JP2013510841A5 - - Google Patents
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- Publication number
- JP2013510841A5 JP2013510841A5 JP2012538415A JP2012538415A JP2013510841A5 JP 2013510841 A5 JP2013510841 A5 JP 2013510841A5 JP 2012538415 A JP2012538415 A JP 2012538415A JP 2012538415 A JP2012538415 A JP 2012538415A JP 2013510841 A5 JP2013510841 A5 JP 2013510841A5
- Authority
- JP
- Japan
- Prior art keywords
- day
- opiate
- medicament
- dextromethorphan
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 12
- 230000000954 anitussive effect Effects 0.000 claims 10
- 229940124584 antitussives Drugs 0.000 claims 10
- 230000000631 nonopiate Effects 0.000 claims 10
- -1 isoaminyl Chemical compound 0.000 claims 9
- MKXZASYAUGDDCJ-SZMVWBNQSA-N LSM-2525 Chemical compound C1CCC[C@H]2[C@@]3([H])N(C)CC[C@]21C1=CC(OC)=CC=C1C3 MKXZASYAUGDDCJ-SZMVWBNQSA-N 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 6
- 229960001985 dextromethorphan Drugs 0.000 claims 6
- 239000003434 antitussive agent Substances 0.000 claims 5
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- YAPQBXQYLJRXSA-UHFFFAOYSA-N theobromine Chemical compound CN1C(=O)NC(=O)C2=C1N=CN2C YAPQBXQYLJRXSA-UHFFFAOYSA-N 0.000 claims 4
- 206010011224 Cough Diseases 0.000 claims 3
- 239000002775 capsule Substances 0.000 claims 3
- 229940079593 drug Drugs 0.000 claims 3
- 239000000839 emulsion Substances 0.000 claims 3
- 239000008187 granular material Substances 0.000 claims 3
- 239000007937 lozenge Substances 0.000 claims 3
- 239000000843 powder Substances 0.000 claims 3
- 239000000725 suspension Substances 0.000 claims 3
- 239000006188 syrup Substances 0.000 claims 3
- 235000020357 syrup Nutrition 0.000 claims 3
- 239000003826 tablet Substances 0.000 claims 3
- JTUQXGZRVLWBCR-UHFFFAOYSA-N 1-[1-[2-(phenylmethyl)phenoxy]propan-2-yl]piperidine Chemical compound C1CCCCN1C(C)COC1=CC=CC=C1CC1=CC=CC=C1 JTUQXGZRVLWBCR-UHFFFAOYSA-N 0.000 claims 2
- FLNXBVJLPJNOSI-UHFFFAOYSA-N 1-[2-[(4-chlorophenyl)-phenylmethoxy]ethyl]piperidine Chemical compound C1=CC(Cl)=CC=C1C(C=1C=CC=CC=1)OCCN1CCCCC1 FLNXBVJLPJNOSI-UHFFFAOYSA-N 0.000 claims 2
- IDCHQQSVJAAUQQ-UHFFFAOYSA-N N,N-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine Chemical compound O1C(CCN(CC)CC)=NC(C=2C=CC=CC=2)=N1 IDCHQQSVJAAUQQ-UHFFFAOYSA-N 0.000 claims 2
- 229940099433 NMDA receptor antagonist Drugs 0.000 claims 2
- RGEVWUKXWFOAID-UHFFFAOYSA-N Piperidione Chemical compound CCC1(CC)C(=O)CCNC1=O RGEVWUKXWFOAID-UHFFFAOYSA-N 0.000 claims 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims 2
- 229960002544 cloperastine Drugs 0.000 claims 2
- 229960000295 dibunate Drugs 0.000 claims 2
- WBEBQCINXJDZCX-UHFFFAOYSA-N dibunic acid Chemical compound OS(=O)(=O)C1=C(C(C)(C)C)C=CC2=CC(C(C)(C)C)=CC=C21 WBEBQCINXJDZCX-UHFFFAOYSA-N 0.000 claims 2
- 229960001056 dimemorfan Drugs 0.000 claims 2
- KBEZZLAAKIIPFK-NJAFHUGGSA-N dimemorfan Chemical compound C1C2=CC=C(C)C=C2[C@@]23CCN(C)[C@@H]1[C@H]2CCCC3 KBEZZLAAKIIPFK-NJAFHUGGSA-N 0.000 claims 2
- 229950008308 indantadol Drugs 0.000 claims 2
- MNLULKBKWKTZPE-UHFFFAOYSA-N indantadol Chemical compound C1=CC=C2CC(NCC(=O)N)CC2=C1 MNLULKBKWKTZPE-UHFFFAOYSA-N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229960002732 meprotixol Drugs 0.000 claims 2
