances 0.000 claims 11
- 239000003795 chemical substances by application Substances 0.000 claims 11
- 239000003623 enhancer Substances 0.000 claims 11
- JKQXZKUSFCKOGQ-JLGXGRJMSA-N (3R,3'R)-beta,beta-carotene-3,3'-diol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-JLGXGRJMSA-N 0.000 claims 10
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 10
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 claims 10
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 claims 10
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims 10
- 229930003268 Vitamin C Natural products 0.000 claims 10
- 229930003427 Vitamin E Natural products 0.000 claims 10
- JKQXZKUSFCKOGQ-LQFQNGICSA-N Z-zeaxanthin Natural products C([C@H](O)CC=1C)C(C)(C)C=1C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-LQFQNGICSA-N 0.000 claims 10
- QOPRSMDTRDMBNK-RNUUUQFGSA-N Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCC(O)C1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C QOPRSMDTRDMBNK-RNUUUQFGSA-N 0.000 claims 10
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 claims 10
- JKQXZKUSFCKOGQ-LOFNIBRQSA-N all-trans-Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C JKQXZKUSFCKOGQ-LOFNIBRQSA-N 0.000 claims 10
- 239000011795 alpha-carotene Substances 0.000 claims 10
- 235000003903 alpha-carotene Nutrition 0.000 claims 10
- ANVAOWXLWRTKGA-HLLMEWEMSA-N alpha-carotene Natural products C(=C\C=C\C=C(/C=C/C=C(\C=C\C=1C(C)(C)CCCC=1C)/C)\C)(\C=C\C=C(/C=C/[C@H]1C(C)=CCCC1(C)C)\C)/C ANVAOWXLWRTKGA-HLLMEWEMSA-N 0.000 claims 10
- 235000013734 beta-carotene Nutrition 0.000 claims 10
- 239000011648 beta-carotene Substances 0.000 claims 10
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 claims 10
- 229960002747 betacarotene Drugs 0.000 claims 10
- 235000012680 lutein Nutrition 0.000 claims 10
- 239000001656 lutein Substances 0.000 claims 10
- 229960005375 lutein Drugs 0.000 claims 10
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 claims 10
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 claims 10
- 235000012661 lycopene Nutrition 0.000 claims 10
- 239000001751 lycopene Substances 0.000 claims 10
- 229960004999 lycopene Drugs 0.000 claims 10
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 claims 10
- 235000011649 selenium Nutrition 0.000 claims 10
- 239000011669 selenium Substances 0.000 claims 10
- 229910052711 selenium Inorganic materials 0.000 claims 10
- 229940091258 selenium supplement Drugs 0.000 claims 10
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 claims 10
- 235000019154 vitamin C Nutrition 0.000 claims 10
- 239000011718 vitamin C Substances 0.000 claims 10
- 235000019165 vitamin E Nutrition 0.000 claims 10
- 239000011709 vitamin E Substances 0.000 claims 10
- 229940046009 vitamin E Drugs 0.000 claims 10
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 claims 10
- 235000010930 zeaxanthin Nutrition 0.000 claims 10
- 239000001775 zeaxanthin Substances 0.000 claims 10
- 229940043269 zeaxanthin Drugs 0.000 claims 10
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 claims 10
- DMASLKHVQRHNES-UPOGUZCLSA-N (3R)-beta,beta-caroten-3-ol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C DMASLKHVQRHNES-UPOGUZCLSA-N 0.000 claims 8
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 claims 8
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims 8
- 108010087806 Carnosine Proteins 0.000 claims 8
- 239000004212 Cryptoxanthin Substances 0.000 claims 8
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims 8
