JP2013535963A5 - - Google Patents

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Publication number
JP2013535963A5
JP2013535963A5 JP2013519215A JP2013519215A JP2013535963A5 JP 2013535963 A5 JP2013535963 A5 JP 2013535963A5 JP 2013519215 A JP2013519215 A JP 2013519215A JP 2013519215 A JP2013519215 A JP 2013519215A JP 2013535963 A5 JP2013535963 A5 JP 2013535963A5
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JP
Japan
Prior art keywords
seq
diabetes
isolated
complex
high affinity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013519215A
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English (en)
Japanese (ja)
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JP2013535963A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/IL2011/000563 external-priority patent/WO2012007950A2/en
Publication of JP2013535963A publication Critical patent/JP2013535963A/ja
Publication of JP2013535963A5 publication Critical patent/JP2013535963A5/ja
Pending legal-status Critical Current

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JP2013519215A 2010-07-15 2011-07-14 Mhcクラスiiと糖尿病関連自己抗原性ペプチドとの天然型複合体に対するt細胞受容体様特異性を有する単離された高親和性実体 Pending JP2013535963A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36443710P 2010-07-15 2010-07-15
US61/364,437 2010-07-15
PCT/IL2011/000563 WO2012007950A2 (en) 2010-07-15 2011-07-14 Isolated high affinity entities with t-cell receptor like specificity towards native complexes of mhc class ii and diabetes-associated autoantigenic peptides

Publications (2)

Publication Number Publication Date
JP2013535963A JP2013535963A (ja) 2013-09-19
JP2013535963A5 true JP2013535963A5 (https=) 2014-08-28

Family

ID=44504047

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013519215A Pending JP2013535963A (ja) 2010-07-15 2011-07-14 Mhcクラスiiと糖尿病関連自己抗原性ペプチドとの天然型複合体に対するt細胞受容体様特異性を有する単離された高親和性実体

Country Status (5)

Country Link
US (1) US20130189284A1 (https=)
EP (1) EP2593480A2 (https=)
JP (1) JP2013535963A (https=)
CA (1) CA2805478A1 (https=)
WO (1) WO2012007950A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012007951A1 (en) 2010-07-15 2012-01-19 Technion Research & Development Foundation Ltd. Isolated high affinity entities with t-cell receptor like specificity towards native complexes of mhc class ii and glutamic acid decarboxylase (gad) autoantigenic peptides
AU2015321365B2 (en) * 2014-09-26 2021-05-20 The University Of British Columbia A combination of kynurenine and antigen presenting cells (APC) as therapeutics and methods for their use in immune modulation
EP3221344A2 (en) * 2014-11-21 2017-09-27 Immusant Inc. Peptides for use in treatment and diagnosis of type 1 diabetes
GB201506112D0 (en) * 2015-04-10 2015-05-27 Midatech Ltd And Inst Nationale De La Sant� Et De Al Rech Medicale And University College Car Nanoparticle-based antigen specific immunotherapy
WO2016174652A1 (en) 2015-04-30 2016-11-03 Technion Research & Development Foundation Limited Chimeric antigen receptors and methods of their use
JP7057748B2 (ja) 2015-07-16 2022-04-20 イェダ リサーチ アンド ディベロップメント カンパニー リミテッド 遺伝子改変された抗第三者中枢性メモリーt細胞および免疫療法におけるその使用
GB201520568D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd Peptides
GB201520603D0 (en) * 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
GB201520550D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
CN110392736A (zh) 2017-01-18 2019-10-29 耶达研究及发展有限公司 遗传修饰的反抑细胞及其在免疫治疗中的用途
US12153056B2 (en) 2019-07-15 2024-11-26 Washington University Compositions for and methods of diagnosing, prognosing, and treating diabetes
EP4384603A1 (en) 2021-08-10 2024-06-19 Gamida-Cell Ltd. Engineered nk cells, methods of their production and uses thereof
GB202210967D0 (en) * 2022-07-27 2022-09-07 Univ Birmingham Tolerogenic peptides i
US20260041747A1 (en) * 2022-07-29 2026-02-12 Repertoire Immune Medicines, Inc. T cell epitopes associated with type 1 diabetes

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