JP2013518057A5 - - Google Patents
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- Publication number
- JP2013518057A5 JP2013518057A5 JP2012550189A JP2012550189A JP2013518057A5 JP 2013518057 A5 JP2013518057 A5 JP 2013518057A5 JP 2012550189 A JP2012550189 A JP 2012550189A JP 2012550189 A JP2012550189 A JP 2012550189A JP 2013518057 A5 JP2013518057 A5 JP 2013518057A5
- Authority
- JP
- Japan
- Prior art keywords
- lys
- dmt
- arg
- phe
- trp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 230000002438 mitochondrial effect Effects 0.000 claims 4
- 230000037050 permeability transition Effects 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000004792 oxidative damage Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29806210P | 2010-01-25 | 2010-01-25 | |
| US61/298,062 | 2010-01-25 | ||
| PCT/US2011/022247 WO2011091357A1 (en) | 2010-01-25 | 2011-01-24 | Aromatic-cationic peptides and uses of same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015163826A Division JP2016000750A (ja) | 2010-01-25 | 2015-08-21 | 芳香族カチオン性ペプチドおよびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013518057A JP2013518057A (ja) | 2013-05-20 |
| JP2013518057A5 true JP2013518057A5 (https=) | 2014-03-13 |
Family
ID=44307257
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012550189A Pending JP2013518057A (ja) | 2010-01-25 | 2011-01-24 | 芳香族カチオン性ペプチドおよびその使用 |
| JP2015163826A Pending JP2016000750A (ja) | 2010-01-25 | 2015-08-21 | 芳香族カチオン性ペプチドおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015163826A Pending JP2016000750A (ja) | 2010-01-25 | 2015-08-21 | 芳香族カチオン性ペプチドおよびその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US20120329730A1 (https=) |
| EP (4) | EP2733150A1 (https=) |
| JP (2) | JP2013518057A (https=) |
| CN (2) | CN104725472A (https=) |
| AU (2) | AU2011207432A1 (https=) |
| CA (2) | CA2787331A1 (https=) |
| HK (1) | HK1208686A1 (https=) |
| WO (1) | WO2011091357A1 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2964555T3 (es) * | 2009-08-24 | 2024-04-08 | Stealth Biotherapeutics Inc | Péptido para uso en la prevención o tratamiento de la degeneración macular |
| JP2013521231A (ja) * | 2010-02-26 | 2013-06-10 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション インコーポレイテッド | ミトコンドリア標的化抗酸化剤は機械的人工呼吸誘発性横隔膜機能障害および骨格筋萎縮を防止する |
| EP3375449A1 (en) | 2010-03-15 | 2018-09-19 | Stealth Peptides International, Inc. | Combination therapies using cyclosporine and aromatic cationic peptides |
| EP3290433A1 (en) * | 2010-05-03 | 2018-03-07 | Stealth Peptides International, Inc. | Aromatic-cationic peptides and uses of same |
| CN102327600A (zh) * | 2011-09-14 | 2012-01-25 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 用于预防和治疗辐射损伤的rx31肽 |
| CN106913860A (zh) | 2011-09-29 | 2017-07-04 | 梅约医学教育与研究基金会 | 芳族阳离子肽和使用它们的方法 |
| EP2788013A4 (en) * | 2011-12-09 | 2015-08-19 | Stealth Peptides Int Inc | AROMATIC-CATIONIC PEPTIDES AND USES THEREOF |
| CN104271146A (zh) * | 2012-03-30 | 2015-01-07 | 康肽德生物医药技术有限公司 | 用于预防和治疗神经病的方法和组合物 |
| CN105753939A (zh) * | 2012-04-12 | 2016-07-13 | 康德生物医疗技术公司 | 芳香族阳离子肽及其用途 |
| EP4091624A1 (en) | 2013-03-15 | 2022-11-23 | Protagonist Therapeutics, Inc. | Hepcidin analogues and uses thereof |
| US20140294902A1 (en) * | 2013-04-02 | 2014-10-02 | Protagonist Therapeutics, Inc. | Novel a4b7 peptide antagonists |
| WO2014210056A1 (en) * | 2013-06-27 | 2014-12-31 | Stealth Peptides International, Inc. | Peptide therapeutics and methods for using same |
| CA2920735A1 (en) * | 2013-08-12 | 2015-02-19 | Stealth Biotherapeutics Corp | Combination therapy for the treatment of ischemia-reperfusion injury |
| JP2016540762A (ja) * | 2013-12-02 | 2016-12-28 | ステルス バイオセラピューティックス コープ | 白斑の治療のための組成物及び方法 |
| HRP20211448T1 (hr) | 2014-05-16 | 2021-12-24 | Protagonist Therapeutics, Inc. | Alfa4beta7 integrin tioeter peptidni antagonisti |
| CN107206254B (zh) | 2014-07-17 | 2021-08-24 | 领导医疗有限公司 | 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途 |
| WO2016054411A1 (en) | 2014-10-01 | 2016-04-07 | Protagonist Therapeutics, Inc. | NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS |
| EP3265109B1 (en) | 2015-03-06 | 2020-10-21 | Stealth BioTherapeutics Corp | Processes for preparing pharmaceutically relevant peptides |
| US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| JP6533723B2 (ja) * | 2015-09-11 | 2019-06-19 | キユーピー株式会社 | 抗酸化剤 |
