JP2013527437A5 - - Google Patents
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- Publication number
- JP2013527437A5 JP2013527437A5 JP2013504499A JP2013504499A JP2013527437A5 JP 2013527437 A5 JP2013527437 A5 JP 2013527437A5 JP 2013504499 A JP2013504499 A JP 2013504499A JP 2013504499 A JP2013504499 A JP 2013504499A JP 2013527437 A5 JP2013527437 A5 JP 2013527437A5
- Authority
- JP
- Japan
- Prior art keywords
- concentration
- subject
- ccl8
- rheumatoid arthritis
- test sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 21
- 102100034871 C-C motif chemokine 8 Human genes 0.000 claims 19
- 101000946794 Homo sapiens C-C motif chemokine 8 Proteins 0.000 claims 19
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 19
- 239000012634 fragment Substances 0.000 claims 5
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- VKUYLANQOAKALN-UHFFFAOYSA-N 2-[benzyl-(4-methoxyphenyl)sulfonylamino]-n-hydroxy-4-methylpentanamide Chemical compound C1=CC(OC)=CC=C1S(=O)(=O)N(C(CC(C)C)C(=O)NO)CC1=CC=CC=C1 VKUYLANQOAKALN-UHFFFAOYSA-N 0.000 claims 3
- 102100030416 Stromelysin-1 Human genes 0.000 claims 3
- 101710108790 Stromelysin-1 Proteins 0.000 claims 3
- 238000004128 high performance liquid chromatography Methods 0.000 claims 3
- 239000003550 marker Substances 0.000 claims 3
- 238000004949 mass spectrometry Methods 0.000 claims 3
- 210000002966 serum Anatomy 0.000 claims 3
- 238000000539 two dimensional gel electrophoresis Methods 0.000 claims 3
- 238000003745 diagnosis Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 238000010171 animal model Methods 0.000 claims 1
- 230000000052 comparative effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 229940124598 therapeutic candidate Drugs 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32502710P | 2010-04-16 | 2010-04-16 | |
| US61/325,027 | 2010-04-16 | ||
| PCT/JP2011/059226 WO2011129382A1 (en) | 2010-04-16 | 2011-04-07 | Methods and reagents for diagnosing rheumatoid arthritis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013527437A JP2013527437A (ja) | 2013-06-27 |
| JP2013527437A5 true JP2013527437A5 (cg-RX-API-DMAC7.html) | 2014-08-28 |
| JP5786020B2 JP5786020B2 (ja) | 2015-09-30 |
Family
ID=44788487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013504499A Expired - Fee Related JP5786020B2 (ja) | 2010-04-16 | 2011-04-07 | 関節リウマチを診断する方法および試薬 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US9528998B2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5786020B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011129382A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5786020B2 (ja) | 2010-04-16 | 2015-09-30 | アボットジャパン株式会社 | 関節リウマチを診断する方法および試薬 |
| US10723794B2 (en) * | 2015-03-18 | 2020-07-28 | University Of South Carolina | Anti-CcL8 antibodies and uses thereof |
| KR101801092B1 (ko) | 2016-01-28 | 2017-11-28 | 순천향대학교 산학협력단 | 특발성 페섬유증 진단용 마커 조성물 및 특발성 폐섬유증 진단을 위한 정보제공방법 |
| WO2018021624A1 (ko) * | 2016-07-29 | 2018-02-01 | 가톨릭대학교 산학협력단 | 류마티스 관절염 진단용 바이오마커 |
| EP4467565A3 (en) | 2016-12-21 | 2025-03-12 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| WO2018232288A1 (en) * | 2017-06-16 | 2018-12-20 | Genentech, Inc. | Diagnostic and therapeutic methods for irak4-mediated disorders and conditions |
| US11138880B2 (en) | 2017-09-29 | 2021-10-05 | 3M Innovative Properties Company | Vehicle-sourced infrastructure quality metrics |
| FR3072779A1 (fr) * | 2017-10-19 | 2019-04-26 | Sinnovial | Procede d'estimation de l'efficacite d'un modulateur de la costimulation des lymphocytes t contre la polyarthrite rhumatoide apres reponse inadequate a une biotherapie |
| CN109142555A (zh) * | 2018-05-21 | 2019-01-04 | 深圳天祥质量技术服务有限公司 | 塑料或皮革制品中mccp的测试方法 |
| JP7789336B2 (ja) * | 2020-06-04 | 2025-12-22 | 学校法人帝京大学 | 関節リウマチの検出方法 |
| CN113049814A (zh) * | 2021-03-26 | 2021-06-29 | 南昌大学第二附属医院 | 血清中类风湿关节炎标志物检测试剂的用途及诊断试剂盒 |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| EP0273115B1 (en) | 1986-10-22 | 1994-09-07 | Abbott Laboratories | Chemiluminescent acridinium and phenanthridinium salts |
| US5006309A (en) | 1988-04-22 | 1991-04-09 | Abbott Laboratories | Immunoassay device with liquid transfer between wells by washing |
| US5089424A (en) | 1988-06-14 | 1992-02-18 | Abbott Laboratories | Method and apparatus for heterogeneous chemiluminescence assay |
| US5241070A (en) | 1988-09-26 | 1993-08-31 | Ciba Corning Diagnostics Corp. | Nucleophilic polysubstituted aryl acridinium esters and uses thereof |
| US5063081A (en) | 1988-11-14 | 1991-11-05 | I-Stat Corporation | Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| CA2048302A1 (en) | 1990-08-15 | 1992-02-16 | Victoria P. Meucci | Solubilization reagent for biological test samples |
