JP2013516984A - 試料中の異常核酸の増幅を確実にするための方法 - Google Patents

試料中の異常核酸の増幅を確実にするための方法 Download PDF

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Publication number
JP2013516984A
JP2013516984A JP2012548931A JP2012548931A JP2013516984A JP 2013516984 A JP2013516984 A JP 2013516984A JP 2012548931 A JP2012548931 A JP 2012548931A JP 2012548931 A JP2012548931 A JP 2012548931A JP 2013516984 A JP2013516984 A JP 2013516984A
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nucleic acid
sample
abnormal
amplification
amount
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JP2013516984A5 (https=
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アンソニー ピー. シュバー,
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プレディクティブ バイオサイエンシーズ, インコーポレイテッド
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Publication of JP2013516984A publication Critical patent/JP2013516984A/ja
Publication of JP2013516984A5 publication Critical patent/JP2013516984A5/ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2012548931A 2010-01-19 2010-09-24 試料中の異常核酸の増幅を確実にするための方法 Pending JP2013516984A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/689,597 2010-01-19
US12/689,597 US20110177512A1 (en) 2010-01-19 2010-01-19 Method for assuring amplification of an abnormal nucleic acid in a sample
PCT/US2010/050195 WO2011090517A1 (en) 2010-01-19 2010-09-24 Method for assuring amplification of an abnormal nucleic acid in a sample

Publications (2)

Publication Number Publication Date
JP2013516984A true JP2013516984A (ja) 2013-05-16
JP2013516984A5 JP2013516984A5 (https=) 2013-11-07

Family

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Family Applications (1)

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JP2012548931A Pending JP2013516984A (ja) 2010-01-19 2010-09-24 試料中の異常核酸の増幅を確実にするための方法

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Country Link
US (1) US20110177512A1 (https=)
EP (1) EP2526202A4 (https=)
JP (1) JP2013516984A (https=)
WO (1) WO2011090517A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016540508A (ja) * 2013-12-02 2016-12-28 バイオカーティス エヌ ヴイ 循環核酸の抽出

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EP1712639B1 (en) 2005-04-06 2008-08-27 Maurice Stroun Method for the diagnosis of cancer by detecting circulating DNA and RNA
US11913065B2 (en) 2012-09-04 2024-02-27 Guardent Health, Inc. Systems and methods to detect rare mutations and copy number variation
GB2533006B (en) 2012-09-04 2017-06-07 Guardant Health Inc Systems and methods to detect copy number variation
US20160040229A1 (en) 2013-08-16 2016-02-11 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
US10876152B2 (en) 2012-09-04 2020-12-29 Guardant Health, Inc. Systems and methods to detect rare mutations and copy number variation
ES2660989T3 (es) 2013-12-28 2018-03-27 Guardant Health, Inc. Métodos y sistemas para detectar variantes genéticas
WO2017106768A1 (en) 2015-12-17 2017-06-22 Guardant Health, Inc. Methods to determine tumor gene copy number by analysis of cell-free dna

Citations (2)

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US5952170A (en) * 1993-12-16 1999-09-14 Stroun; Maurice Method for diagnosing cancers
US20090234621A1 (en) * 2004-12-03 2009-09-17 Forensic Science Service Limited Method of optimizing parameters in the entire process of analysing a dna containing sample and method of modeling said process

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US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5994056A (en) * 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
US5567583A (en) * 1991-12-16 1996-10-22 Biotronics Corporation Methods for reducing non-specific priming in DNA detection
US5348853A (en) * 1991-12-16 1994-09-20 Biotronics Corporation Method for reducing non-specific priming in DNA amplification
US6033854A (en) * 1991-12-16 2000-03-07 Biotronics Corporation Quantitative PCR using blocking oligonucleotides
US5670325A (en) * 1996-08-14 1997-09-23 Exact Laboratories, Inc. Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample
EP1033411B1 (en) * 1996-06-04 2006-02-22 University of Utah Research Foundation Fluorescent donor-acceptor pair
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6100029A (en) * 1996-08-14 2000-08-08 Exact Laboratories, Inc. Methods for the detection of chromosomal aberrations
US5928870A (en) * 1997-06-16 1999-07-27 Exact Laboratories, Inc. Methods for the detection of loss of heterozygosity
US6203993B1 (en) * 1996-08-14 2001-03-20 Exact Science Corp. Methods for the detection of nucleic acids
US5989823A (en) * 1998-09-18 1999-11-23 Nexstar Pharmaceuticals, Inc. Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
GB9812768D0 (en) * 1998-06-13 1998-08-12 Zeneca Ltd Methods
DE19935772C2 (de) * 1999-07-26 2002-11-07 Epigenomics Ag Verfahren zur relativen Quantifizierung der Methylierung von Cytosin Basen in DNA-Proben
WO2008103770A2 (en) * 2007-02-20 2008-08-28 Applera Corporation Multiplex compositions and methods for quantification of human nuclear dna and human male dna and detection of pcr inhibitors
JP2010528585A (ja) * 2007-02-26 2010-08-26 ジョン ウェイン キャンサー インスティテュート 癌の診断および治療におけるb−rafdna変異の有用性
US20090203015A1 (en) * 2008-02-13 2009-08-13 Celera Corporation Multiplex assays for hormonal and growth factor receptors, and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952170A (en) * 1993-12-16 1999-09-14 Stroun; Maurice Method for diagnosing cancers
US20090234621A1 (en) * 2004-12-03 2009-09-17 Forensic Science Service Limited Method of optimizing parameters in the entire process of analysing a dna containing sample and method of modeling said process

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016540508A (ja) * 2013-12-02 2016-12-28 バイオカーティス エヌ ヴイ 循環核酸の抽出
US10385330B2 (en) 2013-12-02 2019-08-20 Biocartis N.V. Extraction of circulating nucleic acids

Also Published As

Publication number Publication date
WO2011090517A1 (en) 2011-07-28
EP2526202A1 (en) 2012-11-28
EP2526202A4 (en) 2013-07-31
US20110177512A1 (en) 2011-07-21

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