JP2014501707A5 - - Google Patents
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- Publication number
- JP2014501707A5 JP2014501707A5 JP2013537210A JP2013537210A JP2014501707A5 JP 2014501707 A5 JP2014501707 A5 JP 2014501707A5 JP 2013537210 A JP2013537210 A JP 2013537210A JP 2013537210 A JP2013537210 A JP 2013537210A JP 2014501707 A5 JP2014501707 A5 JP 2014501707A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- cationic surfactant
- glucagon
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40972310P | 2010-11-03 | 2010-11-03 | |
| US40978510P | 2010-11-03 | 2010-11-03 | |
| US61/409,785 | 2010-11-03 | ||
| US61/409,723 | 2010-11-03 | ||
| US201161503104P | 2011-06-30 | 2011-06-30 | |
| US201161503178P | 2011-06-30 | 2011-06-30 | |
| US61/503,104 | 2011-06-30 | ||
| US61/503,178 | 2011-06-30 | ||
| PCT/GB2011/052139 WO2012059762A1 (en) | 2010-11-03 | 2011-11-03 | Novel composition comprising glucagon |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014501707A JP2014501707A (ja) | 2014-01-23 |
| JP2014501707A5 true JP2014501707A5 (enExample) | 2014-12-04 |
| JP5894174B2 JP5894174B2 (ja) | 2016-03-23 |
Family
ID=44913349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537210A Expired - Fee Related JP5894174B2 (ja) | 2010-11-03 | 2011-11-03 | グルカゴンを含む新規組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9023985B2 (enExample) |
| EP (1) | EP2635296B1 (enExample) |
| JP (1) | JP5894174B2 (enExample) |
| CA (1) | CA2816114C (enExample) |
| ES (1) | ES2533601T3 (enExample) |
| WO (2) | WO2012059764A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| PT2934568T (pt) | 2012-12-21 | 2018-01-04 | Sanofi Sa | Agonistas duplos de glp1/gip ou trigonais de glp1/gip/glucagina |
| US9254332B2 (en) | 2013-03-15 | 2016-02-09 | Arecor Limited | Stable aqueous formulations of adenovirus vectors |
| TW201609796A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 非醯化之艾塞那肽-4(exendin-4)胜肽類似物 |
| TW201609799A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/gip受體促效劑 |
| TW201609795A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 作為雙重glp-1/gip受體促效劑的艾塞那肽-4(exendin-4)胜肽類似物 |
| TW201609797A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| WO2016077220A1 (en) * | 2014-11-10 | 2016-05-19 | Mb2 Llc | Gip/glp-1 co-agonist peptides for human administration |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物 |
| CN107949374B (zh) * | 2015-09-04 | 2022-04-08 | 莱迪杜德制药公司 | 稳定的胰高血糖素溶液 |
| US11590205B2 (en) | 2015-09-25 | 2023-02-28 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents |
| KR20190026748A (ko) | 2016-06-07 | 2019-03-13 | 아도시아 | 인간 글루카곤 및 말단-그래프트된 코폴리아미노산을 포함하는 주사가능한 수용액 형태의 조성물 |
| GB201611077D0 (en) | 2016-06-24 | 2016-08-10 | Arecor Ltd | Novel composition |
| CA3084700A1 (en) | 2017-12-07 | 2019-06-13 | Adocia | Compositions in the form of an injectable aqueous solution comprising human glucagon and a copolyamino acid |
| WO2019110837A1 (fr) | 2017-12-07 | 2019-06-13 | Adocia | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide |
| US20190275110A1 (en) | 2017-12-07 | 2019-09-12 | Adocia | Compositions in the form of an injectale aqueous solution comprising human glucagon and a co-polyamino acid |
| EP3731858A1 (fr) * | 2017-12-07 | 2020-11-04 | Adocia | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide |
| FR3083087A1 (fr) | 2018-06-29 | 2020-01-03 | Adocia | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide |
| FR3067247A1 (fr) | 2018-06-07 | 2018-12-14 | Adocia | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide |
| IL298396A (en) * | 2020-05-22 | 2023-01-01 | Hanmi Pharm Ind Co Ltd | Liquid formulation of long-acting conjugate of glucagon derivative |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1202607A (en) * | 1968-01-10 | 1970-08-19 | Novo Terapeutisk Labor As | Improvements in or relating to stable glucagon solutions and their preparation |
| JPH0651637B2 (ja) | 1985-03-28 | 1994-07-06 | エーザイ株式会社 | ペプタイドの吸着防止組成物 |
| JP2001507722A (ja) * | 1997-11-06 | 2001-06-12 | オーボン コーポレイション | 薬物送達のための安定化乾燥薬学的組成物、およびそれを調製する方法 |
| WO1999047160A1 (en) | 1998-03-13 | 1999-09-23 | Novo Nordisk A/S | Stabilized aqueous peptide solutions |
| DK1093370T3 (da) * | 1998-06-30 | 2006-05-22 | Takeda Pharmaceutical | Farmaceutisk præparat til behandling af diabetes |
| JP2007204498A (ja) * | 1999-03-01 | 2007-08-16 | Chugai Pharmaceut Co Ltd | 長期安定化製剤 |
| JP4147234B2 (ja) * | 2004-09-27 | 2008-09-10 | キヤノン株式会社 | 吐出用液体、吐出方法、カートリッジ及び吐出装置 |
| US7115791B2 (en) | 2002-12-19 | 2006-10-03 | Exxonmobil Chemical Patents Inc. | Method and apparatus for controlling effluent composition in oxygenates to olefins conversion |
| JP2008505087A (ja) | 2004-06-29 | 2008-02-21 | ディオベックス, インコーポレイテッド | インスリン誘発性低血糖の予防および制御のための組成物ならびに方法 |
| WO2007056362A2 (en) | 2005-11-07 | 2007-05-18 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting physiological solubility and stability |
| CA2674354A1 (en) | 2007-01-05 | 2008-07-17 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting enhanced solubility in physiological ph buffers |
| GB0700523D0 (en) | 2007-01-11 | 2007-02-21 | Insense Ltd | The Stabilisation Of Proteins |
| EA017849B1 (ru) | 2007-02-15 | 2013-03-29 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Соагонисты глюкагоновых/glp-1-рецепторов |
| US20100184675A1 (en) * | 2007-09-11 | 2010-07-22 | Dorian Bevec | Use of glucagon (1-29) alone or in combination with neuropeptide w30 as a therapeutic agent |
| AU2008318986B2 (en) | 2007-10-30 | 2014-12-04 | Indiana University Research And Technology Corporation | Glucagon antagonists |
| WO2009058734A1 (en) | 2007-10-30 | 2009-05-07 | Indiana University Research And Technology Corporation | Compounds exhibiting glucagon antagonist and glp-1 agonist activity |
| JP2011511778A (ja) | 2008-01-30 | 2011-04-14 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーション | エステルに基づいたペプチドプロドラッグ |
| EA020326B9 (ru) | 2008-06-17 | 2015-03-31 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Агонисты смешанного действия на основе глюкозозависимого инсулинотропного пептида для лечения нарушений обмена веществ и ожирения |
| PA8830501A1 (es) | 2008-06-17 | 2010-07-27 | Univ Indiana Res & Tech Corp | Co-agonistas del receptor de glucagon/glp-1 |
| US8450270B2 (en) | 2008-06-17 | 2013-05-28 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting enhanced solubility and stability in physiological pH buffers |
| US20110097386A1 (en) * | 2009-10-22 | 2011-04-28 | Biodel, Inc. | Stabilized glucagon solutions |
| DK2490708T3 (da) | 2009-10-22 | 2013-04-15 | Biodel Inc | Stabiliserede glucagon-opløsninger |
-
2011
- 2011-11-03 CA CA2816114A patent/CA2816114C/en active Active
- 2011-11-03 EP EP11779842.1A patent/EP2635296B1/en not_active Not-in-force
- 2011-11-03 WO PCT/GB2011/052141 patent/WO2012059764A1/en not_active Ceased
- 2011-11-03 JP JP2013537210A patent/JP5894174B2/ja not_active Expired - Fee Related
- 2011-11-03 WO PCT/GB2011/052139 patent/WO2012059762A1/en not_active Ceased
- 2011-11-03 ES ES11779842.1T patent/ES2533601T3/es active Active
-
2013
- 2013-03-15 US US13/834,313 patent/US9023985B2/en active Active
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