JP2013525422A5 - - Google Patents
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- Publication number
- JP2013525422A5 JP2013525422A5 JP2013506810A JP2013506810A JP2013525422A5 JP 2013525422 A5 JP2013525422 A5 JP 2013525422A5 JP 2013506810 A JP2013506810 A JP 2013506810A JP 2013506810 A JP2013506810 A JP 2013506810A JP 2013525422 A5 JP2013525422 A5 JP 2013525422A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pharmaceutical composition
- composition according
- treatment
- biochemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 22
- 238000011282 treatment Methods 0.000 claims 12
- 206010028980 Neoplasm Diseases 0.000 claims 11
- 201000011510 cancer Diseases 0.000 claims 10
- 229940043671 antithyroid preparations Drugs 0.000 claims 8
- 239000003200 antithyroid agent Substances 0.000 claims 5
- AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical compound IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 claims 4
- 238000011394 anticancer treatment Methods 0.000 claims 4
- 230000003208 anti-thyroid effect Effects 0.000 claims 3
- 239000002552 dosage form Substances 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- 229940035722 triiodothyronine Drugs 0.000 claims 3
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims 2
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 2
- 208000032612 Glial tumor Diseases 0.000 claims 2
- 206010018338 Glioma Diseases 0.000 claims 2
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 2
- KNAHARQHSZJURB-UHFFFAOYSA-N Propylthiouracile Chemical compound CCCC1=CC(=O)NC(=S)N1 KNAHARQHSZJURB-UHFFFAOYSA-N 0.000 claims 2
- 206010070834 Sensitisation Diseases 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 201000004101 esophageal cancer Diseases 0.000 claims 2
- 229910052740 iodine Inorganic materials 0.000 claims 2
- 239000011630 iodine Substances 0.000 claims 2
- 229960002018 liothyronine sodium Drugs 0.000 claims 2
- SBXXSUDPJJJJLC-YDALLXLXSA-M liothyronine sodium Chemical compound [Na+].IC1=CC(C[C@H](N)C([O-])=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 SBXXSUDPJJJJLC-YDALLXLXSA-M 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 229960002662 propylthiouracil Drugs 0.000 claims 2
- 230000002285 radioactive effect Effects 0.000 claims 2
- 230000008313 sensitization Effects 0.000 claims 2
- 238000001356 surgical procedure Methods 0.000 claims 2
- 210000001685 thyroid gland Anatomy 0.000 claims 2
- VEEGZPWAAPPXRB-BJMVGYQFSA-N (3e)-3-(1h-imidazol-5-ylmethylidene)-1h-indol-2-one Chemical compound O=C1NC2=CC=CC=C2\C1=C/C1=CN=CN1 VEEGZPWAAPPXRB-BJMVGYQFSA-N 0.000 claims 1
- RNAMYOYQYRYFQY-UHFFFAOYSA-N 2-(4,4-difluoropiperidin-1-yl)-6-methoxy-n-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine Chemical compound N1=C(N2CCC(F)(F)CC2)N=C2C=C(OCCCN3CCCC3)C(OC)=CC2=C1NC1CCN(C(C)C)CC1 RNAMYOYQYRYFQY-UHFFFAOYSA-N 0.000 claims 1
- 208000003445 Mouth Neoplasms Diseases 0.000 claims 1
- 208000001894 Nasopharyngeal Neoplasms Diseases 0.000 claims 1
- 206010061306 Nasopharyngeal cancer Diseases 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 208000024770 Thyroid neoplasm Diseases 0.000 claims 1
- 208000008385 Urogenital Neoplasms Diseases 0.000 claims 1
- 229940121369 angiogenesis inhibitor Drugs 0.000 claims 1
- 239000004037 angiogenesis inhibitor Substances 0.000 claims 1
- 230000002491 angiogenic effect Effects 0.000 claims 1
- 238000001815 biotherapy Methods 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 238000010322 bone marrow transplantation Methods 0.000 claims 1
- 201000007455 central nervous system cancer Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- 238000002648 combination therapy Methods 0.000 claims 1
- 201000010918 connective tissue cancer Diseases 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 238000001415 gene therapy Methods 0.000 claims 1
- 208000005017 glioblastoma Diseases 0.000 claims 1
- 210000002149 gonad Anatomy 0.000 claims 1
- 230000003054 hormonal effect Effects 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000002647 laser therapy Methods 0.000 claims 1
- 208000012987 lip and oral cavity carcinoma Diseases 0.000 claims 1
- PMRYVIKBURPHAH-UHFFFAOYSA-N methimazole Chemical compound CN1C=CNC1=S PMRYVIKBURPHAH-UHFFFAOYSA-N 0.000 claims 1
- 238000002625 monoclonal antibody therapy Methods 0.000 claims 1
- 238000011275 oncology therapy Methods 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 claims 1
