JP2014133739A - インダゾール誘導体またはピロロピリジン誘導体からなる医薬 - Google Patents
インダゾール誘導体またはピロロピリジン誘導体からなる医薬 Download PDFInfo
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- JP2014133739A JP2014133739A JP2013256668A JP2013256668A JP2014133739A JP 2014133739 A JP2014133739 A JP 2014133739A JP 2013256668 A JP2013256668 A JP 2013256668A JP 2013256668 A JP2013256668 A JP 2013256668A JP 2014133739 A JP2014133739 A JP 2014133739A
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- 0 CC*(C)c1c(C)c(C)c(C)c2c1C(*(C)(CC)CC)=**2[Zn] Chemical compound CC*(C)c1c(C)c(C)c(C)c2c1C(*(C)(CC)CC)=**2[Zn] 0.000 description 9
- SPURNXOZTCISSS-UHFFFAOYSA-N CC(C)(C)OC(N(CC1)CCC1N(CC1)CCC1c1nc(-[n](c2c3cccc2F)nc3I)n[o]1)=O Chemical compound CC(C)(C)OC(N(CC1)CCC1N(CC1)CCC1c1nc(-[n](c2c3cccc2F)nc3I)n[o]1)=O SPURNXOZTCISSS-UHFFFAOYSA-N 0.000 description 1
- HUIQEAWUEGAXRA-UHFFFAOYSA-N CC(C)(C)OC(N(CC1)CCC1N(CC1)CCC1c1nc(-[n]2nc(C3CC3)c3cccc(F)c23)n[o]1)=O Chemical compound CC(C)(C)OC(N(CC1)CCC1N(CC1)CCC1c1nc(-[n]2nc(C3CC3)c3cccc(F)c23)n[o]1)=O HUIQEAWUEGAXRA-UHFFFAOYSA-N 0.000 description 1
- OJCLHERKFHHUTB-UHFFFAOYSA-N CC(C)(C)OC(N1CC(CO)CCC1)=O Chemical compound CC(C)(C)OC(N1CC(CO)CCC1)=O OJCLHERKFHHUTB-UHFFFAOYSA-N 0.000 description 1
- PCJCYWZFDBHLGN-UHFFFAOYSA-N CC(C)(C)c1n[nH]c2ccccc12 Chemical compound CC(C)(C)c1n[nH]c2ccccc12 PCJCYWZFDBHLGN-UHFFFAOYSA-N 0.000 description 1
- BRTJWPTTXMCOLH-UHFFFAOYSA-N CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C2CCCCC2)n1 Chemical compound CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C2CCCCC2)n1 BRTJWPTTXMCOLH-UHFFFAOYSA-N 0.000 description 1
- CQDZNIXYGZHACI-UHFFFAOYSA-N CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C2CCN(CC(CC3)CN3C(CO)=O)CC2)n1 Chemical compound CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C2CCN(CC(CC3)CN3C(CO)=O)CC2)n1 CQDZNIXYGZHACI-UHFFFAOYSA-N 0.000 description 1
- BVMLTMPOVCMWCD-HNNXBMFYSA-N CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C2CCN(C[C@@H]3CNCC3)CC2)n1 Chemical compound CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C2CCN(C[C@@H]3CNCC3)CC2)n1 BVMLTMPOVCMWCD-HNNXBMFYSA-N 0.000 description 1
- AXBGWWFDOCXULF-MRXNPFEDSA-N CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C[C@@H](CC2)CN2C2CCCCC2)n1 Chemical compound CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C[C@@H](CC2)CN2C2CCCCC2)n1 AXBGWWFDOCXULF-MRXNPFEDSA-N 0.000 description 1
- XTDSAACDVQJULK-JTGIGXABSA-N CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C[C@@H]2CN(C[C@@H]3CCC(CC(COC)=O)CCC3)CC2)n1 Chemical compound CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C[C@@H]2CN(C[C@@H]3CCC(CC(COC)=O)CCC3)CC2)n1 XTDSAACDVQJULK-JTGIGXABSA-N 0.000 description 1
- AXBGWWFDOCXULF-INIZCTEOSA-N CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C[C@H](CC2)CN2C2CCCCC2)n1 Chemical compound CC(C)c(c1cccc(F)c11)n[n]1-c1n[o]c(C[C@H](CC2)CN2C2CCCCC2)n1 AXBGWWFDOCXULF-INIZCTEOSA-N 0.000 description 1
- DWPMJTVAEDBIES-UHFFFAOYSA-N CC(CC1)CCN1C(C)=O Chemical compound CC(CC1)CCN1C(C)=O DWPMJTVAEDBIES-UHFFFAOYSA-N 0.000 description 1
