JP2013525820A5 - - Google Patents

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JP2013525820A5
JP2013525820A5 JP2013509303A JP2013509303A JP2013525820A5 JP 2013525820 A5 JP2013525820 A5 JP 2013525820A5 JP 2013509303 A JP2013509303 A JP 2013509303A JP 2013509303 A JP2013509303 A JP 2013509303A JP 2013525820 A5 JP2013525820 A5 JP 2013525820A5
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healthy volunteers
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average
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JP2013509303A
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JP2013525820A (ja
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Priority claimed from PCT/US2011/035584 external-priority patent/WO2011140484A1/en
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JP2013509303A 2010-05-06 2011-05-06 関節リウマチの発症に関するリスクを診断し、病期分類し、予測し、治療レスポンダーを同定するための方法 Pending JP2013525820A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US33208110P 2010-05-06 2010-05-06
US61/332,081 2010-05-06
US201061428500P 2010-12-30 2010-12-30
US61/428,500 2010-12-30
US201161444702P 2011-02-19 2011-02-19
US61/444,702 2011-02-19
PCT/US2011/035584 WO2011140484A1 (en) 2010-05-06 2011-05-06 Methods for diagnosing, staging, predicting risk for developing and identifying treatment responders for rheumatoid arthritis

Publications (2)

Publication Number Publication Date
JP2013525820A JP2013525820A (ja) 2013-06-20
JP2013525820A5 true JP2013525820A5 (https=) 2014-07-24

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JP2013509303A Pending JP2013525820A (ja) 2010-05-06 2011-05-06 関節リウマチの発症に関するリスクを診断し、病期分類し、予測し、治療レスポンダーを同定するための方法

Country Status (6)

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US (2) US20110301053A1 (https=)
EP (1) EP2566971B1 (https=)
JP (1) JP2013525820A (https=)
AU (1) AU2011249908A1 (https=)
CA (1) CA2798149A1 (https=)
WO (1) WO2011140484A1 (https=)

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Publication number Priority date Publication date Assignee Title
US20130261016A1 (en) * 2012-03-28 2013-10-03 Meso Scale Technologies, Llc Diagnostic methods for inflammatory disorders
ES2792227T3 (es) 2014-09-26 2020-11-10 Somalogic Inc Predicción de evento de riesgo cardiovascular y usos de la misma

