NZ599949A - Drug combination with theobromine and its use in therapy - Google Patents

Drug combination with theobromine and its use in therapy

Info

Publication number
NZ599949A
NZ599949A NZ599949A NZ59994910A NZ599949A NZ 599949 A NZ599949 A NZ 599949A NZ 599949 A NZ599949 A NZ 599949A NZ 59994910 A NZ59994910 A NZ 59994910A NZ 599949 A NZ599949 A NZ 599949A
Authority
NZ
New Zealand
Prior art keywords
therapy
theobromine
drug combination
opiate antitussive
meprotixol
Prior art date
Application number
NZ599949A
Inventor
John Brew
Robin Mark Bannister
Original Assignee
Biocopea Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41509324&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ599949(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biocopea Ltd filed Critical Biocopea Ltd
Publication of NZ599949A publication Critical patent/NZ599949A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Abstract 599949 The disclosure relates to an agent consisting of theobromine and another non-opiate antitussive, for use in therapy. Preferably, the therapy is of cough. The non-opiate antitussive (preferably a N-methyl-D-aspartate [NMDA] receptor antagonist) may be any of dextromethorphan, isoaminile, benzonate, zipeprol, morclofone, prenoxdiazine, dropropizine, piperidione, pentoxyverine, oxolamine, oxeladin, nepinalone, meprotixol, indantadol, dimemorfan, dibunate, cloperastine, clofedanol, butamirate, bibenzonium, benproperine and fedrilate.
NZ599949A 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy NZ599949A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0919889.6A GB0919889D0 (en) 2009-11-13 2009-11-13 Drug composition and its use in therapy
PCT/GB2010/051895 WO2011058373A2 (en) 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy

Publications (1)

Publication Number Publication Date
NZ599949A true NZ599949A (en) 2013-08-30

Family

ID=41509324

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ599949A NZ599949A (en) 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy

Country Status (16)

Country Link
EP (1) EP2498777A2 (en)
JP (2) JP2013510841A (en)
CN (1) CN102753174A (en)
AU (1) AU2010317667B2 (en)
BR (1) BR112012011227A2 (en)
CA (1) CA2780703A1 (en)
CO (1) CO6551744A2 (en)
GB (1) GB0919889D0 (en)
IL (1) IL219768A0 (en)
MX (1) MX2012005532A (en)
NZ (1) NZ599949A (en)
PE (1) PE20130147A1 (en)
RU (1) RU2519086C2 (en)
UA (1) UA108993C2 (en)
WO (1) WO2011058373A2 (en)
ZA (1) ZA201204248B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
WO2017117347A1 (en) * 2015-12-30 2017-07-06 Markovitz M D Paul Method of treating schizophrenia

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834479A (en) * 1993-03-05 1998-11-10 Mayer; David J. Method and composition for alleviating pain
EP0944604B1 (en) * 1996-11-25 2005-01-12 The Procter & Gamble Company Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists
HUP9700654A2 (en) * 1997-03-26 1999-09-28 Dezső Korbonits Antitussive compositions containing theobromine
US20030206942A1 (en) * 1998-09-25 2003-11-06 Neema Kulkarni Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent
US6207674B1 (en) * 1999-12-22 2001-03-27 Richard A. Smith Dextromethorphan and oxidase inhibitor for weaning patients from narcotics and anti-depressants
DE602004013011D1 (en) * 2003-05-29 2008-05-21 Unilever Nv HAIR TREATMENT COMPOSITIONS
US20060153926A1 (en) * 2005-01-10 2006-07-13 Bascom Charles C Compositions, products and methods for controlling weight in a mammal
US20080003280A1 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs
US20080176955A1 (en) * 2007-01-16 2008-07-24 Victory Pharma, Inc. Combined administration of benzonatate and guaifenesin

Also Published As

Publication number Publication date
UA108993C2 (en) 2015-07-10
IL219768A0 (en) 2012-07-31
CA2780703A1 (en) 2011-05-19
RU2012124038A (en) 2013-12-20
ZA201204248B (en) 2013-02-27
WO2011058373A3 (en) 2011-07-07
BR112012011227A2 (en) 2017-06-13
RU2519086C2 (en) 2014-06-10
MX2012005532A (en) 2012-09-28
EP2498777A2 (en) 2012-09-19
CO6551744A2 (en) 2012-10-31
JP2016128439A (en) 2016-07-14
AU2010317667A1 (en) 2012-06-07
WO2011058373A2 (en) 2011-05-19
JP2013510841A (en) 2013-03-28
PE20130147A1 (en) 2013-03-13
AU2010317667B2 (en) 2014-05-29
CN102753174A (en) 2012-10-24
JP6118919B2 (en) 2017-04-19
GB0919889D0 (en) 2009-12-30

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Effective date: 20141012

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Owner name: INFIRST HEALTHCARE LIMITED, GB

Effective date: 20141106

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Effective date: 20151103

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