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 claims 8
- 229960001009 acetylcarnitine Drugs 0.000 claims 8
- 239000002260 anti-inflammatory agent Substances 0.000 claims 8
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 8
- 235000002360 beta-cryptoxanthin Nutrition 0.000 claims 8
- DMASLKHVQRHNES-ITUXNECMSA-N beta-cryptoxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CCCC2(C)C DMASLKHVQRHNES-ITUXNECMSA-N 0.000 claims 8
- 229960004203 carnitine Drugs 0.000 claims 8
- 229940044199 carnosine Drugs 0.000 claims 8
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims 8
- 235000019244 cryptoxanthin Nutrition 0.000 claims 8
- 235000012754 curcumin Nutrition 0.000 claims 8
- 239000004148 curcumin Substances 0.000 claims 8
- 229940109262 curcumin Drugs 0.000 claims 8
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 claims 8
- 229940087603 grape seed extract Drugs 0.000 claims 8
- 235000002532 grape seed extract Nutrition 0.000 claims 8
- 239000001717 vitis vinifera seed extract Substances 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 7
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical group [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims 6
- 235000012721 chromium Nutrition 0.000 claims 6
- 239000011651 chromium Substances 0.000 claims 6
- 229940107218 chromium Drugs 0.000 claims 6
- 229910052804 chromium Inorganic materials 0.000 claims 6
- 235000005911 diet Nutrition 0.000 claims 6
- 230000037213 diet Effects 0.000 claims 6
- 235000021323 fish oil Nutrition 0.000 claims 6
- 238000009472 formulation Methods 0.000 claims 6
- 239000011701 zinc Substances 0.000 claims 6
- 229910052725 zinc Inorganic materials 0.000 claims 6
- 235000016804 zinc Nutrition 0.000 claims 6
- 235000014105 formulated food Nutrition 0.000 claims 5
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 claims 4
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims 4
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 claims 4
- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 claims 4
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 claims 4
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 4
- AGBQKNBQESQNJD-UHFFFAOYSA-N alpha-Lipoic acid Natural products OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 claims 4
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims 4
- 229940046374 chromium picolinate Drugs 0.000 claims 4
- GJYSUGXFENSLOO-UHFFFAOYSA-N chromium;pyridine-2-carboxylic acid Chemical compound [Cr].OC(=O)C1=CC=CC=N1.OC(=O)C1=CC=CC=N1.OC(=O)C1=CC=CC=N1 GJYSUGXFENSLOO-UHFFFAOYSA-N 0.000 claims 4
- 235000017803 cinnamon Nutrition 0.000 claims 4
- HJTVQHVGMGKONQ-LUZURFALSA-N demethoxycurcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=CC(O)=CC=2)=C1 HJTVQHVGMGKONQ-LUZURFALSA-N 0.000 claims 4
- XMOCLSLCDHWDHP-IUODEOHRSA-N epi-Gallocatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-IUODEOHRSA-N 0.000 claims 4
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims 4
- 235000019136 lipoic acid Nutrition 0.000 claims 4
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 4
- 229940012843 omega-3 fatty acid Drugs 0.000 claims 4
- 150000008442 polyphenolic compounds Chemical class 0.000 claims 4
- 235000013824 polyphenols Nutrition 0.000 claims 4
- NHZMQXZHNVQTQA-UHFFFAOYSA-N pyridoxamine Chemical compound CC1=NC=C(CO)C(CN)=C1O NHZMQXZHNVQTQA-UHFFFAOYSA-N 0.000 claims 4
- 235000021283 resveratrol Nutrition 0.000 claims 4
- 229940016667 resveratrol Drugs 0.000 claims 4
