PE20130147A1 - PHARMACEUTICAL COMBINATION OF THEOBROMINE AND A NON-OPIOID ANTITUSSIVE AGENT - Google Patents
PHARMACEUTICAL COMBINATION OF THEOBROMINE AND A NON-OPIOID ANTITUSSIVE AGENTInfo
- Publication number
- PE20130147A1 PE20130147A1 PE2012000649A PE2012000649A PE20130147A1 PE 20130147 A1 PE20130147 A1 PE 20130147A1 PE 2012000649 A PE2012000649 A PE 2012000649A PE 2012000649 A PE2012000649 A PE 2012000649A PE 20130147 A1 PE20130147 A1 PE 20130147A1
- Authority
- PE
- Peru
- Prior art keywords
- theobromine
- pharmaceutical combination
- opioid
- antitussive agent
- combination
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
SE REFIERE A UNA COMBINACION FARMACEUTICA QUE COMPRENDE A) TEOBROMINA; Y B) UN ANTITUSIVO NO OPIATO TAL COMO DEXTROMETORFANO, ISOAMILO, MORCLOFONA, CLOFEDANOL, ENTRE OTROS, EN UNA CANTIDAD DE 0,1 A 30 MG/KG/DIA. DICHA COMBINACION PRESENTA UN EFECTO SINERGICO A COMPARACION DE LA ADMINISTRACION POR SEPARADO Y REDUCE LAS DOSIS INDIVIDUALES EN EL TRATAMIENTO DE LA TOSIT REFERS TO A PHARMACEUTICAL COMBINATION THAT INCLUDES A) THEOBROMINE; AND B) A NON-OPIATE ANTITUSSIVE SUCH AS DEXTROMETORPHANE, ISOAMYL, MORCHLOFONE, CLOFEDANOL, AMONG OTHERS, IN AN AMOUNT OF 0.1 TO 30 MG / KG / DAY. SUCH COMBINATION PRESENTS A SYNERGIC EFFECT IN COMPARISON OF SEPARATE ADMINISTRATION AND REDUCES INDIVIDUAL DOSES IN THE TREATMENT OF COUGH
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0919889.6A GB0919889D0 (en) | 2009-11-13 | 2009-11-13 | Drug composition and its use in therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20130147A1 true PE20130147A1 (en) | 2013-03-13 |
Family
ID=41509324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2012000649A PE20130147A1 (en) | 2009-11-13 | 2010-11-12 | PHARMACEUTICAL COMBINATION OF THEOBROMINE AND A NON-OPIOID ANTITUSSIVE AGENT |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP2498777A2 (en) |
JP (2) | JP2013510841A (en) |
CN (1) | CN102753174A (en) |
AU (1) | AU2010317667B2 (en) |
BR (1) | BR112012011227A2 (en) |
CA (1) | CA2780703A1 (en) |
CO (1) | CO6551744A2 (en) |
GB (1) | GB0919889D0 (en) |
IL (1) | IL219768A0 (en) |
MX (1) | MX2012005532A (en) |
NZ (1) | NZ599949A (en) |
PE (1) | PE20130147A1 (en) |
RU (1) | RU2519086C2 (en) |
UA (1) | UA108993C2 (en) |
WO (1) | WO2011058373A2 (en) |
ZA (1) | ZA201204248B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0910375D0 (en) | 2009-06-16 | 2009-07-29 | Biocopea Ltd | Drug composition and its use in therapy |
US9314465B2 (en) | 2009-06-16 | 2016-04-19 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
US9308211B2 (en) | 2009-06-16 | 2016-04-12 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
US10016437B2 (en) | 2009-06-16 | 2018-07-10 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
GB201111485D0 (en) * | 2011-07-05 | 2011-08-17 | Biocopea Ltd | Drug composition and its use in therapy |
WO2017117347A1 (en) * | 2015-12-30 | 2017-07-06 | Markovitz M D Paul | Method of treating schizophrenia |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5834479A (en) * | 1993-03-05 | 1998-11-10 | Mayer; David J. | Method and composition for alleviating pain |
