JP2013531034A5 - - Google Patents
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- JP2013531034A5 JP2013531034A5 JP2013519600A JP2013519600A JP2013531034A5 JP 2013531034 A5 JP2013531034 A5 JP 2013531034A5 JP 2013519600 A JP2013519600 A JP 2013519600A JP 2013519600 A JP2013519600 A JP 2013519600A JP 2013531034 A5 JP2013531034 A5 JP 2013531034A5
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- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Description
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2010-0067796 | 2010-07-14 | ||
KR1020100067796A KR101337797B1 (ko) | 2010-07-14 | 2010-07-14 | 지속형 인간 성장 호르몬 결합체 액상 제제 |
PCT/KR2011/005194 WO2012008779A2 (en) | 2010-07-14 | 2011-07-14 | A liquid formulation of long-acting human growth hormone conjugate |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2013531034A JP2013531034A (ja) | 2013-08-01 |
JP2013531034A5 true JP2013531034A5 (ja) | 2015-10-15 |
JP5946448B2 JP5946448B2 (ja) | 2016-07-06 |
Family
ID=45469941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013519600A Expired - Fee Related JP5946448B2 (ja) | 2010-07-14 | 2011-07-14 | 持続型ヒト成長ホルモン結合体液状製剤 |
Country Status (13)
Country | Link |
---|---|
US (1) | US9061072B2 (ja) |
EP (1) | EP2593084B1 (ja) |
JP (1) | JP5946448B2 (ja) |
KR (1) | KR101337797B1 (ja) |
AR (2) | AR082223A1 (ja) |
AU (1) | AU2011277203B2 (ja) |
BR (1) | BR112013000902A2 (ja) |
CA (1) | CA2805228C (ja) |
ES (1) | ES2673022T3 (ja) |
IL (1) | IL224225B (ja) |
RU (1) | RU2623026C2 (ja) |
TW (1) | TWI459961B (ja) |
WO (1) | WO2012008779A2 (ja) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20181268A1 (es) | 2011-06-17 | 2018-08-03 | Hanmi Science Co Ltd | Un conjugado que comprende oxintomodulina y un fragmento de inmunoglobulina, y el uso del mismo |
KR20130049671A (ko) | 2011-11-04 | 2013-05-14 | 한미사이언스 주식회사 | 생리활성 폴리펩타이드 결합체 제조 방법 |
AR090281A1 (es) | 2012-03-08 | 2014-10-29 | Hanmi Science Co Ltd | Proceso mejorado para la preparacion de un complejo polipeptidico fisiologicamente activo |
US10064951B2 (en) * | 2012-03-30 | 2018-09-04 | Hanmi Science Co., Ltd. | Liquid formulation of highly concentrated long-acting human growth hormone conjugate |
AR092862A1 (es) * | 2012-07-25 | 2015-05-06 | Hanmi Pharm Ind Co Ltd | Formulacion liquida de insulina de accion prolongada y un peptido insulinotropico y metodo de preparacion |
AR091902A1 (es) | 2012-07-25 | 2015-03-11 | Hanmi Pharm Ind Co Ltd | Formulacion liquida de un conjugado de insulina de accion prolongada |
AR093387A1 (es) * | 2012-11-06 | 2015-06-03 | Hanmi Pharm Ind Co Ltd | Formulacion liquida de un conjugado de proteina que comprende oxintomodulina y un fragmento de inmunoglobulina |
US20160017017A1 (en) | 2013-03-11 | 2016-01-21 | Novo Nordisk Healthcare Ag | Growth Hormone Compounds |
CN105229035A (zh) * | 2013-03-11 | 2016-01-06 | 诺和诺德保健股份有限公司 | 生长激素化合物 |
WO2015046974A1 (ko) * | 2013-09-27 | 2015-04-02 | 한미약품 주식회사 | 지속형 인간 성장 호르몬 제제 |
MY192248A (en) * | 2014-03-31 | 2022-08-10 | Hanmi Pharm Ind Co Ltd | Method for improving solubility of protein and peptide by using immunoglobulin fc fragment linkage |
TWI802396B (zh) | 2014-09-16 | 2023-05-11 | 南韓商韓美藥品股份有限公司 | 長效glp-1/高血糖素受體雙促效劑治療非酒精性脂肝疾病之用途 |
WO2016092550A2 (en) * | 2014-12-10 | 2016-06-16 | Opko Biologics Ltd. | Methods of producing long acting ctp-modified polypeptides |
KR102418477B1 (ko) | 2014-12-30 | 2022-07-08 | 한미약품 주식회사 | 글루카곤 유도체 |
US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9375478B1 (en) * | 2015-01-30 | 2016-06-28 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US11208452B2 (en) | 2015-06-02 | 2021-12-28 | Novo Nordisk A/S | Insulins with polar recombinant extensions |
DK3347031T3 (da) * | 2015-09-11 | 2021-04-26 | Nutrition & Biosciences Usa 1 Llc | Sammensætning, der omfatter et protein og en polyalkoxyfedtforbindelse |
US10301428B2 (en) | 2015-09-11 | 2019-05-28 | Dow Global Technologies Llc | Polyalkoxy fatty compound |
TWI756185B (zh) * | 2015-09-24 | 2022-03-01 | 美商拜奧馬林製藥公司 | 腺相關病毒因子viii載體、相關病毒粒子及包含其之治療調配物 |