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims 4
- 229960002663 thioctic acid Drugs 0.000 claims 4
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 claims 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 3
- 239000008280 blood Substances 0.000 claims 3
- 210000004369 blood Anatomy 0.000 claims 3
- 239000008103 glucose Substances 0.000 claims 3
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 3
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims 2
- PFTAWBLQPZVEMU-ZFWWWQNUSA-N (+)-epicatechin Natural products C1([C@@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-ZFWWWQNUSA-N 0.000 claims 2
- WMBWREPUVVBILR-WIYYLYMNSA-N (-)-Epigallocatechin-3-o-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-WIYYLYMNSA-N 0.000 claims 2
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 claims 2
- LSHVYAFMTMFKBA-TZIWHRDSSA-N (-)-epicatechin-3-O-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=CC=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-TZIWHRDSSA-N 0.000 claims 2
- HMJSBVCDPKODEX-NXZHAISVSA-N (1e,6e)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione Chemical compound C1=C(OC)C(OC)=CC=C1\C=C\C(=O)CC(=O)\C=C\C1=CC=C(OC)C(OC)=C1 HMJSBVCDPKODEX-NXZHAISVSA-N 0.000 claims 2
- MJYQFWSXKFLTAY-OVEQLNGDSA-N (2r,3r)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butane-1,4-diol;(2r,3r,4s,5s,6r)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O.C1=C(O)C(OC)=CC(C[C@@H](CO)[C@H](CO)CC=2C=C(OC)C(O)=CC=2)=C1 MJYQFWSXKFLTAY-OVEQLNGDSA-N 0.000 claims 2
- JPFCOVZKLAXXOE-XBNSMERZSA-N (3r)-2-(3,5-dihydroxy-4-methoxyphenyl)-8-[(2r,3r,4r)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2h-chromen-4-yl]-3,4-dihydro-2h-chromene-3,5,7-triol Chemical compound C1=C(O)C(OC)=C(O)C=C1C1[C@H](O)CC(C(O)=CC(O)=C2[C@H]3C4=C(O)C=C(O)C=C4O[C@@H]([C@@H]3O)C=3C=CC(O)=CC=3)=C2O1 JPFCOVZKLAXXOE-XBNSMERZSA-N 0.000 claims 2
- YUFFSWGQGVEMMI-JLNKQSITSA-N (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O YUFFSWGQGVEMMI-JLNKQSITSA-N 0.000 claims 2
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 claims 2
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 claims 2
- 125000004203 4-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims 2
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 claims 2
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 claims 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 2
- 240000007154 Coffea arabica Species 0.000 claims 2
- 235000021294 Docosapentaenoic acid Nutrition 0.000 claims 2
- LSHVYAFMTMFKBA-UHFFFAOYSA-N ECG Natural products C=1C=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-UHFFFAOYSA-N 0.000 claims 2
- WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 claims 2
- 108010024636 Glutathione Proteins 0.000 claims 2
- 241000208680 Hamamelis mollis Species 0.000 claims 2
- 240000007049 Juglans regia Species 0.000 claims 2
- 235000009496 Juglans regia Nutrition 0.000 claims 2
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 2
- XMOCLSLCDHWDHP-UHFFFAOYSA-N L-Epigallocatechin Natural products OC1CC2=C(O)C=C(O)C=C2OC1C1=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-UHFFFAOYSA-N 0.000 claims 2
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 claims 2
- 229920001991 Proanthocyanidin Polymers 0.000 claims 2
- 241000209140 Triticum Species 0.000 claims 2
- 235000021307 Triticum Nutrition 0.000 claims 2
- 229960001138 acetylsalicylic acid Drugs 0.000 claims 2
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 2
