JP2013542228A - Ｅｇｆｒ依存性疾患またはｅｇｆｒファミリーメンバーを標的とする薬剤に対して獲得耐性を有する疾患の治療における２−カルボキサミドシクロアミノウレア誘導体の使用 - Google Patents
Ｅｇｆｒ依存性疾患またはｅｇｆｒファミリーメンバーを標的とする薬剤に対して獲得耐性を有する疾患の治療における２−カルボキサミドシクロアミノウレア誘導体の使用 Download PDFInfo
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| PCT/EP2011/069522 WO2012062694A1 (en) | 2010-11-08 | 2011-11-07 | Use of 2-carboxamide cycloamino urea derivatives in the treatment of egfr dependent diseases or diseases that have acquired resistance to agents that target egfr family members |
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| JP2016134705A Withdrawn JP2016222686A (ja) | 2010-11-08 | 2016-07-07 | Ｅｇｆｒ依存性疾患またはｅｇｆｒファミリーメンバーを標的とする薬剤に対して獲得耐性を有する疾患の治療における２−カルボキサミドシクロアミノウレア誘導体の使用 |
| JP2018199647A Withdrawn JP2019048822A (ja) | 2010-11-08 | 2018-10-24 | Ｅｇｆｒ依存性疾患またはｅｇｆｒファミリーメンバーを標的とする薬剤に対して獲得耐性を有する疾患の治療における２−カルボキサミドシクロアミノウレア誘導体の使用 |
| JP2020056250A Pending JP2020114849A (ja) | 2010-11-08 | 2020-03-26 | Ｅｇｆｒ依存性疾患またはｅｇｆｒファミリーメンバーを標的とする薬剤に対して獲得耐性を有する疾患の治療における２−カルボキサミドシクロアミノウレア誘導体の使用 |
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| JP2018199647A Withdrawn JP2019048822A (ja) | 2010-11-08 | 2018-10-24 | Ｅｇｆｒ依存性疾患またはｅｇｆｒファミリーメンバーを標的とする薬剤に対して獲得耐性を有する疾患の治療における２−カルボキサミドシクロアミノウレア誘導体の使用 |
| JP2020056250A Pending JP2020114849A (ja) | 2010-11-08 | 2020-03-26 | Ｅｇｆｒ依存性疾患またはｅｇｆｒファミリーメンバーを標的とする薬剤に対して獲得耐性を有する疾患の治療における２−カルボキサミドシクロアミノウレア誘導体の使用 |
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| JP2016539149A (ja) * | 2013-12-06 | 2016-12-15 | ノバルティス アーゲー | アルファ−アイソフォーム選択的ホスファチジルイノシトール３−キナーゼ阻害剤の投薬レジメン |
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| AU2012322976B2 (en) * | 2011-10-14 | 2016-05-12 | Novartis Ag | 2 - carboxamide cycloamino urea derivatives in combination with Hsp90 inhibitors for the treatment of proliferative diseases |
| KR20140088869A (ko) * | 2011-11-02 | 2014-07-11 | 노파르티스 아게 | Vegf-의존성 질환의 치료에 사용하기 위한 2-카르복스아미드 시클로아미노 우레아 유도체 |
| HK1211831A1 (zh) * | 2012-08-07 | 2016-06-03 | Novartis Ag | 包含B-RAF抑制剂、EGFR抑制剂和任选PI3Kα抑制剂的药物组合 |
| HK1211476A1 (en) * | 2012-08-16 | 2016-05-27 | Novartis Ag | Combination of pi3k inhibitor and c-met inhibitor |
| US20160030440A1 (en) * | 2013-04-05 | 2016-02-04 | Sanofi | Anti-tumoral composition comprising a pi3kbeta-selective inhibitor and a pi3kalpha-selective inhibitor |
| IL280880B2 (en) | 2018-08-27 | 2025-04-01 | Regeneron Pharma | Using Raman Spectroscopy in Downstream Purification |
| CA3112043A1 (en) | 2018-09-10 | 2020-03-19 | Mirati Therapeutics, Inc. | Combination therapies |
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| JP2006525266A (ja) * | 2003-05-02 | 2006-11-09 | ノバルティス アクチエンゲゼルシャフト | ホスファチジルイノシトール３−キナーゼの阻害剤 |
| WO2009080694A1 (en) * | 2007-12-20 | 2009-07-02 | Novartis Ag | Thiazole derivatives used as pi 3 kinase inhibitors |
| WO2010029082A1 (en) * | 2008-09-10 | 2010-03-18 | Novartis Ag | Organic compounds |
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| MY130778A (en) * | 2001-02-09 | 2007-07-31 | Vertex Pharma | Heterocyclic inhibitiors of erk2 and uses thereof |
| HUE025507T2 (en) * | 2008-03-18 | 2016-02-29 | Genentech Inc | Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use |
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2015
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2016
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2018
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006525266A (ja) * | 2003-05-02 | 2006-11-09 | ノバルティス アクチエンゲゼルシャフト | ホスファチジルイノシトール３−キナーゼの阻害剤 |
| WO2009080694A1 (en) * | 2007-12-20 | 2009-07-02 | Novartis Ag | Thiazole derivatives used as pi 3 kinase inhibitors |
| WO2010029082A1 (en) * | 2008-09-10 | 2010-03-18 | Novartis Ag | Organic compounds |
Non-Patent Citations (2)
| Title |
|---|
| JPN5014001058; ＣＡＲＭＥＬ Ｔ． ＣＨＡＮ: 'ＤＩＦＦＥＲＥＮＴＩＡＬ ＳＥＮＳＩＴＩＶＩＴＩＥＳ ＯＦ ＴＲＡＳＴＵＺＵＭＡＢ （ＨＥＲＣＥＰＴＩＮ（Ｒ））-ＲＥＳＩＳＴＡＮＴ ＨＵＭＡＮ ＢＲＥＡＳＴ ＣＡＮＣＥＲ 以下備考' ＢＲＥＡＳＴ ＣＡＮＣＥＲ ＲＥＳＥＡＲＣＨ ＡＮＤ ＴＲＥＡＴＭＥＮＴ Ｖ９１ Ｎ２, 20050501, Ｐ１８７-２０１, ＫＬＵＷＥＲ ＡＣＡＤＥＭＩＣ ＰＵＢＬＩＳＨＥＲＳ * |
| JPN6015035499; Ｃａｎｃｅｒ Ｃｅｌｌ， ２００５， Ｖｏｌ．８， ｐ．２８７-２９７ * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016539149A (ja) * | 2013-12-06 | 2016-12-15 | ノバルティス アーゲー | アルファ−アイソフォーム選択的ホスファチジルイノシトール３−キナーゼ阻害剤の投薬レジメン |
Also Published As
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|---|---|
| CN105412105A (zh) | 2016-03-23 |
| KR101854484B1 (ko) | 2018-05-03 |
| EP2637661A1 (en) | 2013-09-18 |
| CA2815492C (en) | 2019-04-09 |
| US20130209461A1 (en) | 2013-08-15 |
| AU2011328227B2 (en) | 2015-04-09 |
| AU2011328227A1 (en) | 2013-04-18 |
| US20200022967A1 (en) | 2020-01-23 |
| MX2013005182A (es) | 2013-07-03 |
| US20180325883A1 (en) | 2018-11-15 |
| JP2019048822A (ja) | 2019-03-28 |
| MX360157B (es) | 2018-10-24 |
| US20150250778A1 (en) | 2015-09-10 |
| TR201802943T4 (tr) | 2018-03-21 |
| BR112013009624A2 (pt) | 2016-07-12 |
| RU2013126485A (ru) | 2014-12-20 |
| JP2016222686A (ja) | 2016-12-28 |
| EP2637661B1 (en) | 2017-12-20 |
| JP2020114849A (ja) | 2020-07-30 |
| CA2815492A1 (en) | 2012-05-18 |
| RU2589695C2 (ru) | 2016-07-10 |
| KR20130143582A (ko) | 2013-12-31 |
| CN103200943A (zh) | 2013-07-10 |
| WO2012062694A1 (en) | 2012-05-18 |
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