JP2013519632A5 - - Google Patents
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- Publication number
- JP2013519632A5 JP2013519632A5 JP2012552048A JP2012552048A JP2013519632A5 JP 2013519632 A5 JP2013519632 A5 JP 2013519632A5 JP 2012552048 A JP2012552048 A JP 2012552048A JP 2012552048 A JP2012552048 A JP 2012552048A JP 2013519632 A5 JP2013519632 A5 JP 2013519632A5
- Authority
- JP
- Japan
- Prior art keywords
- zoledronic acid
- molecular complex
- water
- lysine
- api
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30211010P | 2010-02-06 | 2010-02-06 | |
| US61/302,110 | 2010-02-06 | ||
| US31287910P | 2010-03-11 | 2010-03-11 | |
| US61/312,879 | 2010-03-11 | ||
| US31850310P | 2010-03-29 | 2010-03-29 | |
| US61/318,503 | 2010-03-29 | ||
| US33304110P | 2010-05-10 | 2010-05-10 | |
| US33302810P | 2010-05-10 | 2010-05-10 | |
| US61/333,028 | 2010-05-10 | ||
| US61/333,041 | 2010-05-10 | ||
| US35954410P | 2010-06-29 | 2010-06-29 | |
| US61/359,544 | 2010-06-29 | ||
| PCT/US2010/043892 WO2011014766A2 (en) | 2009-07-31 | 2010-07-30 | Crystallization method and bioavailability |
| USPCT/US2010/043916 | 2010-07-30 | ||
| US12/847,568 | 2010-07-30 | ||
| USPCT/US2010/043892 | 2010-07-30 | ||
| PCT/US2010/043916 WO2011014781A1 (en) | 2009-07-31 | 2010-07-30 | Novel oral forms of a phosphonic acid derivative |
| US12/847,568 US8399023B2 (en) | 2009-07-31 | 2010-07-30 | Crystallization method and bioavailability |
| US37981410P | 2010-09-03 | 2010-09-03 | |
| US61/379,814 | 2010-09-03 | ||
| US45577810P | 2010-10-26 | 2010-10-26 | |
| US61/455,778 | 2010-10-26 | ||
| PCT/US2011/023427 WO2011097269A1 (en) | 2010-02-06 | 2011-02-02 | Crystallization method and bioavailability |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015156109A Division JP6190429B2 (ja) | 2010-02-06 | 2015-08-06 | 結晶化法及びバイオアベイラビリティ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013519632A JP2013519632A (ja) | 2013-05-30 |
| JP2013519632A5 true JP2013519632A5 (cg-RX-API-DMAC7.html) | 2014-03-27 |
| JP5792748B2 JP5792748B2 (ja) | 2015-10-14 |
Family
ID=44355747
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012552048A Expired - Fee Related JP5792748B2 (ja) | 2010-02-06 | 2011-02-02 | 結晶化法及びバイオアベイラビリティ |
| JP2015156109A Expired - Fee Related JP6190429B2 (ja) | 2010-02-06 | 2015-08-06 | 結晶化法及びバイオアベイラビリティ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015156109A Expired - Fee Related JP6190429B2 (ja) | 2010-02-06 | 2015-08-06 | 結晶化法及びバイオアベイラビリティ |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP2531200B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5792748B2 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2012216632B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2826548A1 (cg-RX-API-DMAC7.html) |
| CY (1) | CY1119192T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2531200T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2638072T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20171201T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE035744T2 (cg-RX-API-DMAC7.html) |
| IL (1) | IL221306A0 (cg-RX-API-DMAC7.html) |
| LT (1) | LT2531200T (cg-RX-API-DMAC7.html) |
| PL (1) | PL2531200T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2531200T (cg-RX-API-DMAC7.html) |
| SI (1) | SI2531200T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011097269A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9169279B2 (en) | 2009-07-31 | 2015-10-27 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| US8980868B2 (en) | 2009-07-31 | 2015-03-17 | Thar Pharmaceuticals, Inc. | Oral forms of a phosphonic acid derivative |
| PT2459176T (pt) | 2009-07-31 | 2017-12-11 | Gruenenthal Gmbh | Método de cristalização e biodisponibilidade |
| US20160016982A1 (en) | 2009-07-31 | 2016-01-21 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| WO2011097269A1 (en) * | 2010-02-06 | 2011-08-11 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| US9340565B2 (en) | 2010-11-24 | 2016-05-17 | Thar Pharmaceuticals, Inc. | Crystalline forms |
| CN102268023B (zh) * | 2011-08-15 | 2013-04-17 | 南京丰融化学技术有限公司 | 头孢类衍生物cxd的晶型 |
| US9999629B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10413560B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
| US11654152B2 (en) | 2012-05-14 | 2023-05-23 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating disease |
| US10413561B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
