JP2013518090A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013518090A5 JP2013518090A5 JP2012550512A JP2012550512A JP2013518090A5 JP 2013518090 A5 JP2013518090 A5 JP 2013518090A5 JP 2012550512 A JP2012550512 A JP 2012550512A JP 2012550512 A JP2012550512 A JP 2012550512A JP 2013518090 A5 JP2013518090 A5 JP 2013518090A5
- Authority
- JP
- Japan
- Prior art keywords
- xaa
- pyy
- group
- analog
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 206010012601 diabetes mellitus Diseases 0.000 claims 5
- 208000008589 Obesity Diseases 0.000 claims 4
- 150000001413 amino acids Chemical group 0.000 claims 4
- 235000020824 obesity Nutrition 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- 230000036528 appetite Effects 0.000 claims 2
- 235000019789 appetite Nutrition 0.000 claims 2
- 235000019577 caloric intake Nutrition 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 235000012631 food intake Nutrition 0.000 claims 2
- 230000037406 food intake Effects 0.000 claims 2
- 108020001507 fusion proteins Proteins 0.000 claims 2
- 102000037865 fusion proteins Human genes 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- 244000137850 Marrubium vulgare Species 0.000 claims 1
- 206010033307 Overweight Diseases 0.000 claims 1
- 230000010933 acylation Effects 0.000 claims 1
- 238000005917 acylation reaction Methods 0.000 claims 1
- 230000009435 amidation Effects 0.000 claims 1
- 238000007112 amidation reaction Methods 0.000 claims 1
- 230000021235 carbamoylation Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 230000013595 glycosylation Effects 0.000 claims 1
- 238000006206 glycosylation reaction Methods 0.000 claims 1
- 125000000487 histidyl group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C([H])=N1 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 230000029226 lipidation Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000006320 pegylation Effects 0.000 claims 1
- 230000026731 phosphorylation Effects 0.000 claims 1
- 238000006366 phosphorylation reaction Methods 0.000 claims 1
- 230000004962 physiological condition Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000010188 recombinant method Methods 0.000 claims 1
- 238000007363 ring formation reaction Methods 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 230000019635 sulfation Effects 0.000 claims 1
- 238000005670 sulfation reaction Methods 0.000 claims 1
- 238000010189 synthetic method Methods 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1001333.2 | 2010-01-27 | ||
| GBGB1001333.2A GB201001333D0 (en) | 2010-01-27 | 2010-01-27 | Novel compounds and their effects on feeding behaviour |
| PCT/GB2011/000110 WO2011092473A1 (en) | 2010-01-27 | 2011-01-27 | Novel compounds and their effects on feeding behaviour |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013518090A JP2013518090A (ja) | 2013-05-20 |
| JP2013518090A5 true JP2013518090A5 (enExample) | 2014-03-13 |
Family
ID=42084054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012550512A Pending JP2013518090A (ja) | 2010-01-27 | 2011-01-27 | 新規化合物及び摂食行動に対するそれらの効果 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9018160B2 (enExample) |
| EP (1) | EP2528942B1 (enExample) |
| JP (1) | JP2013518090A (enExample) |
| KR (1) | KR20120127610A (enExample) |
| CN (1) | CN102741278A (enExample) |
| AU (1) | AU2011210165B2 (enExample) |
| BR (1) | BR112012018703A2 (enExample) |
| CA (1) | CA2788013A1 (enExample) |
| GB (1) | GB201001333D0 (enExample) |
| MX (1) | MX2012008792A (enExample) |
| RU (1) | RU2012136530A (enExample) |
| SG (1) | SG182578A1 (enExample) |
| WO (1) | WO2011092473A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201101459D0 (en) | 2011-01-27 | 2011-03-16 | Imp Innovations Ltd | Novel compounds and thier effects on fedding behaviour |
| SG11201508469YA (en) * | 2013-05-02 | 2015-11-27 | Glaxosmithkline Ip Dev Ltd | Therapeutic peptides |
| WO2015177573A1 (en) * | 2014-05-23 | 2015-11-26 | Imperial Innovations Limited | Peptide yy (pyy) analogues |
