CA2788013A1 - Novel compounds and their effects on feeding behaviour - Google Patents

Novel compounds and their effects on feeding behaviour Download PDF

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Publication number
CA2788013A1
CA2788013A1 CA2788013A CA2788013A CA2788013A1 CA 2788013 A1 CA2788013 A1 CA 2788013A1 CA 2788013 A CA2788013 A CA 2788013A CA 2788013 A CA2788013 A CA 2788013A CA 2788013 A1 CA2788013 A1 CA 2788013A1
Authority
CA
Canada
Prior art keywords
pyy
analogue
group
subject
tyr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2788013A
Other languages
English (en)
French (fr)
Inventor
Stephen Robert Bloom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ip2ipo Innovations Ltd
Original Assignee
Imperial Innovations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Innovations Ltd filed Critical Imperial Innovations Ltd
Publication of CA2788013A1 publication Critical patent/CA2788013A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G23/00Driving gear for endless conveyors; Belt- or chain-tensioning arrangements
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57545Neuropeptide Y
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G2812/00Indexing codes relating to the kind or type of conveyors
    • B65G2812/02Belt or chain conveyors
    • B65G2812/02267Conveyors having endless traction elements
    • B65G2812/02277Common features for chain conveyors
    • B65G2812/02287Driving means
    • B65G2812/02306Driving drums
    • B65G2812/02316Driving drums with means for assuring constant linear speed of chains

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Mechanical Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2788013A 2010-01-27 2011-01-27 Novel compounds and their effects on feeding behaviour Abandoned CA2788013A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1001333.2 2010-01-27
GBGB1001333.2A GB201001333D0 (en) 2010-01-27 2010-01-27 Novel compounds and their effects on feeding behaviour
PCT/GB2011/000110 WO2011092473A1 (en) 2010-01-27 2011-01-27 Novel compounds and their effects on feeding behaviour

Publications (1)

Publication Number Publication Date
CA2788013A1 true CA2788013A1 (en) 2011-08-04

Family

ID=42084054

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2788013A Abandoned CA2788013A1 (en) 2010-01-27 2011-01-27 Novel compounds and their effects on feeding behaviour

Country Status (13)

Country Link
US (1) US9018160B2 (enExample)
EP (1) EP2528942B1 (enExample)
JP (1) JP2013518090A (enExample)
KR (1) KR20120127610A (enExample)
CN (1) CN102741278A (enExample)
AU (1) AU2011210165B2 (enExample)
BR (1) BR112012018703A2 (enExample)
CA (1) CA2788013A1 (enExample)
GB (1) GB201001333D0 (enExample)
MX (1) MX2012008792A (enExample)
RU (1) RU2012136530A (enExample)
SG (1) SG182578A1 (enExample)
WO (1) WO2011092473A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201101459D0 (en) 2011-01-27 2011-03-16 Imp Innovations Ltd Novel compounds and thier effects on fedding behaviour
CN105263957A (zh) * 2013-05-02 2016-01-20 葛兰素史克知识产权开发有限公司 治疗肽
WO2015177572A1 (en) 2014-05-23 2015-11-26 Imperial Innovations Limited Peptide yy (pyy) analogues
WO2015177573A1 (en) * 2014-05-23 2015-11-26 Imperial Innovations Limited Peptide yy (pyy) analogues
US10404205B2 (en) * 2015-08-04 2019-09-03 Goal Zero Llc Portable solar panel system
EP3390425B1 (en) 2015-12-16 2024-08-07 Diet4Life ApS Dietary peptides
GB201720188D0 (en) * 2017-12-04 2018-01-17 Imperial Innovations Ltd Analogues of PYY
CA3087733A1 (en) 2018-01-23 2019-08-01 Gila Therapeutics, Inc. Peptide yy pharmaceutical formulations, compositions, and methods
GB2573145A (en) * 2018-04-26 2019-10-30 Univ Ulster Peptides for metabolic disease
GB201908426D0 (en) 2019-06-12 2019-07-24 Imp College Innovations Ltd Appetite suppressing compounds
AU2021257477A1 (en) 2020-04-17 2022-12-08 I2O Therapeutics, Inc. Long acting peptide tyrosine tyrosine (PYY) analogs and methods of use
CN114075265B (zh) * 2020-08-13 2025-08-29 珠海市丽珠微球科技有限公司 一种多肽酪氨酸酪氨酸类似物以及包含其的缓释制剂

