PL2542300T3 - Tolerowane i minimalnie inwazyjne urządzenie do elektroporacji skóry - Google Patents

Tolerowane i minimalnie inwazyjne urządzenie do elektroporacji skóry

Info

Publication number
PL2542300T3
PL2542300T3 PL11751208T PL11751208T PL2542300T3 PL 2542300 T3 PL2542300 T3 PL 2542300T3 PL 11751208 T PL11751208 T PL 11751208T PL 11751208 T PL11751208 T PL 11751208T PL 2542300 T3 PL2542300 T3 PL 2542300T3
Authority
PL
Poland
Prior art keywords
tolerated
minimally invasive
electroporation device
invasive skin
skin electroporation
Prior art date
Application number
PL11751208T
Other languages
English (en)
Polish (pl)
Inventor
Kate Broderick
Jay Mccoy
Stephen V Kemmerrer
Feng Lin
Rune Kjeken
Original Assignee
Inovio Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inovio Pharmaceuticals, Inc. filed Critical Inovio Pharmaceuticals, Inc.
Publication of PL2542300T3 publication Critical patent/PL2542300T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0502Skin piercing electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL11751208T 2010-03-01 2011-03-01 Tolerowane i minimalnie inwazyjne urządzenie do elektroporacji skóry PL2542300T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30942210P 2010-03-01 2010-03-01

Publications (1)

Publication Number Publication Date
PL2542300T3 true PL2542300T3 (pl) 2017-06-30

Family

ID=44542539

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11751208T PL2542300T3 (pl) 2010-03-01 2011-03-01 Tolerowane i minimalnie inwazyjne urządzenie do elektroporacji skóry

Country Status (15)

Country Link
US (2) US11565107B2 (enExample)
EP (1) EP2542300B1 (enExample)
JP (1) JP5706451B2 (enExample)
KR (1) KR101872408B1 (enExample)
CN (1) CN102905755B (enExample)
AU (1) AU2011223753B2 (enExample)
BR (1) BR112012021805A2 (enExample)
CA (1) CA2789736A1 (enExample)
DK (1) DK2542300T3 (enExample)
EA (1) EA025705B1 (enExample)
ES (1) ES2594498T3 (enExample)
MX (1) MX2012009986A (enExample)
PL (1) PL2542300T3 (enExample)
PT (1) PT2542300T (enExample)
WO (1) WO2011109406A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015203882C1 (en) * 2011-06-28 2017-09-21 Inovio Pharmaceuticals, Inc. A minimally invasive dermal electroporation device
EP3473296B1 (en) 2011-06-28 2020-08-05 Inovio Pharmaceuticals, Inc. A minimally invasive dermal electroporation device
EP3010582B1 (en) * 2013-06-21 2021-04-28 Newsouth Innovations Pty Limited Method and apparatus for close-field electroporation
CN104689478A (zh) * 2013-12-09 2015-06-10 深圳市瑞吉思科技有限公司 细胞再生仪
CN103861202B (zh) 2014-03-18 2016-06-01 苏州壹达生物科技有限公司 一种利用空心电极针电穿孔给药的装置
CN115737104A (zh) * 2015-03-31 2023-03-07 昂科赛克医疗公司 用于改进的基于组织感测的电穿孔的系统和方法
MX394498B (es) 2015-12-30 2025-03-24 Inovio Pharmaceuticals Inc Dispositivo de electroporacion con arreglo de agujas extraible con sistema de bloqueo.
WO2018064463A1 (en) * 2016-09-30 2018-04-05 University Of Florida Research Foundation, Inc. Systems and methods including porous membrane for low-voltage continuous cell electroporation
CN107890608A (zh) * 2017-12-01 2018-04-10 王嘉浩 淋巴细胞增升仪
BR112021012548A2 (pt) * 2019-02-04 2021-09-14 Rutgers, The State University Of New Jersey Dispositivo para eletrotransferência de tecido com o uso de um microelétrodo
US11071860B2 (en) 2019-02-06 2021-07-27 Oncosec Medical Incorporated Systems and methods for detecting fault conditions in electroporation therapy
BR102019013578A2 (pt) * 2019-06-28 2021-01-05 Eqt Equipamentos E Tecnologia Ltda. Ponta aplicadora de eletroporação para procedimento de eletroquimioterapia
KR102576604B1 (ko) 2021-02-16 2023-09-08 주식회사 밀알 의료용 정밀 약물주입 및 전기천공 융합 전극
KR20220159203A (ko) 2021-05-25 2022-12-02 주식회사 밀알 의료용 정밀 약물주입 및 전기천공 융합 전극

