JP2014058541A5 - - Google Patents
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- JP2014058541A5 JP2014058541A5 JP2013238416A JP2013238416A JP2014058541A5 JP 2014058541 A5 JP2014058541 A5 JP 2014058541A5 JP 2013238416 A JP2013238416 A JP 2013238416A JP 2013238416 A JP2013238416 A JP 2013238416A JP 2014058541 A5 JP2014058541 A5 JP 2014058541A5
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- Japan
- Prior art keywords
- composition
- polypeptide
- subject
- aaq66654
- immune response
- Prior art date
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Claims (14)
- 被験体におけるポルフィロモナス・ジンジバリスに対する免疫応答を生じさせる際に使用する組成物であって、免疫応答を生じさせるための有効量の、ＡＡＱ６６６５４、ＡＡＱ６５７４２、ＡＡＱ６６９９１、ＡＡＱ６５５６１、ＡＡＱ６６８３１、ＡＡＱ６６７９７、ＡＡＱ６６４６９、ＡＡＱ６６５８７、ＡＡＱ６６９７７、ＡＡＱ６５７９７、ＡＡＱ６５８６７、ＡＡＱ６５８６８、ＡＡＱ６５４１６、ＡＡＱ６５４４９、ＡＡＱ６６０５１、ＡＡＱ６６３７７、ＡＡＱ６６４４４、ＡＡＱ６６５３８、ＡＡＱ６７１１７及びＡＡＱ６７１１８から成る群から選択されるアクセッション番号に対応するポリペプチドの、少なくとも１つの抗原性部分又は免疫原性部分を含む、組成物。
- 前記部分が、前記ポリペプチドの１つの少なくとも５０個のアミノ酸と実質的に同一であるアミノ酸配列を有する、請求項１に記載の組成物。
- 前記ポリペプチドが、ＡＡＱ６６６５４、ＡＡＱ６６９９１、ＡＡＱ６５５６１及びＡＡＱ６６８３１から成る群から選択されるアクセッション番号に対応する、請求項１又は２に記載の組成物。
- 前記ポリペプチドがアクセッション番号ＡＡＱ６６６５４に対応する、請求項１又は２に記載の組成物。
- 被験体におけるポルフィロモナス・ジンジバリスに対する免疫応答を生じさせる際に使用する組成物であって、免疫応答を生じさせるための有効量の、ポルフィロモナス・ジンジバリスにより発現され、且つＣＥＬＬＯプログラムにより細胞外にあることが予測されるポリペプチドの少なくとも５０個のアミノ酸と実質的に同一であるアミノ酸配列を有する少なくとも１つのポリペプチドを含む、組成物。
- 被験体におけるポルフィロモナス・ジンジバリスに対する免疫応答を生じさせる際に使用する組成物であって、免疫応答を生じさせるための有効量の、マウス又はウサギにおいて免疫応答を引き起こすポリペプチドの少なくとも５０個のアミノ酸と実質的に同一である選択されたアミノ酸配列を有する少なくとも１つのポリペプチドを含む、組成物。
- 被験体を歯周病に関して防止、抑制又は治療するための薬学的組成物であって、有効量の、請求項１〜６のいずれか一項に記載の組成物を含む、薬学的組成物。
- 被験体をポルフィロモナス・ジンジバリス感染症に関して防止又は治療するための薬学的組成物であって、請求項１〜７のいずれか一項に記載の組成物を含む、薬学的組成物。
- アクセッション番号ＡＡＱ６６６５４、ＡＡＱ６５７４２、ＡＡＱ６６９９１、ＡＡＱ６５５６１、ＡＡＱ６６８３１、ＡＡＱ６６７９７、ＡＡＱ６６４６９、ＡＡＱ６６５８７、ＡＡＱ６６９７７、ＡＡＱ６５７９７、ＡＡＱ６５８６７、ＡＡＱ６５８６８、ＡＡＱ６５４１６、ＡＡＱ６５４４９、ＡＡＱ６６０５１、ＡＡＱ６６３７７、ＡＡＱ６６４４４、ＡＡＱ６６５３８、ＡＡＱ６７１１７及びＡＡＱ６７１１８に対応するポリペプチドの１つの少なくとも５０個のアミノ酸と実質的に同一であるアミノ酸配列を有する、該ポリペプチドの抗原性領域に対して産生される抗体。
- 前記ポリペプチドが、ＡＡＱ６６６５４、ＡＡＱ６６９９１、ＡＡＱ６５５６１及びＡＡＱ６６８３１から成る群から選択されるアクセッション番号に対応する、請求項９に記載の抗体。
- 前記ポリペプチドがアクセッション番号ＡＡＱ６６６５４に対応する、請求項９に記載の抗体。
- ポルフィロモナス・ジンジバリス感染症又は歯周病を、それを必要としている被検体において治療又は予防するための薬物の製造における、請求項１〜６のいずれか１項に記載の組成物の使用。
- ポルフィロモナス・ジンジバリス感染症又は歯周病を、それを必要としている被検体において治療又は予防するための薬物の製造における、請求項９〜１１のいずれか１項に記載の抗体の使用。
- ポルフィロモナス・ジンジバリス感染症又は歯周病を、それを必要としている被検体において治療又は予防するための薬物の製造における、アクセッション番号ＡＡＱ６６６５４に対応するポリペプチドの、少なくとも１つの抗原性部分又は免疫原性部分の使用。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2007903787 | 2007-07-12 | ||
| AU2007903787A AU2007903787A0 (en) | 2007-07-12 | Immunology treatment for biofilms |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515320A Division JP2010532766A (ja) | 2007-07-12 | 2008-07-11 | バイオフィルムに対する免疫学的治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014058541A JP2014058541A (ja) | 2014-04-03 |
| JP2014058541A5 true JP2014058541A5 (ja) | 2014-05-15 |
Family
ID=40228121
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515320A Pending JP2010532766A (ja) | 2007-07-12 | 2008-07-11 | バイオフィルムに対する免疫学的治療 |
| JP2013238416A Pending JP2014058541A (ja) | 2007-07-12 | 2013-11-19 | バイオフィルムに対する免疫学的治療 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515320A Pending JP2010532766A (ja) | 2007-07-12 | 2008-07-11 | バイオフィルムに対する免疫学的治療 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20100297179A1 (ja) |
| EP (2) | EP2176413A4 (ja) |
| JP (2) | JP2010532766A (ja) |
| KR (1) | KR20100071964A (ja) |
| CN (2) | CN101842486A (ja) |
| AU (1) | AU2008274907B2 (ja) |
| CA (1) | CA2693717A1 (ja) |
| NZ (3) | NZ582438A (ja) |
| SG (1) | SG182988A1 (ja) |
