JP2014015489A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014015489A5 JP2014015489A5 JP2013225889A JP2013225889A JP2014015489A5 JP 2014015489 A5 JP2014015489 A5 JP 2014015489A5 JP 2013225889 A JP2013225889 A JP 2013225889A JP 2013225889 A JP2013225889 A JP 2013225889A JP 2014015489 A5 JP2014015489 A5 JP 2014015489A5
- Authority
- JP
- Japan
- Prior art keywords
- ylthio
- dichlorobenzyl
- thiazol
- carboxymethyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000013078 crystal Substances 0.000 claims 5
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 238000000634 powder X-ray diffraction Methods 0.000 claims 3
- 125000006512 3,4-dichlorobenzyl group Chemical group [H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C([H])([H])* 0.000 claims 2
- 238000000113 differential scanning calorimetry Methods 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- 125000004312 morpholin-2-yl group Chemical group [H]N1C([H])([H])C([H])([H])OC([H])(*)C1([H])[H] 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 238000001228 spectrum Methods 0.000 claims 2
- QBXNXHODSIQDRT-AWEZNQCLSA-N 2-[2-[2-[[(2s)-4-[(3,4-dichlorophenyl)methyl]morpholin-2-yl]methylamino]-2-oxoethyl]sulfanyl-1,3-thiazol-4-yl]acetic acid Chemical compound OC(=O)CC1=CSC(SCC(=O)NC[C@@H]2OCCN(CC=3C=C(Cl)C(Cl)=CC=3)C2)=N1 QBXNXHODSIQDRT-AWEZNQCLSA-N 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 206010010744 Conjunctivitis allergic Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 208000003926 Myelitis Diseases 0.000 claims 1
- 206010039085 Rhinitis allergic Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 208000002205 allergic conjunctivitis Diseases 0.000 claims 1
- 230000000172 allergic effect Effects 0.000 claims 1
- 201000010105 allergic rhinitis Diseases 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 208000024998 atopic conjunctivitis Diseases 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000001938 differential scanning calorimetry curve Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 201000009890 sinusitis Diseases 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013225889A JP2014015489A (ja) | 2006-07-11 | 2013-10-30 | モルホリン化合物の塩 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006190437 | 2006-07-11 | ||
| JP2006190437 | 2006-07-11 | ||
| JP2013225889A JP2014015489A (ja) | 2006-07-11 | 2013-10-30 | モルホリン化合物の塩 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008524814A Division JP5501615B2 (ja) | 2006-07-11 | 2007-07-11 | モルホリン化合物の塩 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014015489A JP2014015489A (ja) | 2014-01-30 |
| JP2014015489A5 true JP2014015489A5 (enExample) | 2014-03-20 |
Family
ID=38923247
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008524814A Expired - Fee Related JP5501615B2 (ja) | 2006-07-11 | 2007-07-11 | モルホリン化合物の塩 |
| JP2013225889A Pending JP2014015489A (ja) | 2006-07-11 | 2013-10-30 | モルホリン化合物の塩 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008524814A Expired - Fee Related JP5501615B2 (ja) | 2006-07-11 | 2007-07-11 | モルホリン化合物の塩 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8030303B2 (enExample) |
| EP (1) | EP2042499B1 (enExample) |
| JP (2) | JP5501615B2 (enExample) |
| ES (1) | ES2687756T3 (enExample) |
| TW (1) | TWI399375B (enExample) |