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US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
CA1257199A (en) 1986-05-20 1989-07-11 Paul Y. Wang Preparation containing bioactive macromolecular substance for multi-months release in vivo
IT1243390B (it) 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
WO1993009227A1 (en) 1991-11-06 1993-05-13 Garvan Institute Of Medical Research Human neuropeptide y-y1 receptor
WO1995005848A1 (en) 1993-08-24 1995-03-02 Novo Nordisk A/S Protracted glp-1
US5907030A (en) 1995-01-25 1999-05-25 University Of Southern California Method and compositions for lipidization of hydrophilic molecules
US5962270A (en) 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
US6355478B1 (en) 1996-06-17 2002-03-12 Eli Lilly And Company Rhesus monkey neuropeptide Y Y2 receptor
US6093692A (en) 1997-09-25 2000-07-25 The University Of Southern California Method and compositions for lipidization of hydrophilic molecules
FR2774674B1 (fr) 1998-02-10 2000-03-24 Atochem Elf Sa Procede de preparation d'une solution aqueuse de peroxyde d'hydrogene directement a partir d'hydrogene et d'oxygene et dispositif permettant sa mise en oeuvre
US5993414A (en) 1998-04-23 1999-11-30 Medtronic, Inc. Implantable device
US6436091B1 (en) 1999-11-16 2002-08-20 Microsolutions, Inc. Methods and implantable devices and systems for long term delivery of a pharmaceutical agent
US6420352B1 (en) 2000-07-19 2002-07-16 W. Roy Knowles Hair loss prevention
IL160983A0 (en) 2001-09-24 2004-08-31 Imp College Innovations Ltd Use of pyy for preparation of a medicament for modification of feeding behavior
US7186692B2 (en) 2002-12-17 2007-03-06 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity
EP1789440A4 (en) 2004-02-11 2008-03-12 Amylin Pharmaceuticals Inc REASONS FOR THE FAMILY OF PANCREATIC POLYPEPTIDES AND POLYPEPTIDES CONTAINING THEM
EP2422807A3 (en) 2004-02-11 2012-05-30 Amylin Pharmaceuticals Inc. Hybrid polypeptides with selectable properties
US8076288B2 (en) 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
WO2006083254A1 (en) 2004-02-11 2006-08-10 Amylin Pharmaceuticals, Inc. Amylin family peptides and methods for making and using them
EA011861B1 (ru) 2004-03-17 2009-06-30 7ТиЭм ФАРМА А/С Селективные агонисты рецепторов y2/y4 для терапевтического воздействия
CN100425282C (zh) 2004-03-17 2008-10-15 7Tm制药联合股份有限公司 用于治疗性干预的y2/y4选择性受体激动剂
WO2005089786A2 (en) 2004-03-17 2005-09-29 7Tm Pharma A/S Y4 selective receptor agonists for therapeutic interventions
MXPA06010347A (es) * 2004-03-17 2007-06-19 7Tm Pharma As Agonistas de receptor selectivo de y2 para intervenciones terapeuticas.
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JP5743371B2 (ja) * 2004-12-13 2015-07-01 アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc 膵臓ポリペプチドファミリーモチーフ、ポリペプチドおよびこれらを含む方法
GB0504857D0 (en) 2005-03-09 2005-04-13 Imp College Innovations Ltd Novel compounds and their effects on feeding behaviour
JP4629488B2 (ja) 2005-04-28 2011-02-09 本田技研工業株式会社 プラントを制御する制御装置
US20090054326A1 (en) 2005-07-11 2009-02-26 Nastech Pharmaceutical Company Inc. Formulations for enhanced mucosal delivery of pyy
KR101399178B1 (ko) * 2005-08-11 2014-06-18 아스트라제네카 파마수티컬스 엘피 선별가능한 특성을 갖는 하이브리드 폴리펩티드
CA2617649A1 (en) * 2005-08-11 2007-02-22 Amylin Pharmaceuticals, Inc. Hybrid polypeptides with selectable properties
GB0613196D0 (en) 2006-07-03 2006-08-09 Imp Innovations Ltd Novel compounds and their effects on feeding behaviour
RU2506273C2 (ru) 2007-07-09 2014-02-10 Импиэриэл Инноувейшнс Лимитид Аналог панкреатического полипептида человека (варианты), фармацевтическая композиция на его основе, способ лечения ожирения или диабета, способ снижения аппетита, уменьшения поглощения пищи или снижения потребления калорий и способ косметического снижения массы посредством указанного аналога
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Also Published As

Publication number Publication date
EP2528942B1 (en) 2020-06-17
MX2012008792A (es) 2012-11-29
GB201001333D0 (en) 2010-03-17
KR20120127610A (ko) 2012-11-22
US20130023464A1 (en) 2013-01-24
CN102741278A (zh) 2012-10-17
AU2011210165B2 (en) 2014-06-05
JP2013518090A (ja) 2013-05-20
AU2011210165A1 (en) 2012-08-23
BR112012018703A2 (pt) 2017-01-10
WO2011092473A1 (en) 2011-08-04
EP2528942A1 (en) 2012-12-05
US9018160B2 (en) 2015-04-28
SG182578A1 (en) 2012-08-30
RU2012136530A (ru) 2014-03-10
WO2011092473A8 (en) 2012-08-02

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20170127