- 229930002945 all-trans-retinaldehyde Natural products 0.000 claims 2
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims 2
- HAMNKKUPIHEESI-UHFFFAOYSA-N aminoguanidine Chemical compound NNC(N)=N HAMNKKUPIHEESI-UHFFFAOYSA-N 0.000 claims 2
- 235000010208 anthocyanin Nutrition 0.000 claims 2
- 239000004410 anthocyanin Substances 0.000 claims 2
- 229930002877 anthocyanin Natural products 0.000 claims 2
- 150000004636 anthocyanins Chemical class 0.000 claims 2
- 235000013793 astaxanthin Nutrition 0.000 claims 2
- 239000001168 astaxanthin Substances 0.000 claims 2
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 claims 2
- 229940022405 astaxanthin Drugs 0.000 claims 2
- 229960002873 benfotiamine Drugs 0.000 claims 2
- BTNNPSLJPBRMLZ-LGMDPLHJSA-N benfotiamine Chemical compound C=1C=CC=CC=1C(=O)SC(/CCOP(O)(O)=O)=C(/C)N(C=O)CC1=CN=C(C)N=C1N BTNNPSLJPBRMLZ-LGMDPLHJSA-N 0.000 claims 2
- JYTVKRNTTALBBZ-UHFFFAOYSA-N bis demethoxycurcumin Natural products C1=CC(O)=CC=C1C=CC(=O)CC(=O)C=CC1=CC=CC(O)=C1 JYTVKRNTTALBBZ-UHFFFAOYSA-N 0.000 claims 2
- PREBVFJICNPEKM-YDWXAUTNSA-N bisdemethoxycurcumin Chemical compound C1=CC(O)=CC=C1\C=C\C(=O)CC(=O)\C=C\C1=CC=C(O)C=C1 PREBVFJICNPEKM-YDWXAUTNSA-N 0.000 claims 2
- 229940074360 caffeic acid Drugs 0.000 claims 2
- 235000004883 caffeic acid Nutrition 0.000 claims 2
- 235000019519 canola oil Nutrition 0.000 claims 2
- 239000000828 canola oil Substances 0.000 claims 2
- 235000021466 carotenoid Nutrition 0.000 claims 2
- 150000001747 carotenoids Chemical class 0.000 claims 2
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 claims 2
- 235000005487 catechin Nutrition 0.000 claims 2
- 229940074393 chlorogenic acid Drugs 0.000 claims 2
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 claims 2
- 235000001368 chlorogenic acid Nutrition 0.000 claims 2
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 claims 2
- 229950001002 cianidanol Drugs 0.000 claims 2
- 235000020230 cinnamon extract Nutrition 0.000 claims 2
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 claims 2
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 claims 2
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 2
- 235000018417 cysteine Nutrition 0.000 claims 2
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims 2
- YXAKCQIIROBKOP-UHFFFAOYSA-N di-p-hydroxycinnamoylmethane Natural products C=1C=C(O)C=CC=1C=CC(=O)C=C(O)C=CC1=CC=C(O)C=C1 YXAKCQIIROBKOP-UHFFFAOYSA-N 0.000 claims 2
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 2
- 229940090949 docosahexaenoic acid Drugs 0.000 claims 2
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 2
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 2
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 2
- 235000012734 epicatechin Nutrition 0.000 claims 2
- LPTRNLNOHUVQMS-UHFFFAOYSA-N epicatechin Natural products Cc1cc(O)cc2OC(C(O)Cc12)c1ccc(O)c(O)c1 LPTRNLNOHUVQMS-UHFFFAOYSA-N 0.000 claims 2
- DZYNKLUGCOSVKS-UHFFFAOYSA-N epigallocatechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3cc(O)c(O)c(O)c3 DZYNKLUGCOSVKS-UHFFFAOYSA-N 0.000 claims 2
- 229940030275 epigallocatechin gallate Drugs 0.000 claims 2
- 239000000284 extract Substances 0.000 claims 2
- 235000004426 flaxseed Nutrition 0.000 claims 2
- 235000010382 gamma-tocopherol Nutrition 0.000 claims 2
- 235000003969 glutathione Nutrition 0.000 claims 2
- 229960003180 glutathione Drugs 0.000 claims 2
- 229960004488 linolenic acid Drugs 0.000 claims 2
- 235000021388 linseed oil Nutrition 0.000 claims 2
- 239000000944 linseed oil Substances 0.000 claims 2