Family Cites Families (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071298A (en) 1974-06-27 1978-01-31 Stanford Research Institute Laser Raman/fluorescent device for analyzing airborne particles
DE2732272C2 (de) 1977-07-16 1979-07-05 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, 6900 Heidelberg Verfahren und Vorrichtung zur Fluoreszenzanalyse von gefärbten Partikeln, insbesondere biologischen Zellen
US4251733A (en) 1978-06-29 1981-02-17 Hirleman Jr Edwin D Technique for simultaneous particle size and velocity measurement
US4172227A (en) 1978-07-21 1979-10-23 Becton, Dickinson And Company Flow microfluorometer
US4452773A (en) 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
US4521733A (en) 1983-05-23 1985-06-04 General Electric Company NMR Imaging of the transverse relaxation time using multiple spin echo sequences
US4768879A (en) 1986-06-17 1988-09-06 The Dow Chemical Company Method for measuring the size of objects in a fluid medium
US4770183A (en) 1986-07-03 1988-09-13 Advanced Magnetics Incorporated Biologically degradable superparamagnetic particles for use as nuclear magnetic resonance imaging agents
US4988191A (en) 1987-03-09 1991-01-29 University Of Illinois Electro-optical method and system for determining the direction of motion in double-exposure velocimetry by shifting an optical image field
US5041733A (en) 1987-03-20 1991-08-20 Agency Of Industrial Science & Technology Method and apparatus for identifying chromosomes or cells
DE3720844A1 (de) 1987-06-24 1989-01-05 Stefan Miltenyi Trennsaeule fuer die magnetische separierung von zellen, zellaggregaten, und zellulaeren bestandteilen
US4793705A (en) 1987-10-07 1988-12-27 The United States Of America As Represented By The United States Department Of Energy Single molecule tracking
US4927265A (en) 1988-04-29 1990-05-22 501 Microphoretic Systems, Inc. Detector for fluorescence and absorption spectroscopy
US4972265A (en) 1988-05-06 1990-11-20 Minolta Camera Kabushiki Kaisha Electronic camera having a controllable light blocking member
US5002389A (en) 1988-12-22 1991-03-26 Honeywell Inc. Pulsed fluorescence velocimeter
US5385707A (en) 1988-12-28 1995-01-31 Stefan Miltenyi Metal matrices for use in high gradient magnetic separation of biological materials and method for coating the same
US4979824A (en) 1989-05-26 1990-12-25 Board Of Trustees Of The Leland Stanford Junior University High sensitivity fluorescent single particle and single molecule detection apparatus and method
US5108179A (en) 1989-08-09 1992-04-28 Myers Stephen A System and method for determining changes in fluorescence of stained nucleic acid in electrophoretically separated bands
US5274240A (en) 1990-01-12 1993-12-28 The Regents Of The University Of California Capillary array confocal fluorescence scanner and method
US5770029A (en) 1996-07-30 1998-06-23 Soane Biosciences Integrated electrophoretic microdevices
EP0527149B1 (en) 1990-04-11 1995-12-20 Ludwig Institute For Cancer Research Methods and apparatus allowing sequential chemical reactions
US5094594A (en) 1990-04-23 1992-03-10 Genomyx, Incorporated Piezoelectric pumping device
US5230997A (en) 1990-07-19 1993-07-27 The United States Of America As Represented By The Department Of Health And Human Services Methods of detecting the presence of human herpesvirus-7 infection
US5269937A (en) 1990-10-23 1993-12-14 Cetus Corporation HPLC light scattering detector for biopolymers
US5605662A (en) 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
US5846708A (en) 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
US5290834A (en) 1991-12-04 1994-03-01 Rohm & Haas Company Method for controlling elution rate of agent
US5209834A (en) 1992-03-09 1993-05-11 The United States Of America As Represented By The United States Department Of Energy Ordered transport and identification of particles
AU5884394A (en) 1993-01-18 1994-08-15 Evotec Biosystems Gmbh Method and device for assessing the suitability of biopolymers
GB9301122D0 (en) 1993-01-21 1993-03-10 Scient Generics Ltd Method of analysis/separation
US5547849A (en) 1993-02-17 1996-08-20 Biometric Imaging, Inc. Apparatus and method for volumetric capillary cytometry
JPH06265447A (ja) 1993-03-16 1994-09-22 Hitachi Ltd 微量反応装置およびこれを使用する微量成分測定装置
US5543838A (en) 1993-08-31 1996-08-06 Xerox Corporation Signal multiplexing system for an image sensor array
JP3290786B2 (ja) 1993-11-26 2002-06-10 シスメックス株式会社 粒子分析装置
DE4405005A1 (de) 1994-02-17 1995-08-24 Rossendorf Forschzent Mikro-Fluiddiode
US5540494A (en) 1994-06-03 1996-07-30 Purvis, Jr.; Norman B. Method and apparatus for determining absolute particle size, surface area and volume normalized fluorescence using forward angle light scatter intensity in flow cytometry