RU2194700C2 (en) * | 1996-11-25 | 2002-12-20 | Дзе Проктер Энд Гэмбл Компани | Guanidyl heterocyclic compounds using as agonists of alpha-2 adrenoceptors |
HUP9700654A2 (en) * | 1997-03-26 | 1999-09-28 | Dezső Korbonits | Antitussive compositions containing theobromine |
US20030206942A1 (en) * | 1998-09-25 | 2003-11-06 | Neema Kulkarni | Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent |
US6207674B1 (en) * | 1999-12-22 | 2001-03-27 | Richard A. Smith | Dextromethorphan and oxidase inhibitor for weaning patients from narcotics and anti-depressants |
WO2004105705A1 (en) * | 2003-05-29 | 2004-12-09 | Unilever Plc | Hair treatment compositions |
US20060153926A1 (en) * | 2005-01-10 | 2006-07-13 | Bascom Charles C | Compositions, products and methods for controlling weight in a mammal |
US20080003280A1 (en) * | 2006-06-26 | 2008-01-03 | Levine Brian M | Combination cough treatment compounds and method of treating common coughs |
US20080176955A1 (en) * | 2007-01-16 | 2008-07-24 | Victory Pharma, Inc. | Combined administration of benzonatate and guaifenesin |
-
2009
- 2009-11-13 GB GBGB0919889.6A patent/GB0919889D0/en not_active Ceased
-
2010
- 2010-11-12 CA CA2780703A patent/CA2780703A1/en not_active Abandoned
- 2010-11-12 MX MX2012005532A patent/MX2012005532A/en active IP Right Grant
- 2010-11-12 RU RU2012124038/15A patent/RU2519086C2/en not_active IP Right Cessation
- 2010-11-12 PE PE2012000649A patent/PE20130147A1/en not_active Application Discontinuation
- 2010-11-12 AU AU2010317667A patent/AU2010317667B2/en not_active Ceased
- 2010-11-12 EP EP10825831A patent/EP2498777A2/en not_active Ceased
- 2010-11-12 CN CN2010800516299A patent/CN102753174A/en active Pending
- 2010-11-12 WO PCT/GB2010/051895 patent/WO2011058373A2/en active Application Filing
- 2010-11-12 BR BR112012011227A patent/BR112012011227A2/en not_active IP Right Cessation
- 2010-11-12 JP JP2012538415A patent/JP2013510841A/en active Pending
- 2010-11-12 NZ NZ599949A patent/NZ599949A/en not_active IP Right Cessation
- 2010-12-11 UA UAA201207164A patent/UA108993C2/en unknown
-
2012
- 2012-05-11 CO CO12078027A patent/CO6551744A2/en not_active Application Discontinuation
- 2012-05-13 IL IL219768A patent/IL219768A0/en unknown
- 2012-06-11 ZA ZA2012/04248A patent/ZA201204248B/en unknown
-
2016
- 2016-01-07 JP JP2016001487A patent/JP6118919B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CO6551744A2 (en) | 2012-10-31 |
EP2498777A2 (en) | 2012-09-19 |
ZA201204248B (en) | 2013-02-27 |
JP6118919B2 (en) | 2017-04-19 |
WO2011058373A2 (en) | 2011-05-19 |
WO2011058373A3 (en) | 2011-07-07 |
RU2519086C2 (en) | 2014-06-10 |
JP2016128439A (en) | 2016-07-14 |
JP2013510841A (en) | 2013-03-28 |
GB0919889D0 (en) | 2009-12-30 |
AU2010317667A1 (en) | 2012-06-07 |
CA2780703A1 (en) | 2011-05-19 |
CN102753174A (en) | 2012-10-24 |
AU2010317667B2 (en) | 2014-05-29 |
MX2012005532A (en) | 2012-09-28 |
BR112012011227A2 (en) | 2017-06-13 |
IL219768A0 (en) | 2012-07-31 |
UA108993C2 (en) | 2015-07-10 |
RU2012124038A (en) | 2013-12-20 |
NZ599949A (en) | 2013-08-30 |
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Legal Events
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FC | Refusal |