DK3347031T3 - Sammensætning, der omfatter et protein og en polyalkoxyfedtforbindelse - Google Patents

Sammensætning, der omfatter et protein og en polyalkoxyfedtforbindelse Download PDF

Info

Publication number
DK3347031T3
DK3347031T3 DK16766167.7T DK16766167T DK3347031T3 DK 3347031 T3 DK3347031 T3 DK 3347031T3 DK 16766167 T DK16766167 T DK 16766167T DK 3347031 T3 DK3347031 T3 DK 3347031T3
Authority
DK
Denmark
Prior art keywords
polyalcoxy
protein
composition including
fat compound
fat
Prior art date
Application number
DK16766167.7T
Other languages
English (en)
Inventor
Joshua S Katz
David J Brennan
Florin Dan
Yujing Tan
Susan L Jordan
Timothy J Young
Yang Song
Original Assignee
Nutrition & Biosciences Usa 1 Llc
Rohm & Haas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutrition & Biosciences Usa 1 Llc, Rohm & Haas filed Critical Nutrition & Biosciences Usa 1 Llc
Application granted granted Critical
Publication of DK3347031T3 publication Critical patent/DK3347031T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G71/00—Macromolecular compounds obtained by reactions forming a ureide or urethane link, otherwise, than from isocyanate radicals in the main chain of the macromolecule
    • C08G71/02—Polyureas
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/10—Esters; Ether-esters
    • C08K5/101—Esters; Ether-esters of monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
    • C08G2650/50—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type containing nitrogen, e.g. polyetheramines or Jeffamines(r)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
    • C08G2650/58—Ethylene oxide or propylene oxide copolymers, e.g. pluronics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DK16766167.7T 2015-09-11 2016-09-01 Sammensætning, der omfatter et protein og en polyalkoxyfedtforbindelse DK3347031T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562217136P 2015-09-11 2015-09-11
PCT/US2016/049850 WO2017044367A1 (en) 2015-09-11 2016-09-01 A composition comprising a protein and a polyalkoxy fatty compound

Publications (1)

Publication Number Publication Date
DK3347031T3 true DK3347031T3 (da) 2021-04-26

Family

ID=56926312

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16766167.7T DK3347031T3 (da) 2015-09-11 2016-09-01 Sammensætning, der omfatter et protein og en polyalkoxyfedtforbindelse

Country Status (8)

Country Link
US (2) US10647782B2 (da)
EP (1) EP3347031B8 (da)
JP (1) JP6883569B2 (da)
KR (1) KR20180051543A (da)
CN (1) CN108025033B (da)
BR (1) BR112018004717A2 (da)
DK (1) DK3347031T3 (da)
WO (1) WO2017044367A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3700922T3 (pl) * 2017-10-25 2022-03-21 Aquaporin A/S Pęcherzyk zawierający białko transbłonowe
CN113166393A (zh) * 2018-09-05 2021-07-23 广州龙沙制药有限公司 用于制备聚氧乙烯1,4-脱水山梨醇脂肪酸酯的方法
CN112672734B (zh) * 2018-09-10 2023-04-11 陶氏环球技术有限责任公司 包含蛋白质和聚烷氧基脂肪酰基表面活性剂的组合物
US20210322554A1 (en) * 2018-09-10 2021-10-21 Dow Global Technologies Llc A composition comprising a protein and a polyalkoxy fatty acyl surfactant
JP2023506173A (ja) * 2019-12-12 2023-02-15 ニュートリション アンド バイオサイエンシス ユーエスエー １，エルエルシー タンパク質のバイオプロセス
WO2022015779A1 (en) * 2020-07-15 2022-01-20 Nutrition & Biosciences Usa 1, Llc Bioprocess with reduced fouling on surfaces

