JP2013522376A - 変性疾患を治療するための組成物および方法 - Google Patents
変性疾患を治療するための組成物および方法 Download PDFInfo
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- JP2013522376A JP2013522376A JP2013501494A JP2013501494A JP2013522376A JP 2013522376 A JP2013522376 A JP 2013522376A JP 2013501494 A JP2013501494 A JP 2013501494A JP 2013501494 A JP2013501494 A JP 2013501494A JP 2013522376 A JP2013522376 A JP 2013522376A
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US31718510P | 2010-03-24 | 2010-03-24 | |
| US61/317,185 | 2010-03-24 | ||
| PCT/US2011/029846 WO2011119869A1 (en) | 2010-03-24 | 2011-03-24 | Compositions and methods for the treatment of degenerative diseases |
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| JP2015189524A Pending JP2015232051A (ja) | 2010-03-24 | 2015-09-28 | 変性疾患を治療するための組成物および方法 |
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| JP2016156126A Pending JP2016188257A (ja) | 2010-03-24 | 2016-08-09 | 変性疾患を治療するための組成物および方法 |
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| JP2020019786A (ja) * | 2015-04-30 | 2020-02-06 | エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント | オキシンドール化合物およびその医薬組成物 |
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| WO2014059009A1 (en) | 2012-10-09 | 2014-04-17 | The Procter & Gamble Company | Method of identifying synergistic cosmetic combinations |
| JP6194003B2 (ja) | 2012-10-09 | 2017-09-06 | ザ プロクター アンド ギャンブル カンパニー | 有益剤及びこれを含む組成物の特定又は評価方法 |
| EP2935303B1 (en) | 2012-12-21 | 2021-02-17 | Janssen BioPharma, Inc. | 4'-fluoro-nucleosides, 4'-fluoro-nucleotides and analogs thereof for the treatment of hcv |
| US20140275178A1 (en) * | 2013-03-13 | 2014-09-18 | Musc Foundation For Research Development | Thiazole compounds, compositions and methods for treatment of degenerative diseases and disorders |
| US9079853B2 (en) | 2013-02-07 | 2015-07-14 | Musc Foundation For Research Development | Isatin compounds, compositions and methods for treatment of degenerative diseases and disorders |
| US8921401B2 (en) | 2013-02-07 | 2014-12-30 | Musc Foundation For Research Development | Pyrazole compounds, compositions and methods for treatment of degenerative diseases and disorders |
| CA2905202C (en) | 2013-03-14 | 2019-12-31 | Universite Laval | Use of electroretinography (erg) for the assessment of psychiatric disorders |
| CN112961149A (zh) | 2014-08-11 | 2021-06-15 | 安吉恩生物医药公司 | 细胞色素p450抑制剂及其用途 |
| CN107531631B (zh) | 2014-12-31 | 2021-09-03 | 安吉昂生物医药公司 | 用于治疗疾病的方法和药剂 |
| CN104803946A (zh) * | 2015-03-03 | 2015-07-29 | 佛山市赛维斯医药科技有限公司 | 含腈基噻唑和环戊二烯结构的ptp1b抑制剂及其用途 |
| PT3319959T (pt) | 2015-07-06 | 2021-12-06 | Alkermes Inc | Inibidores hetero-halo de histona desacetilase |
| WO2017007755A1 (en) | 2015-07-06 | 2017-01-12 | Rodin Therapeutics, Inc. | Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase |
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| JP2020019786A (ja) * | 2015-04-30 | 2020-02-06 | エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント | オキシンドール化合物およびその医薬組成物 |
| JP2021059578A (ja) * | 2015-04-30 | 2021-04-15 | エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント | オキシンドール化合物およびその医薬組成物 |
| JP7091437B2 (ja) | 2015-04-30 | 2022-06-27 | エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント | オキシンドール化合物およびその医薬組成物 |
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|---|---|
| AU2011232347A1 (en) | 2012-10-04 |
| JP2015232051A (ja) | 2015-12-24 |
| US20130137728A1 (en) | 2013-05-30 |
| US20160237074A1 (en) | 2016-08-18 |
| WO2011119869A1 (en) | 2011-09-29 |
| JP2016188257A (ja) | 2016-11-04 |
| AU2011232347B2 (en) | 2015-08-06 |
| EP2550260A1 (en) | 2013-01-30 |
| CA2794018A1 (en) | 2011-09-29 |
| CA2794018C (en) | 2016-05-10 |
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