JP2013521058A5 - - Google Patents

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Publication number
JP2013521058A5
JP2013521058A5 JP2012556176A JP2012556176A JP2013521058A5 JP 2013521058 A5 JP2013521058 A5 JP 2013521058A5 JP 2012556176 A JP2012556176 A JP 2012556176A JP 2012556176 A JP2012556176 A JP 2012556176A JP 2013521058 A5 JP2013521058 A5 JP 2013521058A5
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JP
Japan
Prior art keywords
potential
epidermal tissue
electrode
tissue
voltage generator
Prior art date
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Application number
JP2012556176A
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English (en)
Japanese (ja)
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JP5706451B2 (ja
JP2013521058A (ja
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Publication date
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Priority claimed from PCT/US2011/026701 external-priority patent/WO2011109406A1/en
Publication of JP2013521058A publication Critical patent/JP2013521058A/ja
Publication of JP2013521058A5 publication Critical patent/JP2013521058A5/ja
Application granted granted Critical
Publication of JP5706451B2 publication Critical patent/JP5706451B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2012556176A 2010-03-01 2011-03-01 耐容性で最小侵襲性の皮膚電気穿孔装置 Active JP5706451B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30942210P 2010-03-01 2010-03-01
US61/309,422 2010-03-01
PCT/US2011/026701 WO2011109406A1 (en) 2010-03-01 2011-03-01 A tolerable and minimally invasive skin electroporation device

Publications (3)

Publication Number Publication Date
JP2013521058A JP2013521058A (ja) 2013-06-10
JP2013521058A5 true JP2013521058A5 (enExample) 2014-04-17
JP5706451B2 JP5706451B2 (ja) 2015-04-22

Family

ID=44542539

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012556176A Active JP5706451B2 (ja) 2010-03-01 2011-03-01 耐容性で最小侵襲性の皮膚電気穿孔装置

Country Status (14)

Country Link
US (2) US11565107B2 (enExample)
EP (1) EP2542300B1 (enExample)
JP (1) JP5706451B2 (enExample)
KR (1) KR101872408B1 (enExample)
CN (1) CN102905755B (enExample)
AU (1) AU2011223753B2 (enExample)
CA (1) CA2789736A1 (enExample)
DK (1) DK2542300T3 (enExample)
EA (1) EA025705B1 (enExample)
ES (1) ES2594498T3 (enExample)
MX (1) MX2012009986A (enExample)
PL (1) PL2542300T3 (enExample)
PT (1) PT2542300T (enExample)
WO (1) WO2011109406A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012333211A1 (en) * 2011-06-28 2013-12-19 Inovio Pharmaceuticals, Inc. A miniminally invasive dermal electroporation device
AU2015203882C1 (en) * 2011-06-28 2017-09-21 Inovio Pharmaceuticals, Inc. A minimally invasive dermal electroporation device
US11013917B2 (en) 2013-06-21 2021-05-25 Newsouth Innovations Pty Limited Method and apparatus for close-field electroporation
CN104689478A (zh) * 2013-12-09 2015-06-10 深圳市瑞吉思科技有限公司 细胞再生仪
CN103861202B (zh) 2014-03-18 2016-06-01 苏州壹达生物科技有限公司 一种利用空心电极针电穿孔给药的装置
US11318305B2 (en) * 2015-03-31 2022-05-03 Oncosec Medical Incorporated Systems and methods for improved tissue-sensing based electroporation
ES2970438T3 (es) * 2015-12-30 2024-05-28 Inovio Pharmaceuticals Inc Dispositivo de electroporación con conjunto de agujas desmontable con sistema de bloqueo
US11390840B2 (en) * 2016-09-30 2022-07-19 University Of Florida Research Foundation, Inc. Systems and methods including porous membrane for low-voltage continuous cell electroporation
CN107890608A (zh) * 2017-12-01 2018-04-10 王嘉浩 淋巴细胞增升仪
US12508423B2 (en) 2019-02-04 2025-12-30 Rutgers, The State University Of New Jersey Device for tissue electrotransfer using a microelectrode
US11071860B2 (en) 2019-02-06 2021-07-27 Oncosec Medical Incorporated Systems and methods for detecting fault conditions in electroporation therapy
BR102019013578A2 (pt) * 2019-06-28 2021-01-05 Eqt Equipamentos E Tecnologia Ltda. Ponta aplicadora de eletroporação para procedimento de eletroquimioterapia
KR102576604B1 (ko) 2021-02-16 2023-09-08 주식회사 밀알 의료용 정밀 약물주입 및 전기천공 융합 전극
KR20220159203A (ko) 2021-05-25 2022-12-02 주식회사 밀알 의료용 정밀 약물주입 및 전기천공 융합 전극

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994287A (en) * 1974-07-01 1976-11-30 Centre De Recherche Industrielle Du Quebec Trocar
US5273525A (en) 1992-08-13 1993-12-28 Btx Inc. Injection and electroporation apparatus for drug and gene delivery
US6277116B1 (en) * 1994-05-06 2001-08-21 Vidaderm Systems and methods for shrinking collagen in the dermis
ES2200187T3 (es) * 1996-07-03 2004-03-01 Altea Therapeutics Corporation Microporacion mecanica multiple de la piel o de la mucosa.
IL132103A0 (en) 1997-04-03 2001-03-19 Eletrofect As Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle
US6261281B1 (en) 1997-04-03 2001-07-17 Electrofect As Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
DE69826124T3 (de) 1997-06-30 2007-10-11 Institut Gustave Roussy Verabreichung der nukleinsäure in den quergestreiften muskel
US6241701B1 (en) * 1997-08-01 2001-06-05 Genetronics, Inc. Apparatus for electroporation mediated delivery of drugs and genes
TW368420B (en) * 1997-11-04 1999-09-01 Genetronics Inc Apparatus and method for transdermal molecular delivery by applying sufficient amplitude of electric field to induce migration of molecules through pores in the stratum corneum
US7922709B2 (en) * 1998-07-13 2011-04-12 Genetronics, Inc. Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation
JP4499295B2 (ja) * 1999-01-28 2010-07-07 サイト パルス サイエンシズ、インコーポレイテッド 細胞内への巨大分子の送達
US6678558B1 (en) * 1999-03-25 2004-01-13 Genetronics, Inc. Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US20070016268A1 (en) 2000-01-07 2007-01-18 John Carter Percutaneous electrode array
US7245963B2 (en) * 2002-03-07 2007-07-17 Advisys, Inc. Electrode assembly for constant-current electroporation and use
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
WO2003089043A2 (en) * 2002-04-19 2003-10-30 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
US20060036210A1 (en) 2004-06-30 2006-02-16 Lei Zhang Modular electroporation device with disposable electrode and drug delivery components
US20100168501A1 (en) * 2006-10-02 2010-07-01 Daniel Rogers Burnett Method and apparatus for magnetic induction therapy
EA200870252A1 (ru) 2006-02-11 2009-02-27 Дженетроникс, Инк. Устройство и способ одноигольного электропорообразования in vivo
CN101563132A (zh) * 2006-10-17 2009-10-21 Vgx药品公司 电穿孔装置及用其进行哺乳动物细胞电穿孔的方法
US20080288019A1 (en) 2007-01-31 2008-11-20 Adam Heller Electrochemical management of pain

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