| US20170137486A1 (en) | 2014-05-23 | 2017-05-18 | Imperial Innovations Limited | Peptide yy (pyy) analogues |
| US20170040801A1 (en) * | 2015-08-04 | 2017-02-09 | Goal Zero Llc | Portable solar panel system electrical control |
| JP7117779B2 (ja) | 2015-12-16 | 2022-08-15 | ダイエット４ライフ・アンパルトセルスカブ | 食品ペプチド |
| GB201720188D0 (en) | 2017-12-04 | 2018-01-17 | Imperial Innovations Ltd | Analogues of PYY |
| MX2020007410A (es) | 2018-01-23 | 2020-11-09 | Gila Therapeutics Inc | Formulaciones, composiciones y métodos farmacéuticos de péptido yy. |
| GB2573145A (en) * | 2018-04-26 | 2019-10-30 | Univ Ulster | Peptides for metabolic disease |
| GB201908426D0 (en) * | 2019-06-12 | 2019-07-24 | Imp College Innovations Ltd | Appetite suppressing compounds |
| KR20230039601A (ko) | 2020-04-17 | 2023-03-21 | 아이투오 테라퓨틱스, 인코포레이티드 | 장기간 작용하는 펩티드 티로신 티로신(pyy) 유사체 및 사용 방법 |
| CN114075265B (zh) * | 2020-08-13 | 2025-08-29 | 珠海市丽珠微球科技有限公司 | 一种多肽酪氨酸酪氨酸类似物以及包含其的缓释制剂 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| CA1257199A (en) | 1986-05-20 | 1989-07-11 | Paul Y. Wang | Preparation containing bioactive macromolecular substance for multi-months release in vivo |
| IT1243390B (it) | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
| WO1993009227A1 (en) | 1991-11-06 | 1993-05-13 | Garvan Institute Of Medical Research | Human neuropeptide y-y1 receptor |
| AU7531094A (en) | 1993-08-24 | 1995-03-21 | Novo Nordisk A/S | Protracted glp-1 |
| US5907030A (en) | 1995-01-25 | 1999-05-25 | University Of Southern California | Method and compositions for lipidization of hydrophilic molecules |
| US5962270A (en) | 1996-02-06 | 1999-10-05 | Bionebraska, Inc. | Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs |
| US6355478B1 (en) | 1996-06-17 | 2002-03-12 | Eli Lilly And Company | Rhesus monkey neuropeptide Y Y2 receptor |
| US6093692A (en) | 1997-09-25 | 2000-07-25 | The University Of Southern California | Method and compositions for lipidization of hydrophilic molecules |
| FR2774674B1 (fr) | 1998-02-10 | 2000-03-24 | Atochem Elf Sa | Procede de preparation d'une solution aqueuse de peroxyde d'hydrogene directement a partir d'hydrogene et d'oxygene et dispositif permettant sa mise en oeuvre |
| US5993414A (en) | 1998-04-23 | 1999-11-30 | Medtronic, Inc. | Implantable device |
| US6436091B1 (en) | 1999-11-16 | 2002-08-20 | Microsolutions, Inc. | Methods and implantable devices and systems for long term delivery of a pharmaceutical agent |
| US6420352B1 (en) | 2000-07-19 | 2002-07-16 | W. Roy Knowles | Hair loss prevention |
| PL205971B1 (pl) | 2001-09-24 | 2010-06-30 | Imp Innovations Ltd | Zastosowanie PYY₃-₃₆ do wytwarzania leku na ograniczanie apetytu, zmniejszenie otyłości lub do zapobiegania otyłości |
| US7186692B2 (en) | 2002-12-17 | 2007-03-06 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity |
| US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
| JP5638177B2 (ja) * | 2004-02-11 | 2014-12-10 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 膵臓ポリペプチドファミリーモチーフおよびそのモチーフを含むポリペプチド |
| US20060094652A1 (en) | 2004-02-11 | 2006-05-04 | Levy Odile E | Hybrid polypeptides with selectable properties |
| DE602005021858D1 (de) | 2004-02-11 | 2010-07-29 | Amylin Pharmaceuticals Inc | Peptide der amylin familie, verfahren zu deren herstellung und verwendung |
| AU2005224027B2 (en) | 2004-03-17 | 2011-05-26 | 7Tm Pharma A/S | Y2/Y4 selective receptor agonists for therapeutic interventions |
| PL2060266T3 (pl) | 2004-03-17 | 2012-01-31 | 7Tm Pharma As | Selektywni agoniści PP2-36 receptora Y4 do interwencji terapeutycznych |
| EA011860B1 (ru) * | 2004-03-17 | 2009-06-30 | 7ТиЭм ФАРМА А/С | Селективные агонисты рецептора y2 для терапевтического воздействия |
| CN100425282C (zh) * | 2004-03-17 | 2008-10-15 | 7Tm制药联合股份有限公司 | 用于治疗性干预的y2/y4选择性受体激动剂 |
| AU2005295043A1 (en) | 2004-10-08 | 2006-04-20 | Amylin Pharmaceuticals, Inc. | Amylin family polypeptide-6 (AFP-6) analogs and methods of making and using them |
