JP2013542955A5 - - Google Patents

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Publication number
JP2013542955A5
JP2013542955A5 JP2013537733A JP2013537733A JP2013542955A5 JP 2013542955 A5 JP2013542955 A5 JP 2013542955A5 JP 2013537733 A JP2013537733 A JP 2013537733A JP 2013537733 A JP2013537733 A JP 2013537733A JP 2013542955 A5 JP2013542955 A5 JP 2013542955A5
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JP
Japan
Prior art keywords
agent
compound
hcv
compound according
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013537733A
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English (en)
Japanese (ja)
Other versions
JP5828903B2 (ja
JP2013542955A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/058404 external-priority patent/WO2012061248A2/en
Publication of JP2013542955A publication Critical patent/JP2013542955A/ja
Publication of JP2013542955A5 publication Critical patent/JP2013542955A5/ja
Application granted granted Critical
Publication of JP5828903B2 publication Critical patent/JP5828903B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013537733A 2010-11-01 2011-10-28 新規特異的hcv ns3プロテアーゼ阻害剤 Expired - Fee Related JP5828903B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40898910P 2010-11-01 2010-11-01
US61/408,989 2010-11-01
PCT/US2011/058404 WO2012061248A2 (en) 2010-11-01 2011-10-28 Novel specific hcv ns3 protease inhibitors

Publications (3)

Publication Number Publication Date
JP2013542955A JP2013542955A (ja) 2013-11-28
JP2013542955A5 true JP2013542955A5 (https=) 2015-02-12
JP5828903B2 JP5828903B2 (ja) 2015-12-09

Family

ID=46025037

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013537733A Expired - Fee Related JP5828903B2 (ja) 2010-11-01 2011-10-28 新規特異的hcv ns3プロテアーゼ阻害剤

Country Status (10)

Country Link
US (1) US8729014B2 (https=)
EP (1) EP2635570B1 (https=)
JP (1) JP5828903B2 (https=)
CN (1) CN103328466B (https=)
AU (1) AU2011323658A1 (https=)
BR (1) BR112013010836A2 (https=)
CA (1) CA2815855C (https=)
IL (1) IL225908A0 (https=)
MX (1) MX2013004906A (https=)
WO (1) WO2012061248A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011268498A1 (en) 2010-06-24 2013-01-31 Genoscience Pharma Sas Treatment of hepatitis C virus related diseases using hydroxychloroquine or a combination of hydroxychloroquine and an anti-viral agent
WO2012061248A2 (en) 2010-11-01 2012-05-10 Rfs Pharma, Llc Novel specific hcv ns3 protease inhibitors
US8912141B2 (en) 2011-06-23 2014-12-16 Panmed Ltd. Treatment of hepatitis C virus
US9040479B2 (en) 2012-01-12 2015-05-26 Cocrystal Pharma, Inc. HCV NS3 protease inhibitors
UA119315C2 (uk) 2012-07-03 2019-06-10 Гіліад Фармассет Елелсі Інгібітори вірусу гепатиту с
US9617310B2 (en) 2013-03-15 2017-04-11 Gilead Sciences, Inc. Inhibitors of hepatitis C virus
JP2017513852A (ja) * 2014-04-15 2017-06-01 コクリスタル ファーマ,インコーポレイテッド C型肝炎ウイルスの強力及び選択的な阻害剤
CN105315261A (zh) * 2014-08-04 2016-02-10 正大天晴药业集团股份有限公司 Hcv ns3蛋白酶抑制剂的钠盐

Family Cites Families (26)

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Publication number Priority date Publication date Assignee Title
WO1995000536A1 (en) 1993-06-22 1995-01-05 Fujisawa Pharmaceutical Co., Ltd. Peptide compounds
AP1019A (en) 1996-10-18 2001-10-16 Vertex Pharma Inhibitors of serinre proteases, particularly hepatitis C virus NS3 protease.
US6767991B1 (en) 1997-08-11 2004-07-27 Boehringer Ingelheim (Canada) Ltd. Hepatitis C inhibitor peptides
AU2001251165A1 (en) 2000-04-03 2001-10-15 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
CA2462200A1 (en) 2001-08-10 2003-02-20 Palatin Technologies, Inc. Peptidomimetics of biologically active metallopeptides
MY140680A (en) 2002-05-20 2010-01-15 Bristol Myers Squibb Co Hepatitis c virus inhibitors
ES2361011T3 (es) 2002-05-20 2011-06-13 Bristol-Myers Squibb Company Inhibidores del virus de la hepatitis c.
CA2531068A1 (en) 2003-07-10 2005-01-27 Achillion Pharmaceuticals, Inc. Substituted arylthiourea derivatives useful as inhibitors of viral replication
PL1713822T3 (pl) 2004-01-30 2010-08-31 Medivir Ab Inhibitory proteazy serynowej HCV NS-3
DE602005015452D1 (de) 2004-05-20 2009-08-27 Schering Corp Substituierte proline als hemmer der ns3-serinprotease des hepatits-c-virus
US7323447B2 (en) * 2005-02-08 2008-01-29 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US20080191609A1 (en) 2005-04-19 2008-08-14 Koninklijke Philips Electronics N.V. Illumination System Comprising a Red-Emitting Ceramic Luminescence Converter
AR057456A1 (es) 2005-07-20 2007-12-05 Merck & Co Inc Inhibidores de la proteasa ns3 del vhc
NZ565269A (en) 2005-08-01 2010-03-26 Merck & Co Inc Macrocyclic peptides as HCV NS3 protease inhibitors
US20090304631A1 (en) 2006-01-27 2009-12-10 David Alan Campbell Hepatitis c serine protease inhibitors and uses therefor
CN101495457A (zh) * 2006-07-05 2009-07-29 因特蒙公司 C型肝炎病毒复制的新颖抑制剂
RU2008152171A (ru) 2006-07-05 2010-08-10 Интермьюн, Инк. (Us) Новые ингибиторы вирусной репликации гепатита с
US7635683B2 (en) 2006-08-04 2009-12-22 Enanta Pharmaceuticals, Inc. Quinoxalinyl tripeptide hepatitis C virus inhibitors
JP5035251B2 (ja) 2006-11-24 2012-09-26 株式会社島津製作所 X線透視撮影装置
US20080287449A1 (en) 2007-04-26 2008-11-20 Deqiang Niu Aza-tripeptide hepatitis c serine protease inhibitors
MX2010006210A (es) 2007-12-05 2010-08-10 Enanta Pharm Inc Inhibidores de serina proteasa de hcv de tripeptido fluorado.
US8293705B2 (en) 2007-12-21 2012-10-23 Avila Therapeutics, Inc. HCV protease inhibitors and uses thereof
TWI487522B (zh) * 2007-12-21 2015-06-11 賽基艾維洛米斯研究股份有限公司 Hcv蛋白酶抑制劑及其用途(一)
WO2009142842A2 (en) 2008-04-15 2009-11-26 Intermune, Inc. Novel macrocyclic inhibitors of hepatitis c virus replication
KR101781789B1 (ko) 2010-01-27 2017-09-26 에이비 파르마 리미티드. C형 간염 바이러스 억제제로 사용되는 다환 헤테로사이클릭 화합물
WO2012061248A2 (en) 2010-11-01 2012-05-10 Rfs Pharma, Llc Novel specific hcv ns3 protease inhibitors

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