JP2013520220A - 徐放性の液剤送達装置 - Google Patents
徐放性の液剤送達装置 Download PDFInfo
- Publication number
- JP2013520220A JP2013520220A JP2012553439A JP2012553439A JP2013520220A JP 2013520220 A JP2013520220 A JP 2013520220A JP 2012553439 A JP2012553439 A JP 2012553439A JP 2012553439 A JP2012553439 A JP 2012553439A JP 2013520220 A JP2013520220 A JP 2013520220A
- Authority
- JP
- Japan
- Prior art keywords
- delivery device
- drug delivery
- drug
- container
- insert
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
【選択図】図1A
Description
Claims (15)
- 少なくとも部分的に圧力補償された流量調節機構と一体化した薬物容器を提供する薬物送達装置であって、
前記薬物送達装置は、
(a)主としてエラストマー材料から形成される第1の部分であって、膨張可能な薬物容器を少なくとも部分的に定義するとともに開口部を有する第1の部分と、
(b)前記膨張可能な薬物容器を完成させるために前記第1の部分の開口部と協働する閉鎖部分とを含み、
前記閉鎖部分は、前記第1の部分と前記閉鎖部分の間の重なりの少なくとも1つの領域を定義するために、前記開口部から内側に第1の部分に伸張し、
前記第1の部分と前記閉鎖部分は、前記薬物容器から薬物を放出するための出口流路を定義し、前記出口流路の少なくとも一部は、前記重なり領域中の前記第1の部分と前記閉鎖部分の間を通過し、前記重なり領域は、前記薬物容器内の圧力の影響を受けるように配置されることで、容器内の圧力が変わると前記出口流路のフローインピーダンスを変え、それによって、少なくとも部分的に圧力補償された流量調節機構を提供することを特徴とする薬物送達装置。 - 前記第1の部分と前記閉鎖部分の1つには、前記重なり領域を通過する前記流路の少なくとも一部を定義するために展開された細長いチャネルが提供されることを特徴とする請求項1に記載の薬物送達装置。
- 前記第1の部分は、前記開口部から内側に伸張する可撓性を有するスリーブを含んでおり、
前記閉鎖部分は、前記重なり領域を提供するように前記可撓性を有するスリーブの内部に挿入される挿入物として与えられることを特徴とする請求項1に記載の薬物送達装置。 - 前記挿入物は、前記挿入物のまわりの前記膨張可能な薬物容器のプリテンション処理を提供するような大きさであることを特徴とする請求項3に記載の薬物送達装置。
- 前記挿入物は主として多孔性材料から形成されることを特徴とする請求項3に記載の薬物送達装置。
- 前記挿入物と前記可撓性を有するスリーブは、前記可撓性を有するスリーブと前記挿入物との間の接触の程度が前記膨張可能な薬物容器内の圧力に応じて変わるように、構成されることを特徴とする請求項5に記載の薬物送達装置。
- 前記挿入物は、細長い周辺チャネルで形成されることを特徴とする請求項3に記載の薬物送達装置。
- 前記挿入物は、主として生体再吸収可能な材料から形成されることを特徴とする請求項3に記載の薬物送達装置。
- 少なくとも前記第1の部分はシリコンから形成されることを特徴とする請求項1に記載の薬物送達装置。
- 前記第1の部分と前記閉鎖部分の少なくとも1つは、生体再吸収可能な材料から形成されることを特徴とする請求項1に記載の薬物送達装置。
- 前記第1の部分と前記閉鎖部分は、2つの別個の構成要素として形成されることを特徴とする請求項1に記載の薬物送達装置。
- 前記第1の部分と前記閉鎖部分は一体的に形成され、
薬物送達装置は、前記重なり領域を生じさせるように少なくとも1つのスリーブ状の部分を逆にすることによって組み立てられることを特徴とする請求項1に記載の薬物送達装置。 - 前記重なり領域は前記膨張可能な薬物容器の外壁の一部を形成することを特徴とする請求項1に記載の薬物送達装置。
- 前記膨張可能な薬物容器内に展開される中心コアをさらに含み、前記中心コアは、前記中心コアのまわりの前記膨張可能な薬物容器の事前の引っ張りを提供するような大きさであることを特徴とする請求項13に記載の薬物送達装置。
- 前記中心コアは、前記第1の部分と前記閉鎖部分の少なくとも1つと一体的に形成されることを特徴とする請求項14に記載の薬物送達装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/709,525 | 2010-02-22 | ||
US12/709,525 US8038650B2 (en) | 2010-02-22 | 2010-02-22 | Slow release liquid drug delivery device |
PCT/IB2011/050729 WO2011101833A2 (en) | 2010-02-22 | 2011-02-22 | Slow release liquid drug delivery device |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013520220A true JP2013520220A (ja) | 2013-06-06 |
JP5827246B2 JP5827246B2 (ja) | 2015-12-02 |
Family
ID=44477118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012553439A Active JP5827246B2 (ja) | 2010-02-22 | 2011-02-22 | 徐放性の液剤送達装置 |
Country Status (5)
Country | Link |
---|---|
US (1) | US8038650B2 (ja) |
EP (1) | EP2538992B1 (ja) |
JP (1) | JP5827246B2 (ja) |
IL (1) | IL221458A (ja) |
WO (1) | WO2011101833A2 (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2316394B1 (en) | 2001-06-12 | 2016-11-23 | The Johns Hopkins University | Reservoir device for intraocular drug delivery |
US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