| WO (1) | WO2009006700A1 (ja) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO652897A0 (en) | 1997-04-30 | 1997-05-29 | University Of Melbourne, The | Synthetic peptide constructs for the diagnosis and treatment of periodontitis |
| US8129500B2 (en) * | 1997-12-10 | 2012-03-06 | Csl Limited | Porphyromonas gingivalis polypeptides and nucleotides |
| CA2652957A1 (en) | 2006-06-27 | 2008-01-03 | Oral Health Australia Pty Ltd. | Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease |
| WO2009006699A1 (en) * | 2007-07-12 | 2009-01-15 | Oral Health Australia Pty Ltd | Biofilm treatment |
| CN107266582B (zh) | 2008-08-29 | 2021-09-10 | 口腔健康澳洲私人有限公司 | 牙龈卟啉单胞菌感染的预防、治疗和诊断 |
| CA2769231A1 (en) * | 2009-08-02 | 2011-02-10 | Sanofi Pasteur Limited | Porphyromonas gingivalis polypeptides |
| US8140041B2 (en) * | 2009-08-27 | 2012-03-20 | Mediatek Inc. | Tunable capacitive device with linearization technique employed therein |
| CN105418758A (zh) * | 2015-12-03 | 2016-03-23 | 沈阳惠民生物技术有限公司 | 一种抗牙周病抗体的制备方法及其应用 |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| CN113005069B (zh) * | 2021-01-28 | 2023-09-26 | 广东海洋大学 | 一种减毒鰤鱼诺卡氏菌及其制备方法和应用 |
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| US4837151A (en) * | 1980-05-19 | 1989-06-06 | The Board Of Trustees Of The Leland Stanford Junior University, Stanford University | Live vaccines comprising two mutations and foreign antigen |
| US4735801A (en) * | 1982-09-07 | 1988-04-05 | Board Of Trustees Of Leland Stanford Jr. University | Novel non-reverting salmonella live vaccines |
| US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
| US5830710A (en) | 1988-09-08 | 1998-11-03 | University Of Florida | Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease |
| WO1994027606A1 (en) | 1993-05-28 | 1994-12-08 | Unisearch Limited | Method of treating helicobacter pylori infection |
| AU6983594A (en) * | 1993-06-28 | 1995-01-17 | Lion Corporation | Composition for oral cavity |
| US6017532A (en) * | 1993-09-10 | 2000-01-25 | University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase |
| US5523390A (en) * | 1993-09-10 | 1996-06-04 | University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase |
| US5475097A (en) * | 1993-10-21 | 1995-12-12 | University Of Georgia Research Foundation, Inc. | Lysine-specific Porphyromonas gingivalis proteinase |
| EP0717747B1 (en) | 1993-09-10 | 2003-06-04 | The University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase coding sequences |
| JPH0797395A (ja) | 1993-09-28 | 1995-04-11 | Kyowa Medex Co Ltd | ポルフイロモナス・ジンジバリス線毛蛋白質の配列を含有するペプチド類及びその用途 |
| DE69527514T2 (de) | 1994-03-29 | 2003-04-03 | Kyowa Hakko Kogyo Co., Ltd. | Gen eines zelloberflächenpolypeptids |
| AUPN627595A0 (en) * | 1995-10-30 | 1995-11-23 | University Of Melbourne, The | Diagnostics and treatments of periodontal disease |
| EP0888124A4 (en) | 1996-03-22 | 2001-04-11 | Univ Georgia Res Found | IMMUNOGENIC COMPOSITIONS COMPRISING PORPHYROMONAS GINGIVALIS PEPTIDES AND METHODS |
| AUPN901296A0 (en) * | 1996-03-29 | 1996-04-26 | University Of Melbourne, The | Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis |
| US7341727B1 (en) * | 1996-05-03 | 2008-03-11 | Emergent Product Development Gaithersburg Inc. | M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same |
| AUPO652897A0 (en) * | 1997-04-30 | 1997-05-29 | University Of Melbourne, The | Synthetic peptide constructs for the diagnosis and treatment of periodontitis |
