JP2013544069A5 - - Google Patents
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- Publication number
- JP2013544069A5 JP2013544069A5 JP2013512280A JP2013512280A JP2013544069A5 JP 2013544069 A5 JP2013544069 A5 JP 2013544069A5 JP 2013512280 A JP2013512280 A JP 2013512280A JP 2013512280 A JP2013512280 A JP 2013512280A JP 2013544069 A5 JP2013544069 A5 JP 2013544069A5
- Authority
- JP
- Japan
- Prior art keywords
- cyclin
- family
- nuclear reprogramming
- proteins
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 108090000623 proteins and genes Proteins 0.000 claims 8
- 230000008672 reprogramming Effects 0.000 claims 7
- 210000001082 somatic cell Anatomy 0.000 claims 7
- 239000000126 substance Substances 0.000 claims 6
- 102000003910 Cyclin D Human genes 0.000 claims 5
- 108090000259 Cyclin D Proteins 0.000 claims 5
- 108010058546 Cyclin D1 Proteins 0.000 claims 4
- 108010058545 Cyclin D3 Proteins 0.000 claims 4
- 102100024165 G1/S-specific cyclin-D1 Human genes 0.000 claims 4
- 102100037859 G1/S-specific cyclin-D3 Human genes 0.000 claims 4
- 108700021430 Kruppel-Like Factor 4 Proteins 0.000 claims 4
- 108010058544 Cyclin D2 Proteins 0.000 claims 3
- 102100024185 G1/S-specific cyclin-D2 Human genes 0.000 claims 3
- 101100247004 Rattus norvegicus Qsox1 gene Proteins 0.000 claims 3
- 101150086694 SLC22A3 gene Proteins 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 230000004069 differentiation Effects 0.000 claims 2
- 238000011419 induction treatment Methods 0.000 claims 2
- 108091057508 Myc family Proteins 0.000 claims 1
- 101710135898 Myc proto-oncogene protein Proteins 0.000 claims 1
- 102100038895 Myc proto-oncogene protein Human genes 0.000 claims 1
- 101710150448 Transcriptional regulator Myc Proteins 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41017810P | 2010-11-04 | 2010-11-04 | |
| US61/410,178 | 2010-11-04 | ||
| PCT/JP2011/076017 WO2012060473A1 (en) | 2010-11-04 | 2011-11-04 | Method of efficiently establishing induced pluripotent stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544069A JP2013544069A (ja) | 2013-12-12 |
| JP2013544069A5 true JP2013544069A5 (cg-RX-API-DMAC7.html) | 2014-12-18 |
| JP5888753B2 JP5888753B2 (ja) | 2016-03-22 |
Family
ID=46024582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013512280A Active JP5888753B2 (ja) | 2010-11-04 | 2011-11-04 | 効率的な人工多能性幹細胞の樹立方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9637732B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2635678A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5888753B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012060473A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| KR20250035015A (ko) | 2011-12-05 | 2025-03-11 | 팩터 바이오사이언스 인크. | 세포를 형질감염시키는 방법들 및 생성물들 |
| BR122019025681B1 (pt) | 2012-11-01 | 2023-04-18 | Factor Bioscience Inc | Método para inserir uma sequência de ácido nucleico em uma localização segura de um genoma de uma célula |
| MX372651B (es) | 2014-01-31 | 2020-06-16 | Factor Bioscience Inc | ARN SINTÉTICO PARA SU Uso EN EL TRATAMIENTO DE LA EPIDERMÓLISIS AMPOLLOSA DISTRÓFICA. |
| JP7199809B2 (ja) | 2015-02-13 | 2023-01-06 | ファクター バイオサイエンス インコーポレイテッド | 核酸製品及びその投与方法 |
| JP7563872B2 (ja) | 2016-05-25 | 2024-10-08 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 癌を処置するための方法及び組成物 |
| EP3500585A4 (en) | 2016-08-17 | 2020-04-01 | Factor Bioscience Inc. | NUCLEIC ACID PRODUCTS AND METHODS OF ADMINISTRATION |
| US11679148B2 (en) | 2017-11-24 | 2023-06-20 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Methods and compositions for treating cancers |
| US20210236633A1 (en) | 2018-08-06 | 2021-08-05 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treating cancers |
| WO2020230138A1 (en) | 2019-05-14 | 2020-11-19 | Aleph Farms Ltd. | Pluripotent cell aggregates and use thereof |
| CN114450265B (zh) | 2019-07-03 | 2024-12-24 | 菲克特生物科学股份有限公司 | 阳离子脂质及其用途 |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| JP2023550181A (ja) | 2020-11-24 | 2023-11-30 | モナシュ ユニバーシティ | 方法及び細胞構造体 |
| KR20230113768A (ko) | 2020-11-24 | 2023-08-01 | 모나쉬 유니버시티 | 유도 줄기 세포 |
| WO2022207889A1 (en) | 2021-04-01 | 2022-10-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Liver organoid manufacturing methods, liver organoids obtained with the same, and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ307399A0 (en) * | 1999-09-24 | 1999-10-21 | Luminis Pty Limited | Cell cycle control |
| US9567591B2 (en) * | 2003-05-15 | 2017-02-14 | Mello Biotechnology, Inc. | Generation of human embryonic stem-like cells using intronic RNA |
| AU2006325975B2 (en) | 2005-12-13 | 2011-12-08 | Kyoto University | Nuclear reprogramming factor |
| CA2683056C (en) | 2007-04-07 | 2020-03-24 | Whitehead Institute For Biomedical Research | Reprogramming of somatic cells |
| CA2660123C (en) | 2007-10-31 | 2017-05-09 | Kyoto University | Nuclear reprogramming method |
| CN101970664B (zh) | 2008-01-16 | 2013-08-21 | 林希龙 | 使用可诱导的重组核糖核酸因子生成不含肿瘤的类胚胎干细胞的多能性细胞 |
| JP2011525794A (ja) * | 2008-06-26 | 2011-09-29 | 国立大学法人大阪大学 | ｉＰＳ細胞の製造方法および製造キット |
| CA2695590C (en) * | 2008-06-27 | 2018-01-09 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| EP2295538B1 (en) * | 2008-07-07 | 2015-10-21 | Takara Bio Inc. | Method for production of pluripotent stem cell |
-
2011
- 2011-11-04 JP JP2013512280A patent/JP5888753B2/ja active Active
- 2011-11-04 US US13/824,087 patent/US9637732B2/en active Active
- 2011-11-04 EP EP11838120.1A patent/EP2635678A4/en not_active Withdrawn
- 2011-11-04 WO PCT/JP2011/076017 patent/WO2012060473A1/en not_active Ceased
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