JP2013512676A5 - - Google Patents

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Publication number
JP2013512676A5
JP2013512676A5 JP2012542230A JP2012542230A JP2013512676A5 JP 2013512676 A5 JP2013512676 A5 JP 2013512676A5 JP 2012542230 A JP2012542230 A JP 2012542230A JP 2012542230 A JP2012542230 A JP 2012542230A JP 2013512676 A5 JP2013512676 A5 JP 2013512676A5
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JP
Japan
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scf
tpo
medium
pluripotent stem
combinations
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Application number
JP2012542230A
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English (en)
Japanese (ja)
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JP2013512676A (ja
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Priority claimed from PCT/US2010/058990 external-priority patent/WO2011069127A1/en
Publication of JP2013512676A publication Critical patent/JP2013512676A/ja
Publication of JP2013512676A5 publication Critical patent/JP2013512676A5/ja
Pending legal-status Critical Current

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JP2012542230A 2009-12-04 2010-12-03 無間質条件下におけるヒト胚性幹細胞からの機能的巨核球および血小板の大規模生成 Pending JP2013512676A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26693909P 2009-12-04 2009-12-04
US61/266,939 2009-12-04
US38416510P 2010-09-17 2010-09-17
US61/384,165 2010-09-17
PCT/US2010/058990 WO2011069127A1 (en) 2009-12-04 2010-12-03 Large scale generation of functional megakaryocytes and platelets from human embryonic stem cells under stromal-free conditions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016086761A Division JP2016135138A (ja) 2009-12-04 2016-04-25 無間質条件下におけるヒト胚性幹細胞からの機能的巨核球および血小板の大規模生成

Publications (2)

Publication Number Publication Date
JP2013512676A JP2013512676A (ja) 2013-04-18
JP2013512676A5 true JP2013512676A5 (https=) 2014-01-16

Family

ID=44115332

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2012542230A Pending JP2013512676A (ja) 2009-12-04 2010-12-03 無間質条件下におけるヒト胚性幹細胞からの機能的巨核球および血小板の大規模生成
JP2016086761A Pending JP2016135138A (ja) 2009-12-04 2016-04-25 無間質条件下におけるヒト胚性幹細胞からの機能的巨核球および血小板の大規模生成
JP2019039160A Pending JP2019122385A (ja) 2009-12-04 2019-03-05 無間質条件下におけるヒト胚性幹細胞からの機能的巨核球および血小板の大規模生成
JP2022011675A Pending JP2022064953A (ja) 2009-12-04 2022-01-28 無間質条件下におけるヒト胚性幹細胞からの機能的巨核球および血小板の大規模生成

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2016086761A Pending JP2016135138A (ja) 2009-12-04 2016-04-25 無間質条件下におけるヒト胚性幹細胞からの機能的巨核球および血小板の大規模生成
JP2019039160A Pending JP2019122385A (ja) 2009-12-04 2019-03-05 無間質条件下におけるヒト胚性幹細胞からの機能的巨核球および血小板の大規模生成
JP2022011675A Pending JP2022064953A (ja) 2009-12-04 2022-01-28 無間質条件下におけるヒト胚性幹細胞からの機能的巨核球および血小板の大規模生成

Country Status (10)

Country Link
US (2) US9988603B2 (https=)
EP (1) EP2507359A4 (https=)
JP (4) JP2013512676A (https=)
KR (4) KR20180086301A (https=)
AU (4) AU2010325811A1 (https=)
BR (1) BR112012013497A2 (https=)
CA (2) CA2782013C (https=)
IN (1) IN2012DN05054A (https=)
RU (1) RU2012127810A (https=)
WO (1) WO2011069127A1 (https=)

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CN106434527A (zh) 2006-04-14 2017-02-22 安斯泰来再生医药协会 血管瘤集落形成细胞
KR20180086301A (ko) 2009-12-04 2018-07-30 스템 셀 앤드 리제너러티브 메디신 인터내셔날, 인크. 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성
SI2785359T1 (sl) 2011-11-30 2018-11-30 Astellas Institute For Regenerative Medicine Mezenhimske stromalne celice in uporabe povezane z njimi
US8961956B2 (en) 2011-11-30 2015-02-24 Ocata Therapeutics, Inc. Mesenchymal stromal cells and uses related thereto
GB201210857D0 (en) 2012-06-19 2012-08-01 Cambridge Entpr Ltd Transcription factor mediated programming towards megakaryocytes
HK1208054A1 (en) 2012-07-12 2016-02-19 爱姆斯坦生物技术公司 Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
US9074186B2 (en) 2012-08-15 2015-07-07 Boston Medical Center Corporation Production of red blood cells and platelets from stem cells
CA2896053A1 (en) 2012-12-21 2014-06-26 Ocata Therapeutics, Inc. Methods for production of platelets from pluripotent stem cells and compositions thereof
JP6580329B2 (ja) 2014-03-31 2019-09-25 シスメックス株式会社 未分化細胞から分化細胞および／または分化細胞の産生物を取得する方法
US10538738B2 (en) 2014-05-19 2020-01-21 Eleftherios Papoutsakis Megakaryocytic particles and microparticles for cell therapy and fate modification of stem and progenitor cells
US20180237797A1 (en) * 2015-03-30 2018-08-23 Jeffrey Thomas Loh Methods for in vitro production of platelets and compositions and uses thereof
CN108697641A (zh) 2015-08-18 2018-10-23 安斯泰来再生医药协会 临床制剂
JP7287634B2 (ja) * 2015-10-14 2023-06-06 株式会社メガカリオン 精製血小板の製造方法
JP2021509812A (ja) 2018-01-05 2021-04-08 プレートレット バイオジェネシス， インコーポレイテッド 巨核球を産生するための組成物および方法
EP3813853A4 (en) 2018-06-29 2022-04-06 Platelet Biogenesis, Inc. DELIVERY COMPOSITIONS AND METHODS OF USE
US20230190815A1 (en) 2020-05-11 2023-06-22 Strm.Bio Incorporated Compositions and methods related to megakaryocyte-derived extracellular vesicles
AU2022264498A1 (en) 2021-04-26 2023-09-28 Strm.Bio Incorporated Compositions and methods related to megakaryocyte-derived extracellular vesicles for fanconi anemia

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US5128259A (en) 1989-10-27 1992-07-07 Hahnemann University Factor-dependent hematopoietic cell line exhibiting epo-induced erythrocyte maturation
EP1364197B1 (en) 2001-01-29 2010-04-14 Ivan N. Rich ATP-based assay for the determination of the proliferation status of hematopoietic stem and progenitor cells
WO2002078449A2 (en) 2001-04-02 2002-10-10 Advanced Cell Technology, Inc. Method for facilitating the production of differentiated cell types and tissues from embryonic and adult pluripotent and multipotent cells
MXPA04005010A (es) 2001-11-26 2005-04-08 Advanced Cell Tech Inc METODO PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS METODOS PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS HUMANOS REPROGRAMADOS Y CELULAS DEL TALLO HUMANAS AUTOLOGAS E ISOGENICAS.
US20040052771A1 (en) 2002-07-12 2004-03-18 Lim Sai Kiang Hemangioblast progenitor cells
US20040229350A1 (en) 2003-05-12 2004-11-18 Nikolai Strelchenko Morula derived embryonic stem cells
CN1286970C (zh) 2003-12-30 2006-11-29 上海伯瑞生物技术发展有限公司 由脐血cd34+细胞体外诱导生成巨核细胞的方法
EP1735429A4 (en) 2004-03-31 2008-06-11 Newlink Genetics Corp METHOD AND COMPOSITIONS FOR OBTAINING EMBRYONAL STEM CELLS OF ABSTINENT HEMATOPOETIC STEM CELLS AND USES THEREOF
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CN106434527A (zh) * 2006-04-14 2017-02-22 安斯泰来再生医药协会 血管瘤集落形成细胞
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
US9683232B2 (en) * 2007-12-10 2017-06-20 Kyoto University Efficient method for nuclear reprogramming
CA3186451A1 (en) 2008-05-06 2009-11-12 Astellas Institute For Regenerative Medicine Hemangio colony forming cells and non-engrafting hemangio cells
US20110086424A1 (en) 2008-05-06 2011-04-14 Advanced Cell Technology, Inc. Methods for producing enucleated erythroid cells derived from pluripotent stem cells
KR20180086301A (ko) 2009-12-04 2018-07-30 스템 셀 앤드 리제너러티브 메디신 인터내셔날, 인크. 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성

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