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2183853A (en) 1934-12-22 1939-12-19 Ig Farbenindustrie Ag Polyoxyalkylene ether acid compounds containing a higher aliphatic group
JPS5412908B2 (da) 1973-09-11 1979-05-26
US4165405A (en) 1977-05-16 1979-08-21 Basf Wyandotte Corporation Fiber lubricants based upon fatty esters of heteric polyoxyalkylated alcohols
JPS6161625A (ja) * 1984-09-03 1986-03-29 Nippon Oil & Fats Co Ltd 無機粉末用油中分散剤
DE4336247A1 (de) * 1993-10-22 1995-04-27 Basf Ag Verwendung von endgruppenverschlossenen Fettsäureamidalkoxylaten
DE19509981C2 (de) 1995-03-18 1998-07-16 Kao Corp Tönungsshampoo
GB9606216D0 (en) 1996-03-25 1996-05-29 Scotia Holdings Plc Polyethylene glycol esters of fatty acids
TW553747B (en) 1997-10-30 2003-09-21 Ajinomoto Kk Nonionic surfactant
US6146622A (en) 1998-10-27 2000-11-14 Alcon Laboratories, Inc. Use of certain anionic amino acid based surfactants to enhance antimicrobial effectiveness of topically administrable pharmaceutical compositions
CN1409637A (zh) * 1999-10-14 2003-04-09 日清制油株式会社 皮肤美化剂、皮肤用抗老化剂、皮肤用增白剂和外用制剂
CA2404150A1 (en) * 2000-03-29 2001-10-04 Jeffrey Jon Vipond Low pour point primary amides
JP4880816B2 (ja) * 2000-12-15 2012-02-22 株式会社ヤクルト本社 皮膚老化防止剤
KR100858575B1 (ko) * 2000-12-19 2008-09-17 가부시키가이샤 야쿠루트 혼샤 피부 외용제 및 그 제조 방법
TWI238068B (en) * 2001-03-06 2005-08-21 Kao Corp Composition for external application
SI1475101T1 (sl) * 2002-02-14 2011-03-31 Chugai Pharmaceutical Co Ltd Farmacevtski proizvodi iz raztopine, ki vsebuje protitelo
WO2006038721A1 (ja) * 2004-10-07 2006-04-13 Toyo Shinyaku Co., Ltd. 外用剤
DE102005011608A1 (de) 2005-03-14 2006-09-21 Basf Ag Veresterte Alkylalkoxylate als schaumarme Tenside
GB0610140D0 (en) 2006-05-22 2006-06-28 Insense Ltd Protein stability
EP1899462B1 (en) 2005-07-02 2011-03-09 Arecor Limited Stable aqueous systems comprising proteins
ES2436616T5 (es) * 2005-12-20 2022-05-27 Bristol Myers Squibb Co Formulaciones proteicas estables
US9309316B2 (en) * 2005-12-20 2016-04-12 Bristol-Myers Squibb Company Stable subcutaneous protein formulations and uses thereof
US7998927B2 (en) 2006-06-23 2011-08-16 Aegis Therapeutics, Llc Stabilizing alkylglycoside compositions and methods thereof
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
EP2082022A4 (en) * 2006-11-13 2011-12-07 Croda Uniqema Inc COMPOUNDS
GB0700523D0 (en) 2007-01-11 2007-02-21 Insense Ltd The Stabilisation Of Proteins
JP2008255020A (ja) * 2007-04-02 2008-10-23 Fujifilm Corp 抗老化皮膚外用剤
WO2009065126A2 (en) 2007-11-16 2009-05-22 Boston Protein Solutions Excipients for protein stabilization
EP2301645A1 (en) 2009-09-28 2011-03-30 Cytec Surface Specialties Austria GmbH Defoamers for airless paint spray application
KR101337797B1 (ko) * 2010-07-14 2013-12-06 한미사이언스 주식회사 지속형 인간 성장 호르몬 결합체 액상 제제
CN101935521B (zh) * 2010-07-19 2013-01-02 江南大学 一种无碱驱油用醇酰胺类非离子型表面活性剂的应用
MY163076A (en) 2010-09-02 2017-08-15 Kolb Distrib Ltd Alkoxylation method of fatty acid alkyl esters
CN102058489B (zh) 2010-11-22 2014-09-24 苏州元素集化学工业有限公司 一种稠厚的清洁组合物
US20130029899A1 (en) 2011-07-28 2013-01-31 Conopco, Inc., D/B/A Unilever Concentrated fatty acyl amido surfactant compositions
US9878056B2 (en) * 2012-04-02 2018-01-30 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
US9467516B2 (en) 2013-07-01 2016-10-11 Electronics And Telecommunications Research Institute Method and apparatus for managing resource

Also Published As

Publication number Publication date
EP3347031B1 (en) 2021-01-27
WO2017044367A1 (en) 2017-03-16
US10633459B2 (en) 2020-04-28
EP3347031B8 (en) 2021-04-28
KR20180051543A (ko) 2018-05-16
JP6883569B2 (ja) 2021-06-09
US20180237544A1 (en) 2018-08-23
EP3347031A1 (en) 2018-07-18
CN108025033A (zh) 2018-05-11
US20180305467A1 (en) 2018-10-25
US10647782B2 (en) 2020-05-12
BR112018004717A2 (pt) 2018-09-25
JP2018528956A (ja) 2018-10-04
CN108025033B (zh) 2022-02-22

Similar Documents

Publication Publication Date Title
DK3676297T3 (da) Forbindelser, sammensætninger og fremgangsmåder
DK3307707T3 (da) Halogensubstituerede phenoxyphenylamidiner og anvendelsen deraf som fungicider
DK3495023T3 (da) Semifluorerede forbindelser og sammensætninger deraf
DK3310371T3 (da) Glucagon og GLP-1-Co-agonistforbindelser
DK3316909T5 (da) Anti-ntb-a-antistoffer og relaterede sammensætninger og fremgangsmåder
DK3368655T3 (da) Forbedret proteinekspression og fremgangsmåder dertil
DK3395801T3 (da) Arylazolforbindelse og skadedyrsbekæmpelsesmiddel
DK3102200T3 (da) Terapeutisk forbindelse og sammensætning
DK3347031T3 (da) Sammensætning, der omfatter et protein og en polyalkoxyfedtforbindelse
DK3128005T3 (da) Sirp-alfa-variantkonstruktioner og anvendelser deraf
DK3357343T3 (da) Fedtsammensætning og fremgangsmåde til fremstilling heraf
DK3259358T3 (da) Forøget proteinekspression
DK3582629T3 (da) Marinade
DK3130669T3 (da) Ny bakteriophag og sammensætning omfattende denne
DK3365321T3 (da) Solabegron-zwitterion og anvendelser deraf
DK3386956T3 (da) Fumagillolderivater og polymorfer deraf
DK3383397T3 (da) Farmaceutiske sammensætninger indeholdende doravirin, tenofovirdisoproxilfumarat og lamivudin
DK3321279T3 (da) Exenatidmodificeringsmiddel og anvendelse deraf
DK3337506T3 (da) Kombinationer og anvendelser deraf
DK3166960T3 (da) Lav-substituerede polymyxiner og sammensætninger deraf
DK3355702T3 (da) Sammensætning med lavt SAFA-fedtindhold, ventileret emulsion og fremgangsmåde
DK3352735T3 (da) Olanzapinformuleringer med langvarig frigivelse
DK3263133T3 (da) Pyridinonforbindelse og anvendelse deraf
DK3288933T3 (da) Oxindolforbindelser og farmaceutiske sammensætninger deraf
DK3053426T3 (da) Udbringningsskær og udbringningsko