- 201000001219 parotid gland cancer Diseases 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
- 238000002428 photodynamic therapy Methods 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
- 238000011476 stem cell transplantation Methods 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 238000000015 thermotherapy Methods 0.000 claims 1
- 229960002178 thiamazole Drugs 0.000 claims 1
- 125000001391 thioamide group Chemical group 0.000 claims 1
- 201000002510 thyroid cancer Diseases 0.000 claims 1
- 208000037964 urogenital cancer Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32882510P | 2010-04-28 | 2010-04-28 | |
| US61/328,825 | 2010-04-28 | ||
| PCT/IL2011/000346 WO2011135574A1 (en) | 2010-04-28 | 2011-04-28 | Methods, compositions and kits for providing a therapeutic treatment |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013525422A JP2013525422A (ja) | 2013-06-20 |
| JP2013525422A5 true JP2013525422A5 (enExample) | 2014-06-19 |
| JP5921529B2 JP5921529B2 (ja) | 2016-05-24 |
Family
ID=44860959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013506810A Expired - Fee Related JP5921529B2 (ja) | 2010-04-28 | 2011-04-28 | 治療的処置を提供するための方法、組成物およびキット |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9655984B2 (enExample) |
| EP (1) | EP2563120B1 (enExample) |
| JP (1) | JP5921529B2 (enExample) |
| KR (1) | KR101841304B1 (enExample) |
| CN (1) | CN102858156B (enExample) |
| AU (1) | AU2011246851B2 (enExample) |
| BR (1) | BR112012027463A2 (enExample) |
| CA (1) | CA2797625C (enExample) |
| ES (1) | ES2791708T3 (enExample) |
| MX (1) | MX2012012479A (enExample) |
| WO (1) | WO2011135574A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX386702B (es) | 2014-02-10 | 2025-03-19 | Fred Hutchinson Cancer Center | Tratamiento con halogeno de ataque cardiaco y lesion isquemica. |
| CN105486869A (zh) * | 2014-10-08 | 2016-04-13 | 江苏维赛科技生物发展有限公司 | 一种检测动物源食品中甲巯咪唑残留的酶联免疫试剂盒及其应用 |
| US20200222348A1 (en) * | 2017-05-08 | 2020-07-16 | Musli Thyropeutics Ltd. | Bimodal modified release compositions for cancer treatment |
| WO2021257806A1 (en) * | 2020-06-18 | 2021-12-23 | Fred Hutchinson Cancer Research Center | Iodide for treatment of nonthyroidal illness syndrome |
| CN114605278A (zh) * | 2022-02-11 | 2022-06-10 | 天津市肿瘤医院（天津医科大学肿瘤医院） | T3或其可药用盐在制备脑胶质瘤放化疗药物方面的应用 |
| CN114878840A (zh) * | 2022-07-12 | 2022-08-09 | 昆明思安生物科技有限公司 | 磁微粒化学发光测定三碘甲状腺原氨酸试剂盒及检测方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB851610A (en) | 1956-03-07 | 1960-10-19 | Gunther Hillman | Method for producing iodine derivatives of thyronine |
| US4426453A (en) | 1980-09-18 | 1984-01-17 | Amersham International Limited | Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds |
| JPH07116031B2 (ja) | 1986-09-24 | 1995-12-13 | 株式会社アドバンス | 制癌剤 |
| US6017958A (en) | 1996-06-04 | 2000-01-25 | Octamer, Inc. | Method of treating malignant tumors with thyroxine analogues having no significant hormonal activity |
| AU7721500A (en) | 1999-09-29 | 2001-04-30 | Human Genome Sciences, Inc. | Colon and colon cancer associated polynucleotides and polypeptides |
| US6939863B2 (en) * | 2002-01-04 | 2005-09-06 | Wei-Jan Chen | Prevention of atherosclerosis and restenosis |
| US7074426B2 (en) * | 2002-03-27 | 2006-07-11 | Frank Kochinke | Methods and drug delivery systems for the treatment of orofacial diseases |
| JP2009507847A (ja) * | 2005-09-08 | 2009-02-26 | シャイア エルエルシー | 生体利用性を増強したｔ３及びｔ４のプロドラッグ |
-
2011
- 2011-04-28 CA CA2797625A patent/CA2797625C/en not_active Expired - Fee Related
- 2011-04-28 JP JP2013506810A patent/JP5921529B2/ja not_active Expired - Fee Related
- 2011-04-28 EP EP11774538.0A patent/EP2563120B1/en active Active
- 2011-04-28 CN CN201180020423.4A patent/CN102858156B/zh not_active Expired - Fee Related
- 2011-04-28 ES ES11774538T patent/ES2791708T3/es active Active
- 2011-04-28 MX MX2012012479A patent/MX2012012479A/es not_active Application Discontinuation
- 2011-04-28 AU AU2011246851A patent/AU2011246851B2/en not_active Ceased
- 2011-04-28 BR BR112012027463A patent/BR112012027463A2/pt not_active Application Discontinuation
- 2011-04-28 US US13/643,907 patent/US9655984B2/en not_active Expired - Fee Related
- 2011-04-28 WO PCT/IL2011/000346 patent/WO2011135574A1/en not_active Ceased
- 2011-04-28 KR KR1020127030962A patent/KR101841304B1/ko not_active Expired - Fee Related
-
2017
- 2017-04-11 US US15/484,691 patent/US10398789B2/en not_active Expired - Fee Related
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