| WO (1) | WO2008007691A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8030303B2 (en) * | 2006-07-11 | 2011-10-04 | Mitsubishi Tanabe Pharma Corporation | Salt of morpholine compound |
| US10130634B2 (en) | 2013-07-24 | 2018-11-20 | Mitsubishi Tanabe Pharma Corporation | Therapeutic agent for ophthalmic disease |
| WO2020203822A1 (ja) * | 2019-03-29 | 2020-10-08 | 千寿製薬株式会社 | 血管新生を伴う網膜疾患の治療又は予防のための併用医薬 |
| US20230312697A1 (en) | 2020-06-11 | 2023-10-05 | Alkahest Inc. | Methods of improving retina-associated disease outcome using ccr3-inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005097120A (ja) | 2000-10-06 | 2005-04-14 | Mochida Pharmaceut Co Ltd | ４−ヒドロキシピペリジン誘導体の非潮解性塩 |
| MEP5808A (xx) * | 2002-12-23 | 2010-02-10 | Lundbeck & Co As H | Ecitalopram bromhidrat i postupak za njegovo pripremanje |
| IN2014CN03493A (enExample) * | 2004-09-08 | 2015-07-03 | Mitsubishi Tanabe Pharma Corp | |
| KR101137880B1 (ko) | 2004-12-31 | 2012-04-20 | 엘지디스플레이 주식회사 | 쉬프트 레지스터 및 그 구동 방법 |
| US8030303B2 (en) * | 2006-07-11 | 2011-10-04 | Mitsubishi Tanabe Pharma Corporation | Salt of morpholine compound |
-
2007
- 2007-07-11 US US12/309,196 patent/US8030303B2/en not_active Expired - Fee Related
- 2007-07-11 EP EP07790605.5A patent/EP2042499B1/en not_active Not-in-force
- 2007-07-11 WO PCT/JP2007/063801 patent/WO2008007691A1/ja not_active Ceased
- 2007-07-11 ES ES07790605.5T patent/ES2687756T3/es active Active
- 2007-07-11 JP JP2008524814A patent/JP5501615B2/ja not_active Expired - Fee Related
- 2007-07-11 TW TW096125165A patent/TWI399375B/zh not_active IP Right Cessation
-
2013
- 2013-10-30 JP JP2013225889A patent/JP2014015489A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013237682A5 (enExample) | ||
| JP2015500331A5 (enExample) | ||
| JP2017526711A5 (enExample) | ||
| JP2014526498A5 (enExample) | ||
| JP2018024682A5 (enExample) | ||
| JP2017527578A5 (enExample) | ||
| JP2014015489A5 (enExample) | ||
| HRP20210388T4 (hr) | Kristalni polimorf slobodne baze od 2-hidroksi-6-((2-(1-izopropil-1h-pirazol-5-il)piridin-3-il)metoksi)benzaldehida | |
| HRP20211011T1 (hr) | N-[4-fluor-5-[[(2s,4s)-2-metil-4-[(5-metil-1,2,4-oksadiazol-3-il)metoksi]-1-piperidil]metil]tiazol-2-il]acetamid kao inhibitor oga | |
| JP2011522816A5 (enExample) | ||
| JP2016041701A5 (enExample) | ||
| JP2015145426A5 (enExample) | ||
| JP2018035160A5 (enExample) | ||
| NZ712180A (en) | Pyridazinone compounds and methods for the treatment of cystic fibrosis | |
| SI2956452T1 (en) | Heterocyclic amides as kinase inhibitors | |
| RU2599785C3 (ru) | Кристаллические формы 5-хлор-n2-(2-изопропокси-5-метил-4-пиперидин-4-ил-фенил)-n4-[2-(пропан-2-сульфонил)-фенил]-пиримидин-2,4-диамина | |
| JP2016065042A5 (enExample) | ||
| JP2016503010A5 (enExample) | ||
| JP2014162794A5 (enExample) | ||
| JP2010132668A5 (enExample) | ||
| RU2019105794A (ru) | Кристаллогидрат соединения (2s, 3r) -изопропил 2 - (((2- (1,5-диметил-6-оксо-1,6-дигидропиридин-3-ил) -1 - ((тетрагидро-2h-пиран) -4-ил) метил) -1h-бензо [d] имидазол-5-ил) метил) амино) -3-гидроксибутаноат эдисилат | |
| JP2012516344A5 (enExample) | ||
| WO2013188283A8 (en) | Topical ophthalmological pharmaceutical composition containing sunitinib | |
| JP2016540749A5 (enExample) | ||
| JP2013503134A5 (enExample) |