BRPI0917478A8 - uso de beta-lactamase bacteriana para diagnóstico in vitroe geração de imagem, diagnóstico e terapêutica in vivo - Google Patents

uso de beta-lactamase bacteriana para diagnóstico in vitroe geração de imagem, diagnóstico e terapêutica in vivo

Info

Publication number
BRPI0917478A8
BRPI0917478A8 BRPI0917478A BRPI0917478A BRPI0917478A8 BR PI0917478 A8 BRPI0917478 A8 BR PI0917478A8 BR PI0917478 A BRPI0917478 A BR PI0917478A BR PI0917478 A BRPI0917478 A BR PI0917478A BR PI0917478 A8 BRPI0917478 A8 BR PI0917478A8
Authority
BR
Brazil
Prior art keywords
diagnosis
lactamase
therapy
vivo imaging
bacterial beta
Prior art date
Application number
BRPI0917478A
Other languages
English (en)
Inventor
D Cirillo Jeffrey
Rao Jiangong
Board Of Trustees Of The Leland Stanford Junior University The
Original Assignee
Univ Leland Stanford Junior
Texas A & M Univ Sys
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior, Texas A & M Univ Sys filed Critical Univ Leland Stanford Junior
Publication of BRPI0917478A2 publication Critical patent/BRPI0917478A2/pt
Publication of BRPI0917478A8 publication Critical patent/BRPI0917478A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
BRPI0917478A 2008-08-06 2009-08-06 uso de beta-lactamase bacteriana para diagnóstico in vitroe geração de imagem, diagnóstico e terapêutica in vivo BRPI0917478A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18811208P 2008-08-06 2008-08-06
US20360508P 2008-12-24 2008-12-24
PCT/US2009/004503 WO2010016911A2 (en) 2008-08-06 2009-08-06 Use of bacterial beta-lactamase for in vitro diagnostics and in vivo imaging, diagnostics and therapeutics

Publications (2)

Publication Number Publication Date
BRPI0917478A2 BRPI0917478A2 (pt) 2015-12-01
BRPI0917478A8 true BRPI0917478A8 (pt) 2017-05-23

Family

ID=41664121

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0917478A BRPI0917478A8 (pt) 2008-08-06 2009-08-06 uso de beta-lactamase bacteriana para diagnóstico in vitroe geração de imagem, diagnóstico e terapêutica in vivo

Country Status (15)

Country Link
US (1) US20100047172A1 (pt)
EP (1) EP2318834A4 (pt)
JP (1) JP5696947B2 (pt)
KR (1) KR20110081147A (pt)
CN (1) CN102369440B (pt)
AU (1) AU2009280078B2 (pt)
BR (1) BRPI0917478A8 (pt)
CA (1) CA2732748A1 (pt)
IL (2) IL211063A0 (pt)
MX (1) MX2011001423A (pt)
NZ (1) NZ591099A (pt)
RU (1) RU2520661C2 (pt)
SG (1) SG10201408809XA (pt)
WO (1) WO2010016911A2 (pt)
ZA (1) ZA201101151B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110020240A1 (en) * 2008-08-06 2011-01-27 Cirillo Jeffrey D Use of bacterial beta-lactamase for in vitro diagnostics and in vivo imaging, diagnostics and therapeutics
FR2956868B1 (fr) 2010-03-01 2014-01-10 Bio Rad Pasteur Procede rapide de detection d'enzymes et de microorganismes
US9173966B2 (en) 2012-01-17 2015-11-03 The Regents Of The University Of California Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof
CN103360385A (zh) * 2012-04-06 2013-10-23 上海交通大学医学院附属第三人民医院 一种治疗mrsa感染的化合物和药物
CN103509083B (zh) * 2012-06-28 2016-06-08 王郁生 一种广谱β-内酰胺酶荧光底物及其制备方法和应用
CN103512871B (zh) * 2012-06-28 2017-04-12 上海百可生物科技股份有限公司 一种细菌耐药性荧光检测方法及其诊断试剂盒
JP6769949B2 (ja) * 2014-07-24 2020-10-14 ユニバーシティー ヘルス ネットワーク 診断目的のためのデータの収集および解析
EP3247802B1 (en) * 2015-01-22 2024-08-28 The Board of Trustees of the Leland Stanford Junior University Protease-activated contrast agents for in vivo imaging
CN104714006B (zh) * 2015-02-04 2017-10-20 国家纳米科学中心 一种检测奶制品中β‑内酰胺酶的方法
JP7064732B2 (ja) * 2016-10-27 2022-05-11 ネクスジェン株式会社 最適化された標識を用いて特異的に発現する遺伝子を同定する方法
EP3551046B1 (en) 2016-12-07 2023-07-19 Biora Therapeutics, Inc. Gastrointestinal tract detection methods, devices and systems
CN111458313A (zh) * 2020-04-07 2020-07-28 上海交通大学医学院附属仁济医院 基于荧光d型氨基酸代谢标记的抗菌药敏试验检测方法
CN111638197B (zh) * 2020-05-25 2022-10-21 南京工业大学 一种检测β-内酰胺酶的探针及其在荧光检测耐药菌上的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2916433A1 (de) * 1979-04-24 1980-11-13 Hoechst Ag Chromophore cephalosporine und verfahren zu ihrer herstellung
US5338843A (en) * 1992-01-30 1994-08-16 Becton, Dickinson And Company Fluorogenic and chromogenic β-lactamase substrates
RU2117045C1 (ru) * 1992-03-20 1998-08-10 Санкт-Петербургский научно-исследовательский институт фтизиопульмонологии Способ определения микобактериальной бета-лактамазы
US5741657A (en) * 1995-03-20 1998-04-21 The Regents Of The University Of California Fluorogenic substrates for β-lactamase and methods of use

Also Published As

Publication number Publication date
IL234782A0 (en) 2014-11-30
NZ591099A (en) 2013-10-25
JP2011530285A (ja) 2011-12-22
IL211063A0 (en) 2011-04-28
US20100047172A1 (en) 2010-02-25
RU2011108545A (ru) 2012-09-20
WO2010016911A3 (en) 2010-06-24
KR20110081147A (ko) 2011-07-13
EP2318834A2 (en) 2011-05-11
CN102369440A (zh) 2012-03-07
EP2318834A4 (en) 2013-06-19
JP5696947B2 (ja) 2015-04-08
AU2009280078B2 (en) 2015-07-02
ZA201101151B (en) 2012-08-29
WO2010016911A2 (en) 2010-02-11
CA2732748A1 (en) 2010-02-11
MX2011001423A (es) 2011-04-27
BRPI0917478A2 (pt) 2015-12-01
SG10201408809XA (en) 2015-03-30
RU2520661C2 (ru) 2014-06-27
CN102369440B (zh) 2016-02-17
AU2009280078A1 (en) 2010-02-11

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B25G Requested change of headquarter approved

Owner name: THE TEXAS A AND M UNIVERSITY SYSTEM (US) , THE BOA

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2383 DE 06/09/2016.