US6001229A (en) 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
US5645702A (en) 1995-06-07 1997-07-08 Hewlett-Packard Company Low voltage miniaturized column analytical apparatus and method
US5658413A (en) 1994-10-19 1997-08-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
US5571410A (en) 1994-10-19 1996-11-05 Hewlett Packard Company Fully integrated miniaturized planar liquid sample handling and analysis device
US5603351A (en) 1995-06-07 1997-02-18 David Sarnoff Research Center, Inc. Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device
US5585069A (en) 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
FI98765C (fi) 1995-01-16 1997-08-11 Erkki Soini Virtaussytometrinen menetelmä ja laite
DE19508366C2 (de) 1995-03-10 1998-01-29 Evotec Biosystems Gmbh Verfahren zum direkten Nachweisen weniger Nucleinsäurestränge
US5793485A (en) 1995-03-20 1998-08-11 Sandia Corporation Resonant-cavity apparatus for cytometry or particle analysis
US5682038A (en) 1995-04-06 1997-10-28 Becton Dickinson And Company Fluorescent-particle analyzer with timing alignment for analog pulse subtraction of fluorescent pulses arising from different excitation locations
US6991907B1 (en) 1995-04-18 2006-01-31 Biosite, Inc. Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays
DE19524572A1 (de) 1995-07-06 1997-01-09 Bayer Ag Verfahren zur Herstellung eines synthetischen Kalibrators für den Einsatz in Immunoassays, bestehend aus den Analyten oder Teilsequenzen davon, die an inerten Trägermoleküle konjugiert sind
US5798222A (en) 1995-07-17 1998-08-25 Guava Technologies, Inc. Apparatus for monitoring substances in organisms
US6132580A (en) 1995-09-28 2000-10-17 The Regents Of The University Of California Miniature reaction chamber and devices incorporating same
US5716825A (en) 1995-11-01 1998-02-10 Hewlett Packard Company Integrated nucleic acid analysis system for MALDI-TOF MS
DE19548028A1 (de) 1995-12-21 1997-06-26 Bayer Ag Verfahren zur Herstellung eines synthetischen Kalibrators für den Einsatz in Sandwich-Immunoassays, bestehend aus einem Antikörper gegen einen der im Assay benutzten Antikörper und einer Sequenz des Analyten
US5746901A (en) 1996-04-05 1998-05-05 Regents Of The University Of California Hybrid slab-microchannel gel electrophoresis system
US6399023B1 (en) 1996-04-16 2002-06-04 Caliper Technologies Corp. Analytical system and method
US5795758A (en) 1997-04-18 1998-08-18 Smithkline Beecham Corporation DNA encoding histidyl tRNA synthetase variant from Streptococcus pneumoniae
US5863801A (en) 1996-06-14 1999-01-26 Sarnoff Corporation Automated nucleic acid isolation
DE19630956A1 (de) 1996-07-31 1998-02-05 Basf Ag Verfahren und Vorrichtung zur Raman-Korrelationsspektroskopie
DE19634873A1 (de) 1996-08-29 1998-03-12 Boehringer Mannheim Gmbh System zur Unterscheidung fluoreszierender Molekülgruppen durch zeitaufgelöste Fluoreszenzmessung
DE19647927A1 (de) 1996-11-20 1998-05-28 Bayer Ag Verfahren zur Herstellung einer stabilen Troponin I Präparation und dessen Verwendung als Kalibrator in Immunoassays
DE19649048C1 (de) 1996-11-27 1998-04-09 Evotec Biosystems Gmbh Verfahren zur Unterscheidung oder Erfassung von Partikeln in einer Probe durch Identifizierung von Signalabschnitten zeitaufgelöster, optischer Rohsignale aus der Probe auf Basis von Einzelphotonendetektion
US5795158A (en) 1996-12-02 1998-08-18 Warinner; Peter Apparatus to review clinical microbiology
CN1251609A (zh) 1997-02-12 2000-04-26 尤金·Y·查恩 分析聚合物的方法和产品
CA2284870C (en) 1997-03-17 2003-11-25 Tsi Incorporated System for detecting fluorescing components in aerosols
US6235471B1 (en) 1997-04-04 2001-05-22 Caliper Technologies Corp. Closed-loop biochemical analyzers
US5985214A (en) 1997-05-16 1999-11-16 Aurora Biosciences Corporation Systems and methods for rapidly identifying useful chemicals in liquid samples
US6710871B1 (en) 1997-06-09 2004-03-23 Guava Technologies, Inc. Method and apparatus for detecting microparticles in fluid samples
GB2326229A (en) 1997-06-13 1998-12-16 Robert Jeffrey Geddes Carr Detecting and analysing submicron particles
US5989402A (en) 1997-08-29 1999-11-23 Caliper Technologies Corp. Controller/detector interfaces for microfluidic systems
US6130101A (en) 1997-09-23 2000-10-10 Molecular Probes, Inc. Sulfonated xanthene derivatives
US6143152A (en) 1997-11-07 2000-11-07 The Regents Of The University Of California Microfabricated capillary array electrophoresis device and method
US6049380A (en) 1997-11-12 2000-04-11 Regents Of The University Of California Single molecule identification using selected fluorescence characteristics
