JP2013529181A5 - - Google Patents
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- Publication number
- JP2013529181A5 JP2013529181A5 JP2013501487A JP2013501487A JP2013529181A5 JP 2013529181 A5 JP2013529181 A5 JP 2013529181A5 JP 2013501487 A JP2013501487 A JP 2013501487A JP 2013501487 A JP2013501487 A JP 2013501487A JP 2013529181 A5 JP2013529181 A5 JP 2013529181A5
- Authority
- JP
- Japan
- Prior art keywords
- pkd1
- antibody
- human mammal
- mammal
- endogenous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31759810P | 2010-03-25 | 2010-03-25 | |
| US61/317,598 | 2010-03-25 | ||
| PCT/US2011/029806 WO2011119842A1 (en) | 2010-03-25 | 2011-03-24 | Compositions and methods for treating neurological disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013529181A JP2013529181A (ja) | 2013-07-18 |
| JP2013529181A5 true JP2013529181A5 (https=) | 2014-05-08 |
Family
ID=44673620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013501487A Pending JP2013529181A (ja) | 2010-03-25 | 2011-03-24 | 神経障害を治療するための組成物および方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US9359445B2 (https=) |
| EP (1) | EP2550361B1 (https=) |
| JP (1) | JP2013529181A (https=) |
| WO (1) | WO2011119842A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2761587T3 (es) * | 2013-08-07 | 2020-05-20 | Friedrich Miescher Institute For Biomedical Res | Nuevo método de cribado para el tratamiento de la ataxia de Friedreich |
| GB201410693D0 (en) | 2014-06-16 | 2014-07-30 | Univ Southampton | Splicing modulation |
| AU2015327836B2 (en) | 2014-10-03 | 2021-07-01 | Cold Spring Harbor Laboratory | Targeted augmentation of nuclear gene output |
| CN108603230A (zh) | 2015-10-09 | 2018-09-28 | 南安普敦大学 | 基因表达的调节与蛋白质表达失调的筛选 |
| US11096956B2 (en) | 2015-12-14 | 2021-08-24 | Stoke Therapeutics, Inc. | Antisense oligomers and uses thereof |
| WO2017106377A1 (en) | 2015-12-14 | 2017-06-22 | Cold Spring Harbor Laboratory | Antisense oligomers for treatment of autosomal dominant mental retardation-5 and dravet syndrome |
| CA3053245A1 (en) * | 2017-02-09 | 2018-08-16 | Cognoa, Inc. | Platform and system for digital personalized medicine |
| US11436719B2 (en) | 2017-02-16 | 2022-09-06 | Kyoto University | Cell evaluation method, cell evaluation device, and recording medium storing cell evaluation program |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| KR102318434B1 (ko) | 2017-08-25 | 2021-11-01 | 스톡 테라퓨틱스, 인크. | 병태 및 질환 치료용 안티센스 올리고머 |
| CA3099280A1 (en) | 2018-05-04 | 2019-11-07 | Stoke Therapeutics, Inc. | Methods and compositions for treatment of cholesteryl ester storage disease |
| WO2020160156A2 (en) | 2019-01-30 | 2020-08-06 | Immutics, Inc. | Anti-gal3 antibodies and uses thereof |
| AU2020227825B2 (en) | 2019-02-27 | 2026-03-26 | Stoke Therapeutics, Inc. | Antisense oligomers for treatment of conditions and diseases |
| CN115867657A (zh) | 2020-05-11 | 2023-03-28 | 斯托克制药公司 | 用于治疗疾患和疾病的opa1反义寡聚物 |
| EP4157338A4 (en) | 2020-05-26 | 2024-11-13 | TrueBinding, Inc. | METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING |
| CN116739148A (zh) * | 2023-05-17 | 2023-09-12 | 北京海卓飞网络科技有限公司 | 面向社交网络的用户关系分析方法、装置、设备及介质 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2061416T3 (es) | 1990-10-12 | 1997-03-01 | Max Planck Gesellschaft | Ribozimas modificadas. |
| DE4216134A1 (de) | 1991-06-20 | 1992-12-24 | Europ Lab Molekularbiolog | Synthetische katalytische oligonukleotidstrukturen |
| US5652094A (en) | 1992-01-31 | 1997-07-29 | University Of Montreal | Nucleozymes |