KR20120017030A (ko) * | 2009-04-07 | 2012-02-27 | 코닌클리케 필립스 일렉트로닉스 엔.브이. | 무밸브 약제 전달 장치 |
EP3284494A1 (en) | 2009-07-30 | 2018-02-21 | Tandem Diabetes Care, Inc. | Portable infusion pump system |
DK2470242T3 (en) * | 2009-08-27 | 2018-03-12 | Sanofi Aventis Deutschland | DRUG CONTAINER |
US9033911B2 (en) | 2010-08-05 | 2015-05-19 | Forsight Vision4, Inc. | Injector apparatus and method for drug delivery |
SI2600812T1 (sl) | 2010-08-05 | 2021-12-31 | ForSight Vision4, Inc., | Naprava za zdravljenje očesa |
US8992503B2 (en) | 2011-03-27 | 2015-03-31 | Microsert Ltd. | Miniature implanted drug delivery devices and inserter systems for introducing such devices |
US8685106B2 (en) | 2011-11-15 | 2014-04-01 | Abraham Lin | Method of a pharmaceutical delivery system for use within a joint replacement |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
JP6385423B2 (ja) | 2013-03-28 | 2018-09-05 | フォーサイト・ビジョン フォー・インコーポレーテッド | 治療物質送達用の眼移植片 |
CN110478119B (zh) | 2014-11-10 | 2022-04-15 | 弗赛特影像4股份有限公司 | 可膨胀药物递送装置和使用方法 |
CN108430405B (zh) | 2015-11-20 | 2021-04-13 | 弗赛特影像4股份有限公司 | 用于缓释药物递送装置的多孔结构 |
BR112018070383A2 (pt) | 2016-04-05 | 2019-02-05 | Forsight Vision4 Inc | dispositivos para aplicação de fármaco oculares implantáveis |
CN112752568A (zh) * | 2018-08-15 | 2021-05-04 | 微思有限公司 | 具有用于流动路径修饰的可生物降解材料的持续释出部件及相应的药物输送装置 |
CN112569457B (zh) * | 2020-12-10 | 2024-02-13 | 北京大学第三医院(北京大学第三临床医学院) | 一种持续给药囊管系统 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11164885A (ja) * | 1997-12-03 | 1999-06-22 | Piolax Inc | 薬液持続注入器 |
WO2000064513A1 (en) * | 1999-04-23 | 2000-11-02 | Situs Corporation | Pressure responsive valve for use with an intravesical infuser |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3050066A (en) * | 1958-12-31 | 1962-08-21 | Wilbur R Koehn | Retention catheters |
US3698595A (en) * | 1969-12-22 | 1972-10-17 | Norman Gortz | Pressurized dispenser |
US3788322A (en) * | 1972-12-27 | 1974-01-29 | Alza Corp | Drug delivery device with means for maintaining device in environment of use |
US4450150A (en) | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
US4351337A (en) | 1973-05-17 | 1982-09-28 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery device, and process for preparing and using the same |
IL65024A (en) | 1976-10-27 | 1989-07-31 | Bron Dan | Intravenous infusion set |
EP0121533B1 (en) * | 1982-10-08 | 1990-02-28 | HARDCASTLE, David | Balloon catheter and process for the manufacture thereof |
US4820273A (en) | 1988-03-01 | 1989-04-11 | Eaton Corporation | Implantable medication infusion device and bolus generator therefor |
US5061242A (en) | 1989-07-18 | 1991-10-29 | Infusaid, Inc. | Adjustable implantable drug infusion system |
US5674192A (en) * | 1990-12-28 | 1997-10-07 | Boston Scientific Corporation | Drug delivery |
US5213809A (en) * | 1990-01-24 | 1993-05-25 | Alza Corporation | Delivery system comprising means for controlling internal pressure |
US5439444A (en) * | 1991-01-28 | 1995-08-08 | Corpak, Inc. | Pre-formed member for percutaneous catheter |
