JP2013512910A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013512910A5 JP2013512910A5 JP2012542143A JP2012542143A JP2013512910A5 JP 2013512910 A5 JP2013512910 A5 JP 2013512910A5 JP 2012542143 A JP2012542143 A JP 2012542143A JP 2012542143 A JP2012542143 A JP 2012542143A JP 2013512910 A5 JP2013512910 A5 JP 2013512910A5
- Authority
- JP
- Japan
- Prior art keywords
- tert
- butyl
- benzimidazol
- phenyl
- pyrimidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26656209P | 2009-12-04 | 2009-12-04 | |
| US61/266,562 | 2009-12-04 | ||
| PCT/US2010/058479 WO2011068821A1 (en) | 2009-12-04 | 2010-12-01 | Benzimidazole inhibitors of leukotriene production |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013512910A JP2013512910A (ja) | 2013-04-18 |
| JP2013512910A5 true JP2013512910A5 (https=) | 2014-01-23 |
| JP5690839B2 JP5690839B2 (ja) | 2015-03-25 |
Family
ID=43530461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012542143A Active JP5690839B2 (ja) | 2009-12-04 | 2010-12-01 | ロイコトリエン産生のベンゾイミダゾール阻害薬 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8420655B2 (https=) |
| EP (1) | EP2509975B1 (https=) |
| JP (1) | JP5690839B2 (https=) |
| AR (1) | AR079260A1 (https=) |
| TW (1) | TW201130821A (https=) |
| WO (1) | WO2011068821A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5690839B2 (ja) | 2009-12-04 | 2015-03-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン産生のベンゾイミダゾール阻害薬 |
| PT2544679T (pt) * | 2010-03-12 | 2019-07-11 | Omeros Corp | Inibidores de pde-10 e composições e métodos relacionados |
| EP2632915B1 (en) * | 2010-10-29 | 2015-08-12 | Boehringer Ingelheim International GmbH | Benzimidazole inhibitors of leukotriene production |
| JP5789888B2 (ja) | 2010-11-01 | 2015-10-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン生成のベンゾイミダゾールインヒビター |
| CN102617495A (zh) * | 2012-03-22 | 2012-08-01 | 盛世泰科生物医药技术(苏州)有限公司 | 一种2-(1-1,2,4-三氮唑)苯甲醛的制备方法 |
| EP2951170B1 (en) * | 2013-02-04 | 2018-10-24 | Janssen Pharmaceutica NV | Flap modulators |
| TWI644899B (zh) | 2013-02-04 | 2018-12-21 | 健生藥品公司 | Ｆｌａｐ調節劑 |
| CN103804312B (zh) * | 2014-02-17 | 2016-04-20 | 四川百利药业有限责任公司 | 一类氮杂环化合物及其制备方法和用途 |
| EP2949653A1 (en) | 2014-05-27 | 2015-12-02 | Banoglu, Erden | Isoxazole derivatives as leukotriene biosynthesis inhibitors |
| US9920045B2 (en) | 2015-11-04 | 2018-03-20 | Omeros Corporation | Solid state forms of a PDE10 inhibitor |
| CN108299413A (zh) * | 2018-01-22 | 2018-07-20 | 复旦大学 | 一种无金属催化制备2-(胺基苯基)苯并噁唑及其衍生物的方法 |
| FI4143183T3 (fi) | 2020-04-29 | 2026-01-07 | Gasherbrum Bio Inc | Heterosyklisiä glp-1-agonisteja |
| CN113801136B (zh) * | 2020-06-16 | 2023-04-07 | 江苏恒瑞医药股份有限公司 | 咪唑并杂芳基类衍生物、其制备方法及其在医药上的应用 |
| PE20231181A1 (es) | 2020-08-06 | 2023-08-11 | Gasherbrum Bio Inc | Agonistas del glp-1 heterociclicos |
| WO2022042691A1 (en) | 2020-08-28 | 2022-03-03 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| AU2021306414B2 (en) * | 2020-09-01 | 2026-01-29 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Fused imidazole derivative, preparation method therefor, and medical use thereof |
| EP4229050A4 (en) * | 2020-10-13 | 2024-12-11 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3505609A1 (de) | 1985-02-19 | 1986-08-21 | Merck Patent Gmbh, 6100 Darmstadt | Benzimidazolyl-pyridazinone |
| RU2236220C2 (ru) * | 1998-05-22 | 2004-09-20 | Аванир Фармасьютикэлз | Аналоги бензимидазола в качестве понижающих регуляторов ige |
| US6303645B1 (en) * | 1998-05-22 | 2001-10-16 | Avanir Pharmaceuticals | Benzimidazole derivatives as modulators of IgE |
| CZ2002356A3 (cs) | 1999-08-06 | 2002-06-12 | Janssen Pharmaceutica N. V. | Deriváty 6-azauracilu inhibující interleukin-5 |
| WO2004014905A1 (en) * | 2002-08-08 | 2004-02-19 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted benzimidazole compounds |
