JP2013513659A - 腫瘍治療における有効なツールとしての腫瘍血管をターゲティングする新規なワクチン - Google Patents

腫瘍治療における有効なツールとしての腫瘍血管をターゲティングする新規なワクチン Download PDF

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JP2013513659A
JP2013513659A JP2012544429A JP2012544429A JP2013513659A JP 2013513659 A JP2013513659 A JP 2013513659A JP 2012544429 A JP2012544429 A JP 2012544429A JP 2012544429 A JP2012544429 A JP 2012544429A JP 2013513659 A JP2013513659 A JP 2013513659A
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vaccine
edb
tumor
medical
endosialin
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Japanese (ja)
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オルソン、アナカリン
ヘルマン、ラース
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Theravac Pharmaceuticals AB
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Theravac Pharmaceuticals AB
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4721Lipocortins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056Lectin superfamily, e.g. CD23, CD72
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2012544429A 2009-12-15 2010-12-15 腫瘍治療における有効なツールとしての腫瘍血管をターゲティングする新規なワクチン Pending JP2013513659A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0901565-2 2009-12-15
SE0901565A SE535982C2 (sv) 2009-12-15 2009-12-15 Ett nytt vaccin som angriper tumörkärl som ett effektivt redskap i tumörterapi
PCT/SE2010/000300 WO2011075035A1 (en) 2009-12-15 2010-12-15 A novel vaccine that targets tumor vessels as an efficient tool in tumor therapy

Publications (1)

Publication Number Publication Date
JP2013513659A true JP2013513659A (ja) 2013-04-22

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ID=44167552

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012544429A Pending JP2013513659A (ja) 2009-12-15 2010-12-15 腫瘍治療における有効なツールとしての腫瘍血管をターゲティングする新規なワクチン

Country Status (10)

Country Link
US (1) US20130122028A1 (de)
EP (1) EP2512510A4 (de)
JP (1) JP2013513659A (de)
CN (1) CN102791290A (de)
AU (1) AU2010332327A1 (de)
CA (1) CA2783969A1 (de)
IN (1) IN2012DN05163A (de)
RU (1) RU2012124261A (de)
SE (1) SE535982C2 (de)
WO (1) WO2011075035A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104277102B (zh) * 2014-06-27 2017-04-12 李光辉 一种检测乳腺癌标志物Annexin A1抗原表位氨基酸序列及应用
CN107903307B (zh) * 2017-10-17 2020-12-18 北京大学 一种高亲和力edb-fn蛋白靶向肽及其应用

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09505031A (ja) * 1993-08-26 1997-05-20 モーリトセン・アンド・エルスナー・エー/エス 外来t−細胞エピトープを補助として用いた、自己タンパク質に対する抗体応答の誘発
JP2005509404A (ja) * 2001-04-06 2005-04-14 マンカインド コーポレイション エピトープ配列
JP2006524485A (ja) * 2002-11-20 2006-11-02 キャンサー・リサーチ・テクノロジー・リミテッド 抗体、ポリペプチドおよびその使用
US20060286074A1 (en) * 2005-05-31 2006-12-21 Yucheng Tang Methods for immunotherapy of cancer
JP2008526760A (ja) * 2004-12-29 2008-07-24 マンカインド コーポレイション 種々の腫瘍関連抗原を含む組成物の抗癌ワクチンとしての使用
JP2008539188A (ja) * 2005-04-29 2008-11-13 バイオインヴェント インターナショナル アーベー ポリペプチド、ワクチンおよびその使用
JP2008543301A (ja) * 2005-06-13 2008-12-04 プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダ フィブロネクチンのedaドメインの使用を基にした剤および方法
JP2009518287A (ja) * 2005-11-02 2009-05-07 デューク ユニバーシティー 同時の化学療法及び免疫療法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017604A1 (en) * 1991-03-26 1992-10-15 Otsuka Pharmaceutical Factory, Inc. Anti-eda monoclonal antibody
US5342757A (en) * 1992-11-13 1994-08-30 Ludwig Institute For Cancer Research Monoclonal antibodies which specifically binds to endosialin, a 165 Kd glycoprotein found on tumor vascular endothelium, and uses thereof
EP1752160A3 (de) * 2001-04-06 2007-05-30 Mannkind Corporation Epitop-Sequenzen
TWI445525B (zh) * 2004-06-02 2014-07-21 Sidney Kimmel Cancer Ct 用以偵測、成像和治療瘤新生或血管新生的血管標的物之用途
ES2536465T3 (es) * 2008-10-01 2015-05-25 Immatics Biotechnologies Gmbh Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09505031A (ja) * 1993-08-26 1997-05-20 モーリトセン・アンド・エルスナー・エー/エス 外来t−細胞エピトープを補助として用いた、自己タンパク質に対する抗体応答の誘発
JP2005509404A (ja) * 2001-04-06 2005-04-14 マンカインド コーポレイション エピトープ配列
JP2006524485A (ja) * 2002-11-20 2006-11-02 キャンサー・リサーチ・テクノロジー・リミテッド 抗体、ポリペプチドおよびその使用
JP2008526760A (ja) * 2004-12-29 2008-07-24 マンカインド コーポレイション 種々の腫瘍関連抗原を含む組成物の抗癌ワクチンとしての使用
JP2008539188A (ja) * 2005-04-29 2008-11-13 バイオインヴェント インターナショナル アーベー ポリペプチド、ワクチンおよびその使用
US20060286074A1 (en) * 2005-05-31 2006-12-21 Yucheng Tang Methods for immunotherapy of cancer
JP2008543301A (ja) * 2005-06-13 2008-12-04 プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダ フィブロネクチンのedaドメインの使用を基にした剤および方法
JP2009518287A (ja) * 2005-11-02 2009-05-07 デューク ユニバーシティー 同時の化学療法及び免疫療法

Also Published As

Publication number Publication date
SE535982C2 (sv) 2013-03-19
WO2011075035A1 (en) 2011-06-23
RU2012124261A (ru) 2014-01-27
SE0901565A1 (sv) 2011-06-16
AU2010332327A2 (en) 2012-07-12
EP2512510A4 (de) 2014-02-26
CN102791290A (zh) 2012-11-21
US20130122028A1 (en) 2013-05-16
EP2512510A1 (de) 2012-10-24
IN2012DN05163A (de) 2015-10-23
AU2010332327A1 (en) 2012-07-05
CA2783969A1 (en) 2011-06-23

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