- UALMQZFSSLRDAE-UHFFFAOYSA-N CC(N(CC1)CCC1N(CC1)CCC1C(O)=O)=O Chemical compound CC(N(CC1)CCC1N(CC1)CCC1C(O)=O)=O UALMQZFSSLRDAE-UHFFFAOYSA-N 0.000 description 1
- URUDFIJGIUFEED-UHFFFAOYSA-N CCCCC(CCC)c1nc(-[n]2nc(C(C)C)c3cccc(F)c23)n[o]1 Chemical compound CCCCC(CCC)c1nc(-[n]2nc(C(C)C)c3cccc(F)c23)n[o]1 URUDFIJGIUFEED-UHFFFAOYSA-N 0.000 description 1
- SFZWHYPFUKYFLL-UHFFFAOYSA-N CCCN(C1)CC1c1nc(-[n]2nc(CC)c3ccccc23)n[o]1 Chemical compound CCCN(C1)CC1c1nc(-[n]2nc(CC)c3ccccc23)n[o]1 SFZWHYPFUKYFLL-UHFFFAOYSA-N 0.000 description 1
- JXFJPBJXGKRNOK-UHFFFAOYSA-N CCc(c(c1c2)ccc2F)n[n]1-c1n[o]c(C2CCNCC2)n1 Chemical compound CCc(c(c1c2)ccc2F)n[n]1-c1n[o]c(C2CCNCC2)n1 JXFJPBJXGKRNOK-UHFFFAOYSA-N 0.000 description 1
- XYXXNTSJPOTJPD-UHFFFAOYSA-N CCc(c(cc1)c2cc1F)n[n]2-c1n[o]c(C2CCN(CC3CCOCC3)CC2)n1 Chemical compound CCc(c(cc1)c2cc1F)n[n]2-c1n[o]c(C2CCN(CC3CCOCC3)CC2)n1 XYXXNTSJPOTJPD-UHFFFAOYSA-N 0.000 description 1
- IGDOLCACXZLYBZ-UHFFFAOYSA-N CCc(c1ccccc11)n[n]1-c1n[o]c(C2CCN(CC(CCC3)CN3SCC)CC2)n1 Chemical compound CCc(c1ccccc11)n[n]1-c1n[o]c(C2CCN(CC(CCC3)CN3SCC)CC2)n1 IGDOLCACXZLYBZ-UHFFFAOYSA-N 0.000 description 1
- PAHBGNDQLCNTGJ-UHFFFAOYSA-N CCc(c1ccccc11)n[n]1-c1n[o]c(C2CNC2)n1 Chemical compound CCc(c1ccccc11)n[n]1-c1n[o]c(C2CNC2)n1 PAHBGNDQLCNTGJ-UHFFFAOYSA-N 0.000 description 1
- GGQPLRWNPUULGB-UHFFFAOYSA-N COc1n[n](/C(/N)=N\O)c2c1cccc2F Chemical compound COc1n[n](/C(/N)=N\O)c2c1cccc2F GGQPLRWNPUULGB-UHFFFAOYSA-N 0.000 description 1
- PJVUHCMSXCKBPA-UHFFFAOYSA-O CS([OH2+])(OCC(CCC1)CN1S=O)=O Chemical compound CS([OH2+])(OCC(CCC1)CN1S=O)=O PJVUHCMSXCKBPA-UHFFFAOYSA-O 0.000 description 1
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- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013256668A JP2014133739A (ja) | 2012-12-12 | 2013-12-12 | インダゾール誘導体またはピロロピリジン誘導体からなる医薬 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012271099 | 2012-12-12 | ||
| JP2012271099 | 2012-12-12 | ||
| JP2013256668A JP2014133739A (ja) | 2012-12-12 | 2013-12-12 | インダゾール誘導体またはピロロピリジン誘導体からなる医薬 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014133739A true JP2014133739A (ja) | 2014-07-24 |
| JP2014133739A5 JP2014133739A5 (https=) | 2015-01-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013256668A Pending JP2014133739A (ja) | 2012-12-12 | 2013-12-12 | インダゾール誘導体またはピロロピリジン誘導体からなる医薬 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2014133739A (https=) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9545405B2 (en) | 2013-02-22 | 2017-01-17 | Pfizer Inc. | Pyrrolo[2,3-D]pyrimidine derivatives |
| US10328053B2 (en) | 2016-08-26 | 2019-06-25 | Gilead Sciences, Inc. | Substituted pyrrolizine compounds and uses thereof |
| US10836769B2 (en) | 2018-02-26 | 2020-11-17 | Gilead Sciences, Inc. | Substituted pyrrolizine compounds and uses thereof |
| US10966980B2 (en) | 2014-08-12 | 2021-04-06 | Pfizer Inc. | Pyrrolo[2,3-d]pyrimidine derivatives |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| CN115417772A (zh) * | 2022-09-26 | 2022-12-02 | 无锡双启科技有限公司 | 一种3-硝基-4-氟苯甲醚的制备方法 |
