JP2013510841A - テオブロミンとの薬物組み合わせおよび治療におけるその使用 - Google Patents

テオブロミンとの薬物組み合わせおよび治療におけるその使用 Download PDF

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Publication number
JP2013510841A
JP2013510841A JP2012538415A JP2012538415A JP2013510841A JP 2013510841 A JP2013510841 A JP 2013510841A JP 2012538415 A JP2012538415 A JP 2012538415A JP 2012538415 A JP2012538415 A JP 2012538415A JP 2013510841 A JP2013510841 A JP 2013510841A
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JP
Japan
Prior art keywords
theobromine
cough
dextromethorphan
opiate
administered
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Pending
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JP2012538415A
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English (en)
Japanese (ja)
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JP2013510841A5 (enExample
Inventor
ジョン ブリュー、
ロビン マーク バニスター、
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Biocopea Ltd
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Biocopea Ltd
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41509324&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2013510841(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biocopea Ltd filed Critical Biocopea Ltd
Publication of JP2013510841A publication Critical patent/JP2013510841A/ja
Publication of JP2013510841A5 publication Critical patent/JP2013510841A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2012538415A 2009-11-13 2010-11-12 テオブロミンとの薬物組み合わせおよび治療におけるその使用 Pending JP2013510841A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0919889.6A GB0919889D0 (en) 2009-11-13 2009-11-13 Drug composition and its use in therapy
GB0919889.6 2009-11-13
PCT/GB2010/051895 WO2011058373A2 (en) 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016001487A Division JP6118919B2 (ja) 2009-11-13 2016-01-07 テオブロミンとの薬物組み合わせおよび治療におけるその使用

Publications (2)

Publication Number Publication Date
JP2013510841A true JP2013510841A (ja) 2013-03-28
JP2013510841A5 JP2013510841A5 (enExample) 2013-12-26

Family

ID=41509324

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012538415A Pending JP2013510841A (ja) 2009-11-13 2010-11-12 テオブロミンとの薬物組み合わせおよび治療におけるその使用
JP2016001487A Active JP6118919B2 (ja) 2009-11-13 2016-01-07 テオブロミンとの薬物組み合わせおよび治療におけるその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016001487A Active JP6118919B2 (ja) 2009-11-13 2016-01-07 テオブロミンとの薬物組み合わせおよび治療におけるその使用

Country Status (17)

Country Link
EP (1) EP2498777A2 (enExample)
JP (2) JP2013510841A (enExample)
CN (1) CN102753174A (enExample)
AU (1) AU2010317667B2 (enExample)
BR (1) BR112012011227A2 (enExample)
CA (1) CA2780703A1 (enExample)
CO (1) CO6551744A2 (enExample)
GB (1) GB0919889D0 (enExample)
IL (1) IL219768A0 (enExample)
MX (1) MX2012005532A (enExample)
NZ (1) NZ599949A (enExample)
PE (1) PE20130147A1 (enExample)
PH (1) PH12012501369A1 (enExample)
RU (1) RU2519086C2 (enExample)
UA (1) UA108993C2 (enExample)
WO (1) WO2011058373A2 (enExample)
ZA (1) ZA201204248B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy
WO2017117347A1 (en) * 2015-12-30 2017-07-06 Markovitz M D Paul Method of treating schizophrenia

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001518928A (ja) * 1997-03-26 2001-10-16 コーボニツツ,デツゾー 鎮咳薬組成物
WO2008002514A2 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834479A (en) * 1993-03-05 1998-11-10 Mayer; David J. Method and composition for alleviating pain
CA2272640C (en) * 1996-11-25 2003-07-08 The Procter & Gamble Company Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists
US20030206942A1 (en) * 1998-09-25 2003-11-06 Neema Kulkarni Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent
US6207674B1 (en) * 1999-12-22 2001-03-27 Richard A. Smith Dextromethorphan and oxidase inhibitor for weaning patients from narcotics and anti-depressants
WO2004105705A1 (en) * 2003-05-29 2004-12-09 Unilever Plc Hair treatment compositions
US20060153926A1 (en) * 2005-01-10 2006-07-13 Bascom Charles C Compositions, products and methods for controlling weight in a mammal
US20080176955A1 (en) * 2007-01-16 2008-07-24 Victory Pharma, Inc. Combined administration of benzonatate and guaifenesin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001518928A (ja) * 1997-03-26 2001-10-16 コーボニツツ,デツゾー 鎮咳薬組成物
WO2008002514A2 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6014045551; USMANI, O.S. et al: 'Theobromine inhibits sensory nerve activation and cough' FASEB J. Vol.19, No.2, 2005, p.231-233 *
JPN6014045554; GRATTAN, T.J. et al: 'The effect of inhaled and oral dextromethorphan on citric acid induced cough in man' Br. J. Clin. Pharmacol. Vol.39, No.3, 1995, p.261-263 *
JPN6014045556; BROWN, C. et al: 'Antitussive activity of sigma-1 receptor agonists in the guinea-pig' Br. J. Pharmacol. Vol.141, No.2, 2004, p.233-240 *

Also Published As

Publication number Publication date
CA2780703A1 (en) 2011-05-19
RU2519086C2 (ru) 2014-06-10
JP2016128439A (ja) 2016-07-14
CO6551744A2 (es) 2012-10-31
EP2498777A2 (en) 2012-09-19
GB0919889D0 (en) 2009-12-30
NZ599949A (en) 2013-08-30
ZA201204248B (en) 2013-02-27
WO2011058373A2 (en) 2011-05-19
PE20130147A1 (es) 2013-03-13
BR112012011227A2 (pt) 2017-06-13
IL219768A0 (en) 2012-07-31
WO2011058373A3 (en) 2011-07-07
RU2012124038A (ru) 2013-12-20
UA108993C2 (en) 2015-07-10
AU2010317667B2 (en) 2014-05-29
CN102753174A (zh) 2012-10-24
JP6118919B2 (ja) 2017-04-19
MX2012005532A (es) 2012-09-28
PH12012501369A1 (en) 2012-10-22
AU2010317667A1 (en) 2012-06-07

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