JP2013528386A5 - - Google Patents
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- Publication number
- JP2013528386A5 JP2013528386A5 JP2013513156A JP2013513156A JP2013528386A5 JP 2013528386 A5 JP2013528386 A5 JP 2013528386A5 JP 2013513156 A JP2013513156 A JP 2013513156A JP 2013513156 A JP2013513156 A JP 2013513156A JP 2013528386 A5 JP2013528386 A5 JP 2013528386A5
- Authority
- JP
- Japan
- Prior art keywords
- cdc
- xhx3
- substrate
- assay device
- lactamase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 18
- 238000003556 assay Methods 0.000 claims 12
- 244000052616 bacterial pathogen Species 0.000 claims 12
- 230000001580 bacterial effect Effects 0.000 claims 11
- 239000000758 substrate Substances 0.000 claims 9
- 108090000204 Dipeptidase 1 Proteins 0.000 claims 8
- 102000006635 beta-lactamase Human genes 0.000 claims 8
- 239000012472 biological sample Substances 0.000 claims 7
- 150000001875 compounds Chemical class 0.000 claims 7
- 230000001225 therapeutic effect Effects 0.000 claims 7
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 239000007850 fluorescent dye Substances 0.000 claims 4
- UPSFMJHZUCSEHU-JYGUBCOQSA-N n-[(2s,3r,4r,5s,6r)-2-[(2r,3s,4r,5r,6s)-5-acetamido-4-hydroxy-2-(hydroxymethyl)-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide Chemical compound CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@H](O)[C@@H](NC(C)=O)[C@H](OC=2C=C3OC(=O)C=C(C)C3=CC=2)O[C@@H]1CO UPSFMJHZUCSEHU-JYGUBCOQSA-N 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 3
- 238000003384 imaging method Methods 0.000 claims 3
- 230000003389 potentiating effect Effects 0.000 claims 3
- 241000606125 Bacteroides Species 0.000 claims 2
- 241000193403 Clostridium Species 0.000 claims 2
- 241000588722 Escherichia Species 0.000 claims 2
- 241000606790 Haemophilus Species 0.000 claims 2
- 241000589248 Legionella Species 0.000 claims 2
- 208000007764 Legionnaires' Disease Diseases 0.000 claims 2
- 241000186781 Listeria Species 0.000 claims 2
- 241000186359 Mycobacterium Species 0.000 claims 2
- 241001502334 Mycobacterium avium complex bacterium Species 0.000 claims 2
- 241001302239 Mycobacterium tuberculosis complex Species 0.000 claims 2
- 241000589516 Pseudomonas Species 0.000 claims 2
- 241000607142 Salmonella Species 0.000 claims 2
- 241000607768 Shigella Species 0.000 claims 2
- 241000191940 Staphylococcus Species 0.000 claims 2
- 241000194017 Streptococcus Species 0.000 claims 2
- 229960002685 biotin Drugs 0.000 claims 2
- 235000020958 biotin Nutrition 0.000 claims 2
- 239000011616 biotin Substances 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 230000004963 pathophysiological condition Effects 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 241000894007 species Species 0.000 claims 2
- 108090001008 Avidin Proteins 0.000 claims 1
- 208000002151 Pleural effusion Diseases 0.000 claims 1
- 206010036790 Productive cough Diseases 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000003593 chromogenic compound Substances 0.000 claims 1
- 238000004624 confocal microscopy Methods 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 238000001506 fluorescence spectroscopy Methods 0.000 claims 1
- 239000011859 microparticle Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000003802 sputum Anatomy 0.000 claims 1
- 208000024794 sputum Diseases 0.000 claims 1
- 201000008827 tuberculosis Diseases 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/802,340 US20110020240A1 (en) | 2008-08-06 | 2010-06-04 | Use of bacterial beta-lactamase for in vitro diagnostics and in vivo imaging, diagnostics and therapeutics |
| US12/802,340 | 2010-06-04 | ||
| PCT/US2011/001018 WO2011152883A2 (en) | 2010-06-04 | 2011-06-03 | Use of bacterial beta-lactamase for in vitro diagnostics and in vivo imaging, diagnostics and therapeutics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013528386A JP2013528386A (ja) | 2013-07-11 |