| US9956238B2 (en) | 2014-05-15 | 2018-05-01 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US20140349974A1 (en) * | 2014-08-12 | 2014-11-27 | Antecip Bioventures Ii Llc | Zoledronic acid dosage forms for the treatment of pain |
| US10493085B2 (en) | 2012-05-14 | 2019-12-03 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
| US10350227B2 (en) | 2012-05-14 | 2019-07-16 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US10463682B2 (en) | 2012-05-14 | 2019-11-05 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating low back pain |
| US10016445B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| CN104349781A (zh) * | 2012-05-14 | 2015-02-11 | 安泰赛普生物风投二代有限责任公司 | 用于减轻炎性疼痛或相关病症的包含唑来膦酸或相关化合物的组合物 |
| EP2968371A4 (en) * | 2013-03-12 | 2017-04-12 | The Board of Trustees of the Leland Stanford Junior University | Modulation of cellular dna repair activity to intercept malignancy |
| ES3042216T3 (en) * | 2013-03-15 | 2025-11-19 | Xortx Therapeutics Inc | Xanthine oxidase inhibitor formulations |
| MX2016005396A (es) * | 2013-10-25 | 2017-03-01 | Antecip Bioventures Ii Llc | Composiciones para administracion oral de acido zoledronico o compuestos relacionados para tratar enfermedades. |
| AU2016324482A1 (en) * | 2015-09-18 | 2018-03-29 | Thar Pharma, Llc | Crystallization method and bioavailability |
| WO2017208070A1 (en) | 2016-05-31 | 2017-12-07 | Grünenthal GmbH | Bisphosphonic acid and coformers with lysin, glycin, nicotinamide for treating psoriatic arthritis |
| KR102723076B1 (ko) * | 2016-12-15 | 2024-11-28 | 제이투에이치바이오텍 (주) | 3성분 코크리스탈 |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| KR20220009954A (ko) | 2019-04-17 | 2022-01-25 | 컴퍼스 패쓰파인더 리미티드 | 신경인지 장애, 만성 통증을 치료하고 염증을 감소시키는 방법 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6677320B2 (en) * | 2000-01-20 | 2004-01-13 | Hoffmann-La Roches Inc. | Parenteral bisphosphonate composition with improved local tolerance |
| CA2454200A1 (en) | 2001-07-17 | 2003-01-30 | Teva Pharmaceutical Industries Ltd. | Dosage forms for immediate gastric release of a calcium transport stimulator coupled with delayed gastric release of a bis-phosphonate |
| US20040220264A1 (en) * | 2003-03-17 | 2004-11-04 | Yu Ruey J | Bioavailability and improved delivery of acidic pharmaceutical drugs |
| DE602004019881D1 (de) * | 2003-07-03 | 2009-04-23 | Teva Pharma | Kristallformen der zoledronsäure und deren natrioumsalze, amorphes natriumzoledronat und verfahren zu deren herstellung |
| US20060068010A1 (en) | 2004-09-30 | 2006-03-30 | Stephen Turner | Method for improving the bioavailability of orally delivered therapeutics |
| JO3006B1 (ar) * | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
| WO2011097269A1 (en) * | 2010-02-06 | 2011-08-11 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| PT2459176T (pt) * | 2009-07-31 | 2017-12-11 | Gruenenthal Gmbh | Método de cristalização e biodisponibilidade |
| US8980868B2 (en) * | 2009-07-31 | 2015-03-17 | Thar Pharmaceuticals, Inc. | Oral forms of a phosphonic acid derivative |
| US9340565B2 (en) * | 2010-11-24 | 2016-05-17 | Thar Pharmaceuticals, Inc. | Crystalline forms |
| CN102070668B (zh) * | 2010-12-23 | 2013-07-24 | 蚌埠丰原医药科技发展有限公司 | 一种利用相转移催化剂制备唑来膦酸及其钠盐的方法 |
-
2011
- 2011-02-02 WO PCT/US2011/023427 patent/WO2011097269A1/en not_active Ceased
- 2011-02-02 PT PT117402842T patent/PT2531200T/pt unknown
- 2011-02-02 JP JP2012552048A patent/JP5792748B2/ja not_active Expired - Fee Related
- 2011-02-02 PL PL11740284T patent/PL2531200T3/pl unknown
- 2011-02-02 EP EP11740284.2A patent/EP2531200B1/en not_active Not-in-force
- 2011-02-02 HU HUE11740284A patent/HUE035744T2/en unknown
- 2011-02-02 DK DK11740284.2T patent/DK2531200T3/en active
- 2011-02-02 SI SI201131269T patent/SI2531200T1/sl unknown
- 2011-02-02 ES ES11740284.2T patent/ES2638072T3/es active Active
- 2011-02-02 LT LTEP11740284.2T patent/LT2531200T/lt unknown
- 2011-02-02 CA CA2826548A patent/CA2826548A1/en not_active Abandoned
- 2011-02-02 HR HRP20171201TT patent/HRP20171201T1/hr unknown
-
2012
- 2012-08-05 IL IL221306A patent/IL221306A0/en unknown
- 2012-09-04 AU AU2012216632A patent/AU2012216632B2/en not_active Ceased
-
2015
- 2015-08-06 JP JP2015156109A patent/JP6190429B2/ja not_active Expired - Fee Related
-
2016
- 2016-08-25 AU AU2016219653A patent/AU2016219653B2/en not_active Ceased
-
2017
- 2017-08-07 CY CY20171100845T patent/CY1119192T1/el unknown