US5163920A (en) | 1991-01-30 | 1992-11-17 | Infusaid Inc. | Flow regulator damper element |
US5176641A (en) * | 1991-07-08 | 1993-01-05 | Infusaid, Inc. | Implantable drug infusion reservoir having fluid impelling resilient foam member |
US5328469A (en) * | 1993-03-19 | 1994-07-12 | Roger Coletti | Hybrid balloon angioplasty catheter and methods of use |
US5441485A (en) * | 1994-02-24 | 1995-08-15 | Peters; Michael J. | Bladder catheter |
US5788979A (en) * | 1994-07-22 | 1998-08-04 | Inflow Dynamics Inc. | Biodegradable coating with inhibitory properties for application to biocompatible materials |
JP3251294B2 (ja) | 1994-11-10 | 2002-01-28 | ユニヴァーシティ オブ ケンタッキー リサーチ ファウンデーション | 体内に薬剤を直接送出する、移植・補充可能な放出制御装置 |
US5725493A (en) * | 1994-12-12 | 1998-03-10 | Avery; Robert Logan | Intravitreal medicine delivery |
US6395292B2 (en) * | 1996-02-02 | 2002-05-28 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
ZA981610B (en) * | 1997-03-24 | 1999-08-26 | Alza Corp | Self adjustable exit port. |
KR100262930B1 (ko) * | 1997-06-19 | 2000-08-01 | 이영규 | 의약품주입기 |
MY125849A (en) * | 1997-07-25 | 2006-08-30 | Alza Corp | Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems |
ES2378675T3 (es) * | 1997-12-30 | 2012-04-16 | Intarcia Therapeutics, Inc | Sistema de suministro de un agente beneficioso con una membrana obturadora |
US6183461B1 (en) | 1998-03-11 | 2001-02-06 | Situs Corporation | Method for delivering a medication |
US5993414A (en) | 1998-04-23 | 1999-11-30 | Medtronic, Inc. | Implantable device |
US7108440B1 (en) * | 1999-10-08 | 2006-09-19 | The Procter & Gamble Company | Applicator for distributing a substance onto a target surface |
US6656147B1 (en) * | 2000-07-17 | 2003-12-02 | Becton, Dickinson And Company | Method and delivery device for the transdermal administration of a substance |
EP2316394B1 (en) | 2001-06-12 | 2016-11-23 | The Johns Hopkins University | Reservoir device for intraocular drug delivery |
US7261734B2 (en) * | 2002-04-23 | 2007-08-28 | Boston Scientific Scimed, Inc. | Resorption-controllable medical implants |
US20040024564A1 (en) * | 2002-07-30 | 2004-02-05 | Baize Kenneth J. | Steering position sensor assembly utilizing angular velocity sensor |
US8021334B2 (en) * | 2004-05-30 | 2011-09-20 | Nilimedix Ltd. | Drug delivery device and method |
US7367968B2 (en) * | 2003-09-05 | 2008-05-06 | Codman & Shurtleff, Inc. | Implantable pump with adjustable flow rate |
EP1745813A1 (de) * | 2005-07-22 | 2007-01-24 | RoweMed AG - Medical 4 Life | Mechanisch betriebene Flüssigkeitspumpe |
US20100090152A1 (en) * | 2005-07-22 | 2010-04-15 | Roland Wex | Valve for liquid pumps |
US7867221B2 (en) * | 2006-04-27 | 2011-01-11 | Medtronic, Inc. | Infusion device and overfill protection mechanism for use with same |
ES2394271T3 (es) * | 2008-02-11 | 2013-01-30 | Imd Tech Ltd. | Sistema para liberar un líquido hidratante sobre los labios de un sujeto |
EP2307077A4 (en) * | 2008-05-16 | 2011-10-12 | Heartland Bridge Capital Inc | DELIVERY DEVICE WITH INVERSIBLE MEMBRANE |
-
2010
- 2010-02-22 US US12/709,525 patent/US8038650B2/en active Active
-