| AUPP083997A0 (en) * | 1997-12-10 | 1998-01-08 | Csl Limited | Porphyromonas gingivalis nucleotides |
| EP2264176A1 (en) * | 1997-12-10 | 2010-12-22 | CSL Limited | Porphorymonas gingivalis polypeptides and polynucleotides |
| US8129500B2 (en) * | 1997-12-10 | 2012-03-06 | Csl Limited | Porphyromonas gingivalis polypeptides and nucleotides |
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| AUPP893999A0 (en) * | 1999-03-01 | 1999-03-25 | Csl Limited | Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis |
| US7090973B1 (en) * | 1999-04-09 | 2006-08-15 | Oscient Pharmaceuticals Corporation | Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics |
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| JP2003192616A (ja) | 2001-12-27 | 2003-07-09 | Univ Nihon | 歯周病用ｄｎａワクチン |
| JP2003286191A (ja) | 2002-03-27 | 2003-10-07 | Univ Nihon | 歯周病用粘膜免疫ワクチン |
| US20070036734A1 (en) | 2003-03-17 | 2007-02-15 | Kirin Beer Kabushiki Kaisha | Therapeutic agent for periodontal disease |
| WO2005019249A2 (en) * | 2003-08-15 | 2005-03-03 | University Of Florida | Identification of porphyromonas gingivalis virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases |
| EP1721283B1 (en) * | 2004-02-06 | 2022-11-30 | Council of Scientific and Industrial Research | Computational method for identifying adhesin and adhesin-like proteins of therapeutic potential |
| US20090169568A1 (en) * | 2004-09-23 | 2009-07-02 | The University Of Melbourne | Antigenic Complex for the Diagnosis and Treatment of Porphyromonas Gingivalis Infection |
| WO2008016385A2 (en) * | 2006-01-20 | 2008-02-07 | The University Of Washington | Deacylase polypeptides, deacylase polynucleotides, and methods of use thereof |
| CA2652957A1 (en) * | 2006-06-27 | 2008-01-03 | Oral Health Australia Pty Ltd. | Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease |
| WO2008124646A2 (en) | 2007-04-06 | 2008-10-16 | The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services | Use of amyloid proteins as vaccine scaffolds |
| WO2009006699A1 (en) * | 2007-07-12 | 2009-01-15 | Oral Health Australia Pty Ltd | Biofilm treatment |
| JP2012530073A (ja) * | 2009-06-19 | 2012-11-29 | オーラル ヘルス オーストラリア ピーティーワイ リミテッド | カゼイン由来のプロテアーゼ阻害ペプチド |
-
2008
- 2008-07-11 EP EP08772644A patent/EP2176413A4/en not_active Withdrawn
- 2008-07-11 CA CA2693717A patent/CA2693717A1/en not_active Abandoned
- 2008-07-11 AU AU2008274907A patent/AU2008274907B2/en not_active Ceased
- 2008-07-11 WO PCT/AU2008/001018 patent/WO2009006700A1/en active Application Filing
- 2008-07-11 CN CN200880104633A patent/CN101842486A/zh active Pending
- 2008-07-11 NZ NZ582438A patent/NZ582438A/en not_active IP Right Cessation
- 2008-07-11 NZ NZ595378A patent/NZ595378A/xx not_active IP Right Cessation
- 2008-07-11 JP JP2010515320A patent/JP2010532766A/ja active Pending
- 2008-07-11 CN CN2012101357337A patent/CN102652831A/zh active Pending
- 2008-07-11 EP EP13152880.4A patent/EP2604692A1/en not_active Withdrawn
- 2008-07-11 NZ NZ605037A patent/NZ605037A/en not_active IP Right Cessation
- 2008-07-11 SG SG2012048872A patent/SG182988A1/en unknown
- 2008-07-11 KR KR1020107003307A patent/KR20100071964A/ko not_active Application Discontinuation
- 2008-07-11 US US12/668,407 patent/US20100297179A1/en not_active Abandoned
-
2012
- 2012-09-20 US US13/623,442 patent/US8911745B2/en not_active Expired - Fee Related
-
2013
- 2013-11-19 JP JP2013238416A patent/JP2014058541A/ja active Pending
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