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994287A (en) * 1974-07-01 1976-11-30 Centre De Recherche Industrielle Du Quebec Trocar
US5273525A (en) 1992-08-13 1993-12-28 Btx Inc. Injection and electroporation apparatus for drug and gene delivery
US6277116B1 (en) * 1994-05-06 2001-08-21 Vidaderm Systems and methods for shrinking collagen in the dermis
CA2259437C (en) * 1996-07-03 2006-12-05 Altea Technologies, Inc. Multiple mechanical microporation of skin or mucosa
US6261281B1 (en) 1997-04-03 2001-07-17 Electrofect As Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
CN1198665C (zh) 1997-04-03 2005-04-27 依莱克脱罗弗克脱联合股份有限公司 将药物和核酸导入骨骼肌的方法
BR9810369A (pt) 1997-06-30 2000-09-05 Rhone Poulenc Rorer Sa Processo de transferência de ácido nucleico para o interior de um ou mais músculos estriados, in vivo, composição, ácido mucleico e campo elétrico, e, produto de combinação
US6241701B1 (en) * 1997-08-01 2001-06-05 Genetronics, Inc. Apparatus for electroporation mediated delivery of drugs and genes
TW368420B (en) * 1997-11-04 1999-09-01 Genetronics Inc Apparatus and method for transdermal molecular delivery by applying sufficient amplitude of electric field to induce migration of molecules through pores in the stratum corneum
US7922709B2 (en) * 1998-07-13 2011-04-12 Genetronics, Inc. Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation
CA2372409C (en) 1999-01-28 2005-03-29 Alan D. King Delivery of macromolecules into cells
US6678558B1 (en) * 1999-03-25 2004-01-13 Genetronics, Inc. Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
US7113821B1 (en) * 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US20070016268A1 (en) 2000-01-07 2007-01-18 John Carter Percutaneous electrode array
US7245963B2 (en) * 2002-03-07 2007-07-17 Advisys, Inc. Electrode assembly for constant-current electroporation and use
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
AU2003226605A1 (en) * 2002-04-19 2003-11-03 Transpharma Medical Ltd. Handheld transdermal drug delivery and analyte extraction
US20060036210A1 (en) 2004-06-30 2006-02-16 Lei Zhang Modular electroporation device with disposable electrode and drug delivery components
US20100168501A1 (en) * 2006-10-02 2010-07-01 Daniel Rogers Burnett Method and apparatus for magnetic induction therapy
AU2007215263B2 (en) * 2006-02-11 2011-07-07 Genetronics, Inc. Device and method for single-needle in vivo electroporation
CN101563132A (zh) * 2006-10-17 2009-10-21 Vgx药品公司 电穿孔装置及用其进行哺乳动物细胞电穿孔的方法
US20080288019A1 (en) * 2007-01-31 2008-11-20 Adam Heller Electrochemical management of pain

Also Published As

Publication number Publication date
JP2013521058A (ja) 2013-06-10
EP2542300A1 (en) 2013-01-09
KR20130020662A (ko) 2013-02-27
EA201201203A1 (ru) 2013-04-30
EP2542300A4 (en) 2013-11-13
HK1181339A1 (zh) 2013-11-08
US20230145532A1 (en) 2023-05-11
US20130066296A1 (en) 2013-03-14
AU2011223753B2 (en) 2014-06-26
CN102905755A (zh) 2013-01-30
US11565107B2 (en) 2023-01-31
CN102905755B (zh) 2016-03-09
EP2542300B1 (en) 2016-08-10
WO2011109406A1 (en) 2011-09-09
PT2542300T (pt) 2016-11-14
MX2012009986A (es) 2012-11-21
EA025705B1 (ru) 2017-01-30
CA2789736A1 (en) 2011-09-09
US12491361B2 (en) 2025-12-09
JP5706451B2 (ja) 2015-04-22
KR101872408B1 (ko) 2018-06-28
DK2542300T3 (en) 2016-11-28
ES2594498T3 (es) 2016-12-20
AU2011223753A1 (en) 2012-09-13
BR112012021805A2 (pt) 2016-05-17

Similar Documents

Publication Publication Date Title
PL2542300T3 (pl) Tolerowane i minimalnie inwazyjne urządzenie do elektroporacji skóry
IL276694A (en) Endoscopic devices are equipped with a balloon and their methods
EP2875843A4 (en) NOZZLE DEVICE AND MINIMALLY INVASIVE INJECTION DEVICE COMPRISING THE SAME
DK2726145T3 (da) Minimalt invasivt, dermalt elektroporationsapparat
GB201006079D0 (en) Surgical device and methods
EP2819589A4 (en) MINIMALLY INVASIVE SURGICAL PROCEDURES
PL2606120T3 (pl) Ludzkie komórki ułatwiające tolerancję i ich zastosowanie
EP2608724A4 (en) MINIMALLY INVASIVE SURGICAL TECHNIQUES
BR112014025700A2 (pt) gerador cirúrgico para dispositivos ultrasônicos e eletrocirúrgicos
BR112013018469A2 (pt) dispositivos e métodos para tratamento de tecidos
PL3593762T3 (pl) Zastawka protetyczna serca i urządzenie do wprowadzania
EP2645937A4 (en) METHODS AND DEVICES FOR USE IN METABOLIC SURGERY
LT2605789T (lt) Modifikuoti relaksino polipeptidai ir jų panaudojimas
GB201012336D0 (en) Surgical device and procedure
DK3650125T3 (da) Væskeforstøver og fremgangsmåder
PL2659004T3 (pl) Modulacja dyneiny w skórze
EP2774535A4 (en) ELECTROCARDIOGRAPH AND BIOELECTRODE PAD
EP2866702A4 (en) ACCESS SPORT FOR TRANSENDOSCOPIC AND LAPAROSCOPIC SURGERY
EP2741680A4 (en) DEVICE AND METHOD FOR MINIMALLY INVASIVE SURGICAL SEWING
DK2882290T3 (da) System til at holde liv i og transportere hudbiopsier og anvendelse deraf
HRP20171280T1 (hr) Pirazolilgvanidinski inhibitori f1f0-atpaze i njihova upotreba u terapiji
EP2478828A4 (en) ENDOSCOPE TREATMENT DEVICE AND ENDOSCOPE TREATMENT METHOD
PL2521445T3 (pl) Preparat i jego zastosowanie
GB201004924D0 (en) Medical/cosmetic device
PT2563806E (pt) Leucolectinas humanas e suas utilizações