JP2014501707A5 - - Google Patents
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- Publication number
- JP2014501707A5 JP2014501707A5 JP2013537210A JP2013537210A JP2014501707A5 JP 2014501707 A5 JP2014501707 A5 JP 2014501707A5 JP 2013537210 A JP2013537210 A JP 2013537210A JP 2013537210 A JP2013537210 A JP 2013537210A JP 2014501707 A5 JP2014501707 A5 JP 2014501707A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- cationic surfactant
- glucagon
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40978510P | 2010-11-03 | 2010-11-03 | |
| US40972310P | 2010-11-03 | 2010-11-03 | |
| US61/409,723 | 2010-11-03 | ||
| US61/409,785 | 2010-11-03 | ||
| US201161503178P | 2011-06-30 | 2011-06-30 | |
| US201161503104P | 2011-06-30 | 2011-06-30 | |
| US61/503,178 | 2011-06-30 | ||
| US61/503,104 | 2011-06-30 | ||
| PCT/GB2011/052139 WO2012059762A1 (en) | 2010-11-03 | 2011-11-03 | Novel composition comprising glucagon |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014501707A JP2014501707A (ja) | 2014-01-23 |
| JP2014501707A5 true JP2014501707A5 (enExample) | 2014-12-04 |
| JP5894174B2 JP5894174B2 (ja) | 2016-03-23 |
Family
ID=44913349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537210A Expired - Fee Related JP5894174B2 (ja) | 2010-11-03 | 2011-11-03 | グルカゴンを含む新規組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9023985B2 (enExample) |
| EP (1) | EP2635296B1 (enExample) |
| JP (1) | JP5894174B2 (enExample) |
| CA (1) | CA2816114C (enExample) |
| ES (1) | ES2533601T3 (enExample) |
| WO (2) | WO2012059762A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| WO2014096149A1 (en) | 2012-12-21 | 2014-06-26 | Sanofi | Exendin-4 Derivatives |
| US9254332B2 (en) | 2013-03-15 | 2016-02-09 | Arecor Limited | Stable aqueous formulations of adenovirus vectors |
| WO2015086730A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Non-acylated exendin-4 peptide analogues |
| WO2015086729A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/gip receptor agonists |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| TW201609795A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 作為雙重glp-1/gip受體促效劑的艾塞那肽-4(exendin-4)胜肽類似物 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| WO2016077220A1 (en) * | 2014-11-10 | 2016-05-19 | Mb2 Llc | Gip/glp-1 co-agonist peptides for human administration |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物 |
| CN107949374B (zh) * | 2015-09-04 | 2022-04-08 | 莱迪杜德制药公司 | 稳定的胰高血糖素溶液 |
| US11590205B2 (en) | 2015-09-25 | 2023-02-28 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents |
| EP3463295B1 (fr) | 2016-06-07 | 2020-08-05 | Adocia | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacidegreffe en bout de chaine |
| GB201611077D0 (en) | 2016-06-24 | 2016-08-10 | Arecor Ltd | Novel composition |
| WO2019110837A1 (fr) | 2017-12-07 | 2019-06-13 | Adocia | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide |
| WO2019110838A1 (fr) | 2017-12-07 | 2019-06-13 | Adocia | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide |
| US10987426B2 (en) | 2017-12-07 | 2021-04-27 | Adocia | Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid |
| US11191812B2 (en) | 2017-12-07 | 2021-12-07 | Adocia | Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid |
| FR3083087A1 (fr) | 2018-06-29 | 2020-01-03 | Adocia | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide |
| FR3067247A1 (fr) | 2018-06-07 | 2018-12-14 | Adocia | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide |
| AU2021277116A1 (en) * | 2020-05-22 | 2023-02-02 | Hanmi Pharm. Co., Ltd. | Liquid formulation of long-acting conjugate of glucagon derivative |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1202607A (en) | 1968-01-10 | 1970-08-19 | Novo Terapeutisk Labor As | Improvements in or relating to stable glucagon solutions and their preparation |