EP0965044B1 (en) 1997-11-18 2003-03-19 Bio-Rad Laboratories, Inc. Multiplex flow immunoassays with magnetic particles as solid phase
US6041515A (en) 1998-01-12 2000-03-28 Life Technologies, Inc. Apparatus for drying solutions containing macromolecules
SE9800360D0 (sv) 1998-02-06 1998-02-06 Goeteborg University Science I Method, apparatus and flow cell for high sensitivity detection of fluorescent molecules
DE19822452C2 (de) 1998-04-22 2003-02-13 Stefan Seeger Verfahren zur Bestimmung der Dichte lumineszierender Moleküle an einer Oberfläche, Verwendung des Verfahrens zur Bestimmung von Adsorptions- und Bindungskinetiken und Gleichgewichts- und Bindungskonstanten von Molekülen an einer Oberfläche durch Lumineszenz-Messungen und Vorrichtung zur Durchführung des Verfahrens
EP0955084B1 (en) 1998-04-27 2006-07-26 Corning Incorporated Method of depositing an array of biological samples using a redrawn capillary reservoir
US6689323B2 (en) 1998-10-30 2004-02-10 Agilent Technologies Method and apparatus for liquid transfer
US6361671B1 (en) 1999-01-11 2002-03-26 The Regents Of The University Of California Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels
JP2000208208A (ja) 1999-01-18 2000-07-28 Sony Corp コネクタ装置及びそれを用いた電子機器並びにプラグ
US6249341B1 (en) 1999-01-25 2001-06-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6671044B2 (en) 1999-01-25 2003-12-30 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells in broad flat flow
US6473176B2 (en) 1999-01-25 2002-10-29 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
DE19909326A1 (de) 1999-03-03 2000-09-21 Lucas Ind Plc Vorrichtung und Verfahren zum Steuern der Fahrgeschwindigkeit eines Kraftfahrzeuges
WO2000055882A1 (en) 1999-03-18 2000-09-21 Cambridge Research & Instrumentation Inc. High-efficiency multiple probe imaging system
US6242266B1 (en) 1999-04-30 2001-06-05 Agilent Technologies Inc. Preparation of biopolymer arrays
WO2000070080A1 (en) 1999-05-17 2000-11-23 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US6309886B1 (en) 1999-06-04 2001-10-30 The Regents Of The University Of California High throughput analysis of samples in flowing liquid
US6811668B1 (en) 1999-06-22 2004-11-02 Caliper Life Sciences, Inc. Apparatus for the operation of a microfluidic device
US6338746B1 (en) 1999-07-23 2002-01-15 Rlc Technologies, L.L.C. Polymer-sulfur-polymer coated fertilizers
US6532067B1 (en) 1999-08-09 2003-03-11 The United States Of America As Represented By The Secretary Of The Army Aerosol fluorescence spectrum analyzer for rapid measurement of single airborne particles
US6495104B1 (en) 1999-08-19 2002-12-17 Caliper Technologies Corp. Indicator components for microfluidic systems
US6623613B1 (en) 1999-10-01 2003-09-23 The Regents Of The University Of California Microfabricated liquid sample loading system
US6296452B1 (en) 2000-04-28 2001-10-02 Agilent Technologies, Inc. Microfluidic pumping
US20020167665A1 (en) 2000-05-19 2002-11-14 Yeung Edward S. High-throughput methods of distinguishing at least one molecule individually in a sample comprising multiple molecules and systems for use therein
US6608680B2 (en) 2000-08-25 2003-08-19 Amnis Corporation TDI imaging system for kinetic studies
EP1322710B2 (en) 2000-09-29 2015-02-18 Life Technologies Corporation Modified carbocyanine dyes and their conjugates
US6537437B1 (en) 2000-11-13 2003-03-25 Sandia Corporation Surface-micromachined microfluidic devices
US6783992B2 (en) 2001-01-03 2004-08-31 Agilent Technologies, Inc. Methods and using chemico-mechanical microvalve devices for the selective separation of components from multi-component fluid samples
EP1221678A1 (fr) 2001-01-09 2002-07-10 Telectronic SA Récepteur destiné à capter un signal électromagnétique et dispositif utilisant un tel récepteur
US6850317B2 (en) 2001-01-23 2005-02-01 Schlumberger Technology Corporation Apparatus and methods for determining velocity of oil in a flow stream
US6386219B1 (en) 2001-02-01 2002-05-14 Agilent Technologies, Inc. Fluid handling system and method of manufacture
US6949377B2 (en) 2001-03-05 2005-09-27 Ho Winston Z Chemiluminescence-based microfluidic biochip
US6802342B2 (en) 2001-04-06 2004-10-12 Fluidigm Corporation Microfabricated fluidic circuit elements and applications
ATE458199T1 (de) 2001-05-04 2010-03-15 Biosite Inc Diagnostische marker der akuten koronaren syndrome und ihre verwendungen
US20030125231A1 (en) * 2001-05-23 2003-07-03 Boehringer Ingelheim Pharmaceuticals, Inc. Methods and compounds for the diagnosis of inflammatory disease and identification of pharmacological agents useful in the treatment of inflammatory disease
US20070160576A1 (en) * 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
US6766817B2 (en) 2001-07-25 2004-07-27 Tubarc Technologies, Llc Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action