| EP3000826A1 (en) * | 2004-12-13 | 2016-03-30 | Amylin Pharmaceuticals, LLC | Pancreatic polypeptide family motifs, polypeptides and methods comprising the same |
| GB0504857D0 (en) | 2005-03-09 | 2005-04-13 | Imp College Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| JP4629488B2 (ja) | 2005-04-28 | 2011-02-09 | 本田技研工業株式会社 | プラントを制御する制御装置 |
| KR20080033392A (ko) | 2005-07-11 | 2008-04-16 | 나스텍 파마수티컬 컴퍼니 인코포레이티드 | 펩타이드 ｙｙ의 향상된 점막 전달을 위한 제형들 |
| AU2006279680B2 (en) | 2005-08-11 | 2012-12-06 | Amylin Pharmaceuticals, Llc | Hybrid polypeptides with selectable properties |
| CN101296942A (zh) * | 2005-08-11 | 2008-10-29 | 安米林药品公司 | 具有可选择特性的杂合多肽 |
| GB0613196D0 (en) | 2006-07-03 | 2006-08-09 | Imp Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| CN101970475A (zh) | 2007-07-09 | 2011-02-09 | 帝国改革有限公司 | 人类胰多肽(hpp)类似物及其对摄食行为的作用 |
| EP2195034A2 (en) * | 2007-09-27 | 2010-06-16 | Amylin Pharmaceuticals, Inc. | Peptide-peptidase inhibitor conjugates and methods of making and using same |
| WO2009138511A1 (en) * | 2008-05-16 | 2009-11-19 | Novo Nordisk A/S | Long-acting y2 and/or y4 receptor agonists |
-
2010
- 2010-01-27 GB GBGB1001333.2A patent/GB201001333D0/en not_active Ceased
-
2011
- 2011-01-27 AU AU2011210165A patent/AU2011210165B2/en not_active Ceased
- 2011-01-27 CA CA2788013A patent/CA2788013A1/en not_active Abandoned
- 2011-01-27 WO PCT/GB2011/000110 patent/WO2011092473A1/en not_active Ceased
- 2011-01-27 CN CN2011800075873A patent/CN102741278A/zh active Pending
- 2011-01-27 JP JP2012550512A patent/JP2013518090A/ja active Pending
- 2011-01-27 EP EP11701543.8A patent/EP2528942B1/en active Active
- 2011-01-27 US US13/575,133 patent/US9018160B2/en active Active
- 2011-01-27 BR BR112012018703A patent/BR112012018703A2/pt not_active IP Right Cessation
- 2011-01-27 SG SG2012052973A patent/SG182578A1/en unknown
- 2011-01-27 RU RU2012136530/10A patent/RU2012136530A/ru not_active Application Discontinuation
- 2011-01-27 KR KR1020127021836A patent/KR20120127610A/ko not_active Withdrawn
- 2011-01-27 MX MX2012008792A patent/MX2012008792A/es not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2012136530A (ru) | Новые соединения, влияющие на пищевое поведение | |
| RU2013139651A (ru) | Новые соединения, влияющие на пищевое поведение | |
| AU2018213964B2 (en) | Novel oxyntomodulin derivatives and pharmaceutical composition for treating obesity comprising the same | |
| ES2976562T3 (es) | Derivado del glucagón | |
| JP6266811B2 (ja) | 血管新生病の免疫療法 | |
| CA2965560A1 (en) | Compositions and peptides having dual glp-1r and glp-2r agonist activity | |
| HUE029798T2 (en) | Methods of administering hypoglycemic agents | |
| BRPI0721093A2 (pt) | Compostos e seus efeitos no comportamento de alimentação | |
| CA3073011C (en) | Acylated oxyntomodulin peptide analog | |
| KR101661332B1 (ko) | 글루카곤 유사 펩타이드-1 수용체 항진제를 포함하는 근감소증 치료용 약학 조성물 | |
| TW200520770A (en) | Glp-1 pharmaceutical compositions | |
| KR20260025094A (ko) | 개선된 특성을 가진 유사체 | |
| JP2025166052A (ja) | 肥満の治療における使用のためのｉｌ－４由来ペプチド | |
| WO2015180634A1 (zh) | 用于治疗2型糖尿病的长效肠激素多肽类似物及应用 | |
| RU2297238C2 (ru) | Аддитивные цитопротекторные эффекты двух биоактивных областей гормона про-опиомеланокортина | |
| AU2018214650B2 (en) | Compounds, compositions and uses thereof for improvement of bone disorders | |
| EP4687947A1 (en) | Gip activity modulators and orthostatic intolerance | |
| JP2021525261A (ja) | 代謝疾患の治療におけるｉｇｆｂｐ−２のヘパリン結合ドメイン | |
| WO2019103660A1 (en) | Method of multiple sclerosis treatment (variants) | |
| KR20250095833A (ko) | 에페글레나타이드를 유효성분으로 포함하는 약학 조성물 및 이의 투여 요법 | |
| KR20180027924A (ko) | 글루카곤 유사 펩타이드-1(glp-1), glp-1 유래 펩타이드, 또는 glp-1 분해 억제제를 포함하는 근감소증 또는 근위축증 치료용 약학 조성물 | |
| RU2022104898A (ru) | Слитый белок fgf21 fc, слитый белок glp-1 fc и комбинированный терапевтический агент, включающий их, и их применение | |
| HK40010066B (en) | Glucagon derivative | |
| TH2101002460A (th) | โปรตีนไทโรซีน-ไทโรซีน อะนาล็อกและวิธีการใช้สิ่งเดียวกัน | |
| CA2485472A1 (en) | Gh secretagogues and uses thereof |