MA43348A (fr) | 2015-10-01 | 2018-08-08 | Novo Nordisk As | Conjugués de protéines |
KR20170079409A (ko) * | 2015-12-30 | 2017-07-10 | 한미약품 주식회사 | 지속형 인간 성장 호르몬 결합체의 신규 액상 제제 |
WO2018185131A2 (en) | 2017-04-05 | 2018-10-11 | Novo Nordisk A/S | Oligomer extended insulin-fc conjugates |
KR20220095204A (ko) * | 2019-10-30 | 2022-07-06 | 제이씨알 파마 가부시키가이샤 | 혈청 알부민과 성장 호르몬의 융합 단백질을 함유하는 수성 의약 조성물 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5981485A (en) * | 1997-07-14 | 1999-11-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
US5096885A (en) * | 1988-04-15 | 1992-03-17 | Genentech, Inc. | Human growth hormone formulation |
SE9201073D0 (sv) | 1992-04-03 | 1992-04-03 | Kabi Pharmacia Ab | Protein formulation |
ATE359824T1 (de) * | 1992-07-31 | 2007-05-15 | Genentech Inc | Wässrige formulierung enthaltend menschliches wachstumshormon |
US5519253A (en) * | 1993-09-07 | 1996-05-21 | Delco Electronics Corp. | Coaxial switch module |
US20020077461A1 (en) * | 1996-04-24 | 2002-06-20 | Soren Bjorn | Pharmaceutical formulation |
JP3723857B2 (ja) * | 1998-02-04 | 2005-12-07 | 日本ケミカルリサーチ株式会社 | ヒト成長ホルモン含有水性医薬組成物 |
EP1200124B1 (en) * | 1999-07-13 | 2008-09-10 | Bolder Biotechnology, Inc. | Erythropoietin-immunoglobulin fusion proteins |
GB2371227A (en) * | 2001-01-10 | 2002-07-24 | Grandis Biotech Gmbh | Crystallisation - resistant aqueous growth hormone formulations |
US20060183197A1 (en) * | 2001-01-11 | 2006-08-17 | Andersen Kim V | Variant growth hormone molecules conjugated with macromolecules compounds |
US20050176108A1 (en) * | 2003-03-13 | 2005-08-11 | Young-Min Kim | Physiologically active polypeptide conjugate having prolonged in vivo half-life |
US20040180054A1 (en) | 2003-03-13 | 2004-09-16 | Hanmi Pharm. Co., Ltd. | Physiologically active polypeptide conjugate having prolonged in vivo half-life |
KR100537260B1 (ko) * | 2003-09-03 | 2005-12-19 | 한미약품 주식회사 | 인간 성장 호르몬의 안정화된 액상 제제용 조성물 |
ATE522548T1 (de) * | 2003-11-13 | 2011-09-15 | Hanmi Holdings Co Ltd | Verfahren zur massenproduktion der konstanten region von immunglobulin |
WO2005063298A1 (en) * | 2003-12-23 | 2005-07-14 | Pharmacia Corporation | Stable growth hormone liquid formulation |
US8077437B2 (en) * | 2004-11-08 | 2011-12-13 | Enecsys Limited | Integrated circuits and power supplies |
KR100754667B1 (ko) | 2005-04-08 | 2007-09-03 | 한미약품 주식회사 | 비펩타이드성 중합체로 개질된 면역글로불린 Fc 단편 및이를 포함하는 약제학적 조성물 |
KR100739728B1 (ko) * | 2005-09-01 | 2007-07-13 | 삼성전자주식회사 | 화상형성시스템 및 화상 형성 방법 |
US8400775B2 (en) * | 2007-07-06 | 2013-03-19 | GM Global Technology Operations LLC | Capacitor with direct DC connection to substrate |
CA2731546C (en) * | 2008-07-23 | 2013-11-19 | Hanmi Holdings Co., Ltd. | A polypeptide complex comprising non-peptidyl polymer having three functional ends |
NZ606283A (en) * | 2008-11-28 | 2014-08-29 | Abbvie Inc | Stable antibody compositions and methods for stabilizing same |
-
2010
- 2010-07-14 KR KR1020100067796A patent/KR101337797B1/ko active IP Right Grant
-
2011
- 2011-07-14 TW TW100125060A patent/TWI459961B/zh not_active IP Right Cessation
- 2011-07-14 AU AU2011277203A patent/AU2011277203B2/en not_active Ceased
- 2011-07-14 JP JP2013519600A patent/JP5946448B2/ja not_active Expired - Fee Related
- 2011-07-14 AR ARP110102545A patent/AR082223A1/es not_active Application Discontinuation
- 2011-07-14 BR BR112013000902-0A patent/BR112013000902A2/pt not_active IP Right Cessation
- 2011-07-14 RU RU2013106276A patent/RU2623026C2/ru not_active IP Right Cessation
- 2011-07-14 US US13/809,783 patent/US9061072B2/en not_active Expired - Fee Related
- 2011-07-14 WO PCT/KR2011/005194 patent/WO2012008779A2/en active Application Filing
- 2011-07-14 CA CA2805228A patent/CA2805228C/en not_active Expired - Fee Related
- 2011-07-14 ES ES11807064.8T patent/ES2673022T3/es active Active
- 2011-07-14 EP EP11807064.8A patent/EP2593084B1/en not_active Not-in-force
-
2013
- 2013-01-14 IL IL224225A patent/IL224225B/en active IP Right Grant
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2018
- 2018-03-20 AR ARP180100643A patent/AR113034A2/es unknown