- LAYVFLWAVIGDLK-UHFFFAOYSA-N meprotixol Chemical compound C1=CC=C2C(O)(CCCN(C)C)C3=CC(OC)=CC=C3SC2=C1 LAYVFLWAVIGDLK-UHFFFAOYSA-N 0.000 claims 2
- 239000003703 n methyl dextro aspartic acid receptor blocking agent Substances 0.000 claims 2
- 229960003427 nepinalone Drugs 0.000 claims 2
- RVXGRCNWGOHSDE-UHFFFAOYSA-N nepinalone Chemical compound O=C1CCC2=CC=CC=C2C1(C)CCN1CCCCC1 RVXGRCNWGOHSDE-UHFFFAOYSA-N 0.000 claims 2
- 229960003625 oxolamine Drugs 0.000 claims 2
- 229960003810 piperidione Drugs 0.000 claims 2
- 229960004559 theobromine Drugs 0.000 claims 2
- 229960001871 benproperine Drugs 0.000 claims 1
- LBRNZQRZDLLIHL-UHFFFAOYSA-N bibenzonium Chemical compound C=1C=CC=CC=1C(OCC[N+](C)(C)C)CC1=CC=CC=C1 LBRNZQRZDLLIHL-UHFFFAOYSA-N 0.000 claims 1
- 229950003903 bibenzonium Drugs 0.000 claims 1
- DDVUMDPCZWBYRA-UHFFFAOYSA-N butamirate Chemical compound CCN(CC)CCOCCOC(=O)C(CC)C1=CC=CC=C1 DDVUMDPCZWBYRA-UHFFFAOYSA-N 0.000 claims 1
- 239000003086 colorant Substances 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000013355 food flavoring agent Nutrition 0.000 claims 1
- 235000003599 food sweetener Nutrition 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000003765 sweetening agent Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0919889.6A GB0919889D0 (en) | 2009-11-13 | 2009-11-13 | Drug composition and its use in therapy |
| GB0919889.6 | 2009-11-13 | ||
| PCT/GB2010/051895 WO2011058373A2 (en) | 2009-11-13 | 2010-11-12 | Drug combination with theobromine and its use in therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016001487A Division JP6118919B2 (ja) | 2009-11-13 | 2016-01-07 | テオブロミンとの薬物組み合わせおよび治療におけるその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013510841A JP2013510841A (ja) | 2013-03-28 |
| JP2013510841A5 true JP2013510841A5 (enExample) | 2013-12-26 |
Family
ID=41509324
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012538415A Pending JP2013510841A (ja) | 2009-11-13 | 2010-11-12 | テオブロミンとの薬物組み合わせおよび治療におけるその使用 |
| JP2016001487A Active JP6118919B2 (ja) | 2009-11-13 | 2016-01-07 | テオブロミンとの薬物組み合わせおよび治療におけるその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016001487A Active JP6118919B2 (ja) | 2009-11-13 | 2016-01-07 | テオブロミンとの薬物組み合わせおよび治療におけるその使用 |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP2498777A2 (enExample) |
| JP (2) | JP2013510841A (enExample) |
| CN (1) | CN102753174A (enExample) |
| AU (1) | AU2010317667B2 (enExample) |
| BR (1) | BR112012011227A2 (enExample) |
| CA (1) | CA2780703A1 (enExample) |
| CO (1) | CO6551744A2 (enExample) |
| GB (1) | GB0919889D0 (enExample) |
| IL (1) | IL219768A0 (enExample) |
| MX (1) | MX2012005532A (enExample) |
| NZ (1) | NZ599949A (enExample) |
| PE (1) | PE20130147A1 (enExample) |
| PH (1) | PH12012501369A1 (enExample) |
| RU (1) | RU2519086C2 (enExample) |
| UA (1) | UA108993C2 (enExample) |
| WO (1) | WO2011058373A2 (enExample) |
| ZA (1) | ZA201204248B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10016437B2 (en) | 2009-06-16 | 2018-07-10 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