| WO2025045837A1 (en) | 2023-08-31 | 2025-03-06 | Syngenta Crop Protection Ag | Pesticidally active indazole compounds |
| US12577240B2 (en) | 2020-07-11 | 2026-03-17 | Pfizer Inc. | Antiviral heteroaryl ketone derivatives |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050197335A1 (en) * | 2004-02-18 | 2005-09-08 | Daniel Marquess | Indazole-carboxamide compounds as 5-HT4 receptor agonists |
| JP2006505544A (ja) * | 2002-09-25 | 2006-02-16 | ワイス | エストロゲン受容体(er)配位子としての置換4−(インダゾール−3−イル)フェノール及び炎症疾患治療におけるそれらの使用 |
| US20060135764A1 (en) * | 2004-12-22 | 2006-06-22 | Theravance, Inc. | Indazole-carboxamide compounds |
| JP2009543836A (ja) * | 2006-07-14 | 2009-12-10 | グラクソ グループ リミテッド | インドール化合物 |
| WO2012069917A1 (en) * | 2010-11-26 | 2012-05-31 | Lupin Limited | Bicyclic gpr119 modulators |
-
2013
- 2013-12-12 JP JP2013256668A patent/JP2014133739A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006505544A (ja) * | 2002-09-25 | 2006-02-16 | ワイス | エストロゲン受容体(er)配位子としての置換4−(インダゾール−3−イル)フェノール及び炎症疾患治療におけるそれらの使用 |
| US20050197335A1 (en) * | 2004-02-18 | 2005-09-08 | Daniel Marquess | Indazole-carboxamide compounds as 5-HT4 receptor agonists |
| US20060135764A1 (en) * | 2004-12-22 | 2006-06-22 | Theravance, Inc. | Indazole-carboxamide compounds |
| JP2009543836A (ja) * | 2006-07-14 | 2009-12-10 | グラクソ グループ リミテッド | インドール化合物 |
| WO2012069917A1 (en) * | 2010-11-26 | 2012-05-31 | Lupin Limited | Bicyclic gpr119 modulators |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9549929B2 (en) | 2013-02-22 | 2017-01-24 | Pfizer Inc. | Pyrrolo[2,3-D]pyrimidine derivatives |
| US9545405B2 (en) | 2013-02-22 | 2017-01-17 | Pfizer Inc. | Pyrrolo[2,3-D]pyrimidine derivatives |
| US10966980B2 (en) | 2014-08-12 | 2021-04-06 | Pfizer Inc. | Pyrrolo[2,3-d]pyrimidine derivatives |
| US12161625B2 (en) | 2016-08-26 | 2024-12-10 | Gilead Sciences, Inc. | Substituted pyrrolizine compounds and uses thereof |
| US10328053B2 (en) | 2016-08-26 | 2019-06-25 | Gilead Sciences, Inc. | Substituted pyrrolizine compounds and uses thereof |
| US10874640B2 (en) | 2016-08-26 | 2020-12-29 | Gilead Sciences, Inc. | Substituted pyrrolizine compounds and uses thereof |
| US10836769B2 (en) | 2018-02-26 | 2020-11-17 | Gilead Sciences, Inc. | Substituted pyrrolizine compounds and uses thereof |
| US11420974B2 (en) | 2018-02-26 | 2022-08-23 | Gilead Sciences, Inc. | Substituted pyrrolizine compounds and uses thereof |
| US12577240B2 (en) | 2020-07-11 | 2026-03-17 | Pfizer Inc. | Antiviral heteroaryl ketone derivatives |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| US11541034B2 (en) | 2020-09-03 | 2023-01-03 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| US11452711B2 (en) | 2020-09-03 | 2022-09-27 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| CN115417772A (zh) * | 2022-09-26 | 2022-12-02 | 无锡双启科技有限公司 | 一种3-硝基-4-氟苯甲醚的制备方法 |
| WO2025045837A1 (en) | 2023-08-31 | 2025-03-06 | Syngenta Crop Protection Ag | Pesticidally active indazole compounds |
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