| DE69333930T8 (de) | 1993-01-22 | 2007-02-22 | The Regents Of The University Of Colorado, Boulder | Lokalisierung von therapeutischen mitteln |
| US5627053A (en) | 1994-03-29 | 1997-05-06 | Ribozyme Pharmaceuticals, Inc. | 2'deoxy-2'-alkylnucleotide containing nucleic acid |
| US5716824A (en) | 1995-04-20 | 1998-02-10 | Ribozyme Pharmaceuticals, Inc. | 2'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic acids (ribozymes) |
| US7964598B2 (en) | 1995-10-17 | 2011-06-21 | The J. David Gladstone Institutes | ApoE4 domain interaction inhibitors and methods of use thereof |
| WO1997026270A2 (en) | 1996-01-16 | 1997-07-24 | Ribozyme Pharmaceuticals, Inc. | Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules |
| US5849902A (en) | 1996-09-26 | 1998-12-15 | Oligos Etc. Inc. | Three component chimeric antisense oligonucleotides |
| DE19650758C1 (de) * | 1996-12-06 | 1998-01-02 | Deutsches Krebsforsch | PKD1-Fragmente mit Bindungsregionen für PKD1-spezifische Antikörper |
| US6124272A (en) * | 1999-04-09 | 2000-09-26 | Isis Pharmaceutical Inc. | Antisense modulation of PDK-1 expression |
| US7491805B2 (en) | 2001-05-18 | 2009-02-17 | Sirna Therapeutics, Inc. | Conjugates and compositions for cellular delivery |
| US20050233329A1 (en) | 2002-02-20 | 2005-10-20 | Sirna Therapeutics, Inc. | Inhibition of gene expression using duplex forming oligonucleotides |
| US20050282188A1 (en) | 2001-05-18 | 2005-12-22 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
| AU2004266311B2 (en) | 2001-05-18 | 2009-07-23 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
| GB0117326D0 (en) | 2001-07-16 | 2001-09-05 | Univ Aberdeen | Napthoquinone-type inhibitors of protein aggregation |
| IL160701A0 (en) | 2001-09-21 | 2004-08-31 | Mitsubishi Pharma Corp | 3-substituted-4-pyrimidone derivatives |
| US20040121407A1 (en) * | 2002-09-06 | 2004-06-24 | Elixir Pharmaceuticals, Inc. | Regulation of the growth hormone/IGF-1 axis |
| US20060004043A1 (en) | 2003-11-19 | 2006-01-05 | Bhagwat Shripad S | Indazole compounds and methods of use thereof |
| UA95244C2 (ru) | 2005-06-22 | 2011-07-25 | Плексикон, Инк. | Соединения и способ модулирования активности киназ, и показания для их применения |
| GB0602178D0 (en) * | 2006-02-03 | 2006-03-15 | Merck Sharp & Dohme | Therapeutic treatment |
| JP2009534458A (ja) | 2006-04-26 | 2009-09-24 | キャンサー・リサーチ・テクノロジー・リミテッド | アミノ−エチル−アミノ−アリール（ａｅａａ）化合物およびそれらの使用 |
| US20090175852A1 (en) | 2006-06-06 | 2009-07-09 | Schering Corporation | Imidazopyrazines as protein kinase inhibitors |
| US8240498B2 (en) | 2006-10-31 | 2012-08-14 | Crown Packaging Technology, Inc. | Resealable closure |
| US8618063B2 (en) * | 2008-04-09 | 2013-12-31 | The Board Of Trustees Of The University Of Illinois | Method for treating a synucleinopathy |
| EP2297311A1 (en) * | 2008-06-06 | 2011-03-23 | Medizinische Universität Graz | Compounds reducing or inhibiting the expression of pkd1 for diagnosis and therapy of brain tumors |
| ES2385276B1 (es) | 2010-02-25 | 2013-07-05 | Universidad Del País Vasco | Compuestos para el tratamiento de alzheimer. |
-
2011
- 2011-03-24 JP JP2013501487A patent/JP2013529181A/ja active Pending
- 2011-03-24 WO PCT/US2011/029806 patent/WO2011119842A1/en not_active Ceased
- 2011-03-24 EP EP11760223.5A patent/EP2550361B1/en not_active Not-in-force
-
2012
- 2012-09-24 US US13/625,597 patent/US9359445B2/en not_active Expired - Fee Related
-
2016
- 2016-05-05 US US15/147,814 patent/US20160354372A1/en not_active Abandoned
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