| CA2534649A1 (en) | 2003-08-01 | 2005-02-10 | Genelabs Technologies, Inc. | Bicyclic imidazol derivatives against flaviviridae |
| US7319108B2 (en) | 2004-01-25 | 2008-01-15 | Sanofi-Aventis Deutschland Gmbh | Aryl-substituted heterocycles, process for their preparation and their use as medicaments |
| WO2006044602A2 (en) | 2004-10-18 | 2006-04-27 | Merck & Co., Inc. | Diphenyl substituted alkanes as flap inhiibitors |
| US7405302B2 (en) * | 2005-10-11 | 2008-07-29 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
| WO2007120574A2 (en) | 2006-04-11 | 2007-10-25 | Merck & Co., Inc. | Diaryl substituted alkanes |
| US7495024B2 (en) | 2006-08-07 | 2009-02-24 | Via Pharmaceuticals, Inc. | Phenylalkyl N-hydroxyureas for combating atherosclerotic plaque |
| ATE543810T1 (de) | 2006-09-01 | 2012-02-15 | Merck Sharp & Dohme | Hemmer des 5-lipoxygenase aktivierenden proteins (flap) |
| EP2099789A4 (en) * | 2006-12-04 | 2012-02-15 | Boehringer Ingelheim Int | INHIBITORS OF HIV REPLICATION |
| WO2008071944A1 (en) * | 2006-12-14 | 2008-06-19 | Boehringer Ingelheim International Gmbh | Benzoxazoles useful in the treatment of inflammation |
| WO2008084218A1 (en) * | 2007-01-12 | 2008-07-17 | Boehringer Ingelheim International Gmbh | Benzazole derivatives for the treatment of inflammations |
| JP2010524861A (ja) | 2007-04-20 | 2010-07-22 | メルク フロスト カナダ リミテツド | ステアロイル−補酵素ａデルタ−９デサチュラーゼの阻害剤としての新規な複素環式芳香族化合物 |
| EP2546232A1 (en) | 2007-06-20 | 2013-01-16 | Merck Sharp & Dohme Corp. | Diphenyl Substituted Alkanes |
| AU2008311375A1 (en) | 2007-10-10 | 2009-04-16 | Merck Sharp & Dohme Corp. | Diphenyl substituted cycloalkanes |
| DE102009033208A1 (de) * | 2009-07-15 | 2011-01-20 | Merck Patent Gmbh | Aminopyridinderivate |
| JP5690839B2 (ja) | 2009-12-04 | 2015-03-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン産生のベンゾイミダゾール阻害薬 |
| BR112012028894A2 (pt) | 2010-05-12 | 2019-09-24 | Univ Vanderbilt | sulfona heterocíclica como potenciadores alostéricos de mglur4, composições e métodos de tratamento de disfunção neurológica |
-
2010
- 2010-12-01 JP JP2012542143A patent/JP5690839B2/ja active Active
- 2010-12-01 US US12/957,766 patent/US8420655B2/en active Active
- 2010-12-01 WO PCT/US2010/058479 patent/WO2011068821A1/en not_active Ceased
- 2010-12-01 EP EP10788191.4A patent/EP2509975B1/en active Active
- 2010-12-03 TW TW099142221A patent/TW201130821A/zh unknown
- 2010-12-03 AR ARP100104476A patent/AR079260A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013512910A5 (https=) | ||
| JP2013519680A5 (https=) | ||
| JP2009525984A5 (https=) | ||
| JP2019517455A5 (https=) | ||
| RU2352568C2 (ru) | [1,2,4]оксадиазолы (варианты), способ их получения, фармацевтическая композиция и способ ингибирования активации метаботропных глютаматных рецепторов-5 | |
| US8420655B2 (en) | Benzimidazole inhibitors of leukotriene production | |
| JP2015533157A5 (https=) | ||
| JP2014525444A5 (https=) | ||
| JP2018535999A5 (https=) | ||
| JP2009536196A5 (https=) | ||
| HRP20171454T1 (hr) | Fuzionirani heterociklični spojevi kao modulatori ionskih kanala | |
| JP2009519965A5 (https=) | ||
| JP2013514308A5 (https=) | ||
| HRP20191140T1 (hr) | Spojevi i pripravci kao inhibitori c-kit kinaze | |
| JP2007511485A5 (https=) | ||
| JP2013518046A5 (https=) | ||
| JP2015517580A5 (https=) | ||
| JP2008501673A5 (https=) | ||
| RU2012116207A (ru) | Производные индола в качестве модуляторов crac | |
| CA2656915A1 (en) | Human protein tyrosine phosphatase inhibitors and methods of use | |
| HRP20110335T1 (hr) | Supstituirani biciklolaktamski spojevi | |
| JP2007523142A5 (https=) | ||
| US9511073B2 (en) | Aromatic amides and uses thereof | |
| JPWO2020092196A5 (https=) | ||
| HRP20140893T1 (hr) | Derivati 3,4,4a,10b-tetrahidro-1h-tiopirano-[4,3-c]izokinolina |