- 150000004667 medium chain fatty acids Chemical group 0.000 claims 2
- 239000006014 omega-3 oil Substances 0.000 claims 2
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims 2
- 235000008151 pyridoxamine Nutrition 0.000 claims 2
- 239000011699 pyridoxamine Substances 0.000 claims 2
- 229940107700 pyruvic acid Drugs 0.000 claims 2
- 235000020945 retinal Nutrition 0.000 claims 2
- 239000011604 retinal Substances 0.000 claims 2
- 230000002207 retinal effect Effects 0.000 claims 2
- NCYCYZXNIZJOKI-OVSJKPMPSA-N retinal group Chemical group C\C(=C/C=O)\C=C\C=C(\C=C\C1=C(CCCC1(C)C)C)/C NCYCYZXNIZJOKI-OVSJKPMPSA-N 0.000 claims 2
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 claims 2
- 235000003687 soy isoflavones Nutrition 0.000 claims 2
- 229960003080 taurine Drugs 0.000 claims 2
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 2
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 claims 2
- 235000020234 walnut Nutrition 0.000 claims 2
- 229940118846 witch hazel Drugs 0.000 claims 2
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims 2
- 229960001763 zinc sulfate Drugs 0.000 claims 2
- 229910000368 zinc sulfate Inorganic materials 0.000 claims 2
- MQHUBPZUHMDZNT-UHFFFAOYSA-L zinc;methanedisulfonate Chemical compound [Zn+2].[O-]S(=O)(=O)CS([O-])(=O)=O MQHUBPZUHMDZNT-UHFFFAOYSA-L 0.000 claims 2
- QUEDXNHFTDJVIY-DQCZWYHMSA-N γ-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-DQCZWYHMSA-N 0.000 claims 2
- 239000002478 γ-tocopherol Substances 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061459901P | 2010-12-21 | 2010-12-21 | |
| US61/459,901 | 2010-12-21 | ||
| PCT/US2011/065156 WO2012087742A2 (en) | 2010-12-21 | 2011-12-15 | Methods and compositions suitable for managing blood glucose in animals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014501759A JP2014501759A (ja) | 2014-01-23 |
| JP2014501759A5 true JP2014501759A5 (enExample) | 2015-02-05 |
Family
ID=46314768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013546226A Pending JP2014501759A (ja) | 2010-12-21 | 2011-12-15 | 動物の血糖管理に適した方法及び組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20130316029A1 (enExample) |
| EP (1) | EP2654777A4 (enExample) |
| JP (1) | JP2014501759A (enExample) |
| CN (1) | CN103384529B (enExample) |
| AU (1) | AU2011349715A1 (enExample) |
| BR (1) | BR112013016021A2 (enExample) |
| CA (1) | CA2821807A1 (enExample) |
| MX (1) | MX2013007189A (enExample) |
| RU (1) | RU2013133994A (enExample) |
| WO (1) | WO2012087742A2 (enExample) |
| ZA (1) | ZA201305498B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9171343B1 (en) | 2012-09-11 | 2015-10-27 | Aseko, Inc. | Means and method for improved glycemic control for diabetic patients |
| US9897565B1 (en) | 2012-09-11 | 2018-02-20 | Aseko, Inc. | System and method for optimizing insulin dosages for diabetic subjects |
| CN102976962B (zh) * | 2012-11-20 | 2015-02-04 | 南京工业大学 | L-鸟氨酸阿司匹林复盐及其制备方法和应用 |
| JP6482874B2 (ja) * | 2012-12-13 | 2019-03-13 | ユニ・チャーム株式会社 | ペットフード |
| US20160051814A1 (en) * | 2013-04-15 | 2016-02-25 | Nestec S.A. | Use of whey protein in combination with electrical muscle stimulation |
| FR3017029B1 (fr) * | 2014-01-31 | 2016-02-19 | Nutra Canada | Principe actif nutritionnel obtenu a partir de vaccinium angustifolium, composition le contenant et utilisation |
| US9486580B2 (en) | 2014-01-31 | 2016-11-08 | Aseko, Inc. | Insulin management |
| US9233204B2 (en) | 2014-01-31 | 2016-01-12 | Aseko, Inc. | Insulin management |