2011
- 2011-02-22 EP EP11744348.1A patent/EP2538992B1/en active Active
- 2011-02-22 WO PCT/IB2011/050729 patent/WO2011101833A2/en active Application Filing
- 2011-02-22 JP JP2012553439A patent/JP5827246B2/ja active Active
-
2012
- 2012-08-14 IL IL221458A patent/IL221458A/en active IP Right Grant
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11164885A (ja) * | 1997-12-03 | 1999-06-22 | Piolax Inc | 薬液持続注入器 |
WO2000064513A1 (en) * | 1999-04-23 | 2000-11-02 | Situs Corporation | Pressure responsive valve for use with an intravesical infuser |
Also Published As
Publication number | Publication date |
---|---|
EP2538992A4 (en) | 2017-11-01 |
JP5827246B2 (ja) | 2015-12-02 |
IL221458A (en) | 2015-06-30 |
EP2538992A2 (en) | 2013-01-02 |
US8038650B2 (en) | 2011-10-18 |
US20110208122A1 (en) | 2011-08-25 |
IL221458A0 (en) | 2012-10-31 |
WO2011101833A3 (en) | 2011-11-24 |
EP2538992B1 (en) | 2021-04-28 |
WO2011101833A2 (en) | 2011-08-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5827246B2 (ja) | 徐放性の液剤送達装置 | |
US8821474B2 (en) | Slow release liquid drug delivery device | |
US9381299B2 (en) | Implantable drug delivery devices | |
TW508254B (en) | Implantable refillable and ported controlled release drug delivery device | |
US6638263B1 (en) | Regulation of drug delivery through flow diversion | |
US8273063B2 (en) | Implantable pump for drug delivery to treat erectile dysfunction | |
US20060041229A1 (en) | Flow restriction system and method for patient infusion device | |
KR970005840B1 (ko) | 밸룬 부착시 약액 지속 주입기 | |
CA2450771A1 (en) | Reservoir device for intraocular drug delivery | |
BG63142B1 (bg) | Транскорнеална система за освобождаване на лекарствено средство | |
IE20010459A1 (en) | Drug pump with suture loops flush to outer surface | |
CN110958893B (zh) | 药物输送装置 | |
CN108289999B (zh) | 药液注入装置 | |
US20190365566A1 (en) | Implantable drug delivery device and a system & method for deployment of such devices | |
US20070016150A1 (en) | Injection Needle Assembly Comprising an Injection Needle and a Needle Guide | |
JPH02131778A (ja) | 生体内植込薬物放出システム及び該システムによる薬物の投薬方法 | |
KR20070027675A (ko) | 약액 정량주입 밸브 | |
KR100955581B1 (ko) | 기체 압력을 이용하는 약물 주입 장치 | |
WO2000064513A1 (en) | Pressure responsive valve for use with an intravesical infuser | |
JP2001104477A (ja) | 薬液持続注入器 | |
JP2725557B2 (ja) | 薬液注入器具 | |
WO2023181996A1 (ja) | 投与装置 | |
WO2023085144A1 (ja) | 投与装置 | |
KR200250097Y1 (ko) | 의약품주입기 | |
KR100400986B1 (ko) | 의약품주입기의 공급량조절장치 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130221 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20131227 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20141027 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20141105 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20150126 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150304 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20150916 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20151015 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5827246 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |