JP2013510842A - テオブロミンとの薬物組み合わせおよび治療におけるその使用 - Google Patents

テオブロミンとの薬物組み合わせおよび治療におけるその使用 Download PDF

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Publication number
JP2013510842A
JP2013510842A JP2012538416A JP2012538416A JP2013510842A JP 2013510842 A JP2013510842 A JP 2013510842A JP 2012538416 A JP2012538416 A JP 2012538416A JP 2012538416 A JP2012538416 A JP 2012538416A JP 2013510842 A JP2013510842 A JP 2013510842A
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JP
Japan
Prior art keywords
theobromine
opiate
codeine
cough
administered
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Pending
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JP2012538416A
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English (en)
Japanese (ja)
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JP2013510842A5 (es
Inventor
ジョン ブリュー、
ロビン マーク バニスター、
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocopea Ltd
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Biocopea Ltd
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Filing date
Publication date
Application filed by Biocopea Ltd filed Critical Biocopea Ltd
Publication of JP2013510842A publication Critical patent/JP2013510842A/ja
Publication of JP2013510842A5 publication Critical patent/JP2013510842A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2012538416A 2009-11-13 2010-11-12 テオブロミンとの薬物組み合わせおよび治療におけるその使用 Pending JP2013510842A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0919893.8 2009-11-13
GBGB0919893.8A GB0919893D0 (en) 2009-11-13 2009-11-13 Drug composition and its use in therapy
PCT/GB2010/051896 WO2011058374A1 (en) 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015237086A Division JP2016041748A (ja) 2009-11-13 2015-12-04 テオブロミンとの薬物組み合わせおよび治療におけるその使用

Publications (2)

Publication Number Publication Date
JP2013510842A true JP2013510842A (ja) 2013-03-28
JP2013510842A5 JP2013510842A5 (es) 2013-12-26

Family

ID=41509327

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012538416A Pending JP2013510842A (ja) 2009-11-13 2010-11-12 テオブロミンとの薬物組み合わせおよび治療におけるその使用
JP2015237086A Pending JP2016041748A (ja) 2009-11-13 2015-12-04 テオブロミンとの薬物組み合わせおよび治療におけるその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015237086A Pending JP2016041748A (ja) 2009-11-13 2015-12-04 テオブロミンとの薬物組み合わせおよび治療におけるその使用

Country Status (18)

Country Link
EP (1) EP2498776A1 (es)
JP (2) JP2013510842A (es)
CN (1) CN102740853B (es)
AU (1) AU2010317668C1 (es)
BR (1) BR112012011224A2 (es)
CA (1) CA2780704C (es)
CO (1) CO6551745A2 (es)
EC (2) ECSP12011893A (es)
GB (1) GB0919893D0 (es)
IL (1) IL219769A0 (es)
MX (1) MX2012005538A (es)
NZ (1) NZ599957A (es)
PE (1) PE20121472A1 (es)
RU (1) RU2587329C2 (es)
SG (1) SG10201407496SA (es)
UA (1) UA105940C2 (es)
WO (1) WO2011058374A1 (es)
ZA (1) ZA201204247B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001518928A (ja) * 1997-03-26 2001-10-16 コーボニツツ,デツゾー 鎮咳薬組成物
JP2005516917A (ja) * 2001-12-12 2005-06-09 アメリカ合衆国 細胞外アデノシン阻害剤およびアデノシン受容体阻害剤を用いて免疫応答および炎症を増強するための方法
WO2006064780A1 (ja) * 2004-12-14 2006-06-22 Shionogi & Co., Ltd. 便秘治療剤
WO2008002514A2 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3850568D1 (de) * 1987-10-08 1994-08-11 Andor Bilas Stoffgemisch zur stabilisierung der stoffwechsel-lage.
EP0719156A1 (en) * 1993-09-07 1996-07-03 The Procter & Gamble Company Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive
US6608073B1 (en) * 1998-10-14 2003-08-19 New Millennium Pharmaceutical Research, Inc. Intranasal codeine for the rapid suppression of cough and rapid relief of pain
HUP9802716A3 (en) * 1998-11-25 2000-08-28 Chinoin Gyogyszer Es Vegyeszet Pharmaceutical composition of analgesic activity
WO2004075879A1 (en) * 2003-02-28 2004-09-10 Delex Therapeutics Inc. Opioid delivery system
CN1593451A (zh) * 2003-09-12 2005-03-16 杨喜鸿 促进男性勃起的外用药物
KR20080009994A (ko) * 2006-07-25 2008-01-30 안국약품 주식회사 기침 치료용 조성물

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001518928A (ja) * 1997-03-26 2001-10-16 コーボニツツ,デツゾー 鎮咳薬組成物
JP2005516917A (ja) * 2001-12-12 2005-06-09 アメリカ合衆国 細胞外アデノシン阻害剤およびアデノシン受容体阻害剤を用いて免疫応答および炎症を増強するための方法
WO2006064780A1 (ja) * 2004-12-14 2006-06-22 Shionogi & Co., Ltd. 便秘治療剤
WO2008002514A2 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6014049893; British Journal of Pharmacology 112(3), 1994, 795-800 *
JPN6014049895; FASEB Journal 18(14), 20041107, 1-16 *

Also Published As

Publication number Publication date
IL219769A0 (en) 2012-07-31
GB0919893D0 (en) 2009-12-30
WO2011058374A1 (en) 2011-05-19
CN102740853B (zh) 2015-04-08
SG10201407496SA (en) 2015-02-27
ZA201204247B (en) 2013-02-27
AU2010317668C1 (en) 2016-02-11
CA2780704C (en) 2018-07-17
CO6551745A2 (es) 2012-10-31
MX2012005538A (es) 2012-09-28
ECSP12011893A (es) 2012-10-30
JP2016041748A (ja) 2016-03-31
ECSP12011892A (es) 2012-09-28
CA2780704A1 (en) 2011-05-19
PE20121472A1 (es) 2012-11-30
AU2010317668A1 (en) 2012-06-07
AU2010317668B2 (en) 2015-01-22
BR112012011224A2 (pt) 2017-03-01
EP2498776A1 (en) 2012-09-19
NZ599957A (en) 2014-05-30
CN102740853A (zh) 2012-10-17
RU2587329C2 (ru) 2016-06-20
RU2012124063A (ru) 2013-12-20
UA105940C2 (uk) 2014-07-10

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