JP2022536653A5 - - Google Patents
Info
- Publication number
- JP2022536653A5 JP2022536653A5 JP2021573215A JP2021573215A JP2022536653A5 JP 2022536653 A5 JP2022536653 A5 JP 2022536653A5 JP 2021573215 A JP2021573215 A JP 2021573215A JP 2021573215 A JP2021573215 A JP 2021573215A JP 2022536653 A5 JP2022536653 A5 JP 2022536653A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- akg
- composition according
- sasp
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962859623P | 2019-06-10 | 2019-06-10 | |
| US62/859,623 | 2019-06-10 | ||
| PCT/US2020/036974 WO2020252005A1 (en) | 2019-06-10 | 2020-06-10 | Methods and compositions for altering senescence associated secretory phenotype |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022536653A JP2022536653A (ja) | 2022-08-18 |
| JP2022536653A5 true JP2022536653A5 (https=) | 2023-06-16 |
Family
ID=73781254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021573215A Pending JP2022536653A (ja) | 2019-06-10 | 2020-06-10 | 老化関連分泌表現型を修整する方法および組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220241229A1 (https=) |
| EP (1) | EP3980000A4 (https=) |
| JP (1) | JP2022536653A (https=) |
| CN (1) | CN114126599A (https=) |
| AU (1) | AU2020293094A1 (https=) |
| CA (1) | CA3142781A1 (https=) |
| WO (1) | WO2020252005A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102833111B1 (ko) | 2018-09-25 | 2025-07-10 | 폰세 드 리온 헬스 데지그네이티드 액티비티 컴퍼니 | 칼슘 알파-케토글루타레이트의 제조 방법 |
| DE102021111719A1 (de) * | 2021-05-05 | 2022-11-10 | Henkel Ag & Co. Kgaa | Erhalt der Haarstruktur gegenüber Umwelteinflüssen umfassend ein Phenol und multivalente Ionen |
| US20250376678A1 (en) * | 2022-04-01 | 2025-12-11 | Japanese Foundation For Cancer Research | Therapeutic agent for cancer, testing assistance method, and screening method for therapeutic agent |
| EP4561696A1 (en) * | 2022-06-30 | 2025-06-04 | Mechanobiologics, Inc. | Reversal of cellular senescence by treatment with low frequency ultrasound |
| CN115813784A (zh) * | 2022-11-28 | 2023-03-21 | 麦吉丽生物科技有限公司 | α-酮戊二酸、含有α-酮戊二酸的米发酵液在制备皮肤炎症抑制剂中的用途 |
| WO2024123738A1 (en) * | 2022-12-06 | 2024-06-13 | Ponce De Leon Health Designated Activity Company | Compositions and methods for treating diseases responsive to akg-vitamin b coadministration |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198465A (en) * | 1991-06-19 | 1993-03-30 | Dioguardi Francesco S | Compositions based on amino acids for preventing and treating precursor deficiencies in the synthesis of collagen |
| CA2447357A1 (en) * | 2001-05-22 | 2002-11-28 | Gene Logic, Inc. | Molecular toxicology modeling |
| DK1824470T3 (da) * | 2004-12-17 | 2014-08-18 | Cash Alan Brian | Fremgangsmåde til forlængelse af levetiden og forsinke starttidspunktet for alders-relateret sygdom |
| WO2007053943A1 (en) * | 2005-11-08 | 2007-05-18 | Multi Formulations Ltd. | The use of compositions comprising ketoacids and amino acids for increasing muscle mass and muscle performance |
| PL379512A1 (pl) * | 2006-04-21 | 2007-10-29 | Sgp & Sons Ab | Nowe metody i ich zastosowanie |
| MX2009013937A (es) * | 2007-07-02 | 2010-04-30 | Entress Ab | Nuevo uso de compuestos quimicos farmacologicamente activos conocidos. |
| DE102009016119A1 (de) * | 2009-04-03 | 2010-10-14 | Evonik Degussa Gmbh | Nahrungsergänzungsmittel enthaltend alpha-Ketosäuren zur Unterstützung der Diabetestherapie |
| JP2014511890A (ja) * | 2011-04-18 | 2014-05-19 | ネステク ソシエテ アノニム | α−ＨＩＣＡ及びα−ケトグルタル酸を含有する栄養組成物 |
| US20150328176A1 (en) * | 2013-01-25 | 2015-11-19 | Winning The Fight Inc. | Composition for treatment of neurodegenerative disease |
| IL286427B2 (en) * | 2014-01-28 | 2024-08-01 | Mayo Found Medical Education & Res | Inhibitors bcl-2 anti-apoptotic protein family members for treatment of non cancer pulmonary disease or an opthalmic disease |
| KR20160111529A (ko) * | 2014-02-12 | 2016-09-26 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 노화 및 연령 관련 질환 및 증상의 치료를 위한 조성물 및 방법 |
| CN106963749A (zh) * | 2017-03-23 | 2017-07-21 | 华南农业大学 | α‑酮戊二酸（盐）在抗疲劳和提高肌肉运动力量方面的应用 |
| SG10202107237SA (en) * | 2017-04-25 | 2021-08-30 | Buck Inst Res Aging | Formulations for extending lifespan and healthspan |
| CN108774203A (zh) * | 2018-06-25 | 2018-11-09 | 北京未蓝时代科技有限公司 | 一种延缓哺乳动物细胞和机体衰老的化合物及其应用 |
| WO2020086733A1 (en) * | 2018-10-24 | 2020-04-30 | Ponce De Leon Health Designated Activity Company | Nicotinamide riboside compositions for healthspan extension |
-
2020
- 2020-06-10 CN CN202080052117.8A patent/CN114126599A/zh active Pending
- 2020-06-10 AU AU2020293094A patent/AU2020293094A1/en not_active Abandoned
- 2020-06-10 US US17/617,436 patent/US20220241229A1/en not_active Abandoned
- 2020-06-10 WO PCT/US2020/036974 patent/WO2020252005A1/en not_active Ceased
- 2020-06-10 EP EP20823672.9A patent/EP3980000A4/en not_active Withdrawn
- 2020-06-10 CA CA3142781A patent/CA3142781A1/en active Pending
- 2020-06-10 JP JP2021573215A patent/JP2022536653A/ja active Pending
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