| GB201111485D0 (en) * | 2011-07-05 | 2011-08-17 | Biocopea Ltd | Drug composition and its use in therapy |
| US9308211B2 (en) | 2009-06-16 | 2016-04-12 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
| US9314465B2 (en) | 2009-06-16 | 2016-04-19 | Infirst Healthcare Limited | Drug combinations and uses in treating a coughing condition |
| GB0910375D0 (en) | 2009-06-16 | 2009-07-29 | Biocopea Ltd | Drug composition and its use in therapy |
| WO2017117347A1 (en) * | 2015-12-30 | 2017-07-06 | Markovitz M D Paul | Method of treating schizophrenia |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5834479A (en) * | 1993-03-05 | 1998-11-10 | Mayer; David J. | Method and composition for alleviating pain |
| CA2272640C (en) * | 1996-11-25 | 2003-07-08 | The Procter & Gamble Company | Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists |
| HUP9700654A2 (hu) * | 1997-03-26 | 1999-09-28 | Dezső Korbonits | Teobromin tartalmú köhögéscsillapító készítmények |
| US20030206942A1 (en) * | 1998-09-25 | 2003-11-06 | Neema Kulkarni | Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent |
| US6207674B1 (en) * | 1999-12-22 | 2001-03-27 | Richard A. Smith | Dextromethorphan and oxidase inhibitor for weaning patients from narcotics and anti-depressants |
| WO2004105705A1 (en) * | 2003-05-29 | 2004-12-09 | Unilever Plc | Hair treatment compositions |
| US20060153926A1 (en) * | 2005-01-10 | 2006-07-13 | Bascom Charles C | Compositions, products and methods for controlling weight in a mammal |
| US20080003280A1 (en) * | 2006-06-26 | 2008-01-03 | Levine Brian M | Combination cough treatment compounds and method of treating common coughs |
| US20080176955A1 (en) * | 2007-01-16 | 2008-07-24 | Victory Pharma, Inc. | Combined administration of benzonatate and guaifenesin |
-
2009
- 2009-11-13 GB GBGB0919889.6A patent/GB0919889D0/en not_active Ceased
-
2010
- 2010-11-12 EP EP10825831A patent/EP2498777A2/en not_active Ceased
- 2010-11-12 NZ NZ599949A patent/NZ599949A/xx not_active IP Right Cessation
- 2010-11-12 CN CN2010800516299A patent/CN102753174A/zh active Pending
- 2010-11-12 WO PCT/GB2010/051895 patent/WO2011058373A2/en not_active Ceased
- 2010-11-12 PE PE2012000649A patent/PE20130147A1/es not_active Application Discontinuation
- 2010-11-12 PH PH1/2012/501369A patent/PH12012501369A1/en unknown
- 2010-11-12 AU AU2010317667A patent/AU2010317667B2/en not_active Ceased
- 2010-11-12 JP JP2012538415A patent/JP2013510841A/ja active Pending
- 2010-11-12 MX MX2012005532A patent/MX2012005532A/es active IP Right Grant
- 2010-11-12 BR BR112012011227A patent/BR112012011227A2/pt not_active IP Right Cessation
- 2010-11-12 CA CA2780703A patent/CA2780703A1/en not_active Abandoned
- 2010-11-12 RU RU2012124038/15A patent/RU2519086C2/ru not_active IP Right Cessation
- 2010-12-11 UA UAA201207164A patent/UA108993C2/en unknown
-
2012
- 2012-05-11 CO CO12078027A patent/CO6551744A2/es not_active Application Discontinuation
- 2012-05-13 IL IL219768A patent/IL219768A0/en unknown
- 2012-06-11 ZA ZA2012/04248A patent/ZA201204248B/en unknown
-
2016
- 2016-01-07 JP JP2016001487A patent/JP6118919B2/ja active Active
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