US20040219509A1 (en) 2001-08-20 2004-11-04 Biosite, Inc. Diagnostic markers of stroke and cerebral injury and methods of use thereof
US6394305B1 (en) 2001-08-31 2002-05-28 Beverly Sydlosky Food holder and lifter with adjustable handles
US6867005B2 (en) 2001-10-24 2005-03-15 Beckman Coulter, Inc. Method and apparatus for increasing the dynamic range and accuracy of binding assays
CA2463420A1 (en) 2001-10-24 2003-05-01 Singulex, Inc. Methods for detecting genetic haplotypes by interaction with probes
US6599436B1 (en) 2001-12-06 2003-07-29 Sandia Corporation Formation of interconnections to microfluidic devices
WO2003088294A2 (en) 2002-04-11 2003-10-23 Bristol-Myers Squibb Company Mass spectrometer autosampler
MXPA03004105A (es) 2002-05-14 2004-10-15 Hoffmann La Roche Elaboracion de una prognosis en casos de enfermedad cardiaca usando una combinacion de marcadores.
WO2005005666A1 (en) 2002-11-19 2005-01-20 Singulex, Inc. Detection of target molecules through interaction with probes
WO2004059293A2 (en) 2002-12-24 2004-07-15 Biosite Incorporated Markers for differential diagnosis and methods of use thereof
WO2004066185A1 (en) 2003-01-23 2004-08-05 U.S. Genomics, Inc. Methods for analyzing polymer populations
FI20030652A0 (fi) 2003-04-30 2003-04-30 Susann Eriksson Parannettu immunomääritys
US7074194B2 (en) 2003-05-19 2006-07-11 Ischemia Technologies, Inc. Apparatus and method for risk stratification of patients with chest pain of suspected cardiac origin
PL2784084T5 (pl) * 2003-07-08 2024-12-02 Novartis Pharma Ag Przeciwciała antagonistyczne heterologicznych polipeptydów il-17a/f
US7547518B2 (en) 2003-08-19 2009-06-16 Becton, Dickinson And Company Method of screening endothelial cells for angiogenic capability
EP2287616A1 (en) * 2003-09-15 2011-02-23 Oklahoma Medical Research Foundation Method of using cytokine assays to diagnose, treat, and evaluate systemic lupus erythematosus
CA2547072C (en) 2003-11-26 2015-06-23 Applera Corporation Single nucleotide polymorphisms associated with cardiovascular disorders and statin response, methods of detection and uses thereof
WO2005089524A2 (en) 2004-03-19 2005-09-29 U.S. Genomics, Inc. Compositions and methods for detection of single molecules
US7351538B2 (en) 2004-08-23 2008-04-01 U.S. Genomics Systems and methods for detecting and analyzing polymers
US9040305B2 (en) 2004-09-28 2015-05-26 Singulex, Inc. Method of analysis for determining a specific protein in blood samples using fluorescence spectrometry
US7572640B2 (en) 2004-09-28 2009-08-11 Singulex, Inc. Method for highly sensitive detection of single protein molecules labeled with fluorescent moieties
AU2005290314A1 (en) 2004-09-28 2006-04-06 Singulex, Inc. System and method for spectroscopic analysis of single particles
US8685711B2 (en) 2004-09-28 2014-04-01 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
WO2006098772A2 (en) 2004-10-13 2006-09-21 U.S. Genomics, Inc. Systems and methods for measurement optimization
CA2596509A1 (en) * 2005-02-14 2006-08-24 Wyeth Interleukin-17f antibodies and other il-17f signaling antagonists and uses therefor
CA2623523C (en) 2005-09-28 2019-02-12 Becton, Dickinson And Company Detection of lysophosphatidylcholine for prognosis or diagnosis of a systemic inflammatory condition
US20070249533A1 (en) * 2005-09-28 2007-10-25 Levin Steven D Il-17a and il-17f antagonists and methods of using the same
US20070259377A1 (en) 2005-10-11 2007-11-08 Mickey Urdea Diabetes-associated markers and methods of use thereof
EP1987058B1 (en) 2006-02-10 2010-05-12 ZymoGenetics, Inc. Soluble il-17rcx4 and methods of using in inflammation
CA2648385C (en) 2006-04-04 2020-09-01 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
US7838250B1 (en) 2006-04-04 2010-11-23 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
EP1887361A1 (en) 2006-08-07 2008-02-13 Bio-Rad Pasteur Method for the prediction of vascular events
CL2008000883A1 (es) * 2007-03-28 2008-10-03 Wyeth6 3 Metodo de deteccion de compuestos capaces de antagonizar la senalizacion de il-17f/il-17a; compuesto identificado por dicho metodo; uso de una cantidad de un antagonista de senalizacion de il-17f/il-17a, composicion farmaceutica que comprende dicho a
CA2709217C (en) 2007-12-19 2021-01-05 Singulex, Inc. Scanning analyzer for single molecule detection and methods of use
WO2009126380A2 (en) * 2008-03-05 2009-10-15 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
SG10201608871XA (en) * 2008-05-05 2016-12-29 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
JP2010071833A (ja) * 2008-09-19 2010-04-02 Kyoto Univ 関節リウマチ疾患の検査方法および検査用キット

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