| CA3006698A1 (en) * | 2015-11-30 | 2017-06-08 | Peter Schiller | Aromatic-cationic peptides conjugated to antioxidants and their use in treating complex regional pain syndrome |
| US20190002503A1 (en) | 2015-12-30 | 2019-01-03 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| CN109069572A (zh) | 2015-12-31 | 2018-12-21 | 康德生物医疗技术公司 | 包含肽的治疗性组合物和其用途 |
| CA3017359A1 (en) | 2016-03-11 | 2017-09-14 | Scott M. Duncan | Crystalline salt forms |
| WO2017180535A1 (en) | 2016-04-11 | 2017-10-19 | Carnot, Llc | Chiral peptides |
| US11034724B2 (en) | 2017-04-05 | 2021-06-15 | Stealth Biotherapeutics Corp. | Crystalline salt forms of Boc-D-Arg-DMT-Lys-(Boc)-Phe-NH2 |
| EP3681900A4 (en) * | 2017-09-11 | 2021-09-08 | Protagonist Therapeutics, Inc. | OPIOID AGONIST PEPTIDES AND THEIR USES |
| CA3089868A1 (en) | 2018-02-08 | 2019-08-15 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| WO2020014646A1 (en) | 2018-07-12 | 2020-01-16 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| US12252554B2 (en) | 2018-12-18 | 2025-03-18 | Stealth Biotherapeutics Inc. | Analogs that target mitochondrial diseases |
| JP7534382B2 (ja) | 2019-07-10 | 2024-08-14 | プロタゴニスト セラピューティクス， インコーポレイテッド | インターロイキン－２３受容体のペプチド阻害剤及び炎症性疾患を治療するためのその使用 |
| AU2021209086A1 (en) | 2020-01-15 | 2022-08-04 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| CA3167751A1 (en) | 2020-01-15 | 2021-07-22 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| JP7397239B2 (ja) | 2020-11-20 | 2023-12-12 | ヤンセン ファーマシューティカ エヌ．ベー． | インターロイキン－２３受容体のペプチド阻害剤の組成物 |
| CN117881411A (zh) | 2021-06-01 | 2024-04-12 | 艾迪雅生物有限责任公司 | 用于眼部药物的延长释放药物递送系统和使用方法 |
| EP4370146A4 (en) | 2021-07-14 | 2025-05-21 | Janssen Biotech, Inc. | Lipidated peptide inhibitors of the interleukin-23 receptor |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| EP0273696A2 (en) * | 1987-01-02 | 1988-07-06 | Merck & Co. Inc. | Renin inhibitors containing histidine replacements |
| IE903958A1 (en) * | 1989-11-06 | 1991-05-08 | Erba Carlo Spa | Reduced irreversible bombesin antagonists |
| JPH06509075A (ja) * | 1991-07-01 | 1994-10-13 | ユニヴァーシティ テクノロジーズ インターナショナル インコーポレイテッド | ＧｎＲＨ及び他の生物学的に活性なリガンドの非感度低下性類縁体 |
| US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| US5716644A (en) | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5674534A (en) | 1992-06-11 | 1997-10-07 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
| EP1599216B9 (en) * | 2003-02-04 | 2015-02-11 | Cornell Research Foundation, Inc. | Methods for preventing mitochondrial permeability transition |
| CA3024434A1 (en) * | 2004-01-23 | 2005-08-11 | Cornell Research Foundation, Inc. | Methods for reducing oxidative damage |
| EP2712620A1 (en) * | 2008-02-07 | 2014-04-02 | Cornell University | Methods for Preventing or Treating Insulin Resistance |
| EP3741381B1 (en) * | 2008-02-26 | 2024-04-24 | Cornell University | A peptide for use for prevention and treatment of acute renal injury |
-
2011
- 2011-01-24 CA CA2787331A patent/CA2787331A1/en not_active Abandoned
- 2011-01-24 US US13/519,083 patent/US20120329730A1/en not_active Abandoned
- 2011-01-24 JP JP2012550189A patent/JP2013518057A/ja active Pending
- 2011-01-24 CN CN201510081030.4A patent/CN104725472A/zh active Pending
- 2011-01-24 EP EP14155476.6A patent/EP2733150A1/en not_active Withdrawn
- 2011-01-24 CA CA3008993A patent/CA3008993A1/en not_active Abandoned
- 2011-01-24 EP EP14194189.8A patent/EP2848628A1/en not_active Withdrawn
- 2011-01-24 CN CN2011800071355A patent/CN102834408A/zh active Pending
- 2011-01-24 EP EP11735303.7A patent/EP2528934A4/en not_active Withdrawn
- 2011-01-24 WO PCT/US2011/022247 patent/WO2011091357A1/en not_active Ceased
- 2011-01-24 EP EP15185546.7A patent/EP3018138A1/en not_active Withdrawn
- 2011-01-24 AU AU2011207432A patent/AU2011207432A1/en not_active Abandoned
-
2013
- 2013-08-07 US US13/961,313 patent/US20130316964A1/en not_active Abandoned
-
2014
- 2014-09-16 US US14/488,007 patent/US20150005242A1/en not_active Abandoned
-
2015
- 2015-08-21 JP JP2015163826A patent/JP2016000750A/ja active Pending
- 2015-09-23 HK HK15109345.6A patent/HK1208686A1/xx unknown
-
2016
- 2016-02-05 AU AU2016200747A patent/AU2016200747A1/en not_active Abandoned
- 2016-02-11 US US15/041,235 patent/US20170008925A1/en not_active Abandoned
-
2017
- 2017-10-11 US US15/729,838 patent/US20180244721A1/en not_active Abandoned
-
2018
- 2018-11-30 US US16/206,777 patent/US20190330272A1/en not_active Abandoned
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