| JP2013528386A5 true JP2013528386A5 (enExample) | 2014-07-17 |
Family
ID=45067221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013513156A Pending JP2013528386A (ja) | 2010-06-04 | 2011-06-03 | インビトロ診断、および、インビボ画像化、診断、ならびに、治療のための細菌β−ラクタマーゼの使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20110020240A1 (enExample) |
| EP (1) | EP2585611A4 (enExample) |
| JP (1) | JP2013528386A (enExample) |
| KR (1) | KR20130132722A (enExample) |
| CN (1) | CN103038359A (enExample) |
| AU (1) | AU2011262374A1 (enExample) |
| CA (1) | CA2801299A1 (enExample) |
| RU (1) | RU2012157279A (enExample) |
| WO (1) | WO2011152883A2 (enExample) |
| ZA (1) | ZA201300050B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050227309A1 (en) * | 2004-01-21 | 2005-10-13 | Corry Schuyler B | Optically-detectable enzyme substrates and their method of use |
| EP2823050B1 (en) * | 2012-03-08 | 2017-03-01 | Julius-Maximilians-Universität Würzburg | Diagnostic chewing gum for pathogens |
| CN102633742A (zh) * | 2012-03-22 | 2012-08-15 | 盛世泰科生物医药技术(苏州)有限公司 | 一种2-(6-羟基苯并[d]噻唑-2-基)噻唑-4-羧酸钠的合成方法 |
| CN103360385A (zh) * | 2012-04-06 | 2013-10-23 | 上海交通大学医学院附属第三人民医院 | 一种治疗mrsa感染的化合物和药物 |
| US9677112B2 (en) * | 2012-05-15 | 2017-06-13 | The Texas A&M University System | β-lactamase substrates and methods of their use for the diagnosis of tuberculosis |
| US11268958B2 (en) | 2012-09-14 | 2022-03-08 | The Johns Hopkins University | Bacteria-specific labeled substrtates as imaging biomarkers to diagnose, locate, and monitor infections |
| CN104714006B (zh) * | 2015-02-04 | 2017-10-20 | 国家纳米科学中心 | 一种检测奶制品中β‑内酰胺酶的方法 |
| CN104697970A (zh) * | 2015-03-17 | 2015-06-10 | 华中科技大学同济医学院附属协和医院 | 一种三维重建观察细胞在载体内增殖分布的方法 |
| CN107703130A (zh) * | 2017-09-19 | 2018-02-16 | 淮海工学院 | 适用于检测牛奶中残留的β‑内酰胺酶的色差检测方法 |
| CN110551497B (zh) * | 2019-09-15 | 2022-06-10 | 四川农业大学 | 一种分子印迹量子点磷光探针的制备方法及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5407957A (en) * | 1990-02-13 | 1995-04-18 | Martek Corporation | Production of docosahexaenoic acid by dinoflagellates |
| US5338843A (en) * | 1992-01-30 | 1994-08-16 | Becton, Dickinson And Company | Fluorogenic and chromogenic β-lactamase substrates |
| US7427680B2 (en) * | 2001-01-12 | 2008-09-23 | The Regents Of The University Of California | Fluorogenic substrates for BETA-lactamase gene expression |
| US6166231A (en) * | 1998-12-15 | 2000-12-26 | Martek Biosciences Corporation | Two phase extraction of oil from biomass |
| SE0302840D0 (sv) * | 2003-10-29 | 2003-10-29 | Affibody Ab | Detection method |
| US20070048848A1 (en) * | 2005-08-25 | 2007-03-01 | Sunsource Industries | Method, apparatus and system for biodiesel production from algae |
| BRPI0917478A8 (pt) * | 2008-08-06 | 2017-05-23 | Univ Leland Stanford Junior | uso de beta-lactamase bacteriana para diagnóstico in vitroe geração de imagem, diagnóstico e terapêutica in vivo |
-
2010
- 2010-06-04 US US12/802,340 patent/US20110020240A1/en not_active Abandoned
-
2011
- 2011-06-03 KR KR1020137000204A patent/KR20130132722A/ko not_active Withdrawn
- 2011-06-03 EP EP20110790116 patent/EP2585611A4/en not_active Withdrawn
- 2011-06-03 JP JP2013513156A patent/JP2013528386A/ja active Pending
- 2011-06-03 CN CN2011800335438A patent/CN103038359A/zh active Pending
- 2011-06-03 AU AU2011262374A patent/AU2011262374A1/en not_active Abandoned
- 2011-06-03 WO PCT/US2011/001018 patent/WO2011152883A2/en not_active Ceased
- 2011-06-03 RU RU2012157279/10A patent/RU2012157279A/ru unknown
- 2011-06-03 CA CA2801299A patent/CA2801299A1/en not_active Abandoned
-
2013
- 2013-01-03 ZA ZA2013/00050A patent/ZA201300050B/en unknown
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