| WO2016060426A1 (ko) * | 2014-10-13 | 2016-04-21 | 한국 한의학 연구원 | 백편두 추출물을 유효성분으로 포함하는 비알콜성 지방간질환의 예방 또는 개선용 조성물 |
| US11081226B2 (en) | 2014-10-27 | 2021-08-03 | Aseko, Inc. | Method and controller for administering recommended insulin dosages to a patient |
| AU2015339576B2 (en) | 2014-10-27 | 2020-02-06 | Glytec, Llc | Subcutaneous outpatient management |
| CN104304684B (zh) * | 2014-11-14 | 2016-11-16 | 广东海因特生物技术集团有限公司 | 一种提高鲫鱼抗应激能力的复合饲料添加剂 |
| CN104798997B (zh) * | 2015-04-09 | 2018-03-06 | 湖南农业大学 | 一种调节血糖的犬专用保健日粮及饲喂方法 |
| EP3337402A4 (en) | 2015-08-20 | 2019-04-24 | Aseko, Inc. | THERAPY ADVISOR FOR DIABETES MANAGEMENT |
| US10842169B2 (en) * | 2015-09-30 | 2020-11-24 | Hill's Pet Nutrition, Inc. | Pet food composition for managing non-food allergies |
| CN105285504B (zh) * | 2015-11-20 | 2019-02-26 | 南京农业大学 | 一种改善鱼体糖耐受性的调控组合物及其制备方法与应用 |
| CN105998058A (zh) * | 2016-06-29 | 2016-10-12 | 中国人民解放军第三军医大学第附属医院 | 用于预防和改善胰岛素抵抗的营养组合物及其应用 |
| CN107865873A (zh) * | 2016-09-23 | 2018-04-03 | 中国科学院生物物理研究所 | 苯磷硫胺在制备药物中的应用 |
| CA3072289A1 (en) * | 2017-08-06 | 2019-02-14 | Second Genome, Inc. | Streptococcus australis as a biotherapeutics |
| TWI751379B (zh) * | 2017-09-21 | 2022-01-01 | 奧孟亞股份有限公司 | 用於遞送胜肽之藥物組合物 |
| WO2019067087A1 (en) * | 2017-09-26 | 2019-04-04 | Second Genome, Inc. | GEMELLA SANGUINIS AS BIOTHERAPEUTIC AGENTS |
| US20210361698A1 (en) * | 2017-12-27 | 2021-11-25 | Suntory Holdings Limited | Composition for improving intestinal barrier function |
| EP4023225A4 (en) * | 2019-08-30 | 2023-08-30 | Institute Of Zoology, Chinese Academy Of Sciences | COMPOSITION USED FOR FIGHTING METABOLIC DISEASES AND USES OF THE COMPOSITION |
| CN112940967B (zh) * | 2021-02-06 | 2022-06-21 | 中南大学 | 一株发酵乳杆菌mf423及其发酵米糠提取物和它们的应用 |
| CN115843941A (zh) * | 2022-11-01 | 2023-03-28 | 西北农林科技大学 | 一种提升肉食性鱼类对糖利用及蛋白沉积率的高糖饲料 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5614224A (en) * | 1995-04-20 | 1997-03-25 | Womack; Rick W. | Nutritional supplement for diabetics |
| IT1275434B (it) * | 1995-05-19 | 1997-08-07 | Farmila Farma Milano | Composizioni farmaceutiche e/o dietetiche ad attivita' antiossidante |
| KR100354151B1 (ko) * | 1999-12-23 | 2002-09-28 | 대한민국(관리부서:농촌진흥청) | 기능성 항당뇨음료 |
| DE60104450T2 (de) * | 2000-09-21 | 2005-09-15 | Nutrition 21, Inc. | Chrom enthaltende zusammensetzung zur behandlung von diabetes, zur verbesserung der insulinsensitivität und zur reduktion von hyperglykämie, hypercholesterolämie und des körperfettanteils |
| US20030148016A1 (en) * | 2002-02-07 | 2003-08-07 | Choudhry Muhammad S. | Energy fitness water |
| BRPI0508936A (pt) * | 2004-03-17 | 2007-09-25 | Nestec Sa | composições e métodos para redução ou prevenção de obesidade |
| CN1320925C (zh) * | 2005-03-30 | 2007-06-13 | 淮北市辉克药业有限公司 | 长期使用的治疗糖尿病的复方制剂 |
| US20070231371A1 (en) * | 2006-02-01 | 2007-10-04 | Nestec, S. A. | Nutritional system and methods for increasing longevity |
| US7678785B2 (en) * | 2006-07-24 | 2010-03-16 | Ucb Pharma S.A. | Substituted aniline derivatives |
| JP5798281B2 (ja) * | 2006-09-27 | 2015-10-21 | 株式会社セラバリューズ | PPARγ活性化剤 |
| US20100247686A1 (en) * | 2007-04-04 | 2010-09-30 | Litao Zhong | Compositions and methods for obesity, diabetes and metabolic syndrome control and management |
| ES2664826T3 (es) * | 2007-10-25 | 2018-04-23 | Nutri Co., Ltd. | Composición para reducir el nivel glucosa, LDL modificada con malondialdehído, homocisteína y/o proteína c-reactiva en sangre |
| US8575217B2 (en) * | 2009-03-16 | 2013-11-05 | Genmedica Therapeutics Sl | Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders |
| MX340938B (es) * | 2010-01-06 | 2016-08-01 | Nestec Sa | Regimenes dieteticos utiles para imitar la restriccion calorica. |
| CA2816054A1 (en) * | 2010-10-27 | 2012-05-03 | Nestec S.A. | Methods and compositions suitable for promoting healthy skin |
-
2011
- 2011-12-15 CA CA2821807A patent/CA2821807A1/en not_active Abandoned
- 2011-12-15 AU AU2011349715A patent/AU2011349715A1/en not_active Abandoned
- 2011-12-15 RU RU2013133994/15A patent/RU2013133994A/ru unknown
- 2011-12-15 BR BR112013016021-7A patent/BR112013016021A2/en not_active IP Right Cessation
- 2011-12-15 MX MX2013007189A patent/MX2013007189A/es not_active Application Discontinuation
- 2011-12-15 JP JP2013546226A patent/JP2014501759A/ja active Pending
- 2011-12-15 US US13/996,245 patent/US20130316029A1/en not_active Abandoned
- 2011-12-15 CN CN201180067981.6A patent/CN103384529B/zh not_active Expired - Fee Related
- 2011-12-15 EP EP11851132.8A patent/EP2654777A4/en not_active Ceased
- 2011-12-15 WO PCT/US2011/065156 patent/WO2012087742A2/en not_active Ceased
-
2013
- 2013-07-19 ZA ZA2013/05498A patent/ZA201305498B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014501759A5 (enExample) | ||
| JP2013542222A5 (enExample) | ||
| RU2013133994A (ru) | Способы и композиции, применимые для контроля глюкозы в крови животных | |
| RU2008135334A (ru) | Пищевые системы и способы увеличения долголетия | |
| ES2312397T3 (es) | Metodo y preparacion para prevenir y/o tratar enfermedades vasculares y enfermedades secundarias asociadas a las mismas. | |
| RU2013124032A (ru) | Способы и композиции, подходящие для укрепления здоровья кожи | |
| JP5371429B2 (ja) | 機能的な血管の完全性及び細胞生存を改善し、脳の虚血における又は虚血エピソード後のアポトーシスを減少するための組成物及び方法 | |
| US20130108706A1 (en) | Dietary formulations | |
| US9849096B2 (en) | Neuroprotective effect of carotenoids in brain | |
| US20130337080A1 (en) | Dietary Supplements For Promotion of Growth, Repair and Maintenance of Bone and Joints | |
| JP2005535617A5 (enExample) | ||
| Braga et al. | Oral preoperative antioxidants in pancreatic surgery: a double-blind, randomized, clinical trial | |
| RU2006130739A (ru) | Питательная композиция для улучшения состояния кожи и предотвращения кожных заболеваний | |
| Saurat et al. | Retinoids | |
| Aluko | Bioactive lipids | |
| CA3069902A1 (en) | Compositions comprising thymoquinone and omega-3 fatty acids | |
| US20160113990A1 (en) | Herbal formulation of an edible oral turmeric, its derivatives & other ingredients for the management of inflammation and chronic pain | |
| Black | The role of nutritional lipids and antioxidants in UV-induced skin cancer | |
| US20200060322A1 (en) | Astaxanthin Nutritional Compositions And Uses | |
| JP6709847B2 (ja) | 非食物アレルギーを管理するためのペットフード組成物 | |
| WO2013086327A1 (en) | Nutritional compositions comprising curcumin and phosphatidylserine-docosahexaenoic acid for improving cognition | |
| Tolentino | Macular Supplements Containing Zinc and Vitamin A Should Be Replaced with Meso-Zeaxanthin, Lutein and Zeaxanthin: An Ophthalmic Need for Pharmacovigilance. J Pharmacovigil 4: 195. doi: 10.4172/2329-6887.1000195 Page 2 of 5 J Pharmacovigil ISSN: 2329-6887 JP an open access journal Volume 4• Issue 1• 1000195 | |
| Jaffe | Phytonutrients in diabetes management | |
| Lee | Pre-and co-treatment with xanthophyll enhances the anti-leukemic activity of adriamycin | |
| Tatlıparmak | Dietary Supplements in Dermatology Beside Hair and Nail Diseases |