| US5135875A (en) | 1990-08-15 | 1992-08-04 | Abbott Laboratories | Protein precipitation reagent |
| WO1992005282A1 (en) | 1990-09-14 | 1992-04-02 | Biosite Diagnostics, Inc. | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| JPH085920B2 (ja) * | 1991-01-21 | 1996-01-24 | 富士薬品工業株式会社 | 抗ヒトストロムライシンモノクローナル抗体及び酵素免疫測定法 |
| CA2107899A1 (en) | 1991-04-10 | 1992-10-11 | Gunars Edwin Valkirs | Novel conjugates and assays for simultaneous detection of multiple ligands |
| ATE177841T1 (de) | 1991-04-10 | 1999-04-15 | Biosite Diagnostics Inc | ''crosstalk''- oder übersprech-inhibitoren und ihre verwendung |
| CA2069530A1 (en) | 1991-06-03 | 1992-12-04 | Cass J. Grandone | Reagent pack for immunoassays |
| EP0649533B1 (en) | 1992-03-30 | 2000-05-10 | Abbott Laboratories | Reagents and methods for the detection and quantification of thyroxine in fluid samples |
| US5352803A (en) | 1992-03-30 | 1994-10-04 | Abbott Laboratories | 5(6)-methyl substituted fluorescein derivatives |
| US6019944A (en) | 1992-05-21 | 2000-02-01 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
| US6113855A (en) | 1996-11-15 | 2000-09-05 | Biosite Diagnostics, Inc. | Devices comprising multiple capillarity inducing surfaces |
| US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
| US6303321B1 (en) | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
| SG144731A1 (en) | 2000-07-18 | 2008-08-28 | Correlogic Systems Inc | A process for discriminating between biological states based on hidden patterns from biological data |
| US6890763B2 (en) | 2001-04-30 | 2005-05-10 | Syn X Pharma, Inc. | Biopolymer marker indicative of disease state having a molecular weight of 1350 daltons |
| WO2003048083A2 (en) * | 2001-11-30 | 2003-06-12 | Biogen Idec Ma Inc. | Antibodies against monocyte chemotactic proteins |
| US20030224386A1 (en) * | 2001-12-19 | 2003-12-04 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of rheumatoid arthritis |
| US7419821B2 (en) | 2002-03-05 | 2008-09-02 | I-Stat Corporation | Apparatus and methods for analyte measurement and immunoassay |
| US6989100B2 (en) | 2002-05-09 | 2006-01-24 | Ppd Biomarker Discovery Sciences, Llc | Methods for time-alignment of liquid chromatography-mass spectrometry data |
| US20040009503A1 (en) * | 2002-07-03 | 2004-01-15 | Molecular Staging, Inc. | Immune modulatory activity of human ribonucleases |
| US20040018577A1 (en) | 2002-07-29 | 2004-01-29 | Emerson Campbell John Lewis | Multiple hybrid immunoassay |
| AU2003294290A1 (en) * | 2002-11-15 | 2004-06-15 | Morehouse School Of Medicine | Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation. |
| WO2004067778A2 (en) * | 2003-01-28 | 2004-08-12 | University Of South Florida | Differentially expressed genes in large granular lymphocyte leukemia |
| CA2536354C (en) | 2003-07-09 | 2013-08-13 | Shionogi & Co., Ltd. | Atopic dermatitis inducer |
| US7723099B2 (en) | 2003-09-10 | 2010-05-25 | Abbott Point Of Care Inc. | Immunoassay device with immuno-reference electrode |
| US7682833B2 (en) | 2003-09-10 | 2010-03-23 | Abbott Point Of Care Inc. | Immunoassay device with improved sample closure |
| CA2552425C (en) * | 2004-02-27 | 2018-02-06 | F. Hoffmann-La Roche Ag | Method of assessing rheumatoid arthritis by measuring rheumatoid factor and interleukin-6 |
| US20070099239A1 (en) | 2005-06-24 | 2007-05-03 | Raymond Tabibiazar | Methods and compositions for diagnosis and monitoring of atherosclerotic cardiovascular disease |
| US20080026485A1 (en) * | 2006-04-18 | 2008-01-31 | Wolfgang Hueber | Antibody profiling for determination of patient responsiveness |
| US7883855B2 (en) | 2006-07-21 | 2011-02-08 | Abbott Laboratories | Immunosuppressant drug extraction reagent for immunoassays |
| EP2074428B1 (en) * | 2006-09-29 | 2015-07-01 | Roche Diagnostics GmbH | Assessing the risk of disease progression for a patient with rheumatoid arthritis |
| US7906293B2 (en) | 2007-04-09 | 2011-03-15 | Abbott Laboratories | Acridinium phenyl esters useful in the analysis of biological |
| DK2142515T3 (da) * | 2007-04-18 | 2014-06-23 | Probiodrug Ag | Nitrovinyl-diaminderivater som glutaminyl-cyclase-inhibitorer |
| US20100183586A1 (en) | 2007-06-22 | 2010-07-22 | Tsukasa Hori | Method for detection or treatment of graft versus host disease |
| CN102272600A (zh) | 2008-12-31 | 2011-12-07 | 雅培医护站股份有限公司 | 用于使用核苷酸缀合物的免疫测定的方法和设备 |
| JP5786020B2 (ja) | 2010-04-16 | 2015-09-30 | アボットジャパン株式会社 | 関節リウマチを診断する方法および試薬 |
-
2011
- 2011-04-07 JP JP2013504499A patent/JP5786020B2/ja not_active Expired - Fee Related
- 2011-04-07 WO PCT/JP2011/059226 patent/WO2011129382A1/en not_active Ceased
- 2011-04-14 US US13/086,528 patent/US9528998B2/en not_active Expired - Fee Related
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