| JPH0651637B2 (ja) | 1985-03-28 | 1994-07-06 | エーザイ株式会社 | ペプタイドの吸着防止組成物 |
| EP0966271A1 (en) * | 1997-11-06 | 1999-12-29 | Orbon Corporation | Stabilized, dry pharmaceutical compositions for drug delivery and methods of preparing same |
| WO1999047160A1 (en) | 1998-03-13 | 1999-09-23 | Novo Nordisk A/S | Stabilized aqueous peptide solutions |
| AU754740B2 (en) * | 1998-06-30 | 2002-11-21 | Takeda Chemical Industries Ltd. | Pharmaceutical composition for the treatment of diabetes |
| JP2007204498A (ja) * | 1999-03-01 | 2007-08-16 | Chugai Pharmaceut Co Ltd | 長期安定化製剤 |
| JP4147234B2 (ja) * | 2004-09-27 | 2008-09-10 | キヤノン株式会社 | 吐出用液体、吐出方法、カートリッジ及び吐出装置 |
| US7115791B2 (en) | 2002-12-19 | 2006-10-03 | Exxonmobil Chemical Patents Inc. | Method and apparatus for controlling effluent composition in oxygenates to olefins conversion |
| AU2005260025A1 (en) | 2004-06-29 | 2006-01-12 | Diobex, Inc. | Compositions and methods for the prevention and control of insulin-induced hypoglycemia |
| CN101534846B (zh) | 2005-11-07 | 2014-11-05 | 印第安纳大学研究及科技有限公司 | 显示生理学溶解性和稳定性的胰高血糖素类似物 |
| JP5890085B2 (ja) | 2007-01-05 | 2016-03-22 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | 生理学的pHの緩衝液中で向上した溶解度を示すグルカゴン類縁体 |
| GB0700523D0 (en) | 2007-01-11 | 2007-02-21 | Insense Ltd | The Stabilisation Of Proteins |
| KR20090119876A (ko) | 2007-02-15 | 2009-11-20 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 글루카곤/glp-1 수용체 공동-항진물질 |
| AU2008303948A1 (en) * | 2007-09-11 | 2009-04-02 | Mondobiotech Laboratories Ag | Use of the peptide Asn-Asp-Asp-Cys-Glu- Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu alone or in combination with the peptide Thr-Thr-Ser-Gln-Val- Arg-Pro-Arg as a therapeutic agent |
| EP2217701B9 (en) | 2007-10-30 | 2015-02-18 | Indiana University Research and Technology Corporation | Glucagon antagonists |
| AU2008318876B2 (en) | 2007-10-30 | 2014-05-15 | Indiana University Research And Technology Corporation | Compounds exhibiting glucagon antagonist and GLP-1 agonist activity |
| AU2009210570B2 (en) | 2008-01-30 | 2014-11-20 | Indiana University Research And Technology Corporation | Ester-based insulin prodrugs |
| CL2009001425A1 (es) | 2008-06-17 | 2010-04-30 | Univ Indiana Res & Tech Corp | Analogos de glucagon con un aminoacido aromatico grande que carece de cadena lateral de imidazol que le confiere actividad agonista del receptor gip; composiciones farmaceutica; kit que los contiene y uso para reducir el aumento de peso, tratar la diabetes o inducir paralisis del tracto intestinal. |
| EP2307037A4 (en) | 2008-06-17 | 2011-08-03 | Univ Indiana Res & Tech Corp | GLUCAGON ANALOGUE WITH IMPROVED SOLUBILITY AND STABILITY IN PHYSIOLOGICAL PH BUFFERS |
| NZ589847A (en) | 2008-06-17 | 2013-01-25 | Univ Indiana Res & Tech Corp | Glucagon/glp-1 receptor co-agonists |
| EP2490708B1 (en) | 2009-10-22 | 2013-03-27 | Biodel Inc. | Stabilized glucagon solutions |
| US20110097386A1 (en) * | 2009-10-22 | 2011-04-28 | Biodel, Inc. | Stabilized glucagon solutions |
-
2011
- 2011-11-03 WO PCT/GB2011/052139 patent/WO2012059762A1/en not_active Ceased
- 2011-11-03 JP JP2013537210A patent/JP5894174B2/ja not_active Expired - Fee Related
- 2011-11-03 WO PCT/GB2011/052141 patent/WO2012059764A1/en not_active Ceased
- 2011-11-03 ES ES11779842.1T patent/ES2533601T3/es active Active
- 2011-11-03 CA CA2816114A patent/CA2816114C/en active Active
- 2011-11-03 EP EP11779842.1A patent/EP2635296B1/en not_active Not-in-force
-
2013
- 2013-03-15 US US